Works Published in 2009

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Displaying works 41 - 60 of 96 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2009 journal article

Cumulative effect of amino acid substitution for the development of fructosyl valine-specific fructosyl amine oxidase

Enzyme and Microbial Technology, 44(1), 52–56.

By: S. Kim*, S. Miura*, S. Ferri*, W. Tsugawa* & K. Sode*

Contributors: S. Kim*, S. Miura*, S. Ferri*, W. Tsugawa* & K. Sode*

author keywords: Biosensor; Diabetes; Fructosyl amine oxidase; Hemoglobin A(1c) (HbA(1c)); Substrate specificity
TL;DR: The results support the proposed 3D model, and the resulting f-αVal-specific mutants are expected to be applied to the enzymatic measurement of HbA1c. (via Semantic Scholar)
Source: ORCID
Added: October 9, 2020

2009 journal article

BioCapacitor-A novel category of biosensor

Biosensors & Bioelectronics, 24(7), 1837–1842.

By: T. Hanashi*, T. Yamazaki*, W. Tsugawa*, S. Ferri*, D. Nakayama*, M. Tomiyama*, K. Ikebukuro*, K. Sode*

Contributors: T. Hanashi*, T. Yamazaki*, W. Tsugawa*, S. Ferri*, D. Nakayama*, M. Tomiyama*, K. Ikebukuro*, K. Sode*

author keywords: Biofuel cells; Glucose dehydrogenase; Continuous glucose monitoring; Glucose sensor; Capacitor; Wireless sensing system
MeSH headings : Biosensing Techniques / instrumentation; Electric Capacitance; Electrochemistry / instrumentation; Electrodes; Enzymes, Immobilized / chemistry; Equipment Design; Equipment Failure Analysis; Glucose / analysis; Glucose / chemistry; Glucose 1-Dehydrogenase / chemistry; Reproducibility of Results; Sensitivity and Specificity
TL;DR: A BioCapacitor employing FAD-dependent glucose dehydrogenase (FADGDH) as its anodic catalyst can be operated as a self-powered enzyme sensor. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: ORCID
Added: October 9, 2020

2009 journal article

An Aptamer-Based Bound/Free Separation System for Protein Detection

Electroanalysis, 21(11), 1297–1302.

By: M. Fukasawa*, W. Yoshida*, H. Yamazaki, K. Sode* & K. Ikebukuro*

Contributors: M. Fukasawa*, W. Yoshida*, H. Yamazaki, K. Sode* & K. Ikebukuro*

author keywords: Simple bound/free separation; Aptamers; Complementary strand-immobilized (CSI) beads; Structural change of aptamer; PQQGDH
TL;DR: Aptamer hybridizes with its complementary strand and can be recovered easily and detected by PQQGDH activity, which allows the detection of 270 pM thrombin and 1 nM IgE. (via Semantic Scholar)
Source: ORCID
Added: October 9, 2020

2009 journal article

Contactless dielectrophoresis: a new technique for cell manipulation

Biomedical Microdevices, 11(5), 997–1006.

By: H. Shafiee*, J. Caldwell*, M. Sano* & R. Davalos*

author keywords: BioMEMS; Biochip; Dielectrophoretic; Microfluidics; Sample handling; Electrorotation; Sample preparation
MeSH headings : Cell Line, Tumor; Cell Separation / instrumentation; Dimethylpolysiloxanes / chemistry; Electric Impedance; Electrodes; Electrophoresis / instrumentation; Humans; Microfluidic Analytical Techniques / instrumentation; Models, Theoretical; Rotation
TL;DR: This technique combines the cell manipulation abilities of traditional DEP with the ease of fabrication found in insulator-based technologies and was able to demonstrate cell responses unique to the DEP effect in three separate cell lines. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

Recent Progress Toward the Templated Synthesis and Directed Evolution of Sequence-Defined Synthetic Polymers

Chemistry & Biology, 16(3), 265–276.

By: Y. Brudno* & D. Liu*

MeSH headings : Base Sequence; Directed Molecular Evolution / methods; Directed Molecular Evolution / trends; Nucleic Acids / chemical synthesis; Nucleic Acids / chemistry; Nucleotides / chemical synthesis; Nucleotides / chemistry; Phosphates / chemical synthesis; Phosphates / chemistry; Polymers / chemical synthesis; Polymers / chemistry; Ribose / chemical synthesis; Ribose / chemistry; Ribosomes / metabolism
TL;DR: This review covers recent advances in the enzymatic and nonenzymatic templated polymerization of nonnatural polymers and their potential applications in the directed evolution of sequence-defined synthetic polymers. (via Semantic Scholar)
Sources: Crossref, ORCID, NC State University Libraries
Added: August 28, 2020

2009 journal article

Extracellular matrix as a biological scaffold material: Structure and function

Acta Biomaterialia, 5(1), 1–13.

