Works Published in 2020
Displaying works 1 - 20 of 188 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2020 article
Genetic relatedness of multidrug resistant Escherichia coli isolated from humans, chickens and poultry environments
AWORH, M. A. B. E. L. K. A. M. W. E. L. I., Kwaga, J. K. P., Hendriksen, R. S., Okolocha, E. C., & Thakur, S. (2020, November 5).
aricjournal.biomedcentral.com (publisher PDF)
Source: ORCID
Added: September 21, 2023
2020 article
Genetic relatedness of multidrug resistant Escherichia coli isolated from humans, chickens and poultry environments
Aworh, M. K., Kwaga, J. K. P., Hendriksen, R. S., Okolocha, E. C., & Thakur, S. (2020, June 23).
Source: ORCID
Added: September 21, 2023
2020 article
Vesicular and Extravesicular Protein Signatures From the Airspaces of Ozone-Exposed Mice Reflect Muco-Inflammatory Disturbances.
Choudhary, I., Vo, T., Paudel, K., Gupta, R., Kesimer, M., Patial, S., & Saini, Y. (2020, December).
TL;DR:
This study identified exosomal, secretory, and cell-specific proteins and biological pathways following sub-chronic exposure of mice to ozone, indicating the cellular sources of the proteins that are ferried in the exosomes upon ozone-induced lung injury.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2020 journal article
Tristetraprolin Overexpression in Non-hematopoietic Cells Protects Against Acute Lung Injury in Mice.
Frontiers in Immunology.
MeSH headings : Acute Lung Injury / chemically induced; Acute Lung Injury / prevention & control; Alveolar Epithelial Cells / metabolism; Animals; Bone Marrow Transplantation; Bronchoalveolar Lavage Fluid / chemistry; Bronchoalveolar Lavage Fluid / cytology; Chemotaxis, Leukocyte; Cytokines / physiology; Endothelial Cells / metabolism; Female; Fibroblasts / metabolism; Lipopolysaccharides / toxicity; Male; Mice; Mice, Knockout; Neutrophil Infiltration; Neutrophils / immunology; Radiation Chimera; Tristetraprolin / biosynthesis; Tristetraprolin / deficiency; Tristetraprolin / genetics; Tristetraprolin / physiology; Up-Regulation
TL;DR:
It is suggested that non-HPCs-specific overexpression of TTP within the lungs protects against ALI via downregulation of neutrophil chemoattractants and reduction in neutrophilic infiltration.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2020 journal article
The Tristetraprolin Family of RNA-Binding Proteins in Cancer: Progress and Future Prospects.
Cancers, 6.
TL;DR:
The various hallmark molecular traits of cancers that are reported to be regulated by the tristetraprolin family of RNA-binding proteins are summarized and the role of the TTP family RBPs in the regulation of trait-associated mRNA targets in relevant cancer types/cell lines is emphasized.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2020 journal article
The Innate Lymphoid System Is a Critical Player in the Manifestation of Mucoinflammatory Airway Disease in Mice.
Journal of Immunology (Baltimore, Md. : 1950), 9.
MeSH headings : Animals; Cells, Cultured; Cystic Fibrosis / immunology; Disease Models, Animal; Epithelial Cells / metabolism; Epithelial Cells / pathology; Epithelial Sodium Channels / genetics; Homeodomain Proteins / genetics; Humans; Immunity, Innate; Inflammation / immunology; Metaplasia; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mucin-5B / genetics; Mucin-5B / metabolism; Respiratory Tract Diseases / immunology; Up-Regulation
TL;DR:
Collectively, these data indicate that, in the context of airway mucus obstruction, the adaptive immune system suppresses antibacterial macrophage activation, whereas the innate lymphoid system contributes to MCM, mucin production, and mucus obstruct.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2020 article
Ozone exposure upregulates the expression of host susceptibility protein TMPRSS2 to SARS-CoV-2
Vo, T., Paudel, K., Choudhary, I., Patial, S., & Saini, Y. (2020, November).
TL;DR:
The data indicate that the unhealthy levels of ozone in the environment may predispose individuals to severe SARS-CoV-2 infection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2020 journal article
Lung macrophages: current understanding of their roles in Ozone-induced lung diseases.
Critical Reviews in Toxicology, 4.
MeSH headings : Air Pollutants / toxicity; Air Pollution / statistics & numerical data; Animals; Humans; Lung / physiopathology; Lung Diseases / epidemiology; Lung Diseases / etiology; Macrophages / drug effects; Macrophages / physiology; Ozone / toxicity; United States
TL;DR:
There is a vital need for additional policy-relevant scientific information, including mechanistic studies to further define the role of macrophages in response to O3, and a comprehensive list of currently known macrophage-specific roles in O3-induced lung diseases is included in this review.
