Works Published in 2019
Displaying works 1 - 20 of 147 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 article
The Periostin Activation of Integrin Receptors on Sensory Neurons Induces Allergic Itch
SSRN.
Contributors: S. Mishra n, J. Wheeler n, S. Pitake n, H. Ding *, C. Jiang *, T. Fukuyama n, J. Paps n, P. Ralph n
refubium.fu-berlin.de (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: March 8, 2024
2019 chapter
Inhalation of Lung Spheroid Cell-Secretome and Exosomes Promotes Therapeutic Lung Repair in Rodent Models of Pulmonary Fibrosis
In A29 Emerging Concepts in Lung Fibrosis (Vol. 199, pp. 1225–1225).
Event: American Thoracic Society International Conference
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: NC State University Libraries, NC State University Libraries
Added: May 23, 2023
2019 article
Delivery of MSCs with a Hybrid β-Sheet Peptide Hydrogel Consisting IGF-1C Domain and D-Form Peptide for Acute Kidney Injury Therapy
SSRN.
Contributors: H. Wang *, Y. Shang *, X. Chen*, Z. Wang*, D. Zhu* , Y. Liu *, C. Zhang *, P. Chen *
Source: ORCID
Added: April 19, 2023
2019 journal article
Targeted delivery of nitric oxide via a ‘bump-and-hole’-based enzyme–prodrug pair
Nature Chemical Biology, 15(2), 151–160.
MeSH headings : Animals; Azo Compounds; Drug Delivery Systems / methods; Galactosidases; Male; Mice; Mice, Inbred C57BL; Mice, Nude; Nitric Oxide / administration & dosage; Nitric Oxide / metabolism; Nitric Oxide / physiology; Prodrugs; Rats; Rats, Sprague-Dawley; beta-Galactosidase / metabolism; beta-Galactosidase / physiology
TL;DR:
A novel NO delivery system that depends on the hydrolysis of an alkyl-galactose-conjugated NO prodrug by an engineered galactosidase developed using a ‘bump-and-hole’ strategy enabled targeted delivery of NO to specific tissues.
(via Semantic Scholar)
Source: ORCID
Added: April 19, 2023
2019 journal article
Preparation of levodopa-loaded crystalsomes through thermally induced crystallization reverses functional deficits in Parkinsonian mice
Biomaterials Science, 7(4), 1623–1631.
MeSH headings : Animals; Antiparkinson Agents / chemical synthesis; Antiparkinson Agents / chemistry; Antiparkinson Agents / therapeutic use; Crystallization; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers / chemistry; Emulsions / chemical synthesis; Emulsions / chemistry; Emulsions / therapeutic use; Female; Levodopa / chemical synthesis; Levodopa / chemistry; Levodopa / therapeutic use; Mice; Mice, Inbred BALB C; Molecular Structure; Nanoparticles / chemistry; Parkinson Disease / drug therapy; Structure-Activity Relationship; Temperature
TL;DR:
Levodopa-loaded crystallization nanoparticles (LD crystalsomes) were prepared by a mini-emulsion crystallization method and exhibited a positive zeta potential, nanoscale range and longer releasing time for levodopa (LD).
(via Semantic Scholar)
Source: ORCID
Added: April 19, 2023
2019 journal article
Resveratrol synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson disease in mice
Behavioural Brain Research, 367, 10–18.
MeSH headings : Animals; Antioxidants / administration & dosage; Antioxidants / pharmacology; Antiparkinson Agents / administration & dosage; Antiparkinson Agents / pharmacology; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Female; Levodopa / administration & dosage; Levodopa / pharmacology; MPTP Poisoning / drug therapy; Mice; Mice, Inbred BALB C; Resveratrol / administration & dosage; Resveratrol / pharmacology
TL;DR:
RV significantly reduced motor dysfunction in MPTP‐treated mice, and the RV‐treated group showed less IL‐1&bgr; and an enhanced pAkt/Akt ratio, which promoted dopamine neuron survival in the striatum.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: April 19, 2023
2019 journal article
A collagen hydrogel loaded with HDAC7-derived peptide promotes the regeneration of infarcted myocardium with functional improvement in a rodent model
Acta Biomaterialia, 86, 223–234.
