TY - CONF TI - Pharmacokinetics of digoxin in sheep: An example of the utility of student laboratory exercises AU - Riviere, J.E. AU - Dix, L.P. AU - Bai, S.A. AU - Anderson, D.L. T2 - 64th Conference of Research Workers in Animal Diseases C2 - 1983/// C3 - Abstracts of papers presented at the 64th Annual Meeting of the Conference of Research Workers in Animal Disease CY - Chicago, IL DA - 1983/// PY - 1983/11/14/ SP - 15 ER - TY - CONF TI - Physiologic determinants of gentamicin gamma phase pharmacokinetics in the dog. Effects of subtotal surgical nephrectomy and familiar hypothyroidism AU - Riviere, J.E. AU - Carver, M.P. T2 - 64th Conference of Research Workers in Animal Diseases C2 - 1983/// C3 - Abstracts of papers presented at the 64th Annual Meeting of the Conference of Research Workers in Animal Disease CY - Chicago, IL DA - 1983/// PY - 1983/11/14/ SP - 15 ER - TY - JOUR TI - Application of biplot methods to the multivariate analysis of toxicological and pharmacokinetic data. AU - Riviere, J.E. AU - Shy-Modjeska, J.S. AU - Rawlings, J.O. T2 - Pharmacologist DA - 1983/// PY - 1983/// VL - 25 SP - 232 ER - TY - BOOK TI - Veterinary Pharmacology and Therapeutics AU - Riviere, J.E. AU - Booth, N.H. AU - McDonald, L.E. DA - 1983/// PY - 1983/// ET - 5th VL - 182 SE - 402 ER - TY - CONF TI - Effect Of Deer Reduction And Abundance of the Deer Tick AU - Wilson, M.L. AU - Levine, J.F. AU - Spielman, A. T2 - Lyme Disease Symposium C2 - 1983/11// CY - New Haven, Connecticut DA - 1983/11// PY - 1983/11// ER - TY - CONF TI - Vectorial Capacity in Ixodes Ticks AU - Spielman, A. AU - Levine, J.F. AU - Wilson, ML T2 - Lyme Disease Symposium C2 - 1983/11// CY - New Haven, Connecticut DA - 1983/11// PY - 1983/11// ER - TY - JOUR TI - Coding assignments of the RNA genome segments of California serogroup viruses AU - Bishop, D.H. AU - Fuller, F.J. AU - Akashi, H. T2 - Progress in Clinical Biological Research DA - 1983/// PY - 1983/// VL - 123 SP - 107–117 ER - TY - JOUR TI - Bunyavirus gene structure-function relationships and potential for RNA segment reassortment in the vector: La Crosse and snowshoe hare reassortant viruses in mosquitoes AU - Beaty, F.J. AU - Fuller, F. AU - Bishop, D.H. T2 - Progress in Clinical Biological Research DA - 1983/// PY - 1983/// VL - 123 SP - 119–128 ER - TY - CHAP TI - Bunyavirus Gene Structure‐Function Relationships and Potential for RNA Segment Reassortment In The Vector: La Crosse and Snowshoe Hare Reassortant Viruses In Mosquitoes AU - Beaty, B.J. AU - Fuller, F.J. AU - Bishop, D.H.L. T2 - California serogroup viruses : proceedings of an International Symposium, held in Cleveland, Ohio, November 12 and 13, 1982 A2 - Calisher, C.H. A2 - Thompson, W.H. T3 - Progress in clinical and biological research PY - 1983/// SP - 119–128 PB - A.R. Liss SN - 9780845101230 SV - 123 ER - TY - CHAP TI - Coding Assignments of the RNA Genome Segments of California Serogroup Viruses AU - Bishop, D.H.L. AU - Fuller, F.J. AU - Akashi, H. T2 - California serogroup viruses : proceedings of an International Symposium, held in Cleveland, Ohio, November 12 and 13, 1982 A2 - Calisher, C.H. A2 - Thompson, W.H. T3 - Progress in clinical and biological research PY - 1983/// SP - 107–117 PB - A.R. Liss SN - 9780845101230 SV - 123 ER - TY - JOUR TI - Production of cholera toxin-like toxin by Vibrio mimicus and non-0l Vibrio cholerae: Batch culture conditions for optimum yields and isolation of hypertoxigenic lincomycin-resistant mutants AU - Spira, W.M. AU - Fedorka-Cray, P.J. T2 - Infection and Immunity DA - 1983/// PY - 1983/// VL - 42 IS - 2 SP - 501-509 ER - TY - JOUR TI - Enterotoxin production by Vibrio cholerae and Vibrio mimicus grown in continuous