Works Published in 2022

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Displaying works 181 - 200 of 212 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2022 journal article

Loading during Midstance of Gait Is Associated with Magnetic Resonance Imaging of Cartilage Composition Following Anterior Cruciate Ligament Reconstruction

CARTILAGE, 13(1).

author keywords: biomechanics; vertical ground reaction force; posttraumatic osteoarthritis; T1 rho; ACL
MeSH headings : Adolescent; Adult; Anterior Cruciate Ligament Reconstruction / methods; Cartilage, Articular / pathology; Female; Gait; Humans; Knee Joint / diagnostic imaging; Knee Joint / surgery; Magnetic Resonance Imaging / methods; Male; Young Adult
TL;DR: Biomechanical gait profiles that include greater vGRF during midstance are associated with MRI estimates of lesser proteoglycan density in the MFC, suggesting inability to unload the ACLR limb during midstances may be linked to joint tissue changes associated with PTOA development. (via Semantic Scholar)
Source: Web Of Science
Added: February 21, 2022

2022 journal article

Illumination angle correction during image acquisition in light-sheet fluorescence microscopy using deep learning

BIOMEDICAL OPTICS EXPRESS, 13(2), 888–901.

TL;DR: This study provides a framework that can correct the angle of the light-sheet and improve the overall image quality in high-resolution LSFM 3D image acquisition. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 14, 2022

2022 journal article

An Analysis of Sonothrombolysis and Cavitation for Retracted and Unretracted Clots Using Microbubbles Versus Low-Boiling-Point Nanodroplets

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 69(2), 711–719.

author keywords: Ultrasonic imaging; Acoustics; Medical treatment; Frequency control; Coagulation; Transducers; Surface treatment; Cavitation; microbubble (MB); nanodroplet (ND); retracted clot; sonothrombolysis; thrombosis
MeSH headings : Aged; Blood Coagulation; Humans; Microbubbles; Thrombosis / diagnostic imaging; Thrombosis / therapy; Ultrasonic Therapy / methods
TL;DR: It is concluded that ND-mediated sonothrombolysis outperforms MB-mediated therapy regardless of clot retraction, and this advantage of ND- mediated cavitation is emphasized for retracted clots. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 14, 2022

2022 journal article

Inferring Human-Robot Performance Objectives During Locomotion Using Inverse Reinforcement Learning and Inverse Optimal Control

IEEE ROBOTICS AND AUTOMATION LETTERS, 7(2), 2549–2556.

Contributors: W. Liu n, J. Zhong*, R. Wu*, B. Fylstra n, J. Si* & H. Huang n

author keywords: Learning from demonstration; reinforcement learning; wearable robotics
TL;DR: This study proposes a new inverse approach from observed human-robot walking behavior to infer a human- robot collective performance objective represented in a quadratic form and introduces a new tool to the field of wearable lower limb robots. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 14, 2022

2022 article

Translation of 3D printed materials for medical applications

Bandyopadhyay, A., Bose, S., & Narayan, R. (2022, February 3). MRS BULLETIN.

author keywords: 3D Printing; Biomaterial; Devices; Additive manufacturing
TL;DR: This special issue reviews recent advances in translating 3D biomaterials and medical devices for metallic, ceramic, and polymeric devices, as well as bioprinting for organ and tissue engineering, along with regulatory issues in 3DP biommaterials. (via Semantic Scholar)
Source: Web Of Science
Added: February 14, 2022

2022 journal article

Evoked Tactile Feedback and Control Scheme on Functional Utility of Prosthetic Hand

IEEE ROBOTICS AND AUTOMATION LETTERS, 7(2), 1300–1307.

Contributors: L. Vargas*, H. Huang*, Y. Zhu n & X. Hu*

author keywords: Tactile sensation; transcutaneous nerve stimulation; prosthetic hand; functional task; haptic feedback
TL;DR: The findings reveal that non-invasively evoked tactile feedback could be used to effectively enable human-in-the-loop control of a prosthetic hand and can provide a platform to characterize the action-perception couplings during prosthetic control in order to improve user experience and system functionality. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: February 7, 2022

2022 journal article

Validation of a combined ultrasound and bioluminescence imaging system with magnetic resonance imaging in orthotopic pancreatic murine tumors

SCIENTIFIC REPORTS, 12(1).

By: J. Rojas*, J. Joiner*, B. Velasco n, K. Bautista n, A. Aji*, C. Moore*, N. Beaumont*, Y. Pylayeva-Gupta* ...