MeSH headings : Animals; Apoptosis / drug effects; Cell Differentiation / drug effects; Cell Survival / drug effects; Collagen / pharmacology; Culture Media, Serum-Free; Disease Models, Animal; Female; Histone Deacetylases / chemistry; Hydrogels / pharmacology; Mice, Inbred C57BL; Myocardial Infarction / physiopathology; Myocytes, Cardiac / drug effects; Myocytes, Cardiac / pathology; Neovascularization, Physiologic / drug effects; Peptides / pharmacology; Rats; Recovery of Function / drug effects; Regeneration / drug effects; Stem Cells / cytology; Stem Cells / drug effects; Ventricular Function / drug effects
TL;DR:
In vivo investigations in a mouse MI model demonstrated that intra-myocardial delivery of 7Ap-loaded collagen hydrogel promoted neovascularization, stimulated Sca-l+ stem cell recruitment and differentiation, reduced cardiomyocyte apoptosis and promoted cell cycle progression, and 7Ap was shown to improve H9C2 cell survival, in vitro.
(via Semantic Scholar)
Source: ORCID
Added: April 19, 2023
2019 journal article
Lactobacillus maintains healthy gut mucosa by producing L-Ornithine
Communications Biology, 2(1).
Contributors: H. Qi*, Y. Li *, H. Yun*, T. Zhang *, Y. Huang *, J. Zhou *, H. Yan *, J. Wei *
MeSH headings : Animals; Basic Helix-Loop-Helix Transcription Factors / metabolism; Epithelial Cells / immunology; Epithelial Cells / metabolism; Epithelial Cells / microbiology; Female; Gastrointestinal Microbiome / immunology; Gastrointestinal Microbiome / physiology; Germ-Free Life; Homeostasis; Humans; Intestinal Mucosa / immunology; Intestinal Mucosa / metabolism; Intestinal Mucosa / microbiology; Lactobacillus / immunology; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mucus / metabolism; Nuclear Receptor Subfamily 1, Group F, Member 3 / metabolism; Ornithine / biosynthesis; Pancreatitis-Associated Proteins / genetics; Pancreatitis-Associated Proteins / metabolism; Receptors, Aryl Hydrocarbon / metabolism
TL;DR:
It is shown that lactobacilli promote the generation of gut mucosa by facilitating the conversion of arginine to L-Ornithine, and implicates the importance of a crosstalk betweenArginine metabolism in LactOBacilli and tryptophan metabolism in gut epithelial cells in maintaining a healthy gut barrier.
(via Semantic Scholar)
Source: ORCID
Added: April 19, 2023
2019 book
Molecular Biology Techniques 4th Edition
In Elsevier. https://www.elsevier.com/books/molecular-biology-techniques/carson/978-0-12-815774-9
Source: ORCID
Added: June 25, 2021
2019 journal article
Tissue-specific changes in size and shape of the ligaments and tendons of the porcine knee during post-natal growth
PLOS ONE, 14(10).
MeSH headings : Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament / growth & development; Female; Knee Joint / diagnostic imaging; Knee Joint / growth & development; Magnetic Resonance Imaging; Organ Specificity; Patellar Ligament / diagnostic imaging; Patellar Ligament / growth & development; Swine
TL;DR:
The findings suggest that musculoskeletal soft tissue morphometry can vary within tissues of similar structure and within a single joint during post-natal growth.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: June 8, 2020
2019 journal article
Ceftiofur formulation differentially affects the intestinal drug concentration, resistance of fecal Escherichia coli, and the microbiome of steers
PLOS ONE, 14(10).
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Anti-Bacterial Agents / pharmacokinetics; Cattle; Cattle Diseases / drug therapy; Cattle Diseases / microbiology; Cephalosporins / administration & dosage; Cephalosporins / chemistry; Cephalosporins / pharmacokinetics; Drug Resistance, Bacterial; Escherichia coli / classification; Escherichia coli / drug effects; Escherichia coli / genetics; Feces / microbiology; Microbial Sensitivity Tests; Microbiota; RNA, Ribosomal, 16S / genetics
TL;DR:
CCFA leads to prolonged, low intestinal drug concentrations, and is associated with decreased E. coli concentration, an increased MIC of ceftiofur in E. Escherichia coli at specific time points, and shifts in the fecal microbiota.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: June 1, 2020
2019 journal article
Loss of ATM positively regulates Rac1 activity and cellular migration through oxidative stress
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 508(4), 1155–1161.
author keywords: ATM; Rac1; Reactive oxygen species; Migration
MeSH headings : Animals; Ataxia Telangiectasia Mutated Proteins / metabolism; Cell Movement; Enzyme Activation; HeLa Cells; Humans; Oxidative Stress; Rats; Reactive Oxygen Species / metabolism; rac1 GTP-Binding Protein / metabolism
TL;DR:
It is shown that loss of ATM kinase activity elevates intracellular ROS, leading to Rac1 activation, which drives cytoskeletal rearrangements resulting in increased cellular spreading and motility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: April 20, 2020
2019 journal article
Pharmacokinetics of levofloxacin following oral administration of a generic levofloxacin tablet and intravenous administration to dogs
AMERICAN JOURNAL OF VETERINARY RESEARCH, 80(10), 957–962.
