Works Published in 2016

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Displaying works 41 - 60 of 221 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 journal article

Mechanistic Toxicity Assessment of Hexahydroisohumulone in Canine Hepatocytes, Renal Proximal Tubules, Bone Marrow-Derived Mesenchymal Stem Cells, and Enterocyte-like Cells

International Journal of Veterinary Health Science & Research, 4(2), 88–103.

By: K. Choi, J. Koci, M. Ortega, B. Jeffery, J. Riviere* & N. Monteiro Riviere

TL;DR: Investigating organ-specific oxidative stress and the molecular mechanism of toxicity using the pathway-focused DNA array of the hop ingredient hexahydroisohumulone with canine hepatocytes, canine proximal tubule cells, bone marrow-derived mesenchymal stem cells and enterocyte-like cells provides insight into genes altered with HEX exposure and the cell-type specific responses in dogs. (via Semantic Scholar)
Source: Crossref
Added: October 1, 2021

2016 journal article

A computational framework for interspecies pharmacokinetics, exposure and toxicity assessment of gold nanoparticles

Nanomedicine, 11(2), 107–119.

author keywords: biodistribution; computational nanotoxicology; endocytosis; nanomaterials; PBPK modeling; physiologically based pharmacokinetic modeling; phagocytosis; toxicokinetics
MeSH headings : Animals; Cell Survival / drug effects; Computer Simulation; Dose-Response Relationship, Drug; Environmental Exposure / adverse effects; Gold / pharmacokinetics; Gold / toxicity; Humans; Metabolic Clearance Rate; Mice; Models, Biological; Nanoparticles / toxicity; Rats; Species Specificity; Swine; Tissue Distribution; Toxicity Tests / methods
TL;DR: These results partially explain the current low translation rate of nanotechnology-based drug delivery systems from mice to humans and may be applied to other nanomaterials and provides guidance to design future translational studies. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: October 1, 2021

2016 journal article

Biological and environmental surface interactions of nanomaterials: characterization, modeling, and prediction

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, 9(3), e1440.

MeSH headings : Animals; Biocompatible Materials; Biomedical Research; Humans; Mice; Models, Theoretical; Molecular Dynamics Simulation; Nanostructures; Structure-Activity Relationship; Surface Properties
TL;DR: To quantitatively decipher these physicochemical surface interactions, computational methods can be used for either analyses of large amounts of experimental characterization data, or theoretical prediction of the interactions, and consequent biological behavior in the body after administration. (via Semantic Scholar)
Source: Crossref
Added: September 30, 2021

2016 journal article

Protein corona modulation of hepatocyte uptake and molecular mechanisms of gold nanoparticle toxicity

Nanotoxicology, 11(1), 64–75.

author keywords: Gold nanoparticles; human hepatocytes; cell uptake; cytochrome P450; mechanisms of action
MeSH headings : Albumins / chemistry; Blood Proteins / chemistry; Cell Survival / drug effects; Dose-Response Relationship, Drug; Gene Expression Profiling; Gold / chemistry; Gold / metabolism; Gold / toxicity; Hepatocytes / drug effects; Hepatocytes / metabolism; Humans; Metal Nanoparticles / chemistry; Metal Nanoparticles / toxicity; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / metabolism; Reactive Oxygen Species / metabolism; Transcriptome / drug effects
TL;DR: Human hepatic uptake of 40 and 80 nm AuNP with branched polyethylenimine (BPEI), lipoic acid (LA) and polyethylene glycol (PEG) coatings as well as human plasma protein (HP) and human serum albumin (HSA) coronas was investigated to better understanding of the dramatic effect of protein coronas (PC) on AuNP cellular uptake, cytotoxicity and their underlying molecular mechanisms of action. (via Semantic Scholar)
Source: Crossref
Added: September 30, 2021

2016 journal article

Endocrine active contaminants in aquatic systems and intersex in common sport fishes

Environmental Toxicology and Chemistry, 36(4), 959–968.

By: C. Lee Pow n, J. Law n, T. Kwak n, W. Cope n, J. Rice n, S. Kullman n, D. Aday n

author keywords: Intersex; Estrogens; Endocrine disruption; Black bass; Sunfish
MeSH headings : Animals; Bass / growth & development; Bass / metabolism; Disorders of Sex Development / chemically induced; Endocrine Disruptors / analysis; Endocrine Disruptors / toxicity; Endocrine System / drug effects; Environmental Monitoring; Female; Male; North Carolina; Oocytes / drug effects; Oocytes / growth & development; Rivers / chemistry; Seasons; Species Specificity; Sports; Testis / drug effects; Testis / growth & development; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
TL;DR: The authors’ results associate genus‐specific prevalence of intersex with specific EAC classes in common sport fishes having biological, ecological, and conservation implications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Crossref
Added: January 21, 2021

2016 journal article

Systemic Lupus Erythematosus-A Review

Clinician’s Brief.

