Works Published in 2016
Displaying works 121 - 140 of 221 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Specification grading in a distance-education nutrition course reduces students’ stress and improves grade distributions
Poultry Science, 95(Suppl. 1).
Source: NC State University Libraries
Added: June 20, 2019
2016 journal article
Germinal center dynamics during acute and chronic infection
Mathematical Biosciences and Engineering.
author keywords: B cells; Tfh cells; germinal centers; somatic hypermutations; mathematical models
MeSH headings : Acute Disease; Antigens / genetics; Antigens / immunology; B-Lymphocytes / immunology; B-Lymphocytes / physiology; Chronic Disease; Germinal Center / immunology; Humans; Infections / immunology; Infections / pathology; Models, Biological; Mutation; T-Lymphocytes, Helper-Inducer / immunology
TL;DR:
It is predicted that the T follicular helper cells are a limiting resource in driving large numbers of somatic hypermutations and possible mechanisms that can revert this limitation in the presence of non-mutating and mutating antigen are presented.
(via Semantic Scholar)
doi.org (publisher)
Source: ORCID
Added: June 19, 2019
2016 journal article
Cronobacter sakazakii - An unrecognised food borne pathogen, India
International Journal of Infectious Diseases, 45, 182.
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Sources: Crossref, ORCID
Added: February 18, 2019
2016 journal article
Fitness-valley crossing in subdivided asexual populations
BioRxiv.
TL;DR:
This work describes how subdivision alters the dynamics of adaptation from those in an equally sized unstructured population and gives a complete quantitative description of these dynamics for the island migration model, providing a general and intuitive framework for predicting the effects of spatial structure in other models and in natural populations.
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
2016 journal article
Rabbit hemorrhagic disease virus capsid, a versatile platform for foreign B-cell epitope display inducing protective humoral immune responses.
Scientific Reports, 6, 31844, http://europepmc.org/abstract/med/27549017
Source: ORCID
Added: February 11, 2019
2016 journal article
Complement Opsonization Promotes Herpes Simplex Virus 2 Infection of Human Dendritic Cells
Journal of Virology, 90(10), 4939–4950.
Ed(s): J. Jung
MeSH headings : Antibodies, Viral / immunology; Complement System Proteins / immunology; Complement System Proteins / metabolism; Cytokines / immunology; Dendritic Cells / immunology; Dendritic Cells / virology; Herpes Simplex / immunology; Herpesvirus 2, Human / immunology; Herpesvirus 2, Human / physiology; Humans; Opsonin Proteins / immunology; Virion / metabolism
TL;DR:
The results demonstrate that the presence of antibodies and complement in the genital environment can influence HSV-2 infection under in vitro conditions that reflect the in vivo situation.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: February 11, 2019
2016 journal article
Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs
PLOS ONE, 11(5), e0155676.
Contributors: A. Bähr *, T. Käser *, E. Kemter *, W. Gerner *, M. Kurome*, W. Baars*, N. Herbach*, K. Witter*
Ed(s): N. Câmara
MeSH headings : Abatacept / metabolism; Animals; Animals, Genetically Modified; Antigen-Presenting Cells / metabolism; Cloning, Organism; Conserved Sequence; Crosses, Genetic; Female; Fertilization in Vitro; Humans; Lymph Nodes / pathology; Lymphocyte Activation / immunology; Male; Promoter Regions, Genetic / genetics; Protein Binding; Reproduction / genetics; Sus scrofa / genetics; Sus scrofa / immunology; T-Lymphocytes / immunology
TL;DR:
The analysis of LEA29Y expression in serum and multiple organs of CAG-LEA transgenic pigs revealed that these animals produce a biologically active transgenic product at a considerable level and they present with an immune system affected by transgene expression, but can be maintained until sexual maturity and propagated by assisted reproduction techniques.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: February 11, 2019
2016 journal article
Flow cytometry as an improved method for the titration of Chlamydiaceae and other intracellular bacteria
Cytometry Part A, 89(5), 451–460.
Contributors: T. Käser *, J. Pasternak *, G. Hamonic*, M. Rieder*, K. Lai *, M. Delgado-Ortega*, V. Gerdts *, F. Meurens *
author keywords: Chlamydiaceae; Chlamydia suis; intracellular bacteria; titration; flow cytometry; FCM
MeSH headings : Cell Line; Chlamydiaceae / isolation & purification; Epithelial Cells / microbiology; Flow Cytometry / methods; Humans; Microscopy; Reproducibility of Results; Sensitivity and Specificity
TL;DR:
Flow cytometry offers a fast, cheap, precise, and reproducible alternative for the titration of intracellular bacteria like C. suis as a representative of other intrACEllular bacteria.
