Works Published in 2008
Displaying works 41 - 60 of 86 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2008 journal article
Biofuel cell system employing thermostable glucose dehydrogenase
Biotechnology Letters, 30(10), 1753–1758.
Contributors: J. Okuda-Shimazaki*, N. Kakehi*, T. Yamazaki *, M. Tomiyama* & K. Sode*
author keywords: biofuel cell; glucose dehydrogenase; direct electron transfer
MeSH headings : Bioelectric Energy Sources; Burkholderia cepacia / genetics; Catalysis; Enzyme Stability; Glucose 1-Dehydrogenase / genetics; Glucose 1-Dehydrogenase / metabolism; Recombinant Proteins / genetics; Recombinant Proteins / metabolism
TL;DR:
The results indicate the potential application of this thermostable glucose dehydrogenase for the construction of a compartment-less biofuel cell.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2008 journal article
Aptameric enzyme subunit for homogeneous DNA sensing
Biotechnology Letters, 30(2), 243–252.
Contributors: K. Ikebukuro *, W. Yoshida * & K. Sode*
author keywords: aptameric enzyme subunit; enzyme-inhibiting aptamer; homogeneous DNA sensing
MeSH headings : Aptamers, Nucleotide / pharmacology; Base Sequence; Biosensing Techniques; DNA / analysis; DNA / genetics; Humans; Molecular Sequence Data; Nucleic Acid Hybridization; Protein Subunits / antagonists & inhibitors; Protein Subunits / chemistry; Protein Subunits / metabolism; Thrombin / analysis; Thrombin / antagonists & inhibitors; Thrombin / genetics
TL;DR:
An aptameric enzyme subunit (AES) which can detect the DNA in a homogeneous solution that is composed of an enzyme-inhibiting aptamer bearing a target-molecule binding site and was able to detect target DNAs by measuring the thrombin activity in ahomogeneous solution.
(via Semantic Scholar)
europepmc.org (repository)
Source: ORCID
Added: October 9, 2020
2008 journal article
Aggregation and fibrillation study of a-synuclein under applied voltage
Electrochemistry, 76(8), 614–618.
Contributors: Y. Osawa*, K. Ikebukuro *, N. Kobayashi *, S. Han *, C. Nakamura * & K. Sode*
author keywords: aggregation; application of voltage; alpha-synuclein; natively unfolded protein
TL;DR:
Voltage is applied to amyloidogenic protein, α-synuclein, which is related to Parkinson’s disease to control the aggregation of α- Syn, which has a negative charge, by applying voltage to it, demonstrating that this technique might be useful not only to efficiently control aggregation ofα-syn but also to understand the mechanism of aggregation and fibrillation of α.
(via Semantic Scholar)
Source: ORCID
Added: October 9, 2020
2008 journal article
DNA-Templated Polymerization of Side-Chain-Functionalized Peptide Nucleic Acid Aldehydes
Journal of the American Chemical Society, 130(14), 4646–4659.
MeSH headings : Aldehydes / chemical synthesis; Aldehydes / chemistry; DNA / chemical synthesis; DNA / chemistry; Kinetics; Magnetic Resonance Spectroscopy; Molecular Conformation; Nucleic Acid Conformation; Peptide Nucleic Acids / chemistry; Polymers / chemical synthesis; Spectrometry, Mass, Electrospray Ionization
TL;DR:
The findings represent a significant step toward the evolution of sequence-defined synthetic polymers and also demonstrate that enzyme-free nucleic acid-templated polymerization can occur efficiently using substrates with a wide range of side-chain structures, functionalization positions within each building block, and functionalization densities.
(via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020
2008 journal article
Estimation of the effective static moment arms of the tendons in the index finger extensor mechanism
Journal of Biomechanics, 41(7), 1567–1573.
author keywords: finger; moment arm; extensor hood; finger posture
MeSH headings : Arm / anatomy & histology; Arm / physiology; Fingers / anatomy & histology; Fingers / physiology; Humans; Models, Biological; Movement / physiology; Muscle, Skeletal / physiology; Tendons / physiology
TL;DR:
Effective static moment arms (ESMAs), which represent the net effects of the tendon force on joint moments in static finger postures, were estimated for the 4 degrees of freedom in the index finger by directly correlating the applied tendon force to the measured resultant joint Moments in cadaveric hand specimens.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Effect of a Gravity-Compensating Orthosis on Reaching After Stroke: Evaluation of the Therapy Assistant WREX
Archives of Physical Medicine and Rehabilitation, 89(11), 2121–2128.
author keywords: Orthotic devices; Rehabilitation; Stroke; Upper extremity
MeSH headings : Adult; Aged; Aged, 80 and over; Biomechanical Phenomena; Electromyography; Equipment Design; Female; Gravitation; Humans; Male; Middle Aged; Orthotic Devices; Paresis / rehabilitation; Stroke Rehabilitation; Therapy, Computer-Assisted / instrumentation; Upper Extremity
TL;DR:
By reducing requirements for shoulder activation, the Therapy Assistant WREX improved reaching performance among stroke survivors compared with free reaching, thereby potentially facilitating practice of functional tasks.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Exercise enhances vaccine-induced antigen-specific T cell responses
Vaccine, 26(42), 5407–5415.
