Works Published in 2021

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Displaying works 181 - 200 of 246 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

Neuromechanics and Energetics of Walking With an Ankle Exoskeleton Using Neuromuscular-Model Based Control: A Parameter Study

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 9.

By: B. Shafer*, S. Philius n, R. Nuckols*, J. McCall n, A. Young* & G. Sawicki*

author keywords: powered ankle exoskeleton; neuromuscular model; locomotion neuromechanics; human walking; muscle electromyography; metabolic energy cost; plantarflexor muscle-tendon mechanics
TL;DR: An ankle exoskeleton controller is developed that uses a neuromuscular model (NMM) comprised of a Hill type musculotendon driven by a simple positive force feedback reflex loop to capture the adaptive behavior of the human plantarflexors during natural gait. (via Semantic Scholar)
Source: Web Of Science
Added: May 10, 2021

2021 journal article

QUANTIFYING THE EFFECT OF ABDOMINAL BODY WALL ON IN SITU PEAK RAREFACTION PRESSURE DURING DIAGNOSTIC ULTRASOUND IMAGING

ULTRASOUND IN MEDICINE AND BIOLOGY, 47(6), 1548–1558.

author keywords: Mechanical index; In situ pressure; Tissue harmonic imaging; Measurement techniques; Abdominal ultrasound; Simulation
MeSH headings : Abdomen / diagnostic imaging; Abdominal Wall; Diagnostic Errors; Imaging, Three-Dimensional; Phantoms, Imaging; Pressure; Ultrasonography / methods
TL;DR: 3-D non-linear ultrasound simulations and experimental measurements were used to estimate the range of in situ pressures that can occur during transcutaneous abdominal imaging and to identify the sources of error when estimating in situ peak rarefaction pressures (PRPs) using linear derating, as specified by the mechanical index (MI) guideline. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: May 10, 2021

2021 journal article

Environmental Context Prediction for Lower Limb Prostheses With Uncertainty Quantification

IEEE TRANSACTIONS ON AUTOMATION SCIENCE AND ENGINEERING, 18(2), 458–470.

By: B. Zhong n, R. Silva n, M. Li n, H. Huang n & E. Lobaton n

Contributors: B. Zhong n, R. Silva n, M. Li n, H. Huang n & E. Lobaton n

author keywords: Uncertainty; Neural networks; Bayes methods; Measurement uncertainty; Cameras; Microsoft Windows; Bayesian neural network (BNN); environmental context prediction; prosthesis; uncertainty quantification
TL;DR: A novel vision-based context prediction framework for lower limb prostheses to simultaneously predict human’s environmental context for multiple forecast windows by leveraging the Bayesian neural networks (BNNs) and producing a calibrated predicted probability for online decision-making. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: May 10, 2021

2021 journal article

Microphysiological System for High-Throughput Computer Vision Measurement of Microtissue Contraction

ACS SENSORS, 6(3), 985–994.

author keywords: high throughput; 3D culture; tissue function; tissue contraction; computer vision
MeSH headings : Computers; Fibroblasts; High-Throughput Screening Assays; Humans; Image Processing, Computer-Assisted
TL;DR: An inexpensive, versatile, high-throughput platform to measure microtissue contraction in a 96-well plate configuration using one-step batch imaging and an algorithm uses pixel-based image analysis and computer vision techniques for the accurate multiwell quantification of positional changes in the optical microprobes caused by the contraction of the microtissues. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: May 10, 2021

2021 review

Static Force Measurement Using Piezoelectric Sensors

[Review of ]. JOURNAL OF SENSORS, 2021.

By: K. Kim n, J. Kim n, X. Jiang n & T. Kim*

TL;DR: A review of several static force sensing techniques using piezoelectric materials utilizing several unique parameters rather than just the surface charge produced by an applied force, including the resonance frequency, electrical impedance, decay time constant, and capacitance. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: April 26, 2021

2021 journal article

Exosome-eluting stents for vascular healing after ischaemic injury

NATURE BIOMEDICAL ENGINEERING, 5(10), 1174–1188.

