Works Published in 2018
Displaying works 161 - 180 of 238 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2018 journal article
Porcine Reproductive and Respiratory Syndrome Virus Type 1.3 Lena Triggers Conventional Dendritic Cells 1 Activation and T Helper 1 Immune Response Without Infecting Dendritic Cells
Frontiers in Immunology, 9.
author keywords: PRRSV; Lena; lung; dendritic cells; cDc1; Th1 response; cellular response
MeSH headings : Animals; Biomarkers; Cytokines / metabolism; Dendritic Cells / immunology; Dendritic Cells / metabolism; Lymphocyte Activation / immunology; Lymphocyte Culture Test, Mixed; Porcine Reproductive and Respiratory Syndrome / immunology; Porcine Reproductive and Respiratory Syndrome / metabolism; Porcine Reproductive and Respiratory Syndrome / virology; Porcine respiratory and reproductive syndrome virus / immunology; Swine; T-Lymphocyte Subsets / immunology; T-Lymphocyte Subsets / metabolism; T-Lymphocytes, Helper-Inducer / immunology; T-Lymphocytes, Helper-Inducer / metabolism
TL;DR:
In vitro investigation of T helper polarization and cytokines production demonstrate that Lena induces a higher Th1 polarization and IFNγ secretion than FL13 and LV, which suggests an activation of cDC1 by Lena associated with a Th1 immune response polarization.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, Crossref
Added: October 16, 2018
2018 article
Extralabel drug use in small ruminants
Martin, K. L., Clapham, M. O., Davis, J. L., Baynes, R. E., Lin, Z., Vickroy, T. W., … Tell, L. A. (2018, October 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 253, pp. 1001–1009.
MeSH headings : Animals; Drug Residues; Goat Diseases / drug therapy; Goats; Legislation, Drug; Off-Label Use; Sheep; Sheep Diseases / drug therapy; United States; United States Food and Drug Administration; Veterinary Drugs / administration & dosage; Veterinary Drugs / pharmacokinetics
TL;DR:
The purpose of this digest is to update a previous FARAD Digest2 concerning small ruminants and provide veterinarians with summary information regarding ELDU in smallRuminants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 16, 2018
2018 journal article
Multiloculated solitary (unicameral) bone cyst in a young dog
Veterinary Clinical Pathology, 47(3), 484–488.
author keywords: Canine; cytology; lytic; osseous; osteoclast; skeletal
MeSH headings : Animals; Bone Cysts / complications; Bone Cysts / diagnostic imaging; Bone Cysts / pathology; Bone Cysts / veterinary; Dog Diseases / diagnostic imaging; Dog Diseases / pathology; Dogs; Female; Femur / diagnostic imaging; Femur / pathology; Lameness, Animal / etiology; Lameness, Animal / pathology; Radiography / veterinary
TL;DR:
A 20-month-old female spayed Staffordshire Terrier presented to the Orthopedic Surgery Service at North Carolina State University Veterinary Teaching Hospital for evaluation of a 6-week history of toe-touching to nonweight-bearing lameness, and amputation of the right hind limb was performed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, Crossref, NC State University Libraries
Added: October 16, 2018
2018 journal article
Relation of contaminants to fish intersex in riverine sport fishes
Science of The Total Environment, 643, 73–89.
author keywords: Endocrine active compounds; Endocrine disruption; Bass; Polycyclic aromatic hydrocarbons; Ethinylestradiol; Mercury
MeSH headings : Animals; Disorders of Sex Development / epidemiology; Disorders of Sex Development / veterinary; Environmental Monitoring; Female; Fish Diseases / epidemiology; Fishes / physiology; Male; North Carolina; Rivers / chemistry; South Carolina; Sports; Water Pollutants, Chemical / analysis; Water Pollution, Chemical / statistics & numerical data
TL;DR:
Polycyclic aromatic hydrocarbons, ethinylestradiol, and heavy metals were the most prevalent contaminants that exceeded effect levels for the protection of aquatic organisms and principal component analysis identified waterborne PAHs as the most correlated environmental contaminant with intersex occurrence and severity in black bass and sunfish.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, Crossref
Added: October 16, 2018
2018 journal article
Enrichment Preferences of FIV-Infected and Uninfected Laboratory-Housed Cats
VIRUSES-BASEL, 10(7).