By: S. Badylak*, D. Freytes* & T. Gilbert*

author keywords: Extracellular matrix; Scaffold; Remodeling; Degradation; Ultrastructure
MeSH headings : Animals; Biochemistry / methods; Biocompatible Materials / chemistry; Biomedical Engineering; Collagen / chemistry; Extracellular Matrix / chemistry; Extracellular Matrix / physiology; Freeze Drying; Humans; Materials Testing; Microscopy, Electron, Scanning; Models, Biological; Stress, Mechanical; Tissue Engineering / methods; Tissue Scaffolds
TL;DR: An overview of the composition and structure of selected ECM scaffolding materials, the effects of manufacturing methods upon the structural properties and resulting mechanical behavior of the scaffold materials, and the in vivo degradation and remodeling of ECm scaffolds with an emphasis on tissue function is provided. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

Geometry and force control of cell function

Journal of Cellular Biochemistry, 108(5), 1047–1058.

author keywords: STEM CELLS; BIOPHYSICAL REGULATION; SCAFFOLDS; BIOREACTORS; TISSUE ENGINEERING
MeSH headings : Animals; Biomedical Research; Biomimetics / methods; Cell Culture Techniques; Humans; Models, Biological; Rats; Regeneration; Stem Cells / cytology; Stem Cells / physiology; Stress, Physiological; Tissue Engineering / methods; Tissue Scaffolds; Transplants
TL;DR: Tissue engineering is becoming increasingly ambitious in its efforts to create functional human tissues, and to provide stem cell scientists with culture systems of high biological fidelity, with emphasis on the derivation of design principles from the development and the geometry‐force control of cell function. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

Oxygen diffusivity of biologic and synthetic scaffold materials for tissue engineering

Journal of Biomedical Materials Research Part A, 91A(4), 1010–1017.

By: J. Valentin*, D. Freytes*, J. Grasman*, C. Pesyna*, J. Freund*, T. Gilbert*, S. Badylak*

author keywords: biologic scaffold material; extracellular matrix; tissue engineering; oxygen diffusivity; ultrastructure
MeSH headings : Animals; Biocompatible Materials / pharmacology; Diffusion / drug effects; Extracellular Matrix / drug effects; Extracellular Matrix / ultrastructure; Materials Testing; Oxygen / metabolism; Sus scrofa; Temperature; Time Factors; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR: Each material composed of ECM has unique oxygen diffusivity values, and these values may be dependent on the scaffold's ultrastructure, the current study showed. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

A simple sheath-flow microfluidic device for micro/nanomanufacturing: fabrication of hydrodynamically shaped polymer fibers

Lab on a Chip, 9(21), 3126.

By: A. Thangawng*, P. Howell Jr, J. Richards*, J. Erickson* & F. Ligler*

MeSH headings : Equipment Design; Microfluidic Analytical Techniques / methods; Microscopy, Electron, Scanning; Nanofibers / chemistry; Polymethyl Methacrylate / chemistry; Surface Properties
TL;DR: A simple sheath flow microfluidic device is used to fabricate polymer micro/nanofibers that have precisely controlled shapes and sizes. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

Multi-wavelength microflow cytometer using groove-generated sheath flow

Lab on a Chip, 9(13), 1942.

By: J. Golden*, J. Kim*, J. Erickson*, L. Hilliard*, P. Howell*, G. Anderson*, M. Nasir*, F. Ligler*

MeSH headings : Animals; Colony Count, Microbial; Equipment Design; Escherichia coli / immunology; Escherichia coli / isolation & purification; Flow Cytometry / instrumentation; Flow Cytometry / methods; Fluorescent Dyes; Immunoglobulin G / immunology; Microfluidic Analytical Techniques / instrumentation; Microfluidic Analytical Techniques / methods; Microspheres; Phycoerythrin / analysis; Phycoerythrin / immunology; Sensitivity and Specificity
TL;DR: A microflow cytometer was developed that ensheathed the sample (core) fluid on all sides and interrogated each particle in the sample stream at four different wavelengths, capable of discriminating microspheres with different amounts of the fluorophores used for coding and detecting the presence of a phycoerythrin antibody complex on the surface of the microsphere. (via Semantic Scholar)
UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: Crossref
Added: August 28, 2020

2009 journal article

Multiplexed Detection of Bacteria and Toxins Using a Microflow Cytometer

Analytical Chemistry, 81(13), 5426–5432.