By: S. Hu n, Z. Li n, D. Shen n, D. Zhu n, K. Huang n, T. Su n, P. Dinh n, J. Cores n, K. Cheng n

MeSH headings : Animals; Drug-Eluting Stents; Endothelial Cells; Endothelium, Vascular; Exosomes; Ischemia; Rats; Stents
TL;DR: It is shown that stents releasing exosomes derived from mesenchymal stem cells in the presence of reactive oxygen species enhance vascular healing in rats with renal ischaemia-reperfusion injury, promoting endothelial cell tube formation and proliferation, and impairing the migration of smooth muscle cells. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 26, 2021

2021 journal article

Multifractal roots of suprapostural dexterity

HUMAN MOVEMENT SCIENCE, 76.

author keywords: Biotensegrity; Center of mass; Center of pressure; Fractal; Hurst exponent; Postural sway
MeSH headings : Adult; Algorithms; Biomechanical Phenomena; Female; Fractals; Humans; Male; Models, Statistical; Motor Skills; Nonlinear Dynamics; Postural Balance / physiology; Posture / physiology; Regression Analysis; Young Adult
TL;DR: Findings indicate that the balance of SD within stable bounds may depend on a tendency for temporal correlations to self-correct across time, and are interpreted as part of the growing evidence that multifractal nonlinearity is a modeling strategy that resonates strongly with ecological-psychological approaches to perception and action. (via Semantic Scholar)
Source: Web Of Science
Added: April 19, 2021

2021 journal article

A 1.5-D Array for Acoustic Radiation Force (ARF)-Induced Peak Displacement-Based Tissue Anisotropy Assessment With a Row-Column Excitation Method

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(4), 1278–1287.

By: H. Wu n, M. Hossain n, H. Kim n, C. Gallippi n & X. Jiang n

author keywords: Transducers; Flexible printed circuits; Acoustics; Fabrication; Impedance; Anisotropic magnetoresistance; Muscles; 15-D array; acoustic radio forced impulse (ARFI); anisotropy; fractional anisotropy; peak displacement (PD); row-column excitation
MeSH headings : Acoustics; Anisotropy; Mechanical Phenomena; Phantoms, Imaging; Transducers
TL;DR: The results suggest that the array is capable of assessing DoA using PD ratio without physical rotation of the transducer and has the potential to reduce the misalignment errors for DoA assessment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 19, 2021

2021 journal article

Cell-Laden Nanocellulose/Chitosan-Based Bioinks for 3D Bioprinting and Enhanced Osteogenic Cell Differentiation

ACS APPLIED BIO MATERIALS, 4(3), 2342–2353.

author keywords: chitosan-based hydrogel; cellulose nanocrystal; bioink; osteogenic differentiation; bioprinting
MeSH headings : 3T3 Cells; Animals; Biocompatible Materials / chemistry; Biocompatible Materials / pharmacology; Bioprinting; Cell Differentiation / drug effects; Cells, Cultured; Cellulose / chemistry; Cellulose / pharmacology; Chitosan / chemistry; Chitosan / pharmacology; Ink; Materials Testing; Mice; Nanoparticles / chemistry; Osteogenesis / drug effects; Particle Size
TL;DR: The versatility of this CNCs-incorporated chitosan hydrogel makes it attractive as a bioink for 3D bioprinting to engineer scaffolds for bone tissue engineering and other therapeutic applications. (via Semantic Scholar)
Source: Web Of Science
Added: April 19, 2021

2021 journal article

Textile-Based Pressure Sensors for Monitoring Prosthetic-Socket Interfaces

IEEE SENSORS JOURNAL, 21(7), 9413–9422.

author keywords: Sensors; Sensor arrays; Sensor systems; Sockets; Monitoring; Data collection; Capacitive sensors; Pressure sensors; capacitive sensors; sensor arrays; body system networks; sensor systems and applications; textiles; wearable sensors; flexible electronics; prosthetics
TL;DR: This work presents a capacitive pressure sensor fabricated through a simple, and scalable sewing process using commercially available conductive yarns and textile materials that provides a soft, flexible, and comfortable sensing system for monitoring the inner socket environment (ISE). (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 19, 2021

2021 journal article

Formation of self-organized nano- and micro-diamond rings

MATERIALS RESEARCH LETTERS, 9(7), 300–307.

author keywords: Nanodiamond ring; self-organized nanodiamonds; Q-carbon
Source: Web Of Science
Added: April 19, 2021

2021 journal article

Using Reinforcement Learning to Estimate Human Joint Moments From Electromyography or Joint Kinematics: An Alternative Solution to Musculoskeletal-Based Biomechanics

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 143(4).

