Works Published in 2002
Displaying works 81 - 100 of 130 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2002 article
The hepatic endothelial carcinogen riddelliine induces endothelial apoptosis, mitosis, S phase, and p53 and hepatocytic vascular endothelial growth factor expression after short-term exposure
Nyska, A., Moomaw, C. R., Foley, J. F., Maronpot, R. R., Malarkey, D. E., Cummings, C. A., … Chan, P. C. (2002, November 1). TOXICOLOGY AND APPLIED PHARMACOLOGY, Vol. 184, pp. 153–164.
author keywords: pyrrolizidine alkaloid; endothelium; hemangiosarcoma; cytotoxicity; vascular endothelial growth factor; VEGFR2; BrdU; factor VIII-related antigen; von Willebrand factor; p53
MeSH headings : Administration, Oral; Animals; Apoptosis / drug effects; Bromodeoxyuridine / metabolism; Carcinogens / administration & dosage; Carcinogens / toxicity; Dose-Response Relationship, Drug; Endothelial Growth Factors / blood; Hepatocytes / drug effects; Hepatocytes / metabolism; Hepatocytes / pathology; Immunoenzyme Techniques; Intercellular Signaling Peptides and Proteins / blood; Kupffer Cells / drug effects; Kupffer Cells / metabolism; Kupffer Cells / pathology; Liver / drug effects; Liver / metabolism; Liver / pathology; Lymphokines / blood; Male; Mitosis; Pyrrolizidine Alkaloids / administration & dosage; Pyrrolizidine Alkaloids / toxicity; Rats; Rats, Inbred F344; S Phase / drug effects; Tumor Suppressor Protein p53 / metabolism; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 / metabolism; Vascular Endothelial Growth Factors; von Willebrand Factor / metabolism
TL;DR:
These changes may have promoted hemangiosarcoma development upon long-term exposure through endothelial adduct formation, apoptosis, proliferation of endothelial cells having undamaged and/or damaged DNA, and mutation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Single-tube nested PCR for detection of Tritrichomonas foetus in feline feces
JOURNAL OF CLINICAL MICROBIOLOGY, 40(11), 4126–4130.
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / parasitology; Cats; DNA Primers; DNA, Protozoan / analysis; DNA, Ribosomal / analysis; Feces / parasitology; Polymerase Chain Reaction / instrumentation; Polymerase Chain Reaction / methods; Protozoan Infections / diagnosis; Protozoan Infections / parasitology; Protozoan Infections, Animal; RNA, Ribosomal, 5.8S / genetics; Sensitivity and Specificity; Tritrichomonas foetus / genetics; Tritrichomonas foetus / isolation & purification
TL;DR:
The results demonstrate that the single-tube nested PCR is ideally suited for diagnostic testing of feline fecal samples that are found negative by direct microscopy and culturing and definitive identification of microscopically observable or cultivated organisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Pharmacokinetics and endometrial tissue concentrations of enrofloxacin and the metabolite ciprofloxacin after i.v. administration of enrofloxacin to mares
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 25(5), 343–350.
MeSH headings : Animals; Anti-Infective Agents / administration & dosage; Anti-Infective Agents / blood; Anti-Infective Agents / pharmacokinetics; Area Under Curve; Chromatography, High Pressure Liquid / veterinary; Ciprofloxacin / administration & dosage; Ciprofloxacin / blood; Ciprofloxacin / pharmacokinetics; Endometrium / metabolism; Enrofloxacin; Female; Fluoroquinolones; Horses / metabolism; Infusions, Intravenous / veterinary; Quinolones / administration & dosage; Quinolones / blood; Quinolones / pharmacokinetics
TL;DR:
Endometrial tissue concentrations taken from the mares after dosing showed that enrofloxacin and ciprofloxin both penetrate this tissue adequately after systemic administration and would attain concentrations high enough in the tissue fluids to treat infections of the endometrium caused by susceptible bacteria.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Nasal adenocarcinoma with diffuse metastases involving the orbit, cerebrum, and multiple cranial nerves in a horse
JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 221(10), 1460–1463.