By: G. Aitee & K. Harrell

Source: NC State University Libraries
Added: December 23, 2020

2016 journal article

Characterization of Common Horse Feeds in Selected Areas of Ethiopia

Global Journal of Science Frontier Research: D Agriculture and Veterinary, 16(3), 37–42.

By: E. Muleta, A. Mengistu, D. Geleti, N. Aklilu & G. Asebe

Source: NC State University Libraries
Added: October 23, 2020

2016 chapter

Marek’s disease.

In S. Williams (Ed.), A laboratory manual for the isolation, identification and characterization of avian pathogens (6th ed.). Jacksonville, FL: American Association of Avian Pathologists.

By: I. Gimeno & P. Walkenell

Ed(s): S. Williams

Source: NC State University Libraries
Added: October 21, 2020

2016 journal article

Health concerns and management of select veterinary drug residues

Food and Chemical Toxicology, 88, 112–122.

By: R. Baynes n, K. Dedonder*, L. Kissell n, D. Mzyk n, T. Marmulak*, G. Smith n, L. Tell*, R. Gehring*, J. Davis n, J. Riviere*

author keywords: Drug; Veterinary; Residue; Adverse; Livestock
MeSH headings : Animals; Carcinogens; Drug Residues / adverse effects; Humans; Veterinary Drugs / chemistry; Veterinary Drugs / metabolism; Veterinary Drugs / pharmacokinetics
TL;DR: The aim of this manuscript is to review the potential adverse health effects in humans if exposed to residues of selected veterinary drugs used in food-producing animals and how regulatory and independent organizations manage the risk of these veterinary drugs based on data from human health risk assessments. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 24, 2020

2016 journal article

Unraveling the causes of respiratory disease in the working equids of Ethiopia: A cross sectional survey

Journal of Equine Veterinary Science, 39, S98.

By: G. Laing*, R. Christley*, A. Stringer*, A. Radford*, N. Aklilu, R. Newton*, G. Pinchbeck*

TL;DR: Clinical signs of respiratory disease were relatively uncommon on examination of these working horses; however owners reported higher levels of respiratory signs in the previous 30 days, particularly coughing, consistent with results from the previous participatory studies. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 10, 2020

2016 journal article

Pharmacokinetics of 14 C-ortho-phenylphenol following intravenous administration in pigs.

Journal of Applied Toxicology : JAT.

Emma Nixon

author keywords: pharmacokinetics; ortho-phenylphenol; intravenous dose; pig; biocide
MeSH headings : Administration, Intravenous; Animals; Area Under Curve; Biphenyl Compounds / administration & dosage; Biphenyl Compounds / pharmacokinetics; Disinfectants / pharmacokinetics; Feces / chemistry; Half-Life; Male; Sus scrofa; Swine; Tissue Distribution
TL;DR: Comparisons with other species suggest that 14C‐OPP clearance in pigs (2.48 ml h–1 kg–1) is less than that in humans and rats and that the kidneys play a crucial role in clearance with a large percentage of the dose being found in the urine. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: February 5, 2020

2016 journal article

Development and Evaluation of a Molecular Diagnostic Method for Rapid Detection of Histoplasma capsulatum var. farciminosum, the Causative Agent of Epizootic Lymphangitis, in Equine Clinical Samples

Journal of Clinical Microbiology, 54(12), 2990–2999.

By: C. Scantlebury*, G. Pinchbeck*, P. Loughnane*, N. Aklilu*, T. Ashine*, A. Stringer, L. Gordon*, M. Marshall*, R. Christley*, A. McCarthy*

Contributors: C. Scantlebury*, G. Pinchbeck*, P. Loughnane*, N. Aklilu*, T. Ashine*, A. Stringer, L. Gordo*, M. Marshall*, R. Christley*, A. McCarthy*