By: W. Wu n, K. Saul n & H. Huang n

Contributors: W. Wu n, K. Saul n & H. Huang n

MeSH headings : Electromyography
TL;DR: This study serves as a proof of concept that an RL approach can assist in biomechanical analysis and human-machine interface applications by deriving joint moments from kinematic or EMG data. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: April 19, 2021

2021 journal article

Sirtuin 6 (SIRT6) regulates redox homeostasis and signaling events in human articular chondrocytes

FREE RADICAL BIOLOGY AND MEDICINE, 166, 90–103.

By: J. Collins*, M. Kapustina*, J. Bolduc*, J. Pike*, B. Diekman n, K. Mix*, S. Chubinskaya*, E. Eroglu* ...

author keywords: Sirtuin; Aging; Oxidative stress; Antioxidant; Redox signaling; Osteoarthritis
MeSH headings : Aged; Animals; Biological Phenomena; Cartilage, Articular / metabolism; Chondrocytes; Homeostasis; Humans; Hydrogen Peroxide / metabolism; Mice; Oxidation-Reduction; Oxidative Stress; Sirtuins / genetics; Sirtuins / metabolism
TL;DR: It is demonstrated that SIRT6 activity is altered with age and oxidative stress conditions associated with aging, and contributes to chondrocyte redox homeostasis by regulating specific members of the Prx catalytic cycle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 12, 2021

2021 journal article

Patterned surfaces with the controllable drug doses using inkjet printing

JOURNAL OF MATERIALS RESEARCH, 36(19), 3865–3876.

By: S. Azizi Machekposhti n, B. Zhang n, R. Sachan n, L. Vanderwal*, S. Stafslien* & R. Narayan n

author keywords: Inkjet printing; Controllable drug doses; Amphotericin B; Azithromycin
TL;DR: The results indicate that piezoelectric inkjet printing may be useful for loading gauze with both antibacterial and antifungal pharmacologic agents with poor solubility in aqueous solutions for the treatment of mixed wounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 12, 2021

2021 journal article

Preganglionic and Postganglionic Brachial Plexus Birth Injury Effects on Shoulder Muscle Growth

JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 46(2).

By: N. Dixit n, C. McCormick n, E. Warren n, J. Cole n & K. Saul n

author keywords: Brachial plexus birth injury; contractures; muscle mass; range of motion; sarcomere length
MeSH headings : Animals; Birth Injuries / complications; Brachial Plexus / injuries; Brachial Plexus Neuropathies; Muscle, Skeletal; Range of Motion, Articular; Rats; Rats, Sprague-Dawley; Shoulder; Shoulder Joint
TL;DR: The findings suggest that the presence of contracture does not derive from restricted longitudinal muscle growth alone, but also depends on the extent of muscle mass loss occurring simultaneously after the injury. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: April 12, 2021

2021 journal article

Emerging biofabrication approaches for gastrointestinal organoids towards patient specific cancer models

CANCER LETTERS, 504, 116–124.

author keywords: Bioengineering; Organ on a chip; Self-assembly; Externally driven assembly; Personalized medicine
MeSH headings : Cell Differentiation; Gastrointestinal Tract / cytology; Humans; Models, Biological; Organoids / cytology; Precision Medicine; Tissue Engineering / methods
TL;DR: Development in three-dimensional (3D) artificial cell constructs to model gastrointestinal dynamics towards cancer diagnosis and the main challenges and possible risks regarding the potential translation of gastrointestinal organoids from laboratory settings to patient-specific models in clinical applications are outlined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 5, 2021

2021 journal article

Polyethylenimine-mediated controlled synthesis of Prussian blue-gold nanohybrids for biomedical applications

JOURNAL OF BIOMATERIALS APPLICATIONS, 36(1), 26–35.

