Works Published in 2012

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Displaying works 61 - 80 of 101 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2012 conference paper

Set membership state and parameter estimation for nonlinear differential equations with sparse discrete measurements

Ieee international conference on systems man and cybernetics conference, 72–77.

By: S. Marvel n & C. Williams n

TL;DR: This paper presents a method to perform parameter and state estimation in a bounded-error context for nonlinear continuous-time systems with sparse, discrete measurements and demonstrates how preprocessing the measurements through the addition of application specific stabilizing bounds vastly improves bounded parameters and state estimations. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

The influence of a unilateral fixed ankle on metabolic and mechanical demands during walking in unimpaired young adults

JOURNAL OF BIOMECHANICS, 45(14), 2405–2410.

By: C. Wutzke*, G. Sawicki n & M. Lewek*

author keywords: Gait; Biomechanics; Metabolic cost; Ankle
MeSH headings : Adult; Ankle; Energy Metabolism; Female; Hip; Humans; Male; Muscle Strength; Orthopedic Fixation Devices; Walking
TL;DR: It is suggested that walking with reduced ankle power increases metabolic demand due to the redistribution of mechanical power generation from highly efficient ankle muscle-tendons to less efficient hip muscle-Tendons. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Set membership experimental design for biological systems

BMC SYSTEMS BIOLOGY, 6.

By: S. Marvel n & C. Williams n

MeSH headings : Models, Biological; Research Design; Uncertainty
TL;DR: A bounded-error experimental design framework for nonlinear continuous-time systems when few data measurements are available that is able to identify candidate measurement time points that maximize information corresponding to biologically relevant metrics and determine the number at which additional measurements begin to provide insignificant information. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Release Profiles of Tricalcium Phosphate Nanoparticles from Poly(L-lactic acid) Electrospun Scaffolds with Single Component, Core-Sheath, or Porous Fiber Morphologies: Effects on hASC Viability and Osteogenic Differentiation

MACROMOLECULAR BIOSCIENCE, 12(7), 893–900.

By: M. Asli n, B. Pourdeyhimi n & E. Loboa n

author keywords: biomaterials; controlled release scaffolds; human adipose derived stem cells; nanoparticles; osteogenesis
MeSH headings : Adipose Tissue / cytology; Adipose Tissue / drug effects; Adult; Biocompatible Materials / chemical synthesis; Biocompatible Materials / pharmacology; Bone and Bones / cytology; Bone and Bones / physiology; Calcium Phosphates / chemistry; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Cell Survival / drug effects; Cells, Cultured; Female; Humans; Kinetics; Lactic Acid / chemistry; Microscopy, Electron, Scanning; Nanoparticles / chemistry; Nanoparticles / ultrastructure; Polyesters; Polymers / chemistry; Porosity; Stem Cells / cytology; Stem Cells / drug effects; Surface Properties; Tissue Engineering; Tissue Scaffolds
TL;DR: Results indicate that single component and porous fiber scaffolds exhibit an initial-burst release profile whereas core-sheath fibers show a steady release, and osteogenic differentiation of hASC and cell-mediated calcium accretion are largest on porous fibers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Mapping Microvasculature with Acoustic Angiography Yields Quantifiable Differences between Healthy and Tumor-bearing Tissue Volumes in a Rodent Model

RADIOLOGY, 264(3), 733–740.

MeSH headings : Animals; Contrast Media; Disease Models, Animal; Female; Fibrosarcoma / diagnostic imaging; Image Processing, Computer-Assisted; Imaging, Three-Dimensional / methods; Microbubbles; Microcirculation; Neovascularization, Pathologic / diagnostic imaging; Prospective Studies; Rats; Rats, Inbred F344; Transducers; Ultrasonography
TL;DR: Vascular network quantification by using high-spatial-resolution acoustic angiographic images is feasible and suggests that the angiogenic processes associated with tumor development in the models studied result in higher instances of vessel tortuosity near the tumor site. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Antibacterial activity of zinc oxide-coated nanoporous alumina

MATERIALS SCIENCE AND ENGINEERING B-ADVANCED FUNCTIONAL SOLID-STATE MATERIALS, 177(12), 992–998.

