Works Published in 2016
Displaying works 61 - 80 of 173 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2016 journal article
Lumped-parameter electromyogram-driven musculoskeletal hand model: A potential platform for real-time prosthesis control
JOURNAL OF BIOMECHANICS, 49(16), 3901–3907.
author keywords: Wrist; Simulation; Amputation; Parameter; Optimization
MeSH headings : Adult; Artificial Limbs; Biomechanical Phenomena; Brain-Computer Interfaces; Electromyography / methods; Female; Forearm / physiology; Hand / physiology; Humans; Male; Metacarpophalangeal Joint / physiology; Models, Anatomic; Movement / physiology; Range of Motion, Articular / physiology; Robotics; Wrist Joint / physiology; Young Adult
TL;DR:
The results showed the promise of a lumped-parameter, EMG-driven musculoskeletal model for hand/wrist kinematic estimation, and might be useful for EMG control of powered upper limb prostheses, but more work is needed to demonstrate its online performance.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 journal article
Inflammation-Triggered Cancer Immunotherapy by Programmed Delivery of CpG and Anti-PD1 Antibody
ADVANCED MATERIALS, 28(40), 8912–8920.
MeSH headings : Adjuvants, Immunologic; Animals; Antibodies; CpG Islands; Immunotherapy; Inflammation; Mice; Neoplasms / therapy; Programmed Cell Death 1 Receptor / immunology
TL;DR:
Inflammation-triggered combination delivery of anti-PD-1 antibody and CpG oligodeoxynucleotides (CpG ODNs) has been demonstrated to prevent cancer relapse utilizing postsurgical inflammatory response.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Identification and isolation of antigen-specific cytotoxic T lymphocytes with an automated microraft sorting system
INTEGRATIVE BIOLOGY, 8(12), 1208–1220.
MeSH headings : Antigens, Viral / immunology; CD4-Positive T-Lymphocytes / immunology; CD8-Positive T-Lymphocytes / immunology; Cell Separation; Cells, Cultured; Epitope Mapping / instrumentation; Equipment Design; Equipment Failure Analysis; Humans; Immunoassay / instrumentation; Killer Cells, Natural / immunology; Lab-On-A-Chip Devices; T-Lymphocytes, Cytotoxic / immunology; Tissue Array Analysis / instrumentation
TL;DR:
A microraft array methodology is developed that automatically measures the ability of individual T cells to kill a population of target cells and viably sorts specific cells into a 96-well plate for expansion, enabling rapid identification of highly cytotoxic CD8+ T cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Muscle-spring dynamics in time-limited, elastic movements
author keywords: muscle-spring interaction; elastic energy storage; muscle dynamics; time-limited loading; fixed-end contraction; spring stiffness
MeSH headings : Animals; Biomechanical Phenomena; Grasshoppers / physiology; Movement; Muscle Contraction; Muscle, Skeletal / physiology; Ranidae / physiology; Tendons / physiology
TL;DR:
The findings demonstrate the significance of evolutionary variation in tendon and apodeme properties to realistic jumping contexts as well as the importance of considering the effect of muscle dynamics and behavioural constraints on energy storage in muscle–spring systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Maternal smoking impacts key biological pathways in newborns through epigenetic modification in Utero
BMC Genomics, 17.
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Engineered Nanoplatelets for Enhanced Treatment of Multiple Myeloma and Thrombus
ADVANCED MATERIALS, 28(43), 9573-+.
MeSH headings : Animals; Biomimetic Materials / chemistry; Biomimetic Materials / pharmacokinetics; Biomimetics; Blood Platelets / cytology; Bone and Bones / metabolism; Cell Line, Tumor; Cell Membrane / metabolism; Cellular Microenvironment; Disease Models, Animal; Drug Carriers / chemistry; Drug Carriers / pharmacokinetics; Humans; Mice; Multiple Myeloma / complications; Multiple Myeloma / drug therapy; Multiple Myeloma / metabolism; Multiple Myeloma / pathology; Nanoparticles / chemistry; Thrombosis / complications; Thrombosis / drug therapy
TL;DR:
A platelet-membrane-coated biomimetic nanocarrier, which can sequentially target the bone microenvironment and Myeloma cells to enhance the drug availability at the myeloma site and decrease off-target effects, is developed for inhibiting multiple myelomas growth and simultaneously eradicating thrombus complication.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Biological evaluation of ultrananocrystalline and nanocrystalline diamond coatings
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 27(12).