By: J. Kim*, G. Anderson*, J. Erickson*, J. Golden*, M. Nasir* & F. Ligler*

MeSH headings : Antibodies, Immobilized / chemistry; Antibodies, Immobilized / immunology; Bacteria / chemistry; Bacteria / isolation & purification; Enterotoxins / analysis; Escherichia coli / chemistry; Flow Cytometry / instrumentation; Flow Cytometry / methods; Fluorescent Dyes / chemistry; Listeria / chemistry; Microfluidics / instrumentation; Microfluidics / methods; Ricin / analysis; Salmonella / chemistry; Signal Processing, Computer-Assisted; Toxins, Biological / analysis
TL;DR: A microfabricated flow cytometer was used to demonstrate multiplexed detection of bacteria and toxins using fluorescent coded microspheres using antibodies bound by the presence of phycoerythrin tracer in a sandwich immunoassay format. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

Organic Photodiodes for Biosensor Miniaturization

Analytical Chemistry, 81(9), 3455–3461.

By: J. Wojciechowski, L. Shriver-Lake, M. Yamaguchi, E. Füreder, R. Pieler, M. Schamesberger, C. Winder, H. Prall, M. Sonnleitner, F. Ligler*

MeSH headings : Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Dose-Response Relationship, Drug; Electrodes; Electronics; Enterotoxins / isolation & purification; Glass / chemistry; Luminescence; Miniaturization; Organic Chemicals / chemistry; Sensitivity and Specificity
TL;DR: The integration of polymer diodes onto a biosensor chip is described to create a disposable device that includes both the detector and the sensing surface coated with immobilized capture antibody. (via Semantic Scholar)
Source: Crossref
Added: August 28, 2020

2009 journal article

A faster ordered-subset convex algorithm for iterative reconstruction in a rotation-free micro-CT system

Physics in Medicine and Biology, 54(4), 1061–1072.

By: E. Quan n & D. Lalush n

MeSH headings : Algorithms; Artificial Intelligence; Imaging, Three-Dimensional / methods; Pattern Recognition, Automated / methods; Phantoms, Imaging; Radiographic Image Enhancement / methods; Radiographic Image Interpretation, Computer-Assisted / methods; Reproducibility of Results; Sensitivity and Specificity; Tomography, X-Ray Computed / methods
TL;DR: The modified OSC (MOSC) algorithm was applied to a rotation-free micro-CT system that was proposed previously, observed its performance, and compared with the OSC algorithm for 3D cone-beam reconstruction and concluded that the MOSC algorithm is more efficient than OSC and provides comparable images. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Crossref
Added: August 28, 2020

2009 journal article

Interactions between endothelial cells and electrospun methacrylic terpolymer fibers for engineered vascular replacements

Journal of Biomedical Materials Research Part A, 91A(4), 1131–1139.

By: A. Veleva n, D. Heath*, J. Johnson*, J. Nam*, C. Patterson*, J. Lannutti*, S. Cooper*

author keywords: methacrylic terpolymers; biocompatibility; electrospinning; endothelial cells; engineered vascular grafts
MeSH headings : Blood Vessel Prosthesis; Cell Adhesion / drug effects; Cell Communication / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Endothelial Cells / cytology; Endothelial Cells / drug effects; Endothelial Cells / metabolism; Humans; Methacrylates / pharmacology; Microscopy, Electron, Scanning; Polymers / pharmacology; Porosity / drug effects; Tissue Engineering / methods; von Willebrand Factor / metabolism
TL;DR: It was found that the terpolymer is cytocompatible allowing endothelial cell growth, with random fibers being more effective in promoting enhanced cellular activities than oriented fibers. (via Semantic Scholar)
Source: Crossref
Added: February 24, 2020

2009 conference paper

Promise of embedded system with GPU in artificial leg control: Enabling time-frequency feature extraction from electromyography

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 6926–6929.

By: W. Xiao, H. Huang*, Y. Sun & Q. Yang

Contributors: W. Xiao, H. Huang*, Y. Sun & Q. Yang

Event: 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

author keywords: Electromyography; control of artificial limbs; embedded system; high performance computing
MeSH headings : Algorithms; Artificial Limbs / statistics & numerical data; Biomedical Engineering; Electromyography / statistics & numerical data; Humans; Male; Pattern Recognition, Automated; Signal Processing, Computer-Assisted
TL;DR: High performance GPU shows a great promise for EMG-controlled artificial legs and other medical applications that need high-speed and real-time computation. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020

2009 conference paper

Toward the development of a neural interface for lower limb prosthesis control

2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, 2111–2114.