By: S. Skoog n, M. Bayati n, P. Petrochenko n, S. Stafslien*, J. Daniels*, N. Cilz*, D. Comstock*, J. Elam*, R. Narayan n

author keywords: Aluminum oxide; Zinc oxide; Atomic layer deposition; Nanoporous material; Antibacterial material
TL;DR: It is suggested that zinc oxide-coated nanoporous alumina membranes have activity against some Gram-positive and Gram-negative bacteria that are associated with skin colonization and skin infection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 article

Trapping cells on a stretchable microwell array for single-cell analysis (vol 402, pg 1065, 2012)

Analytical and Bioanalytical Chemistry, Vol. 404, pp. 2519–2519.

By: Y. Wang, P. Shah, C. Phillips, C. Sims & N. Allbritton

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

The effects of orthotic heel lifts on achilles tendon force and strain during running

Journal of Applied Biomechanics, 28(5), 511–519.

By: D. Farris, E. Buckeridge, G. Trewartha & M. McGuigan

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Separation of fluorescently labeled phosphoinositides and sphingolipids by capillary electrophoresis

JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 907, 79–86.

By: K. Wang*, D. Jiang*, C. Sims* & N. Allbritton n

author keywords: Capillary electrophoresis; Sphingolipid; Phosphoinositide lipid; Phospholipid separation
MeSH headings : 1-Propanol / chemistry; Boron Compounds / chemistry; Cell Line, Tumor; Electrophoresis, Capillary / methods; Fluorescein / chemistry; Fluorescent Dyes / chemistry; Humans; Hydrogen-Ion Concentration; Limit of Detection; Phosphates / chemistry; Phosphatidylinositols / chemistry; Phosphatidylinositols / isolation & purification; Reproducibility of Results; Sphingolipids / chemistry; Sphingolipids / isolation & purification
TL;DR: A simple and robust separation method for SFL and S1PFL and various metabolites of phosphoinositide-related signal transduction is expected to enable improved enzymatic assays for biological and clinical applications. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Linking the mechanics and energetics of hopping with elastic ankle exoskeletons

Journal of Applied Physiology, 113(12), 1862–1872.

By: D. Farris & G. Sawicki

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Development of a surrogate biomodel for the investigation of clubfoot bracing

Journal of Pediatric Orthopaedics, 32(7), E47–52.

By: A. DiMeo, D. Lalush, E. Grant & J. Morcuende

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Development of a Peptidase-Resistant Substrate for Single-Cell Measurement of Protein Kinase B Activation

ANALYTICAL CHEMISTRY, 84(16), 7195–7202.

By: A. Proctor*, Q. Wang*, D. Lawrence* & N. Allbritton n

MeSH headings : Amino Acid Sequence; Amino Acid Substitution; Arginine; Cytosol / metabolism; Drug Design; Enzyme Activation / drug effects; HeLa Cells; Humans; Oligopeptides / chemistry; Oligopeptides / metabolism; Oligopeptides / pharmacology; Peptide Hydrolases / metabolism; Phosphorylation; Protein Binding; Protein Kinase Inhibitors / chemistry; Protein Kinase Inhibitors / metabolism; Protein Kinase Inhibitors / pharmacology; Proteolysis; Proto-Oncogene Proteins c-akt / antagonists & inhibitors; Proto-Oncogene Proteins c-akt / metabolism; Single-Cell Analysis
TL;DR: An iterative design strategy using three criteria was utilized to develop a peptidase-resistant substrate peptide for protein kinase B, finding widespread utility in both lysate-based and single-cell assays of kinase activity. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

13C magnetic resonance spectroscopy detection of changes in serine isotopomers reflects changes in mitochondrial redox status

MAGNETIC RESONANCE IN MEDICINE, 68(3), 671–679.

