Works Published in 2019

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Displaying works 181 - 200 of 227 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 review

Language Consideration and Methodological Transparency in "Systematic" Reviews of Animal Toxicity Studies

[Review of ]. INTERNATIONAL JOURNAL OF TOXICOLOGY, 38(2), 135–145.

By: K. Alpi n, T. Vo n & D. Dorman n

author keywords: toxicology; translation; foreign languages; publications; systematic review methodology; authorship
MeSH headings : Animals; Authorship; Language; Meta-Analysis as Topic; Research Design; Research Support as Topic; Systematic Reviews as Topic; Toxicity Tests
TL;DR: Neither the study type, grant funding, nor first author country of affiliation was associated with an increased consideration of NEL, and study quality reporting was more common in SRs that considered multiple languages. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 22, 2019

2019 journal article

Development and application of a population physiologically based pharmacokinetic model for florfenicol and its metabolite florfenicol amine in cattle

FOOD AND CHEMICAL TOXICOLOGY, 126, 285–294.

author keywords: Physiologically based pharmacokinetic (PBPK) model; Withdrawal interval; Florfenicol; Florfenicol amine; Cattle
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / analysis; Anti-Bacterial Agents / metabolism; Anti-Bacterial Agents / pharmacokinetics; Cattle; Cattle Diseases / drug therapy; China; Chromatography, High Pressure Liquid; Drug Administration Routes; Drug Residues / analysis; Drug Residues / metabolism; Drug Residues / pharmacokinetics; Kidney / drug effects; Liver / drug effects; Models, Biological; Thiamphenicol / administration & dosage; Thiamphenicol / analogs & derivatives; Thiamphenicol / analysis; Thiamphenicol / metabolism; Thiamphenicol / pharmacokinetics
TL;DR: A population physiologically based pharmacokinetic (PBPK) model to predict the concentrations of FF and its metabolite, florfenicol amine, in cattle after four different routes of administration, and to calculate and compare the withdrawal intervals (WDIs) with approved withdrawal times based on different marker residues and their MRLs or tolerances. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Seroprevalence, risk factors and spatial distribution of West Nile virus in Jordan

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 113(1), 24–30.

author keywords: emerging; infectious diseases; Middle East; virus; West Nile virus; zoonotic
MeSH headings : Adolescent; Adult; Aged; Aged, 80 and over; Antibodies, Viral / blood; Child; Climate; Cross-Sectional Studies; Drinking Water; Female; Humans; Immunoglobulin G / blood; Jordan / epidemiology; Male; Middle Aged; Risk Factors; Seroepidemiologic Studies; Socioeconomic Factors; Spatial Analysis; Surveys and Questionnaires; West Nile Fever / blood; West Nile Fever / epidemiology; West Nile Fever / etiology; West Nile Fever / virology; West Nile virus / growth & development; Young Adult
TL;DR: It is demonstrated that WNV is circulating in Jordan and should be considered as a differential diagnosis in medical cases presenting with nervous system symptoms, especially for older populations living in the Jordan Valley and Badia areas. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Comparative Pathology of Hepatitis A Virus and Hepatitis E Virus Infection

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE, 9(4).

MeSH headings : Animals; Disease Models, Animal; Hepatitis A / pathology; Hepatitis A / virology; Hepatitis A virus; Hepatitis E / pathology; Hepatitis E / virology; Hepatitis E virus; Humans; Liver / pathology; Phylogeny; Primates
TL;DR: In general, animals infected with these viruses recapitulate the histologic lesions seen in infected humans, but typically with less severe clinical and histopathological manifestations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Transmission on empirical dynamic contact networks is influenced by data processing decisions

EPIDEMICS, 26, 32–42.

By: D. Dawson n, T. Farthing n, M. Sanderson* & C. Lanzas n

author keywords: Dynamic contact data; Data processing; Entropy; Contact networks; Transmission dynamics; Disease transmission model
MeSH headings : Animals; Cattle; Cattle Diseases / epidemiology; Cattle Diseases / transmission; Epidemics / statistics & numerical data; Epidemics / veterinary; Models, Statistical
TL;DR: It is found that changes made to information content by processing decisions translated to significant impacts to the transmission dynamics of disease models using the contact data, and that SpTh had the largest independent influence on information content. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: April 15, 2019

2019 journal article

Multi-locus DNA sequence analysis, antifungal agent susceptibility, and fungal keratitis outcome in horses from Southeastern United States

PLOS ONE, 14(3).