author keywords: Prussian blue nanoparticles; gold nanoparticles; polyethylenimine; synchronous fluorescence spectroscopy; resonance Rayleigh scattering spectroscopy; non-enzymatic selective sensing
MeSH headings : Ferrocyanides / chemistry; Gold / chemistry; Metal Nanoparticles / chemistry; Polyethyleneimine / chemistry; Polymers; Spectrometry, Fluorescence / methods
TL;DR: It was shown that PEI-protected polycrystalline PBNPs can be synthesized in an acidic medium from the precursor potassium ferricyanide [K3Fe(CN)6] at 60 °C, and PEI concentration-dependent enhancement/quenching of fluorescence/resonance Rayleigh scattering was useful for non-enzymatic detection of serum glucose levels. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 5, 2021

2021 journal article

Synthetic Platelet Microgels Containing Fibrin Knob B Mimetic Motifs Enhance Clotting Responses

ADVANCED THERAPEUTICS, 4(5).

By: S. Nandi n, E. Mihalko n, K. Nellenbach n, M. Castaneda n, J. Schneible n, M. Harp*, H. Deal n, M. Daniele n ...

author keywords: bleeding; Clotting; fibrin; hemostasis; microgel
TL;DR: Soft microgels decorated with the peptide AHRPYAAK are found to significantly increase clot density in vitro and decrease bleeding in a rodent trauma model in vivo, indicating that FAMCYs are capable of recapitulating the platelet‐mimetic properties of previous designs while utilizing a less costly, more translational design. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: April 5, 2021

2021 journal article

Electronic Point Spread Function Rotation Using a Three-Row Transducer for ARFI-Based Elastic Anisotropy Assessment: In Silico and Experimental Demonstration

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(3), 632–646.

author keywords: Transducers; Finite element analysis; Mechanical factors; Acoustics; Muscles; Anisotropic magnetoresistance; Direction-of-arrival estimation; Acoustic radiation force impulse (ARFI); anisotropy; muscle; peak displacement (PD); shear wave elasticity imaging (SWEI); transversely isotropic (TI) material
MeSH headings : Animals; Anisotropy; Computer Simulation; Elasticity Imaging Techniques; Electronics; Reproducibility of Results; Rotation; Swine; Transducers
TL;DR: Evaluated results suggest that ARFI-based DoA assessment can be achieved without manual transducer rotation using a three-row transducers capable of electronically rotating PSFs by 63°. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: April 5, 2021

2021 journal article

The combination of mitogenic stimulation and DNA damage induces chondrocyte senescence

OSTEOARTHRITIS AND CARTILAGE, 29(3), 402–412.

author keywords: SA-beta-gal; DNA damage; Osteoarthritis; Aging; TGF- beta 1; bFGF
MeSH headings : Animals; Ankle Joint; Cartilage, Articular / cytology; Cartilage, Articular / drug effects; Cartilage, Articular / metabolism; Cellular Senescence / drug effects; Cellular Senescence / genetics; Chemokine CCL2 / drug effects; Chemokine CCL2 / genetics; Chondrocytes / drug effects; Chondrocytes / metabolism; Cyclin-Dependent Kinase Inhibitor p16 / drug effects; Cyclin-Dependent Kinase Inhibitor p16 / metabolism; DNA Damage / genetics; Fibroblast Growth Factor 2 / pharmacology; Gene Expression / drug effects; Histones / drug effects; Histones / metabolism; Horses; Humans; In Vitro Techniques; Inflammation / genetics; Insulin-Like Growth Factor Binding Protein 3 / drug effects; Insulin-Like Growth Factor Binding Protein 3 / genetics; Interleukin-6 / genetics; Matrix Metalloproteinase 13 / drug effects; Matrix Metalloproteinase 13 / genetics; Mitogens / pharmacology; Stifle; Transforming Growth Factor beta1 / pharmacology; beta-Galactosidase / drug effects; beta-Galactosidase / metabolism
TL;DR: Treatment of cartilage explants with mitogenic stimuli in the context of cellular damage reliably induces high levels of SA-β-gal activity and other senescence markers, which provides a physiologically relevant model system to investigate the mechanisms of senescences induction. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: March 29, 2021

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