By: C. Johnson*, A. Tikunov*, H. Lee*, J. Wolak*, P. Pediaditakis*, D. Romney*, E. Holmuhamedov*, M. Gamcsik n, J. Macdonald*

author keywords: serine 13C isotopomers; 13C NMR spectroscopy; mitochondrial redox; 2-13C-glycine; hepatocytes; confocal microscopy
MeSH headings : Animals; Carbon Isotopes; Cells, Cultured; Hepatocytes / metabolism; Hepatocytes / ultrastructure; Male; Mitochondria, Liver / metabolism; NAD / analysis; Oxidation-Reduction; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Serine / analysis
TL;DR: It is demonstrated that 13C magnetic resonance spectroscopy monitoring of the formation of serine isotopomers in isolated rat hepatocytes given 2‐13C‐glycine reflects the changes of mitochondrial redox status. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Elastic recoil can either amplify or attenuate muscle-tendon power, depending on inertial vs. fluid dynamic loading

JOURNAL OF THEORETICAL BIOLOGY, 313, 68–78.

author keywords: Muscle power amplification; Gearing; Mechanical advantage; Mathematical model; Inertial and viscous loads
MeSH headings : Animals; Biomechanical Phenomena / physiology; Computer Simulation; Elasticity; Hydrodynamics; Models, Biological; Muscle Contraction / physiology; Muscle, Skeletal / physiology; Tendons / physiology; Xenopus laevis
TL;DR: The model predicts that for fluid loads, the benefit from a compliant tendon is modest, and when the system is 'poorly tuned' (i.e., inappropriate EMA), MT power attenuation can be severe. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

High payload dual therapeutic-imaging nanocarriers for triggered tumor delivery

Small (Weinheim An Der Bergstrasse, Germany), 8(18), 2895–2903.

By: J. Kim, H. Yuan, J. Nie, Y. Yang, M. Leggas, P. Potter, J. Rinehart, M. Jay, X. Lu

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Silver nanoparticles do not influence stem cell differentiation but cause minimal toxicity

NANOMEDICINE, 7(8), 1197–1209.

By: M. Samberg n, E. Loboa n, S. Oldenburg* & N. Monteiro-Riviere n

author keywords: in vitro; nanoparticles; nanotechnology; nanotoxicology; scaffolds; silver; stem cells
MeSH headings : Adipose Tissue / cytology; Adult; Cell Differentiation / drug effects; Cell Survival / drug effects; Cells, Cultured; Female; Humans; Metal Nanoparticles / toxicity; Metal Nanoparticles / ultrastructure; Silver / toxicity; Stem Cells / cytology; Stem Cells / drug effects; Young Adult
TL;DR: The biocompatibility of Ag-NPs with both undifferentiated and differentiated hASC establishes their suitability for incorporation into tissue-engineered graft scaffolds, for the prevention of bacterial contamination upon implantation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Phase Tuning, Thin Film Epitaxy, Interfacial Modeling, and Properties of YSZ-Buffered TiO2 on Si(001) Substrate

CRYSTAL GROWTH & DESIGN, 12(9), 4535–4544.

By: M. Bayati n, P. Gupta n, R. Molaei n, R. Narayan n & J. Narayant

UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2012 journal article

Microfabricated Arrays for Splitting and Assay of Clonal Colonies

ANALYTICAL CHEMISTRY, 84(24), 10614–10620.

By: P. Gach, W. Xu, S. King, C. Sims, J. Bear & N. Allbritton n

MeSH headings : Animals; Cell Separation / methods; Cells, Cultured; Clone Cells / cytology; Cloning, Molecular / methods; HeLa Cells; Humans; Mice; Microtechnology / methods; NIH 3T3 Cells
TL;DR: miniaturization and its parallel format enabled the identification and generation of 12 target clones from a starting sample of only 3900 cells and required only 5 man hours over 11 days, in contrast to the traditional method which required 500,000 cells and generated only 5 target clones. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2012 review

Integrating radioembolization into the treatment paradigm for metastatic neuroendocrine tumors in the liver

[Review of ]. American Journal of Clinical Oncology-Cancer Clinical Trials, 35(4), 393–398.

By: A. Kennedy, D. Coldwell, B. Sangro, H. Wasan & R. Salem

Source: NC State University Libraries
Added: August 6, 2018

2012 journal article

Dissolution-guided wetting for microarray and microfluidic devices

Lab on a Chip, 12(17), 3036–3039.

By: Y. Wang, C. Sims & N. Allbritton

Source: NC State University Libraries
Added: August 6, 2018

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