author keywords: adaptive immunity; cytokines; cell proliferation
MeSH headings : Animals; Body Composition; CD4-Positive T-Lymphocytes / immunology; CD4-Positive T-Lymphocytes / metabolism; Cell Proliferation; Cytokines / biosynthesis; Cytokines / immunology; Female; Lymphocyte Activation / immunology; Mice; Mice, Inbred C57BL; Motor Activity; Ovalbumin / immunology; Substrate Specificity; Vaccination
TL;DR:
Coupling moderate exercise with vaccination may enhance vaccine efficacy for the prevention and/or therapy of numerous diseases.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Collagen fiber alignment and biaxial mechanical behavior of porcine urinary bladder derived extracellular matrix
Biomaterials, 29(36), 4775–4782.
author keywords: Extracellular matrix; Scaffold; Collagen fiber alignment; Biaxial mechanical behavior
MeSH headings : Animals; Biomechanical Phenomena; Elastic Modulus; Extracellular Matrix / metabolism; Fibrillar Collagens / metabolism; Mucous Membrane / metabolism; Sus scrofa / metabolism; Urinary Bladder / metabolism
TL;DR:
Evaluating the collagen fiber alignment and biaxial mechanical behavior of ECM scaffold material harvested from porcine urinary bladder tunica mucosa and basement membrane found UBML and UBS showed quite different mechanical behavior for the applied loading patterns with UBS showing a much more pronounced toe region.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix
Biomaterials, 29(11), 1630–1637.
author keywords: extracellular matrix; viscoelasticity; rheology; scaffold; gel
MeSH headings : Animals; Cell Adhesion; Cell Proliferation; Cells, Cultured; Extracellular Matrix / metabolism; Extracellular Matrix / ultrastructure; Gels / chemistry; Gels / metabolism; Kinetics; Microscopy, Electron, Scanning; Myocytes, Smooth Muscle / cytology; Rats; Rheology; Swine; Tissue Scaffolds / chemistry; Urinary Bladder / metabolism; Viscosity
TL;DR:
An intact form of UBM can be successfully solubilized without purification steps and induced to repolymerize into a gel form of the UBM biologic scaffold material, which supported the adhesion and growth of rat aortic smooth muscle cells when cultured under static in vitro conditions.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Uniaxial and biaxial properties of terminally sterilized porcine urinary bladder matrix scaffolds
Journal of Biomedical Materials Research Part B: Applied Biomaterials, 84B(2), 408–414.
author keywords: sterilization; extracellular matrix; material properties; strength; scaffolds
MeSH headings : Animals; Biocompatible Materials; Extracellular Matrix; Materials Testing; Sterilization; Swine; Tensile Strength; Tissue Scaffolds; Urinary Bladder
TL;DR:
The present study showed that the choice of terminal sterilization method affects the structural properties of scaffolds composed of extracellular matrix.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
Hydrated versus lyophilized forms of porcine extracellular matrix derived from the urinary bladder
Journal of Biomedical Materials Research Part A, 87A(4), 862–872.
author keywords: extracellular matrix; lyophilization; freeze-drying; scaffold; structural properties; urinary bladder
MeSH headings : Animals; Biocompatible Materials / chemistry; Extracellular Matrix / chemistry; Freeze Drying; Humans; Hydrostatic Pressure; Materials Testing; Mice; NIH 3T3 Cells; Permeability; Stress, Mechanical; Swine; Tissue Engineering / methods; Tissue Scaffolds / chemistry; Urinary Bladder / anatomy & histology; Urinary Bladder / chemistry; Water / chemistry
TL;DR:
It is concluded that lyophilization affects the overall in vitro cell growth of NIH 3T3 cells and the ultrastructural morphology of UBM devices, but does not result in significant changes in structural properties.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2008 journal article
A combinatorial approach to microfluidic mixing
Journal of Micromechanics and Microengineering, 18(11), 115019.
TL;DR:
A new computational approach to the modeling and design of efficient microfluidic mixers is demonstrated, and the mixers created provide far more rapid mixing than previous designs.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
A Parametric Study of Sample Lysis and DNA Purification Techniques for Use in Automated Devices
Analytical Letters, 41(10), 1701–1719.
author keywords: automatable; DNA purification; lysis; sample preparation; solid phase extraction
TL;DR:
An optimized protocol has been developed for use with both spiked buffers and nasal wash, and all steps of this protocol are suitable for incorporation into a field-portable, automated sample preparation device.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Two simple and rugged designs for creating microfluidic sheath flow
Lab on a Chip, 8(7), 1097.