culture with microbial cell recycle AU - Spira, W.M. AU - Fedorka-Cray, P.J. T2 - Applied and Environmental Microbiology DA - 1983/// PY - 1983/// VL - 46 IS - 3 SP - 704-709 ER - TY - JOUR TI - Colonization of the rabbit small intestine by clinical and environmental isolates of non-01 Vibrio cholerae and Vibrio mimicus AU - Spira, W.M. AU - Fedorka-Cray, P.J. AU - Pettebone, P. T2 - Infection and Immunity DA - 1983/// PY - 1983/// VL - 41 IS - 3 SP - 1175-1183 ER - TY - JOUR TI - Bunyavirus Nucleoprotein, N, and a Non-structural Protein, NSS, Are Coded by Overlapping Reading Frames in the S RNA AU - Fuller, F. AU - Bhown, A. S. AU - Bishop, D. H. L. T2 - Journal of General Virology AB - SUMMARY It has been shown previously, by sequence analysis of the S RNA segment of snowshoe hare (SSH) bunyavirus, that two overlapping open reading frames in the viral complementary sequence code for proteins with molecular weights of 26.8 × 103 and 10.5 × 103 respectively. In addition to the viral nucleocapsid (N) protein, which is coded by the S RNA, analyses of parental and reassortant bunyavirus-infected cell extracts have shown that the viral S RNA and M RNA species each code for nonstructural proteins (NSS and NSM, respectively). In the present report, in vitro translation analyses of the S mRNA species recovered from virus-infected cells indicate that a single size class of mRNA directs the synthesis of N and NSS. Compositional analyses of selected tryptic peptides of N and NSS have provided proof that N is the product of the first open reading frame, and NSS the product of the second. DA - 1983/8/1/ PY - 1983/8/1/ DO - 10.1099/0022-1317-64-8-1705 VL - 64 IS - 8 SP - 1705-1714 J2 - Journal of General Virology LA - en OP - SN - 0022-1317 1465-2099 UR - http://dx.doi.org/10.1099/0022-1317-64-8-1705 DB - Crossref ER - TY - JOUR TI - Tick-borne viruses structurally similar to orthomyxoviruses AU - Cler, John P.M. AU - Fuller, Frederick AU - Bishop, David H.L. T2 - Virology AB - Members of the Orthomyxoviridae are characterized at the structural level as enveloped, negative sense, RNA viruses that bud from the outer plasma membranes of infected cells and have seven or eight species of single-stranded RNA. None of the three types of orthomyxoviruses (influenza A, B, C) has been shown to be transmitted by arthropods; rather, the viruses are transmitted directly or indirectly from one infected vertebrate to another. Analyses of the virion RNA species and polypeptides of the tick-borne Thogoto and Dhori viruses indicate that they have structural characteristics similar to accepted members of the Orthomyxoviridae. For example, the viruses have seven size classes of single-stranded RNA with 3′ end consensus sequences of HOUCGUUG (or U or A) UUGUUC…. The viruses contain 54–56 × 103 Da nucleocapsid protein, an internal 28 × 103 Da putative matrix protein plus minor 85–90 × 103 Da proteins, and a major outer 65 × 103 Da glycoprotein. In addition to their sensitivity to actinomycin D and α-amanitin the viruses morphologically and morphogenetically resemble orthomyxoviruses. DA - 1983/5// PY - 1983/5// DO - 10.1016/0042-6822(83)90384-7 VL - 127 IS - 1 SP - 205-219 J2 - Virology LA - en OP - SN - 0042-6822 UR - http://dx.doi.org/10.1016/0042-6822(83)90384-7 DB - Crossref ER - TY - JOUR TI - Interference between bunyaviruses in Aedes triseriatus mosquitoes AU - Beaty, Barry J. AU - Bishop, David H.L. AU - Gay, Mary AU - Fuller, Frederick T2 - Virology AB - Inhibition of the replication of alternate California serogroup bunyaviruses in Aedes triseriatus mosquitoes has been observed for mosquitoes previously infected with La Crosse (LAC) virus. By contrast, prior infection of