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
2016 journal article
Extended semen for artificial insemination in swine as a potential transmission mechanism for infectious Chlamydia suis
Theriogenology, 86(4), 949–956.
Contributors: G. Hamonic*, J. Pasternak *, T. Käser *, F. Meurens * & H. Wilson *
author keywords: Artificial insemination; Biosecurity; Chlamydia; Herd health; Semen; Semen extender
MeSH headings : Animals; Chlamydia / isolation & purification; Insemination, Artificial / veterinary; Semen / microbiology; Semen Analysis / veterinary; Semen Preservation; Staining and Labeling; Swine / physiology; Time Factors
TL;DR:
It is suggested that C suis remains viable and infectious during chilled storage and is globally unaffected by antibiotics in extender.
(via Semantic Scholar)
Sources: ORCID, Crossref
Added: February 11, 2019
2016 journal article
Expression of T-bet, Eomesodermin and GATA-3 in porcine αβ T cells
Developmental and Comparative Immunology, 60, 115–126.
Contributors: I. Rodríguez-Gómez *, S. Talker *, T. Käser *, M. Stadler*, S. Hammer *, A. Saalmüller *, W. Gerner *
author keywords: T-bet; GATA-3; Eomesodermin; Swine; alpha beta T cells
TL;DR:
The data so far support the hitherto reported roles for GATA-3 in T-cell development and T-bet for Th1 effector-differentiation, but question the role of Eomesodermin for memory formation of porcine T-cells.
(via Semantic Scholar)
Source: ORCID
Added: February 11, 2019
2016 journal article
NTPDase and 5′-nucleotidase as inflammatory markers in cattle naturally infected by Eurytrema coelomaticum
Comparative Immunology, Microbiology and Infectious Diseases, 48, 48–53.
Contributors: J. Fávero*, C. Schwertz *, P. Doleski *, D. Leal *, G. Machado* , A. Manzoni*, E. Silva*, M. Gabriel*
author keywords: Eurytrematosis; Cattle; NTPDase; 5 ' nucleotidase; Pathology
MeSH headings : 5'-Nucleotidase / blood; Abattoirs; Animals; Antigens, CD; Apyrase / blood; Biomarkers / blood; Brazil; Cattle; Cattle Diseases / enzymology; Cattle Diseases / parasitology; Cattle Diseases / pathology; Dicrocoeliidae; Inflammation / enzymology; Inflammation / pathology; Inflammation / veterinary; Lymphocytes; Pancreas / parasitology; Pancreas / pathology; Parasite Load; Trematode Infections / enzymology; Trematode Infections / parasitology; Trematode Infections / pathology; Trematode Infections / veterinary
TL;DR:
It is possible to suggest that NTPDase and 5'nucleotidase enzymes in cattle naturally infected by E. coleomanticum are involved in the modulation of inflammation, and they can act as markers of inflammatory response.
(via Semantic Scholar)
Source: ORCID
Added: January 4, 2019
2016 journal article
Metabolic Model-Based Integration of Microbiome Taxonomic and Metabolomic Profiles Elucidates Mechanistic Links between Ecological and Metabolic Variation
MSystems, 1(1).
Ed(s): L. Sanchez
author keywords: microbiome; multi-omic; metabolic modeling; community composition; metabolomics
TL;DR:
A surprisingly large proportion of metabolite variation in the vaginal microbiome can be predicted based on species composition (including dramatic shifts associated with disease), identify putative mechanisms underlying these predictions, and evaluate the roles of individual bacterial species and genes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, (118).
author keywords: Infection; Issue 118; Clostridium difficile; mouse model; antibiotic; colonization; cytotoxicity; histology; inflammation; Vero cells
MeSH headings : Animals; Anti-Bacterial Agents; Cefoperazone / pharmacology; Clostridioides difficile / drug effects; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL
TL;DR:
This cefoperazone mouse model of CDI proves a valuable experimental platform to assess the effects of novel therapeutics on the amelioration of clinical disease and on the restoration of colonization resistance against C. difficile.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 article
The Strange, Expanding World of Animal Hepaciviruses
ANNUAL REVIEW OF VIROLOGY, VOL 3, Vol. 3, pp. 53–75.