MeSH headings : Computer Simulation; Equipment Design; Microfluidic Analytical Techniques / instrumentation
TL;DR:
A simple design capable of 2-dimensional hydrodynamic focusing is proposed and successfully demonstrated, which eliminates the need to carefully balance the flow of two or more sheath inlets and easily manufactured using current microfabrication techniques.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Home diagnostics to music
Nature, 456(7219), 178–179.
MeSH headings : Biosensing Techniques / economics; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Biosensing Techniques / trends; Compact Disks; Diagnostic Equipment / economics; Diagnostic Equipment / trends; Humans; Microfluidic Analytical Techniques / methods
TL;DR:
With the latest technology, you could one day perform bioassays on your home compact-disc player, just like in the doctor's surgery.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Immobilized Proanthocyanidins for the Capture of Bacterial Lipopolysaccharides
Analytical Chemistry, 80(6), 2113–2117.
MeSH headings : Bacteria / chemistry; Fluorescence; Lipopolysaccharides / chemistry; Proanthocyanidins / analysis
TL;DR:
Molar comparison of polymyxin B to proanthocyanidins indicated that the Sepharose immobilized PACs have a binding affinity for LPS similar to that of polymethine B, which is known to bind the lipid A component of LPS.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
Impact of cranberry on Escherichia coli cellular surface characteristics
Biochemical and Biophysical Research Communications, 377(3), 992–994.
author keywords: Vaccinium macrocarpon; Cranberry; Proanthocyandin; Anti-adhesive; Antibacterial
MeSH headings : Bacterial Adhesion / drug effects; Bacterial Adhesion / physiology; Cell Membrane / drug effects; Cell Membrane / physiology; Cell Membrane / ultrastructure; Escherichia coli / drug effects; Escherichia coli / physiology; Escherichia coli / ultrastructure; Microscopy, Electron, Scanning; Plant Extracts / chemistry; Plant Extracts / pharmacology; Receptors, Immunologic / drug effects; Receptors, Immunologic / physiology; Receptors, Immunologic / ultrastructure; Vaccinium macrocarpon / chemistry
TL;DR:
It is shown that the morphology of E. coli is changed when grown in the presence of juice or extract from Vaccinium macrocarpon (cranberry), andGene expression analysis indicates the down regulation of flagellar basal body rod and motor proteins.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
The good, the bad, and the tiny: a review of microflow cytometry
Analytical and Bioanalytical Chemistry, 391(5), 1485–1498.
author keywords: flow cytometry; microfluidics; fluid focusing; integrated optics; cell sorter
MeSH headings : Biomechanical Phenomena; Biotechnology / instrumentation; Biotechnology / methods; Cell Separation / instrumentation; Cell Separation / methods; Electrophoresis, Microchip / instrumentation; Electrophoresis, Microchip / methods; Equipment Design; Flow Cytometry / instrumentation; Flow Cytometry / methods; Microfluidics / instrumentation; Microfluidics / methods; Microfluidics / trends; Online Systems / instrumentation; Reproducibility of Results; Sensitivity and Specificity
TL;DR:
Each of these four areas is discussed in detail in terms of the progress of development, the continuing limitations, and potential future directions for microflow cytometers.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2008 journal article
An Analysis of EMG Electrode Configuration for Targeted Muscle Reinnervation Based Neural Machine Interface
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 16(1), 37–45.
Contributors: H. Huang* , P. Zhou *, G. Li * & T. Kuiken *
author keywords: classification; clinical EMG electrode configurations; control of artificial limbs; electromyography (EMG); prosthesis; targeted muscle reinnervation
MeSH headings : Adult; Algorithms; Artificial Limbs; Electrodes, Implanted; Electromyography / instrumentation; Electrophysiology; Female; Hand / innervation; Hand / physiology; Humans; Linear Models; Male; Movement / physiology; Muscle, Skeletal / innervation; Pattern Recognition, Automated; Shoulder / physiology; Shoulder / surgery
TL;DR:
A practical protocol for clinical electrode placement was developed, which does not rely on complex HD EMG experiment and analysis while maintaining a classification accuracy of 88.7plusmn4.5%, and provides important guidelines for practical electrode placement that can promote future clinical application of TMR and EMG PR in the control of multifunctional prostheses.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
2008 journal article
Control of a Six Degree of Freedom Prosthetic Arm After Targeted Muscle Reinnervation Surgery
Archives of Physical Medicine and Rehabilitation, 89(11), 2057–2065.
Contributors: L. Miller, R. Lipschutz, K. Stubblefield, B. Lock, H. Huang* , T. Williams III, R. Weir, T. Kuiken
author keywords: Artificial limbs; Electromyography; Nerve transfer; Rehabilitation
MeSH headings : Artificial Limbs; Electrodes, Implanted; Electromyography; Humans; Male; Man-Machine Systems; Middle Aged; Nerve Transfer; Pectoralis Muscles / innervation; Prosthesis Design; Range of Motion, Articular; Shoulder / innervation; Upper Extremity / innervation
TL;DR:
This proof-of-concept study shows that advances in control of shoulder disarticulation-level prostheses can improve the quality of movement and may spur the development of more advanced and complex componentry for these amputees.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020
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