MeSH headings : Adenocarcinoma / diagnosis; Adenocarcinoma / secondary; Adenocarcinoma / veterinary; Animals; Brain Neoplasms / diagnosis; Brain Neoplasms / secondary; Brain Neoplasms / veterinary; Cerebrospinal Fluid / chemistry; Cranial Nerve Neoplasms / diagnosis; Cranial Nerve Neoplasms / secondary; Cranial Nerve Neoplasms / veterinary; Diagnosis, Differential; Fatal Outcome; Horse Diseases / diagnosis; Horse Diseases / pathology; Horses; Male; Nose Neoplasms / diagnosis; Nose Neoplasms / pathology; Nose Neoplasms / veterinary; Orbital Neoplasms / diagnosis; Orbital Neoplasms / secondary; Orbital Neoplasms / veterinary; Prognosis; Tomography, X-Ray Computed / veterinary
TL;DR:
A 9-year-old Trakehner gelding examined because of right exophthalmus found a lack of menace response in the right eye, reduced direct and consensual right pupillary light reflexes, ventrolateral strabismus of the rightEye, mild right-sided facial asymmetry, a head tilt to the left, and increased extensor tone in theright limbs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 article
Heterobilharzia americana infection in a dog
Flowers, JR, Hammerberg, B., Wood, S. L., Malarkey, D. E., Dam, G. J., Levy, M. G., & McLawhorn, L. D. (2002, January 15). JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 220, pp. 193–196.
MeSH headings : Animals; Anthelmintics / therapeutic use; Antigens, Helminth / blood; Antigens, Helminth / immunology; Dog Diseases / diagnosis; Dog Diseases / drug therapy; Dog Diseases / parasitology; Dogs; Enzyme-Linked Immunosorbent Assay / veterinary; Feces / parasitology; Male; Parasite Egg Count / veterinary; Praziquantel / therapeutic use; Schistosomatidae / isolation & purification; Trematode Infections / diagnosis; Trematode Infections / drug therapy; Trematode Infections / parasitology; Trematode Infections / veterinary
TL;DR:
It is suggested that heterobilharziasis is underdiagnosed in dogs that have contact with water frequented by raccoons and inappropriate diagnostic procedures can foil accurate detection of this parasitic disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Effect of chemical interactions in pentachlorophenol mixtures on skin and membrane transport
TOXICOLOGICAL SCIENCES, 69(2), 295–305.
author keywords: pentachorophenol; mixtures; interactions; skin; absorption; surfactants; vehicle
MeSH headings : Animals; Chemical Phenomena; Chemistry, Physical; Diffusion; Ethanol / pharmacology; In Vitro Techniques; Insecticides / chemistry; Insecticides / pharmacokinetics; Insecticides / toxicity; Membranes / metabolism; Nicotinic Acids / pharmacology; Pentachlorophenol / chemistry; Pentachlorophenol / pharmacokinetics; Pentachlorophenol / toxicity; Permeability / drug effects; Pharmaceutical Vehicles; Skin Absorption / drug effects; Sodium Dodecyl Sulfate / pharmacology; Solvents / pharmacology; Viscosity
TL;DR:
It is demonstrated that modification in mixture composition with either a solvent and/or a surfactant can influence PCP diffusion in skin.
(via Semantic Scholar)
academic.oup.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
6. Clean Water and Sanitation
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 review
Applying the biopharmaceutics classification system to veterinary pharmaceutical products Part II. Physiological considerations
[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 54(6), 825–850.
author keywords: biopharmaceutics classification system; interspecies differences; veterinary oral drug absorption; animal models; food effects; lymphatic uptake
MeSH headings : Animal Feed; Animals; Biological Availability; Digestive System Physiological Phenomena; Food-Drug Interactions; Gastrointestinal Transit; Humans; Intestinal Absorption; Solubility; Species Specificity; Veterinary Drugs / administration & dosage; Veterinary Drugs / chemistry; Veterinary Drugs / pharmacokinetics
TL;DR:
This work considers the likely physiological causes for species-related differences in the absolute and relative bioavailability of orally administered pharmaceuticals, and examines the potential for these normal interspecies differences to reflect bioavailability changes that can occur with various human pathologies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Analysis of N,N-diethyl-m-toluamide in porcine skin perfusates using solid-phase extraction disks and reversed-phase high-performance liquid chromatography
Journal of Chromatography B, 780(1), 45–52.
