Works Published in 2016
Displaying works 161 - 180 of 221 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 article
Pathology in Practice
Meichner, K., Montgomery, S. A., Borst, L. B., Murphy, K. M., & Grindem, C. B. (2016, November 1). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 249, pp. 1023–1026.
MeSH headings : Animals; Biopsy; Dog Diseases / pathology; Dog Diseases / therapy; Dogs; Male; Sertoli Cell Tumor / diagnosis; Sertoli Cell Tumor / pathology; Sertoli Cell Tumor / veterinary; Skin Neoplasms / pathology; Skin Neoplasms / veterinary; Testicular Neoplasms / diagnosis; Testicular Neoplasms / pathology; Testicular Neoplasms / veterinary
TL;DR:
In collaboration with the American College of Veterinary Pathologists, this work presents a probabilistic procedure to identify the immune checkpoints in the connective tissue of the immune system and results indicate which immune checkpoints are responsible for disease progression.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Mathematical modeling tools to study preharvest food safety
Microbiology Spectrum, 4(4).
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Listeria monocytogenes wall teichoic acid decoration in virulence and cell-to-cell spread
MOLECULAR MICROBIOLOGY, 101(5), 714–730.
MeSH headings : Animals; Bacteriophages / metabolism; Cell Membrane / metabolism; Cell Wall / metabolism; Female; Listeria monocytogenes / metabolism; Listeria monocytogenes / pathogenicity; Listeriosis / microbiology; Liver / microbiology; Mice; Mutation; Peptidoglycan / metabolism; Spleen / microbiology; Teichoic Acids / metabolism; Virulence
TL;DR:
Identification and interruption of WTA decoration pathways may provide a general strategy to discover non‐antibiotic therapeutics for gram positive infections.
(via Semantic Scholar)
onlinelibrary.wiley.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Isolation and characterization of atypical Listeria monocytogenes associated with a canine urinary tract infection
Journal of Veterinary Diagnostic Investigation, 28(5), 604–607.
author keywords: Canine listeriosis; canine urinary tract infection; Listeria monocytogenes
MeSH headings : Animals; Diabetes Mellitus, Type 2 / complications; Diabetes Mellitus, Type 2 / veterinary; Diagnosis, Differential; Dog Diseases / diagnosis; Dog Diseases / microbiology; Dogs; Listeria monocytogenes / isolation & purification; Listeriosis / complications; Listeriosis / microbiology; Listeriosis / veterinary; Male; Urinary Tract Infections / complications; Urinary Tract Infections / microbiology; Urinary Tract Infections / veterinary
TL;DR:
The serotype of the L. monocytogenes isolate was determined to be 1/2a (3a), and a nucleotide substitution was detected at residue 145 in the promoter prfA region, within the critical helix-turn-helix motif of PrfA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2016 journal article
Impact of microbial derived secondary bile acids on colonization resistance against Clostridium difficile in the gastrointestinal tract
ANAEROBE, 41, 44–50.
author keywords: Clostridium difficile; Secondary bile acids; Colonization resistance; Gut microbiota; Antibiotics
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Anti-Bacterial Agents / therapeutic use; Bile Acids and Salts / pharmacology; Bile Acids and Salts / physiology; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Disease Susceptibility; Drug Resistance, Neoplasm; Enterocolitis, Pseudomembranous / drug therapy; Enterocolitis, Pseudomembranous / microbiology; Gastrointestinal Microbiome; Gastrointestinal Tract / microbiology; Humans
TL;DR:
Rational manipulation of secondary bile acids may prove beneficial as a treatment for patients with CDI and shed light on how bile acid play a role in colonization resistance against C. difficile.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Efficacy of Various HVT Vaccines (Conventional and Recombinant) Against Marek's Disease in Broiler Chickens: Effect of Dose and Age of Vaccination
AVIAN DISEASES, 60(3), 662–668.