author keywords: hepatitis C virus; pegivirus; hepegivirus; virome; virus evolution; animal models
MeSH headings : Animals; Cattle / virology; Chiroptera / virology; Colobus / virology; Flavivirus / classification; Flavivirus / genetics; GB virus A / classification; GB virus A / genetics; GB virus C / classification; GB virus C / genetics; Genetic Variation / genetics; Genome, Viral / genetics; Hepacivirus / classification; Hepacivirus / genetics; Hepatitis C / veterinary; Hepatitis C / virology; Horses / virology; Host Specificity; Humans; Pestivirus / classification; Pestivirus / genetics; Sharks / virology
TL;DR:
This review summarizes the significance of these studies and discusses current thinking about the origin and evolution of the animal hepaciviruses as well as their potential usage as surrogate models for the study of hepatitis C virus.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Patient characteristics, histopathological findings and outcome in 97 cats with extranodal subcutaneous lymphoma (2007-2011)
Veterinary and Comparative Oncology, 14, 8–20.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Pathogeny of Fatigued Walking Condition in Pekin Ducks
AVIAN DISEASES, 60(4), 731–738.
author keywords: ducks; fatigue syndrome; incubation; eggshell conductance
MeSH headings : Animals; Bone and Bones / embryology; Bone and Bones / pathology; Ducks / embryology; Egg Shell / chemistry; Egg Shell / embryology; Egg Shell / pathology; Female; Heart / embryology; Male; Poultry Diseases / embryology; Poultry Diseases / pathology; Temperature
TL;DR:
The changes in bone development during incubation and posthatch life were related to duck FWC presence during transportation to the processing plant.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Markov Networks of Collateral Resistance: National Antimicrobial Resistance Monitoring System Surveillance Results from Escherichia coli Isolates, 2004-2012
PLOS COMPUTATIONAL BIOLOGY, 12(11).
Ed(s): M. Tanaka
MeSH headings : Anti-Bacterial Agents / therapeutic use; Bacterial Infections / epidemiology; Bacterial Infections / microbiology; Computer Simulation; Drug Resistance, Bacterial; Escherichia coli / drug effects; Escherichia coli / isolation & purification; Humans; Markov Chains; Models, Statistical; Population Surveillance / methods; Prevalence; Reproducibility of Results; Risk Assessment / methods; Sensitivity and Specificity; Treatment Outcome
TL;DR:
The current method provides a novel method to study the joint resistance distribution, but additional work is required to unite the underlying biological and genetic characteristics of the isolates with the current results derived from phenotypic data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Helminth Parasites of Pit Vipers from North Carolina
SOUTHEASTERN NATURALIST, 15(4), 729–741.
TL;DR:
7 new host records and 7 new geographic-distribution records with notes on host—parasite biology are reported.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Antibiotic-Induced Alterations of the Gut Microbiota Alter Secondary Bile Acid Production and Allow for Clostridium difficile Spore Germination and Outgrowth in the Large Intestine
MSphere, 1(1).
Ed(s): C. Ellermeier
author keywords: Clostridium difficile; bile acids; antibiotics; microbiota; colonization resistance
TL;DR:
It is hypothesized that the depletion of microbial members responsible for converting primary bile acids into secondary bile acid reduces resistance to Clostridium difficile colonization, suggesting that targeting growth of C.difficile will prove most important for future therapeutics and that antibiotic-related changes are organ specific.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
An Evaluation of Food as a Potential Source for Clostridium difficile Acquisition in Hospitalized Patients
INFECTION CONTROL AND HOSPITAL EPIDEMIOLOGY, 37(12), 1401–1407.
MeSH headings : Academic Medical Centers; Adult; Aged; Aged, 80 and over; Clostridioides difficile / isolation & purification; Cross Infection / microbiology; Enterocolitis, Pseudomembranous; Feces / microbiology; Female; Food Microbiology; Hospitalization; Humans; Inpatients; Male; Middle Aged; Missouri; Prospective Studies; Young Adult
TL;DR:
Stochastic modeling indicated contaminated hospital food would be responsible for less than 1 newly colonized patient per 1,000 hospital admissions, and modeling suggests hospital food is unlikely to be a source of C. difficile acquisition.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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