By: M. Cullen n, M. Jacob n, V. Cornish n, I. VanderSchel n, H. Cotter n, M. Cubeta n, I. Carbone n, B. Gilger n

MeSH headings : Animals; Antifungal Agents / pharmacology; Eye Infections, Fungal / drug therapy; Eye Infections, Fungal / microbiology; Eye Infections, Fungal / veterinary; Horse Diseases / drug therapy; Horse Diseases / microbiology; Horses; Keratitis / drug therapy; Keratitis / microbiology; Keratitis / veterinary; Southeastern United States; Species Specificity; Thiabendazole / pharmacology
TL;DR: The results of this study suggest that treatment of equine FK with antifungal agents requires accurate fungal species identification, and demonstrate the importance of fungal identification to the species rather than genus level. (via Semantic Scholar)
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Dietary amino acids under hypoxic conditions exacerbates muscle myopathies including wooden breast and white stripping

POULTRY SCIENCE, 98(3), 1517–1527.

author keywords: glutamine; arginine; woody breast; white striping; broilers
MeSH headings : Amino Acids; Animal Feed / analysis; Animal Nutritional Physiological Phenomena; Animals; Chickens / growth & development; Chickens / physiology; Diet / veterinary; Hypoxia / pathology; Meat / analysis; Muscular Diseases / etiology; Muscular Diseases / pathology; Muscular Diseases / veterinary; Pectoralis Muscles / pathology; Poultry Diseases / etiology; Poultry Diseases / pathology
TL;DR: Results indicated that increased muscle Ca is associated with increased WB, while increased dietary glutamine and lack of oxygen may have resulted in a reverse flux of the citric acid cycle and reduced electron transport chain activity resulting in increased WS. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Bile salt hydrolases: Gatekeepers of bile acid metabolism and host-microbiome crosstalk in the gastrointestinal tract

PLOS PATHOGENS, 15(3).

MeSH headings : Amidohydrolases / metabolism; Amidohydrolases / physiology; Bile Acids and Salts / metabolism; Gastrointestinal Microbiome / physiology; Gastrointestinal Tract; Host Microbial Interactions / physiology; Humans
TL;DR: Bile acids serve as substrates for bile acid receptors (BARs) found throughout the body that control critical regulatory and metabolic processes and therefore represent an important class of bioactive molecules, and there remain gaps in knowledge about the bacterial enzymes driving their composition and modification. (via Semantic Scholar)
Source: Web Of Science
Added: April 15, 2019

2019 journal article

Alternative reproductive adaptations predict asymmetric responses to climate change in lizards

SCIENTIFIC REPORTS, 9.

MeSH headings : Adaptation, Physiological / physiology; Animals; Biodiversity; Body Temperature; Climate Change; Cold Climate; Lizards
TL;DR: These analyses support the ‘cul-de-sac hypothesis’s fundamental prediction that elevational shifts are more severe in viviparous species, and highlight the role that life-history adaptations play in the responses of biodiversity to ongoing climate change. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science; OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: April 9, 2019

2019 journal article

The Behavioral Economics of Alcohol Demand in French and American University Students

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 43(3), 531–544.

By: M. Martinetti*, R. Caughron*, H. Berman n, J. Andre*, M. Sokolowski*, S. Wiley*, M. Naassila*

author keywords: Behavioral Economics; Alcohol Demand; Cross-Cultural Research; Hypothetical Purchase Task; Essential Value
MeSH headings : Adult; Alcohol Drinking / economics; Alcohol Drinking / psychology; Choice Behavior; Commerce / economics; Consumer Behavior / statistics & numerical data; Female; France; Humans; Male; Motivation; Students / psychology; Surveys and Questionnaires / statistics & numerical data; United States; Universities; Young Adult
TL;DR: Low-cost alcohol is associated with increased alcohol consumption in both French and U.S. university students, and concurrent availability of a nonalcoholic beverage within the APT both reduces alcohol demand and demonstrates behavioral economic substitutability. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 2, 2019

2019 article

Pathology in Practice

Pfisterer, B. R., Corps, K. N., & Jennings, S. H. (2019, March 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 254, pp. 681–683.