author keywords: HVT; recombinant; vaccination; in ovo; MDV; control
MeSH headings : Age Factors; Animals; Chickens; Dose-Response Relationship, Immunologic; Female; Herpesvirus 1, Meleagrid / immunology; Marek Disease / prevention & control; Marek Disease / virology; Marek Disease Vaccines / administration & dosage; Marek Disease Vaccines / pharmacology; Poultry Diseases / prevention & control; Poultry Diseases / virology; Vaccination / veterinary; Vaccines, Synthetic / administration & dosage; Vaccines, Synthetic / pharmacology
TL;DR:
The results show that each HVT product is unique, regardless of being conventional or recombinant, in their ability to protect against MD and might require different PFUs to achieve its maximum efficacy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Early Activation of Th2/Th22 Inflammatory and Pruritogenic Pathways in Acute Canine Atopic Dermatitis Skin Lesions
JOURNAL OF INVESTIGATIVE DERMATOLOGY, 136(10), 1961–1969.
MeSH headings : Adaptive Immunity / immunology; Animals; Cytokines / genetics; Cytokines / immunology; Dermatitis, Atopic / immunology; Dermatophagoides farinae / immunology; Disease Models, Animal; Dogs; Female; Immunity, Innate / immunology; Inflammation / immunology; Interleukin-9 / genetics; Interleukin-9 / immunology; Interleukins / genetics; Interleukins / immunology; Male; Pruritus / immunology; Skin / immunology; Skin / pathology; Species Specificity; Th2 Cells / immunology; Time Factors; Up-Regulation / genetics
TL;DR:
Experimental acute canine house dust mite-induced AD lesions exhibit an activation of innate and adaptive immune responses and pruritogenic pathways similar to those seen in humans with acute AD, thereby validating this model to test innovative therapeutics modalities for this disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Dietary Iron Deficiency and Oversupplementation Increase Intestinal Permeability, Ion Transport, and Inflammation in Pigs
JOURNAL OF NUTRITION, 146(8), 1499–1505.
author keywords: intestinal physiology; iron; intestinal barrier function; porcine; inflammation
MeSH headings : Animals; Biological Transport; Diet; Dietary Supplements; Duodenum; Inflammation / etiology; Inflammation / metabolism; Interleukin-1beta / metabolism; Interleukin-5 / metabolism; Intestinal Mucosa / physiopathology; Ions / metabolism; Iron / administration & dosage; Iron / metabolism; Iron Deficiencies; Iron, Dietary / administration & dosage; Iron, Dietary / metabolism; Liver; Male; Malondialdehyde / metabolism; Neutrophils / metabolism; Nutritional Status; Overnutrition; Permeability; Swine; Tumor Necrosis Factor-alpha / metabolism
TL;DR:
It is suggested that adequate but not oversupplementation of dietary iron in pigs is required to maintain intestinal barrier health and function.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2016 journal article
Development of a HS-SPME-GC-MS/MS Method for the Quantitation of Thymol and Carvacrol in Bovine Matrices and To Determine Residue Depletion in Milk and. Tissues
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 64(41), 7856–7865.
author keywords: organic; thymol; carvacrol; milk; bovine tissues; residues
TL;DR:
A rapid and sensitive HS-SPME-GC-MS/MS method was developed for the detection of thymol and carvacrol in bovine milk, plasma, liver, kidney, and fat and stability studies showed that both compounds are stable over a 2 month period.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Assessment of penetrant and vehicle mixture properties on transdermal permeability using a mixed effect pharmacokinetic model of ex vivo porcine skin
Biopharmaceutics & Drug Disposition, 37(7), 387–396.
author keywords: quantitative structure property relationship; transdermal permeability; vehicle mixture; ex vivo; mixed-effect model
MeSH headings : Administration, Cutaneous; Animals; Models, Biological; Permeability; Pharmaceutical Preparations / metabolism; Quantitative Structure-Activity Relationship; Skin / metabolism; Skin Absorption; Swine
TL;DR:
A mixed effect, pharmacokinetic tissue model was used to model finite dose, transdermal, absorption data from IPPSF experiments for 12 penetrants dosed in up to 10 different vehicles and was able to identify permeability constant, while accounting for between and within unit variability, across the entire data set.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2016 journal article
Transient activation of mucosal effector immune responses by resident intestinal bacteria in normal hosts is regulated by interleukin-10 signalling
IMMUNOLOGY, 148(3), 304–314.