(via Semantic Scholar)
Source: ORCID
Added: August 2, 2023
2020 journal article
Compartment-specific transcriptomics of ozone-exposed murine lungs reveals sex- and cell type-associated perturbations relevant to mucoinflammatory lung diseases.
American Journal of Physiology. Lung Cellular and Molecular Physiology, 1.
Source: ORCID
Added: August 2, 2023
2020 journal article
Ablation of IL-33 Suppresses <i>Th2</i> Responses but Is Accompanied by Sustained Mucus Obstruction in the <i>Scnn1b</i> Transgenic Mouse Model.
Journal of Immunology (Baltimore, Md. : 1950), 3.
MeSH headings : Animals; Bronchoalveolar Lavage Fluid / cytology; Bronchoalveolar Lavage Fluid / immunology; Cystic Fibrosis / diagnosis; Cystic Fibrosis / genetics; Cystic Fibrosis / immunology; Cystic Fibrosis / pathology; Disease Models, Animal; Eosinophils / immunology; Eosinophils / metabolism; Epithelial Sodium Channels / genetics; Humans; Interleukin-33 / genetics; Interleukin-33 / metabolism; Lung / cytology; Lung / immunology; Lung / pathology; Mice; Mice, Knockout; Mice, Transgenic; Mucin 5AC / metabolism; Mucus / immunology; Mucus / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / immunology; Respiratory Mucosa / metabolism; Th2 Cells / immunology; Th2 Cells / metabolism
TL;DR:
Although IL- 33 modulates Th2 inflammatory responses and MUC5AC protein production, mucus obstruction is not dependent on IL-33, and histological features, including subepithelial airway inflammation and alveolar space enlargement, were somewhat exaggerated inIL-33KO/Tg+ mice.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: August 2, 2023
2020 journal article
Cases of high mortality in cull sows and feeder pigs associated with Streptococcus equi subsp. zooepidemicus septicemia
Journal of Veterinary Diagnostic Investigation.
MeSH headings : Animals; Female; Genotype; Ohio / epidemiology; Phylogeny; Sepsis / microbiology; Sepsis / mortality; Sepsis / veterinary; Streptococcal Infections / complications; Streptococcal Infections / microbiology; Streptococcal Infections / mortality; Streptococcal Infections / veterinary; Streptococcus equi / classification; Streptococcus equi / isolation & purification; Sus scrofa; Swine; Swine Diseases / microbiology; Swine Diseases / mortality; Tennessee / epidemiology
TL;DR:
The cause of these high mortality events in swine was S. zooepidemicus septicemia, and isolates from Ohio and Tennessee are concluded to be in genotype VI.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: July 6, 2023
2020 journal article
A model of respiratory syncytial virus (RSV) infection of infants in newborn lambs
Cell and Tissue Research, 380(2), 313–324.
Contributors: P. Sitthicharoenchai* , S. Alnajjar* & M. Ackermann
MeSH headings : Animals; Animals, Newborn; Disease Models, Animal; Humans; Respiratory Syncytial Virus Infections / diagnosis
TL;DR:
A comprehensive description of anatomical and immunological similarities between ovine and human lungs along with comparison of pulmonary changes and immune responses with RSV infection makes the newborn lamb an effective model for investigating key aspects of RSV infections in infants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: July 6, 2023
2020 journal article
Genetic characterization of Streptococcus equi subspecies zooepidemicus associated with high swine mortality in the United States
Transboundary and Emerging Diseases, 6.
MeSH headings : Animals; DNA, Bacterial / genetics; Disease Outbreaks / veterinary; Genome, Bacterial / genetics; Streptococcal Infections / microbiology; Streptococcal Infections / mortality; Streptococcal Infections / veterinary; Streptococcus equi / genetics; Streptococcus equi / isolation & purification; Streptococcus equi / pathogenicity; Swine; Swine Diseases / microbiology; Swine Diseases / mortality; United States / epidemiology; Virulence / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: July 6, 2023
2020 journal article
The PRRSV-Specific Memory B Cell Response Is Long-Lived in Blood and Is Boosted During Live Virus Re-exposure
Frontiers in Immunology, 11.
MeSH headings : Animals; Antibodies, Neutralizing / blood; Antibodies, Viral / blood; B-Lymphocytes / immunology; Immunologic Memory / immunology; Porcine respiratory and reproductive syndrome virus / immunology; RNA, Viral / blood; Swine; Vaccination; Viral Nonstructural Proteins / immunology; Viral Vaccines / immunology
TL;DR:
The creation and validation of a PRRSV nsp7-specific B cell tetramer now facilitates the ability to detect very rare memory B cells and thus define the memory response of the pig and answers key questions involved in regional specialization of the immune response following intramuscular inoculation ofPRRSV MLV.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: ORCID, Crossref
Added: July 3, 2023
2020 journal article
Establishment and characterization of a porcine B cell lymphoma cell line
Experimental Cell Research, 390(2), 111986.