author keywords: N,N-Diethyl-m-toluamide
MeSH headings : Animals; Chromatography, High Pressure Liquid / methods; DEET / analysis; Insect Repellents / analysis; Permeability; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Skin / chemistry; Swine
TL;DR:
An improved method was developed for determining transdermal diffusion of low levels of DEET following application to an in vitro porcine skin flow-through diffusion cell system and it was determined that DEET permeability in porcines skin was 2.55 x 10(-5)+/-0.54 x 10-5 cm/h.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2002 journal article
Thymocyte and peripheral blood T lymphocyte subpopulation changes in piglets following in utero infection with porcine reproductive and respiratory syndrome virus
VIROLOGY, 302(2), 363–372.
author keywords: PRRSV; thymus; thymocyte; T lymphocyte
MeSH headings : Animals; Animals, Newborn; Female; Infectious Disease Transmission, Vertical; Leukocytes, Mononuclear / immunology; Lymphocyte Count; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / immunology; Pregnancy; Pregnancy, Animal; Swine; Swine Diseases / immunology; Swine Diseases / virology; T-Lymphocyte Subsets / immunology; Thymus Gland / cytology; Thymus Gland / immunology; Uterus / virology
TL;DR:
It is shown that the number of thymocytes undergoing apoptosis was increased twofold in piglets infected with PRRSV and this results help explain the dramatic immunosuppression observed in neonatal animals infected in utero withPRRSV.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
The use of enzyme histochemistry in detecting cutaneous toxicity of three topically applied jet fuel mixtures
Toxicology Mechanisms and Methods, 12(1), 17–34.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Prostaglandin E-2 and reactive oxygen metabolite damage in the cecum in a pony model of acute colitis
Canadian Journal of Veterinary Research, 66(1), 50–54.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Pharmacokinetics of azithromycin in foals after i.v. and oral dose and disposition into phagocytes
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 25(2), 99–104.
MeSH headings : Actinomycetales Infections / drug therapy; Actinomycetales Infections / veterinary; Administration, Oral; Animals; Animals, Newborn; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Anti-Bacterial Agents / therapeutic use; Area Under Curve; Azithromycin / administration & dosage; Azithromycin / blood; Azithromycin / pharmacokinetics; Azithromycin / therapeutic use; Bronchoalveolar Lavage Fluid; Chromatography, High Pressure Liquid / veterinary; Female; Horse Diseases / drug therapy; Horses / metabolism; Infusions, Intravenous / veterinary; Macrophages, Alveolar / metabolism; Male; Phagocytes / metabolism; Rhodococcus equi
TL;DR:
The properties of azithromycin suggest that it may be an alternative to erythromycin for treatment of Rhodococcus equi pneumonia in foals and its disposition in plasma, polymorphonuclear leukocytes (PMN), and alveolar cells was examined to investigate this possibility.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Molecular characterization of multidrug-resistant Salmonella enterica subsp enterica serovar Typhimurium isolates from swine
JOURNAL OF CLINICAL MICROBIOLOGY, 40(8), 2813–2822.
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Conjugation, Genetic; DNA Fingerprinting; Drug Resistance, Multiple, Bacterial / genetics; Genetic Variation; Integrases / genetics; Microbial Sensitivity Tests; Phenotype; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Salmonella Infections, Animal / microbiology; Salmonella typhimurium / classification; Salmonella typhimurium / drug effects; Salmonella typhimurium / genetics; Swine; Swine Diseases / microbiology
TL;DR:
The findings show the widespread nature of the widespread diversity of multidrug-resistant Salmonella strains and the presence of conjugation-based resistance patterns and phage types, as well as the genetic basis for resistance among DT193 isolates.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Evaluation of a spontaneous canine model of immunoglobulin E- mediated food hypersensitivity: Dynamic changes in serum and fecal allergen-specific immunoglobulin E values relative to dietary change
Comparative Medicine, 52(4), 316–321.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Efficacy of monoclonal antibodies against defined antigens for passive immunotherapy of chronic gastrointestinal cryptosporidiosis
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 46(2), 275–282.
