Works Published in 2016

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Displaying works 81 - 100 of 173 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2016 conference paper

Adaptive windowing in mechanically-steered intravascular ultrasound imaging: Ex vivo and in vivo studies with contrast enhancement

2016 ieee international ultrasonics symposium (ius).

TL;DR: Processing techniques for improving spatial resolution and image contrast in mechanically steered ultrasound imaging based on minimum variance (MV) beamforming and the phase coherence factor (PCF) are presented and may improve image quality in both conventional B-mode IVUS and contrast-enhanced IVUS. (via Semantic Scholar)
Source: NC State University Libraries
Added: August 6, 2018

2016 conference paper

A dual-frequency endoscopic transducer for imaging vascular invasion in pancreatic cancer

2016 ieee international ultrasonics symposium (ius).

TL;DR: The development of a single element dual-frequency transducer for rotational endoscopic imaging designed to operate at 4/20 MHz to image microbubble superharmonics is described, suggesting such a device may be suitable for direct visualization of small vessels from within the lumen of larger vessels such as the portal vein. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2016 conference paper

A dual-frequency co-linear array for prostate acoustic angiography

2016 ieee international ultrasonics symposium (ius).

TL;DR: The development of a dual layer co-linear array ultrasound transducer for transrectal acoustic angiography is described, suggesting that the prototype co- linear array is capable of performing dual-frequency superharmonic imaging of microbubbles for prostate cancer assessment. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: NC State University Libraries
Added: August 6, 2018

2016 review

The Age-Associated Reduction in Propulsive Power Generation in Walking

[Review of ]. EXERCISE AND SPORT SCIENCES REVIEWS, 44(4), 129–136.

By: J. Franz n

author keywords: plantarflexor; biomechanics; gait; elderly; ankle; geriatrics; ultrasound
MeSH headings : Aged; Aged, 80 and over; Aging / physiology; Biomechanical Phenomena; Gait / physiology; Humans; Muscle Weakness / physiopathology; Muscle, Skeletal / physiology; Postural Balance / physiology; Range of Motion, Articular / physiology; Tendons / physiology; Walking / physiology
TL;DR: The hypothesis that declines in force or power generating capacity of propulsive leg muscles cannot fully explain the age-related reduction in propulsive power generation during walking is examined. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Single-Step Fabrication of Computationally Designed Microneedles by Continuous Liquid Interface Production

PLOS ONE, 11(9).

By: A. Johnson n, C. Caudill*, J. Tumbleston*, C. Bloomquist*, K. Moga*, A. Ermoshkin*, D. Shirvanyants*, S. Mecham*, J. Luft*, J. DeSimone n

MeSH headings : Acrylates / pharmacology; Animals; Drug Delivery Systems / methods; Fluorescent Dyes / pharmacology; Mice, Nude; Microinjections; Permeability / drug effects; Skin Absorption / drug effects
TL;DR: A novel additive manufacturing technique called Continuous Liquid Interface Production (CLIP) is utilized to rapidly prototype sharp microneedles with tuneable geometries (size, shape, aspect ratio, spacing) that effectively pierced murine skin ex vivo and released the fluorescent drug surrogate rhodamine. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Mechanical and Vascular Cues Synergistically Enhance Osteogenesis in Human Mesenchymal Stem Cells

TISSUE ENGINEERING PART A, 22(15-16), 997–1005.

Contributors: A. Steward n, J. Cole n, F. Ligler n & E. Loboa n

MeSH headings : Adolescent; Adult; Antigens, Differentiation / biosynthesis; Coculture Techniques; Endothelial Cells / cytology; Endothelial Cells / metabolism; Female; Humans; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Neovascularization, Physiologic; Osteogenesis
TL;DR: The concurrent application of strain to an MSC-EC co- culture resulted in a significant increase in calcium accretion and mineral deposition, suggesting that co-culture and strain synergistically enhance osteogenesis. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2016 article

Low-Power Wearable Systems for Continuous Monitoring of Environment and Health for Chronic Respiratory Disease

Dieffenderfer, J., Goodell, H., Mills, S., McKnight, M., Yao, S., Lin, F., … Bozkurt, A. (2016, September). IEEE JOURNAL OF BIOMEDICAL AND HEALTH INFORMATICS, Vol. 20.