MeSH headings : Bone Marrow Cells / cytology; Cell Proliferation; Cell Survival; Coated Materials, Biocompatible / chemistry; Diamond / chemistry; Humans; Mesenchymal Stem Cells / cytology; Microscopy, Atomic Force; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Microwaves; Nanoparticles / chemistry; Nanostructures / chemistry; Polystyrenes / chemistry; Silicon / chemistry; Spectrum Analysis, Raman; Surface Properties
TL;DR:
Evaluated UNCD and NCD coatings demonstrate in vitro biocompatibility irrespective of surface topography, and cell viability, proliferation, and morphology responses of human bone marrow-derived mesenchymal stem cells to UNCDand NCD surfaces were evaluated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
intracellular trafficking network of protein nanocapsules: endocytosis, exocytosis and autophagy
Theranostics, 6(12), 2099–2113.
Source: NC State University Libraries
Added: August 6, 2018
2016 conference paper
The application of acoustic angiography to assess the progression of angiogenesis in a spontaneous mouse model of breast cancer
2016 IEEE International Ultrasonics Symposium (IUS). Presented at the 2016 IEEE International Ultrasonics Symposium (IUS).
Event: 2016 IEEE International Ultrasonics Symposium (IUS)
TL;DR:
Results indicate that acoustic angiography images can reveal microvasculature in sufficient detail for vascular morphology to be used as a biomarker for cancer imaging.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
2016 journal article
Synergistic Transcutaneous Immunotherapy Enhances Antitumor Immune Responses through Delivery of Checkpoint Inhibitors
ACS NANO, 10(9), 8956–8963.
author keywords: drug delivery; immunotherapy; anti-PD1; IDO; microneedle
MeSH headings : Animals; Cell Cycle Checkpoints / drug effects; Drug Delivery Systems; Immunosuppression Therapy; Immunotherapy / methods; Indoleamine-Pyrrole 2,3,-Dioxygenase / therapeutic use; Melanoma / therapy; Programmed Cell Death 1 Receptor / therapeutic use; Skin Neoplasms / therapy; Tumor Microenvironment
TL;DR:
This synergistic immunotherapy strategy locally targets the immunoinhibitory receptor programmed cell death protein 1 (PD1) and immunosuppressive enzyme indoleamine 2,3-dioxygenase (IDO) for the treatment of melanoma through a microneedle-based transcutaneous delivery approach and achieves potent antitumor efficacy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Strong Bioinspired Polymer Hydrogel with Tunable Stiffness and Toughness for Mimicking the Extracellular Matrix
ACS MACRO LETTERS, 5(11), 1217–1221.
TL;DR:
A biomimetic polymer hydrogel that incorporates strong intermolecular hydrogen bonding between urethane-urethane linkages as well as urethanes-ester linkages and provides biochemical and physical cues that support the three-dimensional proliferation of chondrocytes and osteogenic differentiation of preosteoblasts is reported on.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2016 conference paper
Reverberation clutter and sources of image degradation in transcostal imaging
2016 ieee international ultrasonics symposium (ius).
TL;DR:
The objective of this paper is to integrate the Fullwave nonlinear acoustic simulation tool with acoustical maps derived from the National Library of Medicine's Visible Human to generate highly realistic simulations of transcostal imaging.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2016 conference paper
On the quantitative potential of viscoelastic response (VisR) ultrasound using matrix array transducers: In silico demonstration
2016 ieee international ultrasonics symposium (ius).