MeSH headings : Animals; Antibodies, Monoclonal / therapeutic use; Bioreactors; Body Weight / drug effects; Chronic Disease; Cryptosporidiosis / drug therapy; Cryptosporidiosis / parasitology; Cryptosporidium parvum / drug effects; Disease Models, Animal; Feces / parasitology; Female; Gastrointestinal Diseases / drug therapy; Gastrointestinal Diseases / parasitology; Immunization, Passive; Mice; Mice, SCID; Oocytes; Treatment Outcome
TL;DR:
The results indicate that anti-CSL MAb 3E2 has highly significant efficacy in reducing, but not eliminating, persistent C. parvum infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Dietary fibre level and enzyme inclusion affect nutrient digestibility and excreta characteristics in grower pigs
JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 82(14), 1606–1613.
author keywords: fibre; digestibility; feed enzymes; grower pigs
TL;DR:
Lowering the dietary NDF level or inclusion of fibre-degrading enzymes in high-fibre diets may offer relatively practical and easy methods for reducing waste production in pigs.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Development of skeletal muscle and expression of candidate genes in bovine fetuses from embryos produced in vivo or in vitro
BIOLOGY OF REPRODUCTION, 67(2), 401–408.
author keywords: conceptus; developmental biology; embryo; fetus; gene regulation; in vitro fertilization
MeSH headings : Animals; Blastocyst / physiology; Body Weight / physiology; Cattle; DNA Primers; Electrophoresis, Agar Gel; Embryo Transfer; Embryonic and Fetal Development / physiology; Female; Fertilization in Vitro; Fetus / metabolism; Gene Expression Regulation, Developmental / genetics; Glyceraldehyde-3-Phosphate Dehydrogenases / metabolism; In Vitro Techniques; Indicators and Reagents; Male; Muscle Fibers, Skeletal / physiology; Muscle Proteins / biosynthesis; Muscle Proteins / genetics; Muscle, Skeletal / anatomy & histology; Muscle, Skeletal / embryology; Pregnancy; RNA / biosynthesis; RNA / genetics; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
In vitro production of embryos resulted in fetuses with altered development of skeletal muscle fibers, and myostatin was identified as the candidate gene whose expression may contribute to the observed changes in muscle development of these fetuses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2002 journal article
Cranial coccygeal vertebral fractures in horses: 12 cases
Equine Veterinary Education, 14(4), 197–200.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
Cerebrospinal fluid centesis at the cerebellomedullary cistern of kittens
Contemporary Topics in Laboratory Animal Science, 41(5), 30–32.
Source: NC State University Libraries
Added: August 6, 2018
2002 journal article
C-terminal gp40 peptide analogs inhibit feline immunodeficiency virus: Cell fusion and virus spread
JOURNAL OF VIROLOGY, 76(18), 9079–9086.
MeSH headings : Amino Acid Sequence; Animals; Antiviral Agents / chemical synthesis; Antiviral Agents / chemistry; Antiviral Agents / pharmacology; Cats; Cell Fusion; Dose-Response Relationship, Drug; HIV Envelope Protein gp41 / chemistry; HIV-1 / drug effects; HIV-1 / physiology; HeLa Cells; Humans; Immunodeficiency Virus, Feline / drug effects; Immunodeficiency Virus, Feline / physiology; Membrane Fusion / drug effects; Microbial Sensitivity Tests; Molecular Sequence Data; Peptide Fragments / chemical synthesis; Peptide Fragments / chemistry; Peptide Fragments / pharmacology; Protein Structure, Tertiary; Viral Plaque Assay
TL;DR:
Synthetic peptides derived from the HR2 domain of the FIV gp41 protein are effective inhibitors of FIV infection, demonstrating the conservation of the gp41 ectodomain among lentiviruses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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