Biomedical Engineering

Works Published in 2011

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Displaying works 101 - 113 of 113 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

3-D MICROVESSEL-MIMICKING ULTRASOUND PHANTOMS PRODUCED WITH A SCANNING MOTION SYSTEM

ULTRASOUND IN MEDICINE AND BIOLOGY, 37(5), 827–833.

By: R. Gessner n, R. Kothadia n, S. Feingold n & P. Dayton n

author keywords: Phantom; Microbubble; Contrast; 3-D imaging; Vessel; Vessel network; Vessel architecture
MeSH headings : Artifacts; Biomimetic Materials; Contrast Media; Humans; Image Enhancement; Imaging, Three-Dimensional; Microvessels / diagnostic imaging; Motion; Sensitivity and Specificity; Ultrasonography / instrumentation; Ultrasonography / methods
TL;DR: A method to create predefined structures with <10 μm precision using a three-axis motion system is presented, which enables one to precisely simulate very slow blood flow and respiration artifacts, and to measure imaging resolution. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 conference paper

Improving biocompatibily of laser micromachined silicon wafer by surface coating with poly(ethylene glycol) diacrylate and diamond-like carbon for biomedical devices

Proceedings of the ASME International Manufacturing Science and Engineering Conference 2010, vol 2, 273–280.

By: P. Wongwiwat n, R. Narayan* & Y. Lee n 

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

DECAFLUOROBUTANE AS A PHASE-CHANGE CONTRAST AGENT FOR LOW-ENERGY EXTRAVASCULAR ULTRASONIC IMAGING

ULTRASOUND IN MEDICINE AND BIOLOGY, 37(9), 1518–1530.

By: P. Sheeran n, V. Wong *, S. Luois*, R. McFarland*, W. Ross *, S. Feingold n, T. Matsunaga*, P. Dayton n

author keywords: Ultrasound; Microbubble; Contrast agent; Perfluorocarbon; Acoustic droplet vaporization
MeSH headings : Acoustics; Contrast Media / chemistry; Fluorocarbons / chemistry; Microbubbles; Microvessels; Nanoparticles / chemistry; Transducers; Ultrasonography / methods
TL;DR: It is shown that decafluorobutane, which is normally a gas at room temperature, can be incorporated into metastable liquid sub-micron droplets with appropriate encapsulation methods and are activatable with substantially less energy than other favored PCCA compounds. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Single-cell analysis of phosphoinositide 3-kinase and phosphatase and tensin homolog activation

Faraday Discussions, 149, 187–200.

By: D. Jiang, C. Sims & N. Allbritton

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Multiphoton microscopy of transdermal quantum dot delivery using two photon polymerization-fabricated polymer microneedles

FARADAY DISCUSSIONS, 149, 171–185.

By: S. Gittard n, P. Miller n, R. Boehm n, A. Ovsianikov *, B. Chichkov *, J. Heiser*, J. Gordon*, N. Monteiro-Riviere n , R. Narayan n

MeSH headings : Administration, Cutaneous; Animals; Drug Delivery Systems / instrumentation; Female; Humans; Infant, Newborn; Keratinocytes / chemistry; Microinjections / methods; Microscopy, Fluorescence; Needles; Polymers / chemistry; Quantum Dots; Skin / chemistry; Skin / cytology; Swine
TL;DR: In this study, microneedle devices for transdermal drug delivery were fabricated by means of two-photon polymerization of an acrylate-based polymer to examine proliferation of cells on this polymer using neonatal human epidermal keratinocytes and human dermal fibroblasts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Dietary Calcium Restriction Affects Mesenchymal Stem Cell Activity and Bone Development in Neonatal Pigs

JOURNAL OF NUTRITION, 141(3), 373–379.

By: A. Mahajan n, L. Alexander n, B. Seabolt n, D. Catrambone*, J. McClung*, J. Odle n , T. Pfeiler n, E. Loboa n, C. Stahl n

MeSH headings : 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / genetics; 25-Hydroxyvitamin D3 1-alpha-Hydroxylase / metabolism; Animals; Animals, Newborn; Bone Density; Bone Development; Bone and Bones / chemistry; Calcitriol / blood; Calcium / blood; Calcium / deficiency; Calcium, Dietary / administration & dosage; Cell Differentiation; Cell Proliferation; Cells, Cultured; Female; Gene Expression Regulation; Male; Mechanical Phenomena; Mesenchymal Stem Cells / cytology; Mesenchymal Stem Cells / metabolism; Nutritional Status; Parathyroid Hormone / blood; RNA, Messenger / metabolism; Receptors, Calcium-Sensing / genetics; Receptors, Calcium-Sensing / metabolism; Sus scrofa
TL;DR: The results indicate that neonatal Ca nutrition is crucial for bone integrity and suggest that early-life Ca restriction may have long-term effects on bone integrity via programming of MSC. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Continuous analysis of dye-loaded, single cells on a microfluidic chip

Lab on a Chip, 11(7), 1333–1341.