MeSH headings : Animals; Cell Line, Tumor; Disease Progression; Early Detection of Cancer / methods; High-Throughput Screening Assays; Magnetic Resonance Imaging; Mice, Inbred C57BL; Multimodal Imaging; Optical Imaging; Pancreatic Neoplasms / diagnostic imaging; Pancreatic Neoplasms / pathology; Predictive Value of Tests; Reproducibility of Results; Time Factors; Tumor Burden; Ultrasonography
TL;DR: It is concluded that combining BLI with robotic US offers an efficient screening tool for orthotopic tumor models, and offers complementary advantages of detection sensitivity and quantification accuracy, while mitigating individual technological weaknesses. (via Semantic Scholar)
Source: Web Of Science
Added: February 7, 2022

2022 article

Elucidating the combinatorial effect of substrate stiffness and surface viscoelasticity on cellular phenotype

Chester, D., Lee, V., Wagner, P., Nordberg, M., Fisher, M. B., & Brown, A. C. (2022, February 1). JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A.

By: D. Chester n, V. Lee n, P. Wagner n, M. Nordberg n, M. Fisher n & A. Brown n

author keywords: loss tangent; mechanotransduction; microgel; viscoelasticity
MeSH headings : Biocompatible Materials / chemistry; Hydrogels / chemistry; Hydrogels / pharmacology; Mechanotransduction, Cellular / physiology; Phenotype; Viscosity
TL;DR: A novel composite hydrogel system capable of decoupling and individually controlling both the bulk stiffness and surface viscoelasticity of the material by combining polyacrylamide gels with microgel thin films is characterized, allowing for a greater understanding of cellular mechanotransduction mechanisms than previously possible through current model material platforms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: February 7, 2022

2022 journal article

Multilayer microfluidic platform for the study of luminal, transmural, and interstitial flow

BIOFABRICATION, 14(2).

author keywords: microfluidics; vascular biology; interstitial flow; hemodynamics; biofluid mechanics; mechanotransduction
MeSH headings : Lymphatic Vessels; Microfluidics / methods; Stress, Mechanical
TL;DR: A multi-layer microfluidic platform (MμLTI-Flow) is introduced that enables the culture of engineered blood and lymphatic microvessels and independent control of blood, lymphatic, and IFPs and will provide for analysis of key fluid mechanical parameters and cellular mechanisms that contribute to diseases in which fluid imbalances play a role in progression, including lymphedema and solid cancer. (via Semantic Scholar)
Source: Web Of Science
Added: January 31, 2022

2022 article

Laser-patterned carbon coatings on flexible and optically transparent plastic substrates for advanced biomedical sensing and implant applications

Joshi, P., Riley, P. R., Denning, W., Shukla, S., Khosla, N., Narayan, J., & Narayan, R. (2022, January 13). JOURNAL OF MATERIALS CHEMISTRY C.

By: P. Joshi n, P. Riley n, W. Denning*, S. Shukla n, N. Khosla n, J. Narayan n, R. Narayan n

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 24, 2022

2022 journal article

Nanoparticle Delivery of miR-122 Inhibits Colorectal Cancer Liver Metastasis

CANCER RESEARCH, 82(1), 105–113.

By: H. Sendi*, M. Yazdimamaghani*, M. Hu*, N. Sultanpuram*, J. Wang*, A. Moody n, E. McCabe*, J. Zhang* ...

MeSH headings : Animals; Colorectal Neoplasms / complications; Colorectal Neoplasms / genetics; Humans; Liver Neoplasms / secondary; Mice; MicroRNAs / metabolism; Nanoparticles / metabolism; Neoplasm Metastasis; Tumor Microenvironment
TL;DR: Mechanistic studies revealed that delivery of miR-122 was associated with downregulation of key genes involved in metastatic and cancer inflammation pathways, including several proinflammatory factors, matrix metalloproteinases, and other extracellular matrix degradation enzymes, which makes the liver more conducive to antitumor immune response. (via Semantic Scholar)
Source: Web Of Science
Added: January 24, 2022

2022 journal article

Light-induced production of isobutanol and 3-methyl-1-butanol by metabolically engineered cyanobacteria

MICROBIAL CELL FACTORIES, 21(1).

By: S. Kobayashi*, S. Atsumi*, K. Ikebukuro*, K. Sode n & R. Asano*

author keywords: Biofuel; CcaS/CcaR two-component system; Cyanobacteria; Isobutanol; Light-regulated gene expression; Metabolic regulation; Synechocystis sp. PCC 6803; 3-methyl-1-butanol
MeSH headings : Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Butanols / metabolism; Light; Metabolic Engineering; Pentanols / metabolism; Photoreceptors, Microbial / genetics; Photoreceptors, Microbial / metabolism; Photosynthesis; Promoter Regions, Genetic; Synechocystis / genetics; Synechocystis / growth & development; Synechocystis / metabolism
TL;DR: It is found that the production of isobutanol and 3MB from carbon dioxide (CO 2) was induced under red and green light illumination and was substantially repressed under red light illumination alone. (via Semantic Scholar)
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2022 journal article

Restoring Carboxylates on Highly Modified Alginates Improves Gelation, Tissue Retention and Systemic Capture

ACTA BIOMATERIALIA, 138, 208–217.