author keywords: FIV; enrichment; welfare; feline; laboratory animal
MeSH headings : Animals; Animals, Laboratory; Cats; Feline Acquired Immunodeficiency Syndrome / virology; Immunodeficiency Virus, Feline / physiology
TL;DR:
Cats used in a longitudinal study of the effects of chronic feline immunodeficiency virus (FIV) infection were used and it was found that cats elected to be brushed, preferred social interaction and play with the laser to the ball, and preferred to scratch on an inclined-box toenail conditioning object compared to a horizontal, circular toenails conditioning object.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 16, 2018
2018 journal article
Comparison of the pharmacokinetics of plant-based treatments in milk and plasma of USDA organic dairy cattle with and without mastitis
FOOD ADDITIVES AND CONTAMINANTS PART A-CHEMISTRY ANALYSIS CONTROL EXPOSURE & RISK ASSESSMENT, 35(9), 1716–1727.
author keywords: Pharmacology; milk; organic; thymol; carvacrol; bovine; cattle
MeSH headings : Animals; Cattle; Cymenes; Dairying; Female; Food, Organic / analysis; Garlic / chemistry; Milk / chemistry; Monoterpenes / blood; Thymol / blood; United States; United States Department of Agriculture
TL;DR:
Study of the pharmacokinetics of 3 compounds used on organic both healthy and mastitic organic dairy cattle found levels remained below the limit of detection in milk and plasma and thus no withdrawal time appears to be needed for milk.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: October 16, 2018
2018 journal article
Dosing Regimen of Enrofloxacin Impacts Intestinal Pharmacokinetics and the Fecal Microbiota in Steers
FRONTIERS IN MICROBIOLOGY, 9.
author keywords: antimicrobial resistance; fluoroquinolone; cattle; microbiome; pharmacokinetics
TL;DR:
Both dosing regimens of enrofloxacin achieve high concentrations in the intestinal lumen, and the rapid elimination mitigates long-term impacts on fecal E. coli resistance and the microbiota.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018
2018 journal article
Factors associated with strongyle infection in goats at the individual and farm level
JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 253(7), 907–917.
MeSH headings : Animals; Cross-Sectional Studies; Female; Goat Diseases / epidemiology; Goat Diseases / parasitology; Goats; Male; North Carolina / epidemiology; Parasite Egg Count / veterinary; Prevalence; Strongylida Infections / epidemiology; Strongylida Infections / veterinary; Strongyloides / isolation & purification
TL;DR:
The finding that farms with no history of anthelmintic use had the lowest mean FECs suggested that a focus on preventative measures could reduce the need for anthel mintic drugs and, by extension, lessen the opportunity for the development of anesthetic resistance.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 16, 2018
2018 journal article
Editorial
Journal of Veterinary Pharmacology and Therapeutics, 41(3), 355–355.
MeSH headings : Editorial Policies; Periodicals as Topic; Veterinary Medicine
Sources: Web Of Science, Crossref
Added: August 6, 2018
2018 journal article
Use of real-time PCR to rule out Marek's disease in the diagnosis of peripheral neuropathy
AVIAN PATHOLOGY, 47(4), 427–433.
author keywords: Peripheral neuropathy; Marek's disease; diagnosis; real-time PCR; nerve enlargement
MeSH headings : Animals; Chickens / virology; DNA, Viral / analysis; DNA, Viral / genetics; Diagnosis, Differential; Mardivirus / genetics; Mardivirus / isolation & purification; Marek Disease / diagnosis; Marek Disease / pathology; Marek Disease / virology; Peripheral Nervous System Diseases / diagnosis; Peripheral Nervous System Diseases / pathology; Peripheral Nervous System Diseases / veterinary; Poultry Diseases / diagnosis; Poultry Diseases / pathology; Real-Time Polymerase Chain Reaction / veterinary
TL;DR:
A case report shows for the first time how real-time PCR to detect oncogenic MDV is a very valuable tool in the differential diagnosis of PN and MD.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2018 journal article
Treatment of carprofen overdose with therapeutic plasma exchange in a dog
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 28(4), 356–360.