Ed(s): B. Fenwick

MeSH headings : Animals; Blood / microbiology; Corynebacterium pseudotuberculosis / isolation & purification; DNA, Ribosomal Spacer / genetics; Diagnosis, Differential; Ethiopia; Histoplasma / classification; Histoplasma / isolation & purification; Histoplasmosis / diagnosis; Histoplasmosis / microbiology; Histoplasmosis / veterinary; Horse Diseases / diagnosis; Horse Diseases / microbiology; Horses; Lymphangitis / diagnosis; Lymphangitis / microbiology; Lymphangitis / veterinary; Molecular Diagnostic Techniques / methods; Polymerase Chain Reaction / methods; Suppuration / microbiology
TL;DR: A nested PCR method targeting the internal transcribed spacer (ITS) region of the rRNA operon was validated for application to equine clinical samples and outperformed conventional microscopic diagnosis of EZL in equine blood and at high frequency among horses exhibiting cutaneous lesions. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 5, 2020

2016 journal article

Circulating serovars of Leptospira in cart horses of central and southern Ethiopia and associated risk factors

Preventive Veterinary Medicine, 125, 106–115.

By: K. Tsegay*, A. Potts*, N. Aklilu*, C. Lötter* & B. Gummow*

Contributors: K. Tsegay*, A. Potts*, N. Aklilu*, C. Lötter* & B. Gummow*

author keywords: Ethiopia; Cart horse; Leptospira; Leptospirosis; Seroprevalence; Serovar Bratislava; Risk factors
MeSH headings : Agglutination Tests / veterinary; Animals; Antibodies, Bacterial / blood; Ethiopia / epidemiology; Horse Diseases / epidemiology; Horse Diseases / microbiology; Horses; Leptospira / genetics; Leptospirosis / epidemiology; Leptospirosis / microbiology; Leptospirosis / veterinary; Male; Prevalence; Risk Factors; Seroepidemiologic Studies; Serogroup
TL;DR: The high seroprevalence confirm that leptospirosis is endemic among horses of Central and Southern Ethiopia and supports the idea that serovar Bratislava may be adapted to and maintained by the horse population of Centraland Southern Ethiopia. (via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: February 5, 2020

2016 journal article

Influence of subclinical infection by agents of tick fever in dairy cows on milk production

Revista MVZ Córdoba, 21, 5490–5499.

By: R. Pazinato, G. Machado, L. Stefani & A. Da Silva

Source: NC State University Libraries
Added: November 16, 2019

2016 journal article

Gastrointestinal parasites in dairy cows present in farm show in western Santa Catarina, Brazil

Acta Veterinaria Brasilica, 10(4), 373–377.

By: N. Solda*, A. Da Silva*, P. Glombowsky*, M. Chiocca*, D. Cucco*, T. Oliveira*, G. Machado*

TL;DR: Cattle present in farm show, despite the required sanitary control and in some cases even with previous treatment, have infection gastrointestinal parasites. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: November 16, 2019

2016 chapter

Viral encephalitides in poultry

In The Merck Veterinary Manual (11th ed., pp. 301–303). Whitehouse Station, NJ: Merck and Company, Inc.

By: J. Guy

Source: NC State University Libraries
Added: November 16, 2019

2016 chapter

Turkey coronavirus

In Isolation, Identification, and Characterization of Avian Pathogens (6th ed., pp. 309–312). Athens, GA: American Association of Avian Pathologists.

By: M. Jackwood & J. Guy

Source: NC State University Libraries
Added: November 16, 2019

2016 conference paper

Assessment of the serological response induced by fowlpox virus vector

Proceedings of 65th Western Poultry Disease Conference. Presented at the Vancouver, British Columbia, Canada.

By: F. Lozano, J. Guy, M. West, J. Elattrache, M. Paniago, C. Cazaban, Y. Gardin

Event: at Vancouver, British Columbia, Canada on April 24-27, 2016

Source: NC State University Libraries
Added: November 16, 2019

2016 conference paper

Protective immunity against laryngotracheitis (LT) is enhanced by concurrent vaccination with both herpesvirus of turkeys-vectored LT vaccine and fowl poxvirus-vectored LT vaccine (HVT-LT + FPV-LT)

Proceedings of 65th Western Poultry Disease Conference.

By: J. Guy

Source: NC State University Libraries
Added: November 16, 2019

2016 conference paper

Specific antibody responses to laryngotracheitis (LT) virus and fowl poxvirus (FPV) after vaccination with herpesvirus of turkeys- and FPV-vectored vaccines

Proceedings of 11th International Conference on Marek’s disease virus and avian herpesviruses. Tours, France.

By: J. Guy & M. Byrd

Source: NC State University Libraries
Added: November 16, 2019

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