Works Published in 2021
Displaying works 61 - 80 of 246 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2021 journal article
Dual-Frequency Intravascular Sonothrombolysis: An In Vitro Study
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 68(12), 3599–3607.
author keywords: Transducers; Acoustics; Ultrasonic imaging; Frequency measurement; Frequency control; Impedance; Broadband communication; Dual-frequency thrombolysis; intravascular ultrasound transducer; passive cavitation; sonothrombolysis
MeSH headings : Acoustics; Contrast Media; Microbubbles; Transducers; Ultrasonic Therapy
TL;DR:
A new broadband intravascular transducer is developed and tests indicated that the MB-mediated, dual-frequency (750+500 kHz) sonothrombolysis yields an 85% higher lysis rate compared with the single-frequency treatment, and the lysis Rate increases with the difference between the two frequency components.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: December 6, 2021
2021 article
Naloxone and nalmefene absorption delivered by hollow microneedles compared to intramuscular injection
Papich, M. G., & Narayan, R. J. (2021, November 24). DRUG DELIVERY AND TRANSLATIONAL RESEARCH.
author keywords: Microneedle; Opioid; Overdose; Naloxone; Nalmefene
MeSH headings : Analgesics, Opioid; Animals; Cross-Over Studies; Dogs; Humans; Injections, Intramuscular; Naloxone; Naltrexone / analogs & derivatives; Naltrexone / pharmacokinetics; Naltrexone / therapeutic use; Narcotic Antagonists
TL;DR:
These studies were designed to test the feasibility of using the hollow microneedle array as an effective method of naloxone and nalmefene delivery for emergency treatment of opioid-induced respiratory depression (OIRD) in people.
(via Semantic Scholar)
doi.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: December 6, 2021
2021 article
Next generation bioceramics
Narayan, R., Basu, B., Goel, A., Jones, J., & Jung, S. (2021, December 1). JOURNAL OF THE AMERICAN CERAMIC SOCIETY.
Source: Web Of Science
Added: December 6, 2021
2021 journal article
Direct comparison of angiogenesis in natural and synthetic biomaterials reveals that matrix porosity regulates endothelial cell invasion speed and sprout diameter
ACTA BIOMATERIALIA, 135, 260–273.
author keywords: Angiogenesis; Cell migration; Cell proliferation; Microfluidics; ECM; Endothelial cells; Chemotaxis; Hydrogels; Microvasculature; Sprouting Morphogenesis; Matrix porosity
MeSH headings : Animals; Biocompatible Materials / pharmacology; Endothelial Cells; Extracellular Matrix; Hydrogels / pharmacology; Mice; Neovascularization, Physiologic; Porosity
TL;DR:
Characterization of matrix properties and sprout morphometrics across these materials points to matrix porosity as a critical regulator of sprout invasion speed and diameter, supported by the observation that nanoporous DexVS hydrogels yielded endothelial cell sprouts that were not perfusable.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 29, 2021
2021 journal article
IN VIVO PORCINE AGED DEEP VEIN THROMBOSIS MODEL FOR TESTING ULTRASOUND-BASED THROMBOLYSIS TECHNIQUES
ULTRASOUND IN MEDICINE AND BIOLOGY, 47(12), 3447–3457.
author keywords: Thrombosis; Deep vein thrombosis; DVT; Clot retraction; Sub-acute clot; Non-invasive; Thrombolysis; In vivo
MeSH headings : Animals; Disease Models, Animal; Fibrinolytic Agents / therapeutic use; Swine; Thrombolytic Therapy; Thrombosis / drug therapy; Venous Thrombosis / diagnostic imaging
TL;DR:
It is shown that sub-acute clots can consistently be formed with a minimally invasive, percutaneous approach, and the clot formed in this study remained intact for at least 1 wk in all subjects.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 29, 2021
2021 journal article
Shared Control of a Powered Exoskeleton and Functional Electrical Stimulation Using Iterative Learning
FRONTIERS IN ROBOTICS AND AI, 8.
