Works Published in 2014
Displaying works 21 - 40 of 140 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 conference paper
A discrete-time nonlinear estimator for an orthosis-aided gait
ASME 2014 Dynamic Systems and Control Conference, DSCC 2014, 1. http://www.scopus.com/inward/record.url?eid=2-s2.0-84929353401&partnerID=MN8TOARS
Contributors: A. Dani & N. Sharma
Source: ORCID
Added: August 12, 2021
2014 journal article
Macrophages Modulate Engineered Human Tissues for Enhanced Vascularization and Healing
Annals of Biomedical Engineering, 43(3), 616–627.
author keywords: Scaffold; Vascularization; Inflammatory response; Tissue engineering; Healing
MeSH headings : Animals; Humans; Inflammation / immunology; Macrophages / physiology; Neovascularization, Physiologic; Regeneration; Tissue Engineering; Tissue Scaffolds
TL;DR:
This work discusses here the cell–scaffold–bioreactor systems for harnessing the inflammatory response for enhanced tissue vascularization and healing and a new generation of “smart” tissue engineering systems designed to actively mediate tissue survival and function.
(via Semantic Scholar)
europepmc.org (repository)
Source: Crossref
Added: January 21, 2021
2014 journal article
Two-photon polymerization/micromolding of microscale barbs for medical applications
Journal of Adhesion Science and Technology, 28(3-4), 387–398.
author keywords: tissue barb; wound sealant; two-photon polymerization; micromolding; indirect rapid prototyping
TL;DR:
The results suggest that two-photon polymerization/micromolding is an indirect rapid prototyping approach that may be used for high-throughput replication of tissue barbs and other microstructured solid wound sealants.
(via Semantic Scholar)
Source: Crossref
Added: January 14, 2021
2014 journal article
MIP-based electrochemical protein profiling
Sensors and Actuators B: Chemical, 204, 88–95.
author keywords: Biosensors; Electrochemical protein detection; Molecularly imprinted polymers; Pattern recognition; Modified electrodes; Electronic tongue
Source: Crossref
Added: January 14, 2021
2014 journal article
Diagnostic Devices: Microneedle-Based Transdermal Sensor for On-Chip Potentiometric Determination of K+(Adv. Healthcare Mater. 6/2014)
Advanced Healthcare Materials, 3(6), 948–948.
Source: Crossref
Added: January 14, 2021
2014 journal article
A microfluidic device for thermal particle detection
Microfluidics and Nanofluidics, 17(5), 871–878.
author keywords: Microfluidics; Particle counting; Thermal
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Crossref
Added: December 21, 2020
2014 journal article
Functional properties of bone marrow-derived MSC-based engineered cartilage are unstable with very long-term in vitro culture
Journal of Biomechanics, 47(9), 2173–2182.
author keywords: Mesenchymal stem cells; Chondrogenesis; Three-dimensional culture; Cartilage; Mechanical properties
MeSH headings : Animals; Bone Marrow Cells / cytology; Cartilage / cytology; Cartilage / metabolism; Cattle; Cell Survival; Cells, Cultured; Chondrocytes / cytology; Chondrogenesis; Femur; Glycosaminoglycans / metabolism; Hydrogels; Mesenchymal Stem Cells / cytology; Sepharose; Tissue Engineering / methods; Tissue Scaffolds
TL;DR:
Data suggest that, even within a controlled in vitro environment that is conducive to chondrogenesis, there may be an innate instability in the MSC phenotype that is independent of scaffold composition, and may ultimately limit their application in functional cartilage repair.
(via Semantic Scholar)
Source: Crossref
Added: December 19, 2020
2014 journal article
Maximizing cartilage formation and integration via a trajectory-based tissue engineering approach
Biomaterials, 35(7), 2140–2148.
author keywords: Tissue engineering; Hyaluronic acid; Hydrogels; Cartilage; Integration; Maturation
MeSH headings : Animals; Cartilage / growth & development; Cattle; Tissue Engineering
TL;DR:
It is shown that integration to cartilage in-vitro is not correlated to the maturation state of TE constructs, but rather their maturation rate, providing a proof-of-concept for the use of TB-TE to enhance treatment outcomes following cartilage injury.
(via Semantic Scholar)
Source: Crossref
Added: December 19, 2020
2014 journal article
Reduced Tissue-Level Stiffness and Mineralization in Osteoporotic Cancellous Bone
Calcified Tissue International, 95(2), 125–131.
