Works Published in 2018
Displaying works 41 - 60 of 237 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 chapter
Dermatopharmacology: Drugs Acting Locally on the Skin
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 1278–1301). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Aminoglycoside Antibiotics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 877–902). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Tetracycline Antibiotics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 858–876). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Antiarrhythmic Agents
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 537–552). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Pharmacokinetics
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 41–64). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Absorption, Distribution, Metabolism, and Elimination
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 8–40). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 chapter
Veterinary Pharmacology: An Introduction to the Discipline
In J. E. Riviere & M. G. Papich (Eds.), Veterinary Pharmacology and Therapeutics (10th ed., pp. 3–7). Ames, Iowa: Wiley-Blackwell.
Ed(s): J. Riviere & M. Papich
Source: NC State University Libraries
Added: August 13, 2021
2018 journal article
Variation in fluoroquinolone pharmacodynamic parameter values among isolates of two bacterial pathogens of bovine respiratory disease
Scientific Reports, 8(1).
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bovine Respiratory Disease Complex / drug therapy; Bovine Respiratory Disease Complex / microbiology; Cattle; Fluoroquinolones / pharmacology; Fluoroquinolones / therapeutic use; Mannheimia haemolytica / drug effects; Mannheimia haemolytica / genetics; Mannheimia haemolytica / isolation & purification; Microbial Sensitivity Tests; Models, Biological; Pasteurella multocida / drug effects; Pasteurella multocida / genetics; Pasteurella multocida / isolation & purification; Phenotype
TL;DR:
Investigating the fluoroquinolone enrofloxacin PD against different isolates of two bovine respiratory disease pathogens found variability in the PD parameters Hill-coefficient and Emax may impact the strain’s properties such as growth potential, which can have clinical implications.
(via Semantic Scholar)
www.nature.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 13, 2021
2018 journal article
Mathematical modeling and simulation in animal health. Part III: Using nonlinear mixed-effects to characterize and quantify variability in drug pharmacokinetics
Journal of Veterinary Pharmacology and Therapeutics, 41(2), 171–183.
author keywords: covariates; nonlinear mixed effects; population pharmacokinetics; sparse sampling; veterinary medicine
MeSH headings : Animal Diseases / drug therapy; Animals; Models, Theoretical; Nonlinear Dynamics; Pharmacokinetics
TL;DR:
Nonlinear mixed effects (NLME) have been purposely designed to characterize the sources of variability in drug disposition and response and can be used to explore the impact of population-associated variables on the relationship between drug administration, systemic exposure, and the levels of drug residues in tissues.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 13, 2021
2018 journal article
Probabilistic risk assessment of gold nanoparticles after intravenous administration by integrating in vitro and in vivo toxicity with physiologically based pharmacokinetic modeling
Nanotoxicology, 12(5), 453–469.
author keywords: Gold nanoparticle; computational nanotoxicology; physiologically based pharmacokinetic modeling; probabilistic risk assessment
MeSH headings : Administration, Intravenous; Animals; Bayes Theorem; Gold / administration & dosage; Gold / pharmacokinetics; Gold / toxicity; Humans; Metal Nanoparticles / toxicity; Models, Biological; Monte Carlo Method; Risk Assessment
TL;DR:
The results suggest that under the highest dosing level employed in existing animal studies (worst-case scenario), AuNPs coated with branched polyethylenimine (BPEI) would likely induce ∼90–100% cellular death, implying high cytotoxicity compared to <10% cell death induced by low-to-medium animal dosing levels, which are commonly used in animal studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 13, 2021
2018 journal article
Probabilistic Physiologically Based Pharmacokinetic Model for Penicillin G in Milk From Dairy Cows Following Intramammary or Intramuscular Administrations
Toxicological Sciences, 164(1), 85–100.
author keywords: PBPK modeling; dairy cows; food safety; drug residue; Food Animal Residue Avoidance Databank (FARAD); penicillin
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / pharmacokinetics; Cattle; Drug Residues / analysis; Female; Food Contamination / analysis; Injections, Intramuscular; Mammary Glands, Animal / metabolism; Meat / analysis; Milk / chemistry; Models, Biological; Penicillin G / administration & dosage; Penicillin G / pharmacokinetics
TL;DR:
The current PBPK model can help predict milk discard interval for penicillin following extralabel use through IM and IMM administrations and showed that even 4 times label dose did not lead to violative tissue residues in healthy dairy cows with IMM infusions.