By: C. Moody n, A. Brown n, N. Massaro n, A. Patel n, P. Agarwalla n, A. Simpson n, A. Brown n, H. Zheng n, J. Pierce n, Y. Brudno n

author keywords: Alginate; Click chemistry; Bioconjugation; Ionic cross-linking; Drug capture
UN Sustainable Development Goal Categories
Sources: Web Of Science, NC State University Libraries
Added: January 18, 2022

2022 article

Fused Ultrasound And Electromyography-Driven Neuromuscular Model To Improve Plantarflexion Moment Prediction Across Walking Speeds

Zhang, Q., Fragnito, N., Franz, J. R., & Sharma, N. (2022, January 11).

By: Q. Zhang n, N. Fragnito n, J. Franz n & N. Sharma n

UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: January 12, 2022

2022 journal article

Transcranial Neuromodulation Array With Imaging Aperture for Simultaneous Multifocus Stimulation in Nonhuman Primates

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 69(1), 261–272.

author keywords: Ultrasonic imaging; Neuromodulation; Brain modeling; Imaging; Focusing; Attenuation; Transducers; Customized array; focused ultrasound; neuromodulation; phase aberration correction; simultaneous stimulation; transcranial
MeSH headings : Animals; Brain / diagnostic imaging; Primates; Skull / diagnostic imaging; Transducers; Ultrasonic Therapy
TL;DR: Using 3-D Fullwave simulations, this work has designed an ultrasound neuromodulation array for nonhuman primates that can simultaneously focus on multiple targets and include an imaging aperture for additional functional imaging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 10, 2022

2022 journal article

Characterization of the Ultrasound Localization Microscopy Resolution Limit in the Presence of Image Degradation

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 69(1), 124–134.

author keywords: Image degradation; resolution; super-resolution; ultrasound localization microscopy (ULM)
MeSH headings : Computer Simulation; Microscopy; Ultrasonography
TL;DR: This work investigated the effects of three sources of image degradation on the resolution limit of ULM, and demonstrated the importance of phase aberration correction and clutter filtering in ULM postprocessing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 10, 2022

2022 article

Deep learning-based autofocus method enhances image quality in light-sheet fluorescence microscopy: publishers note (vol 12, pg 5214, 2021)

LI, C., Moatti, A., Zhang, X., Ghashghaei, H. T., & Greenbaum, A. (2022, January 1). BIOMEDICAL OPTICS EXPRESS, Vol. 13, pp. 373–373.

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 10, 2022

2022 journal article

Ultrasound Echogenicity as an Indicator of Muscle Fatigue during Functional Electrical Stimulation

SENSORS, 22(1).

Contributors: Q. Zhang n, A. Iyer n, K. Lambeth n, K. Kim* & N. Sharma n

author keywords: muscle fatigue; electrical stimulation; ankle joint; biomechanical phenomena; ultrasonography; linear models; nonlinear dynamics
MeSH headings : Electric Stimulation; Humans; Isometric Contraction; Muscle Contraction; Muscle Fatigue; Muscle, Skeletal; Ultrasonography
TL;DR: The findings in this study indicate that the US echogenicity signal is a computationally efficient signal that strongly represents FES-induced muscle fatigue and its potential real-time implementation to detect fatigue can facilitate an FES closed-loop controller design that considers the Fes- induced muscle fatigue. (via Semantic Scholar)
Sources: ORCID, Web Of Science, NC State University Libraries
Added: January 8, 2022

2022 journal article

In Vitro Evaluation of Miniaturized Amperometric Enzyme Sensor Based on the Direct Electron Transfer Principle for Continuous Glucose Monitoring

Journal of Diabetes Science and Technology, 1, 193229682110706.

By: Y. Inoue*, Y. Kusaka*, K. Shinozaki*, I. Lee n & K. Sode n

author keywords: FADGDH; direct electron transfer (DET); third-generation glucose sensor; continuous glucose monitoring (CGM)
MeSH headings : Humans; Acetaminophen; Biosensing Techniques / methods; Blood Glucose; Blood Glucose Self-Monitoring / methods; Electrodes; Electrons; Glucose; Glucose 1-Dehydrogenase
TL;DR: The amperometric response of the sensor showed a linear response to glucose concentration up to 500 mg/dL without significant change of the response over an 11-day continuous measurement, indicating the superb potential of the DET-type FADGDH-based sensor with the combination of a miniaturized integrated electrode. (via Semantic Scholar)
Source: ORCID
Added: January 7, 2022

2022 journal article

A Direct Comparison of Node and Element-Based Finite Element Modeling Approaches to Study Tissue Growth

JOURNAL OF BIOMECHANICAL ENGINEERING-TRANSACTIONS OF THE ASME, 144(1).

By: D. Howe n, N. Dixit n, K. Saul n & M. Fisher n

MeSH headings : Bone and Bones; Finite Element Analysis; Models, Biological
TL;DR: The importance of the choice of implementation approach for modeling growth is illustrated, a framework for converting models between implementation approaches is provided, and important considerations for comparing results in prior work and developing new models of tissue growth are highlighted. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 3, 2022

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