Contributors: V. Molazadeh*, Q. Zhang n , X. Bao *, B. Dicianno * & N. Sharma n
author keywords: exoskeleton; wearable robot; shared control; iterative learning; functional electrical stimulation (FES)
Sources: Web Of Science, ORCID
Added: November 29, 2021
2021 journal article
Experimental Data and PBPK Modeling Quantify Antibody Interference in PEGylated Drug Carrier Delivery
BULLETIN OF MATHEMATICAL BIOLOGY, 83(12).
author keywords: PBPK model; Latin hypercube sampling; Parameter optimization; Anti-PEG antibodies; PEGylated liposomes
MeSH headings : Animals; Drug Carriers; Mathematical Concepts; Mice; Models, Biological; Polyethylene Glycols / pharmacokinetics; Positron Emission Tomography Computed Tomography; Tissue Distribution
TL;DR:
Near-continuous experimental measurements of PL concentration during the first hour post-injection from the liver, spleen, kidney, muscle, lung, and blood plasma, are used as truth sets with LHS to infer optimal parameter ranges for the full PBPK model.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 23, 2021
2021 article
Digital light processing-based 3D printing of polytetrafluoroethylene solid microneedle arrays
Sachan, R., Nguyen, A. K., Lu, J., Erdmann, D., Zhang, J. Y., & Narayan, R. J. (2021, November 9). MRS COMMUNICATIONS.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 23, 2021
2021 article
A Data-Driven Reinforcement Learning Solution Framework for Optimal and Adaptive Personalization of a Hip Exoskeleton
2021 IEEE INTERNATIONAL CONFERENCE ON ROBOTICS AND AUTOMATION (ICRA 2021), pp. 10610–10616.
author keywords: Exoskeleton; reinforcement learning; optimal adaptive control; least square policy iteration; data driven
TL;DR:
The results showed that the optimal and adaptive RL controller as a new approach was feasible for tuning assistive torque profile of the hip exoskeleton that coordinated with human actions and reduced activation level of hip extensor muscle in human.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: November 21, 2021
2021 journal article
Age-related changes to triceps surae muscle-subtendon interaction dynamics during walking
SCIENTIFIC REPORTS, 11(1).
MeSH headings : Achilles Tendon / physiology; Adult; Age Factors; Aged; Aging; Ankle Joint / physiology; Biomechanical Phenomena; Humans; Middle Aged; Muscle, Skeletal / physiology; Musculoskeletal Physiological Phenomena; Tendons / physiology; Walking; Young Adult
TL;DR:
The findings suggest that the capacity for sliding between subtendons may facilitate independent TS muscleActuation in young adults but may restrict that actuation in older adults, likely contributing to reduced push-off intensity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 15, 2021
2021 article
Age- and sex-specific differences in ACL and ACL bundle size during adolescent growth
Cone, S. G., Barnes, R. H., Howe, D., Fordham, L. A., Fisher, M. B., & Spang, J. T. (2021, November 2). JOURNAL OF ORTHOPAEDIC RESEARCH.
author keywords: ACL; bundles; growth; MRI; pediatrics
MeSH headings : Adolescent; Animals; Anterior Cruciate Ligament / diagnostic imaging; Anterior Cruciate Ligament Injuries; Child; Female; Humans; Magnetic Resonance Imaging / methods; Male; Models, Animal; Retrospective Studies
TL;DR:
Findings in the length and cross‐sectional area (CSA) of the ACL and its primary bundles in adolescent human subjects may point toward biomechanical changes in the adolescent human ACL.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: November 15, 2021
2021 article
Extracellular Matrix Hydrogels Promote Expression of Muscle-Tendon Junction Proteins
Gaffney, L. S., Davis, Z. G., Mora-Navarro, C., Fisher, M. B., & Freytes, D. O. (2021, November 2). TISSUE ENGINEERING PART A, Vol. 11.
author keywords: extracellular matrix; engineered tissues; myotendinous junction; paxillin
MeSH headings : Collagen / metabolism; Collagen Type I / metabolism; Culture Media, Conditioned; Extracellular Matrix / metabolism; Hydrogels; Muscles; Paxillin / metabolism; Tendons / metabolism
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: November 15, 2021
2021 journal article
Enhanced Vapor Transmission Barrier Properties via Silicon-Incorporated Diamond-Like Carbon Coating
POLYMERS, 13(20).