By: B. Pfisterer, K. Corps & S. Jennings*

MeSH headings : Animals; Clostridium Infections / pathology; Clostridium Infections / veterinary; Foreign Bodies / veterinary; Horse Diseases / pathology; Horses; Male; Wound Infection / microbiology; Wound Infection / pathology; Wound Infection / veterinary
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 2, 2019

2019 article

Tracing foot-and-mouth disease virus phylogeographical patterns and transmission dynamics

Jara, M., Frias-De-Diego, A., Dellicour, S., Baele, G., & Machado, G. (2019, March 28). BioRxiv, Vol. 3.

TL;DR: This study provides significant insights into the spatiotemporal dynamics of the global circulation of FMDV serotypes, by characterizing the viral routes of spread at serotype level, especially uncovering the importance of host species for each serotype in the evolution and spread of F MDV which further improve future decisions for more efficient control and eradication. (via Semantic Scholar)
Source: ORCID
Added: March 29, 2019

2019 journal article

Expression of T-Bet, Eomesodermin, and GATA-3 Correlates With Distinct Phenotypes and Functional Properties in Porcine gamma delta T Cells

FRONTIERS IN IMMUNOLOGY, 10.

By: I. Rodriguez-Gomez*, S. Talker*, T. Kaeser, M. Stadler*, L. Reiter*, A. Ladinig*, J. Milburn*, S. Hammer* ...

author keywords: gamma delta T cells; swine; pig; T-bet; Eomes; GATA-3
MeSH headings : Animals; GATA3 Transcription Factor / biosynthesis; GATA3 Transcription Factor / immunology; Phenotype; Receptors, Antigen, T-Cell, gamma-delta / immunology; Swine / immunology; T-Box Domain Proteins / biosynthesis; T-Box Domain Proteins / immunology; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / metabolism
TL;DR: A role for GATA-3 is suggested in the development of γδ-thymocytes and in the function of peripheral CD2−CD8α−/dimCD27+perforin− γ´ T cells and the unique phenotype of these porcine T cells suggests that they represent a thymus-derived separate lineage in the pig. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: March 25, 2019

2019 journal article

Isobaric Labeling Quantitative Metaproteomics for the Study of Gut Microbiome Response to Arsenic

JOURNAL OF PROTEOME RESEARCH, 18(3), 970–981.

author keywords: metaproteomics; gut microbiome; arsenic; isobaric labeling; tandem mass tags; label free; MetaPro-IQ
MeSH headings : Arsenic / pharmacology; Feces / microbiology; Gastrointestinal Microbiome / drug effects; Gastrointestinal Microbiome / genetics; Humans; Proteome / analysis; Proteome / drug effects; Proteomics / methods; Proteomics / standards; RNA, Ribosomal, 16S / analysis
TL;DR: A new experimental workflow coupled to isobaric labeling and MetaPro-IQ was demonstrated for the metaproteomics study of arsenic-induced gut microbiome perturbations, demonstrating the significant improvement of quantitative metAProteomics for gut microbiome study. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 25, 2019

2019 journal article

Serum Metabolomics Reveals That Gut Microbiome Perturbation Mediates Metabolic Disruption Induced by Arsenic Exposure in Mice

JOURNAL OF PROTEOME RESEARCH, 18(3), 1006–1018.

author keywords: arsenic; metabolomics; mouse model; bacterial infection; gut microbiome
MeSH headings : Animals; Arsenic / pharmacology; Bacterial Infections / complications; Gastrointestinal Microbiome / physiology; Mass Spectrometry; Metabolic Diseases / etiology; Metabolome / drug effects; Metabolomics / methods; Mice; Serum / metabolism
TL;DR: It is suggested that gut microbiome perturbation can exacerbate or cause metabolic disorders induced by arsenic exposure, including fatty acid metabolism, phospholipids, sphingolIPids, cholesterols, and tryptophan metabolism. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 25, 2019