MeSH headings : Administration, Intravenous; Administration, Oral; Animals; Anti-Bacterial Agents / pharmacokinetics; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid / veterinary; Cross-Over Studies; Dogs / metabolism; Female; Half-Life; Levofloxacin / administration & dosage; Levofloxacin / pharmacokinetics; Male; Tablets
TL;DR:
In these dogs, levofloxacin was well absorbed when administered orally, and a dose of approximately 25 mg/kg was sufficient to reach pharmacokinetic-pharmacodynamic targets for treating infections with susceptible Enterobacteriaceae or Pseudomonas aeruginosa.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 20, 2020
2019 journal article
Oxygen and hydrogen isotopes in human hair and tap water: Modeling relationships in a modern Mexican population
Human Biology, 90(3), 197–211.
Contributors: C. Juarez, R. Ramey, D. Flaherty & B. Akpa*
author keywords: delta H-2; delta O-18; MEXICO; TAP WATER; HAIR
TL;DR:
Data from this Mexican population did not exhibit the strong relationships between isotope values of 18O and 2H in tap water and hair that have been characteristic of other populations studied to date, and the results with parameters based on the American supermarket diet were disappointing.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
14. Life Below Water
(Web of Science)
Source: ORCID
Added: April 7, 2020
2019 book
Pharmacotherapeutics for Veterinary Dispensing
In PHARMACOTHERAPEUTICS FOR VETERINARY DISPENSING (pp. 1–623).
Source: Web Of Science
Added: February 27, 2020
2019 journal article
USE OF A GASTROSTOMY AND JEJUNOSTOMY TUBE FOR MANAGEMENT OF GASTRIC DISTENTION FOLLOWING PYLORIC OUTFLOW OBSTRUCTION IN A FERRET (MUSTELA PUTORIUS FURO)
Journal of Exotic Pet Medicine, 28, 105–110.
author keywords: Feeding tube; ferret; gastrostomy; jejunostomy; Mustela putorius furo
TL;DR:
Feeding tubes and supplemental nutrition plans should be considered for management of ferrets with compatible disease processes after successful management of idiopathic gastric distention using gastric and jejunal feeding tubes in a ferret.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science; OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 21, 2020
2019 journal article
200 Developing exosomes as a mediator for CRISPR/Cas-9 delivery
Reproduction, Fertility and Development, 31(1), 225.
TL;DR:
This project uses exosomes as a delivery system for Cas9, exploiting their high uptake by target cells and their ability to avoid the immune system in vivo, and hypothesise that based on loading efficiency and target cell uptake, exosome will present a safe and efficient method for in vitro and in vivo delivery of Cas9.
(via Semantic Scholar)
Source: Crossref
Added: February 21, 2020
2019 journal article
Porous Organic Polymer-Coated Band-Aids for Phototherapy of Bacteria-Induced Wound Infection
ACS Applied Bio Materials, 2(2), 613–618.
author keywords: wound infection; porous organic polymers; Band-Aids; white light
TL;DR:
Bacterial Band-Aids, combining porphyrin-based porous organic polymers (POPs) with commercial antibiotic-free Band- Aids, are designed, which are ideal wound dressings for wound disinfection under white light irradiation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: February 21, 2020
2019 journal article
Biomimetics: Platelet-Inspired Nanocells for Targeted Heart Repair After Ischemia/Reperfusion Injury (Adv. Funct. Mater. 4/2019)
Advanced Functional Materials, 29(4), 1970019.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: February 21, 2020
2019 journal article
The effect of aquapuncture at Pericardium 6 (PC-6) on dexmedetomidine-induced nausea and vomiting in cats
Veterinary Anaesthesia and Analgesia, 46(3), 308–314.
author keywords: antiemetic; cat; dexmedetomidine; PC-6; vomiting
MeSH headings : Acupressure / methods; Acupressure / veterinary; Acupuncture Points; Adrenergic alpha-2 Receptor Agonists / adverse effects; Animals; Cats; Cross-Over Studies; Dexmedetomidine / adverse effects; Dexmedetomidine / antagonists & inhibitors; Female; Incidence; Male; Nausea / chemically induced; Nausea / epidemiology; Nausea / prevention & control; Nausea / veterinary; Pericardium; Prospective Studies; Random Allocation; Vomiting / chemically induced; Vomiting / epidemiology; Vomiting / prevention & control; Vomiting / veterinary
TL;DR:
PC-6 aquapuncture did not reduce the incidence of dexmedetomidine-induced vomiting or severity of nausea in cats and a regression model was used to detect the influence of aquapunct on vomiting and nausea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: February 21, 2020
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