author keywords: canine; kidney injury; NSAID toxicity; plasmapheresis
MeSH headings : Animals; Anti-Inflammatory Agents, Non-Steroidal / poisoning; Carbazoles / poisoning; Diagnosis, Differential; Dog Diseases / blood; Dog Diseases / diagnosis; Dog Diseases / therapy; Dogs; Drug Overdose / diagnosis; Drug Overdose / therapy; Drug Overdose / veterinary; Female; Plasma Exchange / veterinary
TL;DR:
Although recent studies suggest that this particular dog may not have received a toxic dose, a 51% reduction of plasma carprofen concentration was achieved over 180 minutes, and TPE may be beneficial for treatment of dogs that have ingested higher doses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Shifts in the Gut Metabolome and Clostridium difficile Transcriptome throughout Colonization and Infection in a Mouse Model
MSPHERE, 3(2).
Contributors: J. Fletcher n, S. Erwin n , C. Lanzas n & C. Theriot n
author keywords: Clostridium difficile; amino acids; intestinal colonization; metabolomics; peptides; transcriptomics
MeSH headings : Amino Acids, Branched-Chain / metabolism; Animals; Anti-Bacterial Agents / administration & dosage; Carbohydrate Metabolism; Cecum / microbiology; Clostridioides difficile / metabolism; Clostridium Infections / metabolism; Clostridium Infections / microbiology; Female; Gastrointestinal Microbiome; Gene Expression Profiling; Male; Mass Spectrometry; Metabolome; Metabolomics; Mice; Mice, Inbred C57BL; Peptide Hydrolases / genetics; Proline / metabolism; Sequence Analysis, RNA; Transcriptome
TL;DR:
The gut environment after antibiotics and during the initial stages of C. difficile colonization and infection is defined and amino acids, in particular, proline and branched-chain amino acids and carbohydrates decrease in abundance over time and that C.difficile gene expression is consistent with their utilization in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018
2018 journal article
Range Expansion of Fascioloides magna in North Carolina
SOUTHEASTERN NATURALIST, 17(2), 365–370.
TL;DR:
An increased impact on North Carolina livestock is likely with the possible range expansion of Giant Liver Fluke, which may be related to the increase in populations of White-tailed Deer.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Pharmacokinetics of orbifloxacin in crucian carp (Carassius auratus) after intravenous and intramuscular administration
JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 41(4), 599–604.
author keywords: bioavailability; crucian carp; intramuscular injection; orbifloxacin; pharmacokinetics
MeSH headings : Animals; Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / blood; Anti-Bacterial Agents / pharmacokinetics; Chromatography, High Pressure Liquid / veterinary; Ciprofloxacin / administration & dosage; Ciprofloxacin / analogs & derivatives; Ciprofloxacin / blood; Ciprofloxacin / pharmacokinetics; Goldfish / blood; Goldfish / metabolism; Half-Life; Injections, Intramuscular / veterinary; Injections, Intravenous / veterinary
TL;DR:
It was shown that orbifloxacin was completely but relatively slowly absorbed, extensively distributed, and slowly eliminated in crucian carp, and an orbif loxacins dosage of 10 mg/kg administered intravenously or intramuscularly would be expected to successfully treat crucian fish infected by strains with MIC values ≤0.5 μg/ml.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Microbial integrity of preservative-free alfaxalone in a multiple-use system for two storage conditions and three handling techniques
AMERICAN JOURNAL OF VETERINARY RESEARCH, 79(7), 704–710.
MeSH headings : Anesthetics / administration & dosage; Animals; Colony Count, Microbial; Drug Contamination; Drug Packaging; Drug Storage; North Carolina; Pregnanediones / administration & dosage; Quality Control; Refrigeration; Sterilization; Temperature; Time Factors; United States; United States Food and Drug Administration; Universities
TL;DR:
Alfaxalone is supported for 7 days when refrigerated and handled with a single puncture of the stopper by use of a protected port (closed system transfer device or nonclosed dispensing pin) and would appear to be a practical alternative for an injectable anesthetic.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
MICROBIOME Gut microbiome-mediated bile acid metabolism regulates liver cancer via NKT cells
Science, 360(6391), 876-.