By: J. Dieffenderfer n, H. Goodell n, S. Mills n, M. McKnight n, S. Yao n, F. Lin n, E. Beppler n, B. Bent n ...

author keywords: Environmental and physiological sensing; wearable asthma monitoring
MeSH headings : Asthma / diagnosis; Chronic Disease; Electric Impedance; Electrocardiography; Equipment Design; Humans; Monitoring, Ambulatory / instrumentation; Monitoring, Ambulatory / methods; Photoplethysmography; Skin / physiopathology; Spirometry
TL;DR: The preliminary efforts to achieve a submilliwatt system ultimately powered by the energy harvested from thermal radiation and motion of the body are described with the primary contributions being an ultralow-power ozone sensor, an volatile organic compounds sensor, spirometer, and the integration of these and other sensors in a multimodal sensing platform. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Genetic predictors of cardiovascular mortality during intensive glycemic control in type 2 diabetes: Findings from the ACCORD clinical trial

Diabetes Care, 39(11), 1915–1924.

By: H. Shah, H. Gao, M. Morieri, J. Skupien, S. Marvel, G. Pare, G. Mannino, P. Buranasupkajorn ...

Source: NC State University Libraries
Added: August 6, 2018

2016 journal article

Enhanced cellular infiltration of human adipose-derived stem cells in allograft menisci using a needle-punch method

Journal of Orthopaedic Surgery and Research, 11(1), 132.

By: R. Nordberg, A. Charoenpanich, C. Vaughn, E. Griffith, M. Fisher, J. Cole, J. Spang, E. Loboa

Sources: NC State University Libraries, ORCID
Added: August 6, 2018

2016 journal article

On the Quantitative Potential of Viscoelastic Response (VisR) Ultrasound Using the One-Dimensional Mass-Spring-Damper Model

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 63(9), 1276–1287.

By: M. Selzo n, C. Moore n, M. Hossain n, M. Palmeri* & C. Gallippi n

author keywords: Acoustic radiation force (ARF); mass spring damper (MSD); viscoelasticity; viscoelastic response (VisR) ultrasound
MeSH headings : Acoustics; Elastic Modulus; Humans; Mechanical Phenomena; Ultrasonography; Viscosity
TL;DR: The results suggest VisR's potential relevance to quantifying viscoelastic properties clinically and suggest the feasibility of corrected VisR imaging in vivo in the rectus femoris muscle of an adult with no known neuromuscular disorders is suggested. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

On the Feasibility of Quantifying Fibrous Cap Thickness With Acoustic Radiation Force Impulse (ARFI) Ultrasound

IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 63(9), 1262–1275.

author keywords: Acoustic radiation force; acoustic radiation force impulse (ARFI); atherosclerosis; fibrous cap (FC); finite-element method (FEM); resolution; vulnerable plaque
MeSH headings : Carotid Arteries / diagnostic imaging; Elasticity Imaging Techniques; Humans; Motion; Plaque, Atherosclerotic / diagnostic imaging; Ultrasonography
TL;DR: The results of this study demonstrate that tracking pulse frequencies around 12 MHz are necessary to resolve caps around 0.2 mm; large motion-tracking kernel sizes introduce bias into thickness measurements and overestimate the true cap thickness; and color saturation settings on ARFI peak displacement images can impact thickness measurement accuracy substantially. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Immediate effect of vibratory stimuli on quadriceps function in healthy adults

MUSCLE & NERVE, 54(3), 469–478.

By: D. Pamukoff*, B. Pietrosimone*, M. Lewek*, E. Ryan*, P. Weinhold n, D. Lee*, J. Blackburn*

author keywords: cortical; Hoffmann reflex; muscle; neuron; quadriceps; strength
MeSH headings : Adolescent; Analysis of Variance; Electromyography; Ergometry; Evoked Potentials, Motor / physiology; Female; H-Reflex / physiology; Healthy Volunteers; Humans; Isometric Contraction / physiology; Male; Motor Neurons / physiology; Muscle Strength Dynamometer; Physical Stimulation; Quadriceps Muscle / physiology; Time Factors; Vibration; Young Adult
TL;DR: WBV and LMV increased quadriceps function and may be used to enhance the efficacy of strengthening protocols, and EMG amplitude was greater than control after application. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Development of a protease-resistant reporter to quantify BCR-ABL activity in intact cells

ANALYST, 141(21), 6008–6017.

By: A. Proctor*, I. Zigoneanu n, Q. Wang*, C. Sims*, D. Lawrence* & N. Allbritton n

MeSH headings : Animals; Cell Line, Tumor; Fusion Proteins, bcr-abl / metabolism; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Peptide Hydrolases / metabolism; Peptides / metabolism; Phosphorylation; Protein-Tyrosine Kinases / metabolism; Substrate Specificity
TL;DR: A peptidase-resistant ABL kinase substrate was developed by identifying protease-susceptible bonds on an ABL substrate peptide and replacing flanking amino acids with non-native amino acids, and the designed peptide X-A acts as a long-lived BCR-ABL kinase reporter in the leukemic cells possessing the BCR/ABL mutation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

An Integrated Chemical Cytometry Method: Shining a Light on Akt Activity in Single Cells

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 55(42), 13095–13098.