author keywords: germ-free mice; interleukin-10; resident bacteria
MeSH headings : Animals; Antigens, Bacterial / immunology; B-Lymphocytes / immunology; Cells, Cultured; Colitis / etiology; Colitis / immunology; Disease Models, Animal; Escherichia coli / immunology; Escherichia coli Infections / complications; Escherichia coli Infections / immunology; Immunity, Mucosal; Interferon-gamma / metabolism; Interleukin-10 / genetics; Interleukin-10 / metabolism; Intestines / immunology; Intestines / microbiology; Lymphocyte Activation; Mice; Mice, 129 Strain; Mice, Knockout; Signal Transduction; Th1 Cells / immunology
TL;DR:
Findings show that a resident E. coli that induces chronic colitis in monoassociated IL‐10‐deficient mice rapidly but transiently activates the effector immune system in normal hosts, in parallel with induction of protective IL-10 produced by B cells and CD4+ cells that subsequently suppresses this response to mediate mucosal homeostasis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Mitochondrial Genome Sequences and Structures Aid in the Resolution of Piroplasmida phylogeny
PLOS ONE, 11(11).
MeSH headings : DNA, Protozoan / genetics; Genome, Mitochondrial; Humans; Phylogeny; Piroplasmida / classification; Piroplasmida / genetics; Protozoan Infections / parasitology
TL;DR:
Phylogenetic analysis of concatenated mitochondrial and 18S sequences as well as cox1 amino acid sequence identified five distinct Piroplasmida groups, each of which possesses a unique mitochondrial genome structure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
MAVS-dependent host species range and pathogenicity of human hepatitis A virus
SCIENCE, 353(6307), 1541–1545.
MeSH headings : Adaptor Proteins, Signal Transducing / genetics; Adaptor Proteins, Signal Transducing / immunology; Animals; Apoptosis; Disease Models, Animal; Hepatitis A / immunology; Hepatitis A / pathology; Hepatitis A / virology; Hepatitis A virus / immunology; Hepatocytes / immunology; Hepatocytes / pathology; Hepatocytes / virology; Host-Pathogen Interactions / immunology; Humans; Interferon Regulatory Factor-3 / genetics; Interferon Regulatory Factor-3 / immunology; Interferon Regulatory Factor-7 / genetics; Interferon Regulatory Factor-7 / immunology; Interferon Type I / immunology; Liver / immunology; Liver / pathology; Liver / virology; Mice; Mice, Knockout; Receptor, Interferon alpha-beta / genetics; Receptor, Interferon alpha-beta / immunology; Receptors, Interferon / genetics; Receptors, Interferon / immunology; Signal Transduction / immunology; Species Specificity
TL;DR:
A murine model of hepatitis A virus (HAV) infection that recapitulates critical features of type A hepatitis in humans is described and it is demonstrated that the capacity of HAV to evade MAVS-mediated type I interferon responses defines its host species range.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Infective endocarditis in 13 cats
JOURNAL OF VETERINARY CARDIOLOGY, 18(3), 213–225.
author keywords: BAPGM; Bartonella; Duke criteria; Vegetative lesion
MeSH headings : Animals; Anti-Bacterial Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / physiopathology; Cats; Endocarditis, Bacterial / diagnosis; Endocarditis, Bacterial / drug therapy; Endocarditis, Bacterial / physiopathology; Endocarditis, Bacterial / veterinary; Female; Male; Prognosis; Retrospective Studies; Treatment Outcome
TL;DR:
In contrast to dogs, cats with IE typically present with clinical signs consistent with cardiac decompensation and locomotor abnormalities suggestive of either thromboembolic disease or inflammatory arthritis, and prognosis is grave.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
House Finch (Haemorhous mexicanus) Conjunctivitis, and Mycoplasma spp. Isolated from North American Wild Birds, 1994-2015
JOURNAL OF WILDLIFE DISEASES, 52(3), 669–673.
