Works Published in 2020

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Displaying works 81 - 100 of 216 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

Improving the heating efficiency of high intensity focused ultrasound ablation through the use of phase change nanodroplets and multifocus sonication

PHYSICS IN MEDICINE AND BIOLOGY, 65(20).

By: A. Singh*, A. Nyankima n, M. Anthony Phipps*, V. Chaplin*, P. Dayton n & C. Caskey*

author keywords: high intensity focused ultrasound; ablation; focal steering; phase-shift nanodroplets; non-invasive therapy
MeSH headings : High-Intensity Focused Ultrasound Ablation / methods; Hot Temperature; Humans; Liver / surgery; Nanotechnology; Sonication
TL;DR: Methods for using phase-shift nanodroplets with multi-focus sonications to enhance volumetric ablation and ablation efficiency at constant powers while increasing the pre-focal temperature by less than 6 ∘C are described. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: October 26, 2020

2020 journal article

A Biomechanical Comparison of Modified Radioscapholunate Fusion Constructs for Radiocarpal Arthritis

JOURNAL OF HAND SURGERY-AMERICAN VOLUME, 45(10).

By: J. Shapiro*, S. Feinstein*, E. Jewell*, R. Taylor n, P. Weinhold n & R. Draeger*

author keywords: Biomechanical performance; cadaveric model; headless screws; pin plates; plates and screws
MeSH headings : Arthritis; Arthrodesis; Biomechanical Phenomena; Bone Plates; Bone Screws; Cadaver; Humans; Wrist Joint / surgery
TL;DR: Plate-and-screw and pin-plate constructs are biomechanically superior in resisting RSL distraction compared with headless compression screws for RSL arthrodesis over 6 weeks of simulated ROM in the absence of healing. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: October 26, 2020

2020 conference paper

Knowledge-Guided Reinforcement Learning Control for Robotic Lower Limb Prosthesis

2020 IEEE International Conference on Robotics and Automation (ICRA), 754–760.

TL;DR: The knowledge-guided Q-learning (KG-QL) control method is proposed as a principled way for Reinforcement learning (RL) control and its feasibility is demonstrated by employing OpenSim, a well-established human locomotion simulator. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: October 22, 2020

2020 conference paper

Stiffness Perception using Transcutaneous Electrical Stimulation during Active and Passive Prosthetic Control

2020 42nd Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), 2020-July, 3909–3912.

MeSH headings : Arm; Artificial Limbs; Electric Stimulation; Hand; Transcutaneous Electric Nerve Stimulation
TL;DR: The results showed that the accuracy of object stiffness recognition was similar in both active and passive conditions, which indicated that the sensorimotor integration processes could affect haptic perception for some users. (via Semantic Scholar)
Source: ORCID
Added: October 22, 2020

2020 journal article

Perceiving amputee gait from biological motion: kinematics cues and effect of experience level

Scientific Reports, 10(1).

By: I. Lee n, M. Pacheco*, M. Lewek* & H. Huang n

Contributors: I. Lee n, M. Pacheco*, M. Lewek* & H. Huang n

MeSH headings : Adult; Aged; Amputees; Animals; Artificial Limbs; Biomechanical Phenomena; Clinical Competence; Cues; Gait / physiology; Gait Disorders, Neurologic / diagnosis; Gait Disorders, Neurologic / physiopathology; Humans; Leg; Male; Middle Aged; Movement; Physical Therapists; Video Recording
TL;DR: A new method that combines biological motion and principal component analysis to gradually mesh amputee and typical walking patterns showed that on average the accuracy rate in identifying gait deviations between PT and PTS was similar and better than Novices. (via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Source: ORCID
Added: October 22, 2020

2020 conference paper

Evaluation of Activities of Daily Living Tesbeds for Assessing Prosthetic Device Usability

2020 IEEE International Conference on Human-Machine Systems (ICHMS).

TL;DR: Findings suggest that the clothespin relocation task (CRT) and Southampton hand assessment protocol (SHAP) are the most sensitive testbeds for usability assessment of upper-limb prosthetic devices and these tasks require similar limb movements to high frequency ADLs. (via Semantic Scholar)
Source: ORCID
Added: October 22, 2020

2020 journal article

Human-prosthesis coordination: A preliminary study exploring coordination with a powered ankle-foot prosthesis

Clinical Biomechanics, 80, 105171.