author keywords: coating; surface structure; moisture vapor transmission; silicon-incorporated diamond-like carbon; plasma-enhanced chemical vapor deposition; water stability
TL;DR:
Reducing the moisture vapor transmission through a commercial polymer bag material using a silicon-incorporated diamond-like carbon (Si-DLC) coating that was deposited using plasma-enhanced chemical vapor deposition is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: November 15, 2021
2021 article
Sex-specific biomechanics and morphology of the anterior cruciate ligament during skeletal growth in a porcine model
Howe, D., Cone, S. G., Piedrahita, J. A., Collins, B., Fordham, L. A., Griffith, E. H., … Fisher, M. B. (2021, November 9). JOURNAL OF ORTHOPAEDIC RESEARCH.
author keywords: anterior cruciate ligament; knee; porcine model; skeletal growth
MeSH headings : Adolescent; Aged; Animals; Anterior Cruciate Ligament; Anterior Cruciate Ligament Injuries; Biomechanical Phenomena; Child; Female; Humans; Joint Instability; Knee Joint; Male; Swine; Tibia
TL;DR:
A porcine model is used to investigate the sex-specific morphology and biomechanics of the ACL and its bundles throughout skeletal growth and has implications for age and sex‐specific surgical intervention strategies and suggests the need for human studies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
5. Gender Equality
(Web of Science)
Source: Web Of Science
Added: November 15, 2021
2021 journal article
Detection of Chloride Using Microelectrodes in Closed Bipolar Electrode Scheme
ECS Meeting Abstracts.
Source: ORCID
Added: November 12, 2021
2021 journal article
Enhanced nucleation and large-scale growth of CVD diamond via surface-modification of silicon-incorporated diamond-like carbon thin films
DIAMOND AND RELATED MATERIALS, 120.
author keywords: Micro-diamond; Thin film; Surface modification; Silicon-incorporated diamond-like carbon
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 8, 2021
2021 review
Applications of sub-micron low-boiling point phase change contrast agents for ultrasound imaging and therapy
[Review of ]. CURRENT OPINION IN COLLOID & INTERFACE SCIENCE, 56.
author keywords: Nanodroplet; Perfluorocarbon; Contrast agent; Phase change; Perfluorobutane; Perfluoropropane; Phase shift
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 8, 2021
2021 article
3D Printing of Polytetrafluoroethylene Hollow Needles for Medical Applications
Sachan, R., Sachan, A., Lu, J., Erdmann, D., Zhang, J. Y., & Narayan, R. J. (2021, October 28). JOM.
TL;DR:
DLP-based 3D printing of polytetrafluoroethylene may be an appropriate approach for producing needle arrays and other technologically relevant devices.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: November 8, 2021
2021 journal article
Age-related differences in calf muscle recruitment strategies in the time-frequency domain during walking as a function of task demand
JOURNAL OF APPLIED PHYSIOLOGY, 131(4), 1348–1360.
author keywords: activation; elderly; electromyography; frequency; plantar flexor
MeSH headings : Aged; Ankle; Electromyography; Humans; Muscle, Skeletal; Walking; Walking Speed; Young Adult
TL;DR:
The results implicate GAS time-frequency content, and its morphological and neural origins, as a potential determinant of hallmark ankle push-off deficits due to aging, particularly at faster walking speeds.
(via Semantic Scholar)
Source: Web Of Science
Added: November 1, 2021
2021 journal article
Light-guided sectioning for precise in situ localization and tissue interface analysis for brain-implanted optical fibers and GRIN lenses
CELL REPORTS, 36(13).
MeSH headings : Animals; Brain / physiology; Head / physiology; Lens, Crystalline / physiology; Lenses; Mice; Neurons / physiology; Optical Fibers; Photons; Refractometry / methods
TL;DR:
A three-dimensional post hoc histology method called “light-guided sectioning” (LiGS), which preserves the tissue with its optical implant in place and allows staining and clearing of a volume up to 500 μm in depth, is developed.
(via Semantic Scholar)
Source: Web Of Science
Added: October 26, 2021
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