MeSH headings : Animals; Antigens, CD / genetics; Antigens, CD / immunology; Apoptosis; B-Lymphocytes / immunology; B-Lymphocytes / pathology; Biomarkers, Tumor / genetics; Biomarkers, Tumor / immunology; Cell Line, Tumor; Cell Lineage / genetics; Cell Lineage / immunology; Cell Movement; Cell Proliferation; Cell Separation / methods; Founder Effect; Gene Expression Profiling; Humans; Lymph Nodes / immunology; Lymph Nodes / pathology; Lymphoma, B-Cell / genetics; Lymphoma, B-Cell / immunology; Lymphoma, B-Cell / pathology; PAX5 Transcription Factor / genetics; PAX5 Transcription Factor / immunology; Proto-Oncogene Proteins c-bcl-6 / genetics; Proto-Oncogene Proteins c-bcl-6 / immunology; Spleen / immunology; Spleen / pathology; Swine; Transcriptome
TL;DR:
These new Porcine B cell lymphoma cell lines will be a valuable resource for more in-depth cellular investigations into the porcine immune system and cancer, as well as providing a potential tool for the growth of lymphotropic viruses of pigs and humans.
(via Semantic Scholar)
Source: ORCID
Added: July 3, 2023
2020 journal article
Comparative Sequence Analysis of Historic and Current Porcine Rotavirus C Strains and Their Pathogenesis in 3-Day-Old and 3-Week-Old Piglets
Frontiers in Microbiology, 11.
TL;DR:
It is confirmed that these current, genetically heterogeneous PRVC strains possess distinct pathobiological characteristics that may contribute to the increased prevalence of PRVC diarrhea in neonatal suckling piglets.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(OpenAlex)
Source: ORCID
Added: July 3, 2023
2020 journal article
Extraskeletal chondrosarcoma in the tongue of a dog: case report and retrospective analysis of 236 tongue masses (2011–2019)
Journal of Veterinary Diagnostic Investigation, 32(3), 440–443.
MeSH headings : Animals; Chondrosarcoma / pathology; Chondrosarcoma / veterinary; Dog Diseases / pathology; Dogs; Male; Neoplasms, Connective and Soft Tissue / pathology; Neoplasms, Connective and Soft Tissue / veterinary; Retrospective Studies; Tongue Neoplasms / pathology; Tongue Neoplasms / veterinary
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: June 8, 2023
2020 journal article
Surveillance system assessment in Guinea: Training needed to strengthen data quality and analysis, 2016
PLOS ONE, 15(6), e0234796.
Ed(s): J. Schieffelin
MeSH headings : Community Health Planning / statistics & numerical data; Data Accuracy; Disease Outbreaks / statistics & numerical data; Epidemiological Monitoring; Guinea; Hemorrhagic Fever, Ebola / epidemiology; Humans; Public Health / education; Research Design
TL;DR:
Assessment findings suggest low sensitivity of the case-based disease surveillance system in Boffa, and recommend additional training and support to improve surveillance data quality and enhance Guinean public health workforce capacity to use these data.
(via Semantic Scholar)
Source: ORCID
Added: May 24, 2023
2020 journal article
Modeling Infectious Diseases in Healthcare Network (MInD-Healthcare) Framework for Describing and Reporting Multidrug-resistant Organism and Healthcare-Associated Infections Agent-based Modeling Methods
Clinical Infectious Diseases, 3.
MeSH headings : Communicable Diseases / epidemiology; Delivery of Health Care; Drug Resistance, Multiple, Bacterial; Humans; Reproducibility of Results; Systems Analysis
TL;DR:
The MInD-Healthcare framework provides a standardized way of describing and reporting models thereby instilling confidence in the reproducibility and generalizability of such models and will improve the quality of evidence generated utilizing these models.
(via Semantic Scholar)
Source: ORCID
Added: May 24, 2023
2020 journal article
Mitigating the Risk of Infectious Diseases Among Rural Drug Users in Western North Carolina: Results of the Southern Appalachia Test, Link, Care (SA‐TLC) Health Care Provider Survey
The Journal of Rural Health, 36(2), 208–216.
MeSH headings : Drug Users; HIV Infections / epidemiology; HIV Infections / prevention & control; Health Personnel; Hepatitis C / epidemiology; Hepatitis C / prevention & control; Humans; North Carolina / epidemiology; Opioid-Related Disorders / epidemiology; Prevalence; Risk Factors; Surveys and Questionnaires
TL;DR:
The authors' findings provide insights to inform health infrastructure improvement and to inform strategies for preventing injection drug use (IDU)-associated outbreaks of bloodborne infectious diseases in southern Appalachia.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: May 24, 2023
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