(via Semantic Scholar)
Source: Crossref
Added: August 13, 2021
2018 journal article
Modeling gold nanoparticle biodistribution after arterial infusion into perfused tissue: effects of surface coating, size and protein corona
Nanotoxicology, 12(10), 1093–1112.
author keywords: Biodistribution; gold nanoparticles; cell uptake; skin; pharmacokinetics; nanoparticle vascular distribution
MeSH headings : Animals; Epigastric Arteries; Female; Free Tissue Flaps; Gold / administration & dosage; Gold / chemistry; Gold / pharmacokinetics; Humans; Infusions, Intra-Arterial; Metal Nanoparticles / administration & dosage; Metal Nanoparticles / chemistry; Models, Biological; Nanomedicine; Particle Size; Perfusion; Polyethylene Glycols / chemistry; Polyethyleneimine / chemistry; Protein Corona / chemistry; Skin / blood supply; Skin / metabolism; Surface Properties; Swine; Thioctic Acid / chemistry; Tissue Distribution
TL;DR:
These studies paralleled previous in vitro cell culture studies using the same AuNP in human endothelial and renal proximal tubule cells, hepatocytes, keratinocytes, showing BPEI-AuNP having the greatest uptake, although the presence of a PPC did not reduce IPPSF biodistribution as in the cellculture studies.
(via Semantic Scholar)
Source: Crossref
Added: August 13, 2021
2018 report
Magnesium picolinate compositions and methods of use
(US Patent No. US20180098976).
Source: NC State University Libraries
Added: July 28, 2021
2018 report
Magnesium biotinate compositions and methods of use
(U.S. Patent No. 20180071264).
Source: NC State University Libraries
Added: July 28, 2021
2018 speech
Improving Growth and Survival of In Vitro Propagated Mussels and In Vitro Propagation of the Dwarf Wedge Mussel
Presented at the NC Chapter of the American Fisheries Society, Morganton, NC.
Event: NC Chapter of the American Fisheries Society at Morganton, NC
Source: NC State University Libraries
Added: April 26, 2021
2018 report
Freshwater Bivalve Survey
US Army Corps of Engineers/US Army Endangered Species Branch.
Source: NC State University Libraries
Added: April 24, 2021
2018 report
Fish Passage on the Broad River: An Assessment of Freshwater Mussel Distribution after Nine Years of Fish Passage Operation
Broad River Fisheries Mitigation Trust Fund.
Source: NC State University Libraries
Added: April 24, 2021
2018 journal article
Mast Cells Play a Protective Role in Spontaneous Colitis
Journal of Immunology, 200(Supplement 1).
Event: Immunology 2018 at Austin, TX on May 4-8, 2018
Source: NC State University Libraries
Added: April 8, 2021
2018 chapter
Modeling the Argasid Tick (Ornithodoros moubata) Life Cycle
In Association for Women in Mathematics Series (Vol. 14, pp. 63–87).
Contributors: S. Clifton *, C. Davis *, S. Erwin n , G. Hamerlinck*, A. Veprauskas *, Y. Wang *, W. Zhang *, H. Gaff *
TL;DR:
The first mathematical models for an argasid tick are developed to explore the dynamics and identify knowledge gaps of these poorly studied ticks, and provide the basis for developing future models that include disease states to explore infection dynamics and possible management of ASF.
(via Semantic Scholar)
Source: ORCID
Added: January 14, 2021
2018 journal article
Photo-triggered release of 5-fluorouracil from a MOF drug delivery vehicle
Chemical Communications, 54(55), 7617–7620.
MeSH headings : Adsorption; Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Azo Compounds / chemistry; Azo Compounds / radiation effects; Azo Compounds / toxicity; Blood Proteins / chemistry; Cattle; Drug Carriers / chemistry; Drug Carriers / radiation effects; Drug Carriers / toxicity; Fluorouracil / chemistry; Fluorouracil / pharmacology; Humans; MCF-7 Cells; Metal-Organic Frameworks / chemistry; Metal-Organic Frameworks / radiation effects; Metal-Organic Frameworks / toxicity; Mice; Nanoparticles / chemistry; Nanoparticles / radiation effects; Nanoparticles / toxicity; Particle Size; Polyethylene Glycols / chemistry; Polyethylene Glycols / toxicity; Porosity; Ultraviolet Rays
TL;DR:
A nano metal-organic-framework (nanoMOF) was employed as a first-of-its kind drug delivery vehicle (DDV) for the photo-controlled release of therapeutics with simultaneous breakdown of the carrier into small molecules.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: November 24, 2020
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