Source: NC State University Libraries
Added: August 6, 2018
2016 conference paper
Molecular acoustic angiography: Comparison of contrast-to-tissue ratio with multi-pulse techniques and imaging multiple targeted microbubbles
2016 IEEE International Ultrasonics Symposium (IUS). Presented at the 2016 IEEE International Ultrasonics Symposium (IUS).
Event: 2016 IEEE International Ultrasonics Symposium (IUS)
TL;DR:
The contrast-to-tissue ratio (CTR) between superharmonic and multi-pulse molecular imaging is compared and images of microbubbles targeted to different biomarkers expressed by the vascular endothelial cells are presented.
(via Semantic Scholar)
Sources: NC State University Libraries, ORCID, Crossref
Added: August 6, 2018
2016 conference paper
Laser-generated-focused ultrasound transducers for microbubble-mediated, dual-excitation sonothrombolysis
2016 ieee international ultrasonics symposium (ius).
TL;DR:
In vitro test results showed that microbubble-mediated LGFU treatment can yield the lytic rate of approximately 2 mg/min, suggesting that LGFU transducers may be useful in precision highLytic rate sonothrombolysis.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2016 conference paper
Large coherent apertures: Improvements in deep abdominal imaging and fundamental limits imposed by clutter
2016 ieee international ultrasonics symposium (ius).
TL;DR:
It is hypothesize that using a larger active aperture will improve image quality even in the presence of clutter and demonstrate improved image quality as described by resolution and lesion detectability with growing aperture size up to the full extent of the 10 cm aperture.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
2016 journal article
Intracellular delivery and ultrasonic activation of folate receptor-targeted phase-change contrast agents in breast cancer cells in vitro
JOURNAL OF CONTROLLED RELEASE, 243, 69–77.
author keywords: Ultrasound; Phase-change contrast agent; Microbubble; Nanodroplet; Perfluorocarbon; Decafluorobutane; Octafluoropropane; Folate receptor; Breast cancer
MeSH headings : Breast Neoplasms / diagnostic imaging; Breast Neoplasms / metabolism; Cell Line, Tumor; Contrast Media / administration & dosage; Drug Delivery Systems; Female; Fluorocarbons / chemistry; Folate Receptors, GPI-Anchored / metabolism; Humans; MCF-7 Cells; Microscopy, Confocal; Particle Size; Tissue Distribution; Ultrasonics / methods
TL;DR:
Evidence for the intracellular delivery and ultrasound-stimulated activation of folate receptor (FR)-targeted phase-change contrast agents (PCCAs) in MDA-MB-231 and MCF-7 breast cancer cells in vitro is presented.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2016 journal article
Facilitating Teamwork in Adolescent and Young Adult Oncology
JOURNAL OF ONCOLOGY PRACTICE, 12(11), 1067-+.
MeSH headings : Adolescent; Adult; Communication; Cooperative Behavior; Humans; Interprofessional Relations; Male; Patient Care Team / organization & administration; Precursor B-Cell Lymphoblastic Leukemia-Lymphoma / drug therapy; Trust; Young Adult
TL;DR:
A case of a young adult patient in the days immediately after a cancer diagnosis illustrates the critical importance of three interrelated core coordinating mechanisms-closed-loop communication, shared mental models, and mutual trust-of teamwork in an adolescent and young adult multidisciplinary oncology team.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2016 conference paper
Cross-sectional comparison of in vivo viscoelastic response (VisR) ultrasound in lower limb muscles of boys with and without Duchenne muscular dystrophy
2016 ieee international ultrasonics symposium (ius).
TL;DR:
VisR results were consistent with temporally-matched functional testing using a hand-held dynamometer, and suggest that VisR imaging is relevant to delineating viscoelastic property alterations that are associated with dystrophic muscle degeneration in boys with DMD, in vivo.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018
2016 conference paper
Carotid plaque characterization with ARFI imaging: Blinded reader study
2016 ieee international ultrasonics symposium (ius).
TL;DR:
It is suggested that ARFI is capable of distinguishing soft from stiff compositional elements of atherosclerotic plaques and may be relevant to improving plaque risk assessment.
(via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018
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