mosquitoes with LAC virus did not interfere significantly with the subsequent infection and replication of Guaroa bunyavirus (Bunyamwera serogroup), or heterologous viruses such as West Nile flavivirus, or vesicular stomatitis rhabdovirus. DA - 1983/5// PY - 1983/5// DO - 10.1016/0042-6822(83)90373-2 VL - 127 IS - 1 SP - 83-90 J2 - Virology LA - en OP - SN - 0042-6822 UR - http://dx.doi.org/10.1016/0042-6822(83)90373-2 DB - Crossref ER - TY - JOUR TI - Peritonitis associated with peritoneal dialysis. Diagnosis and treatment AU - Thornhill, J. A. AU - Riviere, J. E. T2 - Journal of the American Veterinary Medical Association DA - 1983/// PY - 1983/// VL - 182 SP - 721-724 ER - TY - CHAP TI - Toxicology and pharmacology AU - Aronson, A. L. AU - Riviere, J. E. T2 - Feline medicine PY - 1983/// VL - 3 SP - 62-78 PB - Santa Barbara, CA: American Veterinary Publications, Inc. SN - 0939674009 ER - TY - JOUR TI - SPECIES DEPENDENT GENTAMICIN PHARMACOKINETICS AND NEPHROTOXICITY IN THE YOUNG HORSE AU - RIVIERE, JE AU - COPPOC, GL AU - HINSMAN, EJ AU - CARLTON, WW AU - TRAVER, DS T2 - FUNDAMENTAL AND APPLIED TOXICOLOGY AB - Gentamicin pharmacokinetics and nephrotoxic potential were evaluated in twelve 2 to 3 month-old horses. Whereas recent evidence in our clinic indicated that young horses may be especially susceptible to gentamicin nephrotoxicity, young rabbits and rats are usually resistant. Gentamicin (4.5 mg/kg) was given by rapid intravenous injection, Serum gentamicin concentrations over a 13-hour period were fitted to an open, two-compartment, pharmacokinetic model. Subsequently, the same horses were divided into groups of 3 horses each. Each group received 0, 2.2, 4.4 or 8.8 mg gentamicin/kg, intramuscularly, every 12 hours for 15 days. Renal function was monitored. Peak and trough gentamicin concentrations were monitored daily. Renal sections were collected for histopathologic and electron microscopic examination. The (mean ± SD) serum halflife was 194 ± 37 minutes, total body clearance (ClB) was 1.65 ± 0.79 mL/min/kg and volume of distribution at steady state (Vd(ss)) was 30.6 ± 9.4 L/100 kg. Decreased renal function, as detected by elevated serum urea nitrogen or creatinine concentrations, was detected only in the two youngest foals (including animals in both the 4.4 and 8.8 mg/kg dose groups). The trough serum gentamicin concentrations of these 2 horses increased over time. These horses had the lowest ClB and Vd(ss) in the intravenous study. Morphologic changes were seen in kidneys of all treated horses and were similar to those occurring with gentamicin toxicity in other species. Our results support the clinical impression that very young horses may be more susceptible than adult horses, and adults of other species, to gentamicin nephrotoxicity. DA - 1983/// PY - 1983/// DO - 10.1016/S0272-0590(83)80020-7 VL - 3 IS - 5 SP - 448-457 SN - 0272-0590 ER - TY - JOUR TI - MORPHOLOGICAL AND FUNCTIONAL-ASPECTS OF EXPERIMENTAL GENTAMICIN-NEPHROTOXICITY IN YOUNG BEAGLES AND FOALS AU - RIVIERE, JE AU - HINSMAN, EJ AU - COPPOC, GL AU - CARLTON, WW AU - TRAVER, DS T2 - VETERINARY RESEARCH COMMUNICATIONS DA - 1983/// PY - 1983/// DO - 10.1007/BF02228621 VL - 7 IS - 1-4 SP - 211-213 SN - 0165-7380 ER - TY - CHAP TI - Checklist of hazardous drugs in patients with renal failure AU - Riviere, J. E. T2 - Current veterinary therapy VIII: small animal practice PY - 1983/// VL - 8 SP - 1036-1041 PB - Philadelphia: WB Saunders Co. SN - 0721654657 ER - TY - CHAP TI - Adverse drug reactions AU - Aronson, A. L. AU - Riviere, J. E. T2 - Current veterinary therapy VIII: small animal practice PY - 1983/// VL - 8 SP - 122-128 PB - Philadelphia: WB Saunders Co. SN - 0721654657 ER -