By: L. Hargrove*, H. Huang*, A. Schultz*, B. Lock*, R. Lipschutz* & T. Kuiken*

Contributors: L. Hargrove*, H. Huang*, A. Schultz*, B. Lock*, R. Lipschutz* & T. Kuiken*

Event: 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society

MeSH headings : Amputation, Surgical / rehabilitation; Artificial Limbs; Electromyography; Femur / surgery; Gait / physiology; Humans; Knee Joint / physiology; Knee Joint / physiopathology; Leg / surgery; Motor Activity; Movement; Prosthesis Implantation / methods; Reference Values; Walking
TL;DR: The work completed to date in developing a novel lower limb neural interface is described, which addresses the needs of patients with high-level amputations who need to perform multi-joint coordinated movements. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020

2009 journal article

A Strategy for Identifying Locomotion Modes Using Surface Electromyography

IEEE Transactions on Biomedical Engineering, 56(1), 65–73.

By: H. Huang*, T. Kuiken* & R. Lipschutz*

Contributors: H. Huang*, T. Kuiken* & R. Lipschutz*

author keywords: Electromyography (EMG); neural-machine interface; pattern recognition (PR); prosthesis; targeted muscle reinnervation
MeSH headings : Adult; Amputation, Surgical; Analysis of Variance; Artificial Limbs; Discriminant Analysis; Electromyography; Female; Humans; Leg; Male; Man-Machine Systems; Middle Aged; Muscle, Skeletal / physiology; Neural Networks, Computer; Pattern Recognition, Automated; Walking / physiology
TL;DR: This study investigated the use of surface electromyography (EMG) combined with pattern recognition (PR) to identify user locomotion modes and showed reliable classification for the seven tested modes. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020

2009 journal article

Spatial Filtering Improves EMG Classification Accuracy Following Targeted Muscle Reinnervation

Annals of Biomedical Engineering, 37(9), 1849–1857.

author keywords: Electromyography; Targeted muscle reinnervation; Spatial filter; Neural-machine interface
MeSH headings : Adult; Artificial Limbs; Disarticulation / rehabilitation; Electromyography; Female; Humans; Humerus; Male; Middle Aged; Motor Activity; Muscle Contraction; Muscle, Skeletal / innervation; Muscle, Skeletal / physiopathology; Muscle, Skeletal / surgery
TL;DR: Double differential EMG recordings with high spatial resolution over reinnervated muscles could capture focal muscle activity and improve the classification accuracy of identifying intended movements in TMR patients with transhumeral or shoulder disarticulation amputations. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries, ORCID
Added: January 19, 2020

2009 journal article

Pulsed laser deposition of antimicrobial silver coating on Ormocer (R) microneedles

BIOFABRICATION, 1(4).

By: S. Gittard n, R. Narayan n, C. Jin n, A. Ovsianikov*, B. Chichkov*, N. Monteiro-Riviere n, S. Stafslien*, B. Chisholm*

MeSH headings : Anti-Bacterial Agents / administration & dosage; Anti-Bacterial Agents / chemistry; Biotechnology; Cell Survival / drug effects; Ceramics / chemistry; Diffusion; Drug Delivery Systems / instrumentation; Humans; Keratinocytes; Microbial Sensitivity Tests; Microscopy, Electron, Scanning; Microtechnology / methods; Needles; Organically Modified Ceramics; Silanes / administration & dosage; Silanes / chemistry; Silver / administration & dosage; Silver / chemistry; Staphylococcus aureus / drug effects
TL;DR: It is indicated that coating microneedles with silver thin films using pulsed laser deposition is a useful and novel approach for creating microneEDles with antimicrobial functionality. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2009 journal article

CHANGES IN LIPID-ENCAPSULATED MICROBUBBLE POPULATION DURING CONTINUOUS INFUSION AND METHODS TO MAINTAIN CONSISTENCY

ULTRASOUND IN MEDICINE AND BIOLOGY, 35(10), 1748–1755.

By: M. Kaya n, T. Gregory n & P. Dayton n

author keywords: Microbubbles; Contrast agent; Ultrasound; Size distribution; Concentration; Mixing; Floatation; Rotating syringe
MeSH headings : Contrast Media / administration & dosage; Drug Administration Schedule; Humans; Infusions, Intravenous; Lipids / administration & dosage; Microbubbles; Models, Theoretical; Particle Size; Rheology; Syringes; Ultrasonography / methods; Viscosity
TL;DR: The results are significant for researchers using microbubble contrast agents in continuous-infusion applications where it is important to maintain consistent contrast agent delivery rate, or in situations where the injection syringe cannot be mixed immediately before administration. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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