By: E. Mainz*, Q. Wang*, D. Lawrence* & N. Allbritton n

author keywords: biosensors; chemical cytometry; kinase activity probes; photochemistry; single-cell analysis
MeSH headings : Biosensing Techniques; Cell Line, Tumor; Flow Cytometry; Humans; Proto-Oncogene Proteins c-akt / metabolism; Single-Cell Analysis
TL;DR: An integrated analysis system that utilizes a light-programmable, cell-permeable reporter deliverable simultaneously to many cells that enables programmable reaction times within the cell cytoplasm to evaluate oncogenic kinase activity in small clinical samples. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

A multinuclear metal complex based dnase-mimetic artificial enzyme: Matrix cleavage for combating bacterial biofilms

Angewandte Chemie [International Edition in English], 55(36), 10732–10736.

By: Z. Chen, H. Ji, C. Liu, W. Bing, Z. Wang & X. Qu

Source: NC State University Libraries
Added: August 6, 2018

2016 review

Review of Automated Microinjection Systems for Single Cells in the Embryogenesis Stage

[Review of ]. IEEE-ASME TRANSACTIONS ON MECHATRONICS, 21(5), 2391–2404.

By: S. Permana n, E. Grant n, G. Walker n & J. Yoder n

author keywords: Automation; biological cells; control system; mechatronics; reviews
TL;DR: A comprehensive review of the major research technologies used in automated cell microin injection and of their individual subsystems concludes that research into automated microinjection systems will focus on reducing the scale of microinject systems and developing appropriate controllers. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Nanosecond Time-Resolution Study of Gold Nanorod Rotation at the Liquid-Solid Interface

CHEMPHYSCHEM, 17(14), 2218–2224.

author keywords: adsorption; fluctuation correlation spectroscopy; gold nanorods; rotation; surface plasmon resonance
TL;DR: This nanosecond time-resolution study reveals that the apparent continuous rotation of gold nanorods actually consists of numerous fast, intermittent rotations or transitions between a small number of weakly immobilized states, with the particle resting in the immobilization states most of the time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Microvessel manifold for perfusion and media exchange in three-dimensional cell cultures

Biomicrofluidics, 10(5), 054109.

By: S. Roberts*, K. DiVito*, F. Ligler n, A. Adams* & M. Daniele n

TL;DR: An inclusive on-chip platform that is capable of maintaining laminar flow through porous biosynthetic microvessels and characterize the diffusion of small molecules from the perfusate, across the microvessel wall, and into the matrix of a 3D cell culture is developed. (via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: August 6, 2018

2016 review

Mechanical Force-Triggered Drug Delivery

[Review of ]. CHEMICAL REVIEWS, 116(19), 12536–12563.

By: Y. Zhang n, J. Yu n, H. Bomba n, Y. Zhu n & Z. Gu n

MeSH headings : Animals; Drug Carriers / chemistry; Drug Carriers / pharmacology; Drug Delivery Systems / methods; Liposomes / chemistry; Liposomes / pharmacology; Magnetic Phenomena; Mechanical Phenomena; Microbubbles; Nanoparticles / chemistry; Ultrasonic Waves
TL;DR: An overview of recent advances in mechanically activated DDS is provided and the opportunities and challenges regarding clinical translations are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2016 journal article

Evaluation of Silver Ion-Releasing Scaffolds in a 3D Coculture System of MRSA and Human Adipose-Derived Stem Cells for Their Potential Use in Treatment or Prevention of Osteomyelitis

TISSUE ENGINEERING PART A, 22(21-22), 1258–1263.

By: M. Mohiti-Asli n, C. Molina n, T. Diteepeng*, B. Pourdeyhimi n & E. Loboa n

author keywords: nanofiber; antimicrobial; coculture; osteomyelitis
MeSH headings : Adipose Tissue / metabolism; Cell Differentiation / drug effects; Coculture Techniques; Humans; Methicillin-Resistant Staphylococcus aureus / growth & development; Osteogenesis / drug effects; Osteomyelitis / prevention & control; Silver / chemistry; Silver / pharmacokinetics; Silver / pharmacology; Stem Cells / metabolism; Tissue Scaffolds / chemistry
TL;DR: It is suggested that these biocompatible, degradable, silver ion-releasing scaffolds can be used at an infection site to treat osteomyelitis and/or to coat bone implants as a preventative measure against infection postsurgery. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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