2019 journal article

Quantitative proteomics reveals systematic dysregulations of liver protein metabolism in sucralose-treated mice

JOURNAL OF PROTEOMICS, 196, 1–10.

author keywords: Artificial sweetener; Sucralose; Liver proteome; Tandem mass tags; Quantitative proteomics
MeSH headings : Animals; Gastrointestinal Microbiome / drug effects; Liver / metabolism; Male; Mice; Proteome / metabolism; Proteomics; Sucrose / analogs & derivatives; Sucrose / pharmacology
TL;DR: The first quantitative proteomics for mice liver proteome was demonstrated, proposed that enhanced inflammation may be triggered by ribosomal inactivation in sucralose treated mice liver, and revealed the systematic dysregulations of protein metabolism after Sucralose treatment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: March 25, 2019

2019 journal article

Genotypic and Phenotypic Variables Affect Meiotic Cell Cycle Progression, Tumor Ploidy, and Cancer-Associated Mortality in a brca2-Mutant Zebrafish Model

JOURNAL OF ONCOLOGY, 2019.

TL;DR: It is determined that combined brca2/tp53 mutations uniquely disrupt meiotic progression and that sex significantly influences ploidy outcome in zebrafish cancers, and evidence is provided to support a link between BRCA2 mutation, tumor diploidy, and poor survival outcome. (via Semantic Scholar)
Source: Web Of Science
Added: March 25, 2019

2019 journal article

Endothelial alterations in a canine model of immune thrombocytopenia

PLATELETS, 30(1), 88–97.

By: D. LeVine n, R. Cianciolo*, K. Linder n, P. Bizikova n, A. Birkenheuer n, M. Brooks*, A. Salous*, S. Nordone n ...

author keywords: Dog; endothelium; ITP
MeSH headings : Animals; Biomarkers; Biopsy; Blood Coagulation; Blood Platelets / metabolism; Blood Platelets / ultrastructure; Disease Models, Animal; Dogs; Endothelium / metabolism; Endothelium / ultrastructure; Flow Cytometry; Lysophospholipids / blood; Male; Platelet Activation; Platelet Count; Purpura, Thrombocytopenic, Idiopathic / blood; Purpura, Thrombocytopenic, Idiopathic / drug therapy; Purpura, Thrombocytopenic, Idiopathic / etiology; Purpura, Thrombocytopenic, Idiopathic / metabolism; Sphingosine / analogs & derivatives; Sphingosine / blood; von Willebrand Factor / metabolism
TL;DR: The results indicate that endothelial damage occurs in the canine ITP model and variability in the degree of endothelialDamage may account for differences in the bleeding phenotype among patients with ITP. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 18, 2019

2019 journal article

Cellular Innate Immunity against PRRSV and Swine Influenza Viruses

Veterinary Sciences, 6(1), 26.

author keywords: pig; innate immunity; PRRSV; swine influenza virus
TL;DR: This review focuses on the interactions of two enveloped RNA viruses—porcine reproductive and respiratory syndrome virus (PRRSV) and swine influenza virus (SwIV)—as major etiological agents that contribute to PRDC within the porcine cellular innate immunity during infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: ORCID, Crossref
Added: March 16, 2019

2019 journal article

Multiomics modeling of the immunome, transcriptome, microbiome, proteome and metabolome adaptations during human pregnancy

BIOINFORMATICS, 35(1), 95–103.

By: M. Ghaemi*, D. DiGiulio*, K. Contrepois*, B. Callahan n, T. Ngo*, B. Lee-McMullen*, B. Lehallier*, A. Robaczewska* ...

Ed(s): J. Wren

MeSH headings : Computational Biology; Female; Humans; Metabolome; Microbiota; Pregnancy; Proteome; Transcriptome
TL;DR: This model not only significantly increased predictive power by combining all datasets, but also revealed novel interactions between different biological modalities, which provides the frameworks for future studies examining deviations implicated in pregnancy‐related pathologies including preterm birth and preeclampsia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Sources: Web Of Science, ORCID
Added: March 11, 2019

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