By: B. Fylstra n, I. Lee n, S. Huang n, A. Brandt n, M. Lewek* & H. Huang n

Contributors: B. Fylstra n, I. Lee n, S. Huang n, A. Brandt n, M. Lewek* & H. Huang n

author keywords: Transtibial amputee; Human-prosthesis interface; Powered ankle-foot prosthesis; Human-prosthesis interaction
MeSH headings : Adult; Amputees; Ankle; Artificial Limbs; Biomechanical Phenomena; Female; Foot; Gait; Humans; Male; Mechanical Phenomena; Prosthesis Design
TL;DR: Results from this preliminary study highlight the need for future work to systematically quantify the coordination between the human and powered prosthesis and understand how such coordination at the joint level influences overall gait efficiency. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: October 22, 2020

2020 journal article

OPTIMAL EMG PLACEMENT FOR A ROBOTIC PROSTHESIS CONTROLLER WITH SEQUENTIAL, ADAPTIVE FUNCTIONAL ESTIMATION (SAFE)

ANNALS OF APPLIED STATISTICS, 14(3), 1164–1181.

By: J. Stallrich*, M. Islam, A. Staicu*, D. Crouch*, L. Pan* & H. Huang*

Contributors: J. Stallrich*, N. Islam, A. Staicu*, D. Crouch*, L. Pan* & H. Huang*

author keywords: Electromyography signal; varying functional regression; functional variable selection; adaptive group LASSO; correlated functional predictors; sequential adaptive functional estimation
TL;DR: A novel decoder based on a dynamic, functional linear model with velocity or acceleration as its response and the recent past EMG signals as functional covariates is proposed, increasing the predictive capability of a single EMG signal compared to existing decoders. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 19, 2020

2020 personal communication

Reply

Loeser, R. F., Collins, J. A., Diekman, B. O., & Carlson, C. S. (2020, December).

MeSH headings : Animals; Mice; Osteoarthritis
TL;DR: Results indicated that knockout of JNK signaling is able to promote senescence in joint tissues and up-regulate the severity of age-related OA, which shows the potential of targeting J NK signaling to treat OA. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 19, 2020

2020 journal article

Modulation of finger muscle activation patterns across postures is coordinated across all muscle groups

JOURNAL OF NEUROPHYSIOLOGY, 124(2), 330–341.

By: S. Lee*, D. Qiu*, H. Fischer*, M. Conrad* & D. Kamper n

author keywords: activation patterns; extrinsic and intrinsic hand muscles; index finger; motor control
MeSH headings : Adult; Biomechanical Phenomena / physiology; Electromyography; Female; Fingers / physiology; Humans; Male; Motor Activity / physiology; Muscle, Skeletal / physiology; Posture / physiology; Young Adult
TL;DR: Modulation of activation levels of the extrinsic hand muscles, particularly the extensors, were as great as those of intrinsic muscles, suggesting that both extrinsics/intrinsic muscles were involved in creating the desired forces. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Head Impact Telemetry System's Video-based Impact Detection and Location Accuracy

MEDICINE AND SCIENCE IN SPORTS AND EXERCISE, 52(10), 2198–2206.

author keywords: HEAD INJURIES; CONCUSSION; AMERICAN FOOTBALL; INJURY PREVENTION; HEAD IMPACTS
TL;DR: Data is provided on the HIT System’s impact detection and location accuracy during high school football special teams plays using game video analysis that has not been previously published and it is believed that the HIT system is useful for estimating population-based impact location distributions for special teams play. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2020

2020 journal article

A COMPARISON OF SONOTHROMBOLYSIS IN AGED CLOTS BETWEEN LOWBOILING-POINT PHASE-CHANGE NANODROPLETS AND MICROBUBBLES OF THE SAME COMPOSITION

ULTRASOUND IN MEDICINE AND BIOLOGY, 46(11), 3059–3068.

author keywords: Sonothrombolysis; Nanodroplets; Microbubbles; Cavitation; Clot
MeSH headings : Animals; Cattle; Mechanical Thrombolysis / methods; Microbubbles; Nanostructures; Thrombosis / therapy; Time Factors; Transition Temperature; Ultrasonic Therapy
TL;DR: Enhanced cavitation erosion of blood clots exposed to low-boiling-point (-2°C) perfluorocarbon phase-change nanodroplets and pulsed ultrasound, as well as microbubbles with the same formulation under the same conditions are presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2020

2020 review

Gradient scaffolds for osteochondral tissue engineering and regeneration

[Review of ]. JOURNAL OF MATERIALS CHEMISTRY B, 8(36), 8149–8170.

MeSH headings : Animals; Bone Regeneration / physiology; Bone and Bones / physiology; Cartilage / physiology; Chondrocytes / physiology; Humans; Mesenchymal Stem Cells / physiology; Osteoblasts / physiology; Porosity; Printing, Three-Dimensional; Tissue Engineering / methods; Tissue Scaffolds / chemistry
TL;DR: An overview of both discrete and continuous gradient OC tissue scaffolds in terms of cell type, scaffold material, microscale structure, mechanical properties, fabrication methods, and scaffold stimuli is provided. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Buckle-Delamination-Enabled Stretchable Silver Nanowire Conductors

ACS APPLIED MATERIALS & INTERFACES, 12(37), 41696–41703.