By: K. Phillips, H. Lai, E. Johnson, C. Sims & N. Allbritton

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Recombinant Human Interleukin-11 Treatment Enhances Collateral Vessel Growth After Femoral Artery Ligation

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 31(2), 306–312.

By: J. Aitsebaomo n, S. Srivastava  n, H. Zhang  n, S. Jha  n, Z. Wang  n, S. Winnik  n, A. Veleva n, X. Pi  n ...

author keywords: blood flow; ischemia; peripheral arterial disease; peripheral vasculature; reperfusion
MeSH headings : Animals; Antigens, CD34 / metabolism; Cell Movement / drug effects; Cell Movement / physiology; Cells, Cultured; Disease Models, Animal; Femoral Artery / cytology; Femoral Artery / drug effects; Femoral Artery / growth & development; Hindlimb / blood supply; Humans; Interleukin-11 / pharmacology; Ischemia / metabolism; Ischemia / pathology; Leukocytes, Mononuclear / cytology; Leukocytes, Mononuclear / drug effects; Leukocytes, Mononuclear / metabolism; Ligation; Mice; Neovascularization, Physiologic / physiology; Recombinant Proteins / pharmacology; STAT3 Transcription Factor / metabolism; Vascular Endothelial Growth Factor Receptor-2 / metabolism
TL;DR: Findings show that rhIL-11 promotes in vivo mobilization of CD34+/VEGFR2+ mononuclear cells, enhances collateral vessel growth, and increases recovery of perfusion after femoral artery ligation, and has a promising role for development as an adjunctive treatment of patients with peripheral vascular disease. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Full-Spectrum CT Reconstruction Using a Weighted Least Squares Algorithm With an Energy-Axis Penalty

IEEE TRANSACTIONS ON MEDICAL IMAGING, 30(2), 173–183.

By: B. Gonzales n & D. Lalush n

author keywords: Attenuation curve; cadmium zinc telluride (CZT) detectors; penalized weighted least squares (PWLS); X-ray computed tomography
MeSH headings : Algorithms; Cadmium; Image Processing, Computer-Assisted / methods; Least-Squares Analysis; Phantoms, Imaging; Reproducibility of Results; Tellurium; Tomography, X-Ray Computed / instrumentation; Tomography, X-Ray Computed / methods; Zinc
TL;DR: This paper proposes a penalized weighted least squares (PWLS) algorithm for reconstruction of polychromatic energy-differentiated X-ray CT data and a unique experimental setup to take energy- differentiatedX-rayCT data, and concludes that this algorithm is an effective method for reconstructing energy-sensitive CT data. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Efficient In Vivo Selection of a Novel Tumor-Associated Peptide from a Phage Display Library

MOLECULES, 16(1), 900–914.

By: A. Veleva n, D. Nepal*, C. Frederick n, J. Schwab*, P. Lockyer *, H. Yuan *, D. Lalush n, C. Patterson*

author keywords: in vivo phage display; circulating bone marrow derived tumor homing cells; tumor-associated peptides; targeting neovascular growth; positron emission tomography (PET) imaging
MeSH headings : Amino Acid Sequence; Animals; Bacteriophages / genetics; Mice; Neoplasms, Experimental / genetics; Peptides / chemistry; Peptides / genetics; Peptides / isolation & purification
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2011 article

Deposition of antibacterial of poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80/gentamicin sulfate composite coatings by MAPLE

Cristescu, R., Popescu, C., Socol, G., Visan, A., Mihailescu, I. N., Gittard, S. D., … Chrisey, D. B. (2011, April 1). APPLIED SURFACE SCIENCE, Vol. 257, pp. 5287–5292.

By: R. Cristescu *, C. Popescu*, G. Socol *, A. Visan *, I. Mihailescu*, S. Gittard n, P. Miller n, T. Martin n ...

author keywords: Poly(1,3-bis-(p-carboxyphenoxy propane)-co-(sebacic anhydride)) 20:80; Gentamicin; Matrix assisted pulsed laser evaporation; Drug delivery
TL;DR: The studies indicate that deposition of polymer–drug composite thin films prepared by MAPLE is a suitable technique for performing controlled drug delivery and may be used to fabricate thin films of good morphological quality. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Selection and Separation of Viable Cells Based on a Cell-Lethal Assay

ANALYTICAL CHEMISTRY, 83(1), 278–283.

By: W. Xu  n, A. Herman n, C. Phillips n, J. Pai n, C. Sims n & N. Allbritton n

MeSH headings : Animals; Cell Adhesion; Cell Culture Techniques; Cell Separation / instrumentation; Cell Separation / methods; Cell Survival; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases / metabolism; Feasibility Studies; HeLa Cells; Humans; Mice; NIH 3T3 Cells; Tissue Array Analysis
TL;DR: These microarrays enabling clonal colony segmentation permitted sampling