author keywords: Conjunctivitis; Haemorhous mexicanus; House Finch; Mycoplasma gallisepticum; Mycoplasma gypis; Mycoplasma sturni; mycoplasmosis; wild birds
MeSH headings : Animals; Animals, Wild; Bird Diseases / microbiology; Conjunctivitis, Bacterial / epidemiology; Conjunctivitis, Bacterial / microbiology; Conjunctivitis, Bacterial / veterinary; Finches; Mycoplasma / classification; Mycoplasma / isolation & purification; Mycoplasma Infections / epidemiology; Mycoplasma Infections / microbiology; Mycoplasma Infections / veterinary; North America / epidemiology; Retrospective Studies
TL;DR:
Accumulating evidence shows that a diverse range of wild bird species may carry or have been exposed to M. gallisepticum in the US, as in Europe and Asia, and may actually be the exception that has allowed us to identify the broader epidemiologic picture.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
External beam radiation therapy of squamous cell carcinoma in the beak of an African grey parrot (Psittacus timneh)
Journal of Avian Medicine and Surgery, 30(3), 250–256.
MeSH headings : Animals; Beak / pathology; Bird Diseases / radiotherapy; Carcinoma, Squamous Cell / radiotherapy; Carcinoma, Squamous Cell / veterinary; Male; Parrots
TL;DR:
Squamous cell carcinoma of the rhinotheca was diagnosed in a 34-year-old timneh African grey parrot with a 2-year history of beak abnormalities and died approximately 7 months after diagnosis and 4 months after cessation of radiation treatment.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Effect of high-pressure processing of bovine colostrum on immunoglobulin G concentration, pathogens, viscosity, and transfer of passive immunity to calves
JOURNAL OF DAIRY SCIENCE, 99(11), 8575–8588.
author keywords: high-pressure processing; bovine colostrum; pasteurization; Mycobacterium avium ssp paratuberculosis
MeSH headings : Animals; Animals, Newborn; Cattle; Colostrum / immunology; Escherichia coli / immunology; Female; Immunoglobulin G / blood; Pilot Projects; Staphylococcus aureus / immunology; Viscosity
TL;DR:
High-pressure processing of bovine colostrum maintains an acceptable IgG level while decreasing bacterial and viral counts, and is suggested to be appropriate for on-farm use.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Distinction and connection between contact network, social network, and disease transmission network
PREVENTIVE VETERINARY MEDICINE, 131, 8–11.
author keywords: Animal contact network; Social network; Disease transmission network; Distinction; Connection
MeSH headings : Animal Husbandry; Animals; Cattle; Cattle Diseases / transmission
TL;DR:
A modeling framework is established to track potential disease transmission dynamics and construct transmission network based on the observed animal contact network and demonstrate that social and disease transmission networks can be derived as spanning subgraphs of contact network.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Clinical and microscopic features of generalized discoid lupus erythematosus in dogs (10 cases)
VETERINARY DERMATOLOGY, 27(6), 488-+.
MeSH headings : Animals; Dog Diseases / pathology; Dogs; Female; Lupus Erythematosus, Discoid / pathology; Lupus Erythematosus, Discoid / veterinary; Male; Skin / pathology
TL;DR:
Observations support the existence of a canine homologue of human GDLE, a newly recognized canine variant of chronic cutaneous lupus erythematosus that is not well characterized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Basic Reproduction Number and Transmission Dynamics of Common Serogroups of Enterohemorrhagic Escherichia coli
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 82(18), 5612–5620.
MeSH headings : Adhesins, Bacterial / genetics; Animals; Basic Reproduction Number; Cattle; Cross-Sectional Studies; Disease Transmission, Infectious; Enterohemorrhagic Escherichia coli / classification; Enterohemorrhagic Escherichia coli / isolation & purification; Environmental Exposure; Escherichia coli Infections / epidemiology; Escherichia coli Infections / microbiology; Escherichia coli Infections / transmission; Escherichia coli Infections / veterinary; Escherichia coli Proteins / genetics; O Antigens / analysis; Prevalence; Serogroup; Shiga Toxins / genetics; United States / epidemiology
TL;DR:
A Bayesian modeling framework is described to estimate basic reproduction numbers of multiple serotypes of Shiga toxin-producing Escherichia coli according to a cross-sectional study and can be readily expanded to other pathogen systems in order to estimate the pathogen and external factors that influence spread of infectious agents.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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