By: S. Wu n, S. Yao n, Y. Liu n, X. Hu*, H. Huang* & Y. Zhu n

Contributors: S. Wu n, S. Yao n, Y. Liu n, X. Hu*, H. Huang* & Y. Zhu n

author keywords: stretchable conductor; silver nanowire; buckling; buckle-delamination; wrinkling; thermochromic
TL;DR: A theoretical model on the buckle-delamination structure is developed to predict the geometrical evolution, and an integrated silver nanowire/elastomer sensing module and a stretchable thermochromic device are developed to demonstrate the utility of the stretchable conductor. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID, NC State University Libraries
Added: October 12, 2020

2020 review

Challenges & opportunities for phage-based in situ microbiome engineering in the gut

[Review of Challenges & opportunities for phage-based in situ microbiome engineering in the gut]. JOURNAL OF CONTROLLED RELEASE, 326, 106–119.

By: P. Voorhees*, C. Cruz-Teran*, J. Edelstein n & S. Lai n

author keywords: Bacteriophage; Phage; Microbiome; Microbiome engineering; in situ engineering; Microbiome gene therapy
MeSH headings : Bacteria; Bacteriophages; Gastrointestinal Microbiome; Humans; Microbiota
TL;DR: The challenges and opportunities associated with engineering bacteriophages to control and manipulate the gut microbiome are presented and areakin to human gene therapies delivered by viral vectors. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Development of Biomimetic Antimicrobial Platelet-Like Particles Comprised of Microgel Nanogold Composites

REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE, 6(3), 299–309.

By: E. Sproul n, S. Nandi n, E. Chee n, S. Sivadanam n, B. Igo n, L. Schreck*, A. Brown n

author keywords: Synthetic platelet; Fibrin; Hemostatic material; Trauma; Antimicrobial material; Microgels
TL;DR: These results demonstrate NGCs fabricated through noncovalent and covalent methods retain deformability necessary for clot collapse and exhibit some antimicrobial potential, and are promising materials for preventing blood loss and infection following traumatic injury. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Locally delivered minocycline microspheres do not impair osseointegration of titanium implants in a rat femur model

JOURNAL OF ORTHOPAEDICS, 20, 213–216.

By: J. Shapiro*, S. AbuMoussa*, C. Lindsay*, G. Mason*, L. Dahners* & P. Weinhold n

author keywords: Minocycline; Osseointegration; Pushout testing; Bone volume fraction; Sprague-Dawley
TL;DR: Peri-IMplant minocycline administration did not impair implant fixation strength or peri-implant bone-volume, supporting its potential utility as an adjunct to intramedullary implants. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 12, 2020

2020 journal article

Creation of a novel DET type FAD glucose dehydrogenase harboring Escherichia coli derived cytochrome b562 as an electron transfer domain

Biochemical and Biophysical Research Communications, 530(1), 82–86.

By: T. Yanase*, J. Okuda-Shimazaki n, K. Mori*, K. Kojima*, W. Tsugawa* & K. Sode n

author keywords: Fusion enzymes; Direct electron transfer; Enzyme electrode; 3rd generation glucose sensor; Cytochrome b(562); FAD-Dependent glucose dehydrogenase
MeSH headings : Botrytis / genetics; Botrytis / metabolism; Cytochrome b Group / genetics; Cytochrome b Group / metabolism; Electron Transport; Escherichia coli / genetics; Escherichia coli / metabolism; Escherichia coli Proteins / genetics; Escherichia coli Proteins / metabolism; Flavin-Adenine Dinucleotide / metabolism; Glucose 1-Dehydrogenase / genetics; Glucose 1-Dehydrogenase / metabolism; Protein Engineering; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / metabolism; Substrate Specificity
TL;DR: The construction and production of a new DET-type FADGDH is demonstrated using E.coli as the host cells, which is advantageous for future industrial application and further engineering. (via Semantic Scholar)
Source: ORCID
Added: October 9, 2020

2020 review

Minimally Invasive Platforms in Biosensing

[Review of ]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY, 8.

author keywords: transdermal biosensing; microfabrication; microfluidics; microneedle; luminescent sensors; fluorescent biosensors
TL;DR: Recent advancements related to minimally invasive platform for biosensing are reviewed and the use of capillary action in microneedle-assisted biosensing may facilitate the detection of analytes in body fluids. (via Semantic Scholar)
Source: Web Of Science
Added: October 5, 2020

2020 journal article

Dermal Extracellular Matrix-Derived Hydrogels as an In Vitro Substrate to Study Mast Cell Maturation

Tissue Engineering Part A.

Emily Ozpinar

MeSH headings : Animals; Cell Differentiation; Collagen; Extracellular Matrix; Humans; Hydrogels; Mast Cells; Swine
Source: ORCID
Added: October 4, 2020

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