Contributors: G. Kim *, J. Cole* , A. Boskey*, S. Baker* & M. Meulen *
author keywords: Nanoindentation; Raman spectroscopy; Osteoporosis; Human trabecular bone
MeSH headings : Absorptiometry, Photon; Aged; Aged, 80 and over; Cadaver; Calcification, Physiologic / physiology; Female; Humans; Lumbar Vertebrae / diagnostic imaging; Lumbar Vertebrae / physiopathology; Middle Aged; Osteoporosis / diagnostic imaging; Osteoporosis / physiopathology
TL;DR:
Differences in tissue composition and mechanical properties with osteoporosis that could contribute to increased fragility in addition to changes in trabecular architecture and bone volume are found.
(via Semantic Scholar)
Sources: Crossref, ORCID
Added: December 11, 2020
2014 journal article
The development of an autonomous self-powered bio-sensing actuator
Sensors and Actuators B-Chemical, 196, 429–433.
Contributors: T. Hanashi*, T. Yamazaki *, H. Tanaka *, K. Ikebukuro *, W. Tsugawa * & K. Sode*
author keywords: Enzyme fuel cell; Autonomous; Sensing actuator; Flavin adenine dinucleotide-dependent glucose dehydrogenase; Self-powered; Drug delivery systems
TL;DR:
An autonomous, self-powered, sensing actuator that employs the principle of BioCapacitor as the core technology is reported, which demonstrates its potential for application as a drug delivery/pumping system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2014 journal article
THE 3RD GENERATION CGM SENSOR UTILIZING DIRECT ELECTRON TRANSFER PRINCIPLE
Diabetes Technology & Therapeutics, 16, A78–A79. http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000331218000205&KeyUID=WOS:000331218000205
Contributors: S. Sekimoto, K. Shinozaki, Y. Murase, Y. Kusaka, K. Kojima, W. Tsugawa, K. Sode
Source: ORCID
Added: October 9, 2020
2014 journal article
Study of the role of anaerobic metabolism in succinate production by Enterobacter aerogenes
Applied Microbiology and Biotechnology, 98(18), 7803–7813.
Contributors: Y. Tajima*, K. Kaida*, A. Hayakawa*, K. Fukui*, Y. Nishio *, K. Hashiguchi*, R. Fudou, K. Matsui *, Y. Usuda*, K. Sode*
author keywords: Enterobacter aerogenes; Succinate fermentation; Redox balance; Phosphoenolpyruvate carboxykinase; Ethanol dehydrogenase
TL;DR:
These single-gene knockout studies showed that the ethanol synthesis pathway serves as the dominant NADH re-oxidation pathway in this organism and showed the potential of bacteria-based succinate fermentation under weak acidic conditions.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2014 journal article
Simultaneous Improvement of Specificity and Affinity of Aptamers Against Streptococcus mutans by In Silico Maturation for Biosensor Development
Biotechnology and Bioengineering, 111(3), 454–461.
Contributors: N. Savory *, Y. Takahashi*, K. Tsukakoshi *, H. Hasegawa*, M. Takase*, K. Abe *, W. Yoshida *, S. Ferri*
author keywords: aptamers; Streptococcus mutans; Cell-SELEX; in silico maturation; flow-through test
MeSH headings : Aptamers, Nucleotide / isolation & purification; Biosensing Techniques / methods; Computer Simulation; Sensitivity and Specificity; Streptococcus mutans / isolation & purification
TL;DR:
A successful application of ISM of aptamers is demonstrated to simultaneously improve specificity and affinity for Streptococcus mutans with discovery of a core sequence, which was required to form a polymerized guanine quadruplex structure for target binding.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2014 journal article
Improving the Gene-Regulation Ability of Small RNAs by Scaffold Engineering in Escherichia coli
Acs Synthetic Biology, 3(3), 152–162.
Contributors: Y. Sakai*, K. Abe *, S. Nakashima*, W. Yoshida *, S. Ferri*, K. Sode* , K. Ikebukuro *
author keywords: attenuator; Hfq; post-transcriptional gene regulation; riboregulator; small RNA; transcriptional gene regulation
MeSH headings : Base Sequence; Escherichia coli / genetics; Gene Expression Regulation, Bacterial / genetics; Genetic Engineering / methods; Molecular Sequence Data; Mutation; Nucleic Acid Conformation; RNA, Small Untranslated / genetics; Synthetic Biology / methods
TL;DR:
Efficient gene regulation abilities of small RNAs are improved by directly fusing the natural Escherichia coli trans-encoded small RNA-derived scaffolds, including Hfq-binding and rho-independent transcription terminator sequences, to the 3' end of the smallRNAs that mediate RNA-based gene regulation.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2014 journal article
Engineering of a green-light inducible gene expression system in Synechocystis sp PCC6803
Microbial Biotechnology, 7(2), 177–183.