Source: NC State University Libraries
Added: August 6, 2018
2018 book
Gross pathology of avian diseases: Text and atlas
Jacksonville, Fla.: American Association of Avian Pathologists.
Source: NC State University Libraries
Added: August 6, 2018
2018 journal article
Evaluation of potential serum biomarkers of hepatic fibrosis and necroinflammatory activity in dogs with liver disease
JOURNAL OF VETERINARY INTERNAL MEDICINE, 32(3), 1009–1018.
author keywords: AST; CCL2; CRP; hepatitis; IL-6; MCP-1
MeSH headings : Alanine Transaminase / blood; Animals; Aspartate Aminotransferases / blood; Biomarkers / blood; Biopsy / veterinary; Chemokine CCL2 / blood; Cross-Sectional Studies; Dog Diseases / blood; Dog Diseases / diagnosis; Dogs; Female; Interleukin-6 / blood; Liver / pathology; Liver Cirrhosis / blood; Liver Cirrhosis / diagnosis; Liver Cirrhosis / veterinary; Liver Diseases / blood; Liver Diseases / diagnosis; Liver Diseases / veterinary; Male; Necrosis; Prospective Studies
TL;DR:
Because of substantial variability among dogs, single measurements of IL‐6 and CCL2 have limited diagnostic utility for identifying fibrosis or necroinflammation, respectively, in dogs with various chronic liver diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 review
Epigenetic Modulation of CD8(+) T Cell Function in Lentivirus Infections: A Review
[Review of ]. VIRUSES-BASEL, 10(5).
author keywords: CD8(+) T cells; T regulatory cells; CD8(+) T cell dysfunction; epigenetics; lentiviral infections; feline immunodeficiency virus; simian immunodeficiency virus; human immunodeficiency virus
MeSH headings : Animals; CD8-Positive T-Lymphocytes / immunology; Cats; Cytokines / immunology; Epigenesis, Genetic; HIV Infections / immunology; Humans; Immunodeficiency Virus, Feline; Lentivirus Infections / immunology; Lentivirus Infections / veterinary; Lymphocyte Activation; Simian Immunodeficiency Virus; T-Lymphocytes, Regulatory / immunology; Viremia / veterinary
TL;DR:
Using the feline immunodeficiency virus (FIV) model for lentiviral persistence, it is demonstrated that CD8+ T cells exhibit epigenetic changes such as DNA demethylation during the course of infection as compared to uninfected cats and epigenetic modulation reduces Foxp3 binding to these promoter regions.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2018 journal article
Differential attenuation of Marek's disease virus-induced tumours and late-Marek's disease virus-induced immunosuppression
JOURNAL OF GENERAL VIROLOGY, 99(7), 927–936.
author keywords: Marek's disease virus; immunosuppression; virulence; meq; MHC-I
MeSH headings : Animals; Antibodies, Viral / biosynthesis; Carcinogenesis / genetics; Carcinogenesis / immunology; Carcinogenesis / pathology; Chickens; Female; Herpesvirus 1, Gallid / genetics; Herpesvirus 1, Gallid / immunology; Herpesvirus 1, Gallid / pathogenicity; Herpesvirus 2, Gallid / genetics; Herpesvirus 2, Gallid / immunology; Herpesvirus 2, Gallid / pathogenicity; Immunity, Humoral / drug effects; Immunologic Deficiency Syndromes / genetics; Immunologic Deficiency Syndromes / immunology; Immunologic Deficiency Syndromes / veterinary; Immunologic Deficiency Syndromes / virology; Lymphoma / genetics; Lymphoma / immunology; Lymphoma / veterinary; Lymphoma / virology; Marek Disease / genetics; Marek Disease / immunology; Marek Disease / pathology; Marek Disease / virology; MicroRNAs / genetics; MicroRNAs / immunology; RNA, Viral / genetics; RNA, Viral / immunology; Species Specificity; Viral Vaccines / administration & dosage; Virulence
TL;DR:
It is suggested that the immunosuppressive ability of MDV might follow a continuous spectrum and only the most virulent MDVs can overcome a certain threshold level and induce clinical MDV-IS in the ILT model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
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