Contributors: K. Abe *, K. Miyake*, M. Nakamura*, K. Kojima*, S. Ferri*, K. Ikebukuro *, K. Sode*
MeSH headings : Artificial Gene Fusion; Bacterial Proteins / genetics; Gene Expression; Gene Expression Regulation, Bacterial / radiation effects; Genes, Reporter; Genetic Engineering; Genetics, Microbial / methods; Green Fluorescent Proteins / analysis; Green Fluorescent Proteins / genetics; Light; Promoter Regions, Genetic; Synechocystis / genetics; Synechocystis / radiation effects; Transcriptional Activation / radiation effects
TL;DR:
The constructed engineered green‐light sensing system resulted in about 40‐fold higher protein expression than with the wild‐type promoter with a high ON/OFF ratio under green‐ light illumination, which would be a useful genetic tool for controlling gene expression in the emergent cyanobacterial bioprocesses.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2014 journal article
Engineering glucose oxidase to minimize the influence of oxygen on sensor response
Electrochimica Acta, 126, 158–161.
Contributors: Y. Horaguchi*, S. Saito*, K. Kojima*, W. Tsugawa *, S. Ferri* & K. Sode*
author keywords: Biosensor; Glucose oxidase; Glucose dehydrogenase; Flavin adenine dinucleotide; Oxygen
TL;DR:
The rational amino acid substitution approach resulted in the construction of the Ser114Ala/Phe355Leu mutant, which has an 11-fold decrease in oxidase activity and 2.8-fold increase in dehydrogenase activity compared with wild-type GOx and was considerably less affected by oxygen than the wild- type GOx-based sensor at lower glucose concentrations.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2014 journal article
Electrochemical detection of pathogenic bacteria by using a glucose dehydrogenase fused zinc finger protein
Analytical Methods, 6(14), 4991–4994.
Contributors: J. Lee *, A. Tatsumi*, K. Abe *, W. Yoshida *, K. Sode* & K. Ikebukuro *
TL;DR:
An electrochemical detection system for pathogenic bacteria by utilizing a glucose dehydrogenase-fused zinc finger protein (ZF-GDH), which could detect PCR products electrochemically without the need for DNA probe hybridization is developed.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2014 journal article
Design of riboregulators for control of cyanobacterial (Synechocystis) protein expression
Biotechnology Letters, 36(2), 287–294.
Contributors: K. Abe *, Y. Sakai*, S. Nakashima*, M. Araki*, W. Yoshida *, K. Sode* , K. Ikebukuro *
author keywords: Biofuels; Cyanobacteria; Post-transcriptional gene regulation; Riboregulator; Synechocystis; Synthetic biology
MeSH headings : Bacterial Proteins / biosynthesis; Biotechnology / methods; Gene Expression Regulation, Bacterial; Metabolic Engineering / methods; Molecular Biology / methods; RNA / metabolism; Ribosomes / drug effects; Ribosomes / metabolism; Synechocystis / genetics; Synechocystis / metabolism
TL;DR:
R riboregulators, that one of the post-transcriptional regulators composed of RNAs, were constructed for controlling cyanobacterial protein expression and were effective in Synechocystis sp.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2014 journal article
A green-light inducible lytic system for cyanobacterial cells
Biotechnology For Biofuels, 7(1), (9 April 2014).
Contributors: K. Miyake*, K. Abe *, S. Ferri*, M. Nakajima*, M. Nakamura*, W. Yoshida *, K. Kojima*, K. Ikebukuro *, K. Sode*
author keywords: Cyanobacteria; Self-lysis; Two-component system; T4 bacteriophage; Synthetic biology
TL;DR:
The constructed green-light inducible lytic system was clearly induced by green- light illumination, resulting in lytic cells that released intracellular phycocyanin into the culture supernatant, suggesting a future possibility to construct photosynthetic genetically modified organisms that are unable to survive under sunlight exposure.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: ORCID
Added: October 9, 2020
2014 conference paper
Practical implementation of robust sensor interface for EMG pattern recognition for artificial arm control
Presented at the International Conference on Advanced Limb Prosthetics, Fredericton, New Brunswick, Canada.
Event: International Conference on Advanced Limb Prosthetics at Fredericton, New Brunswick, Canada on August 19-22, 2014
Source: NC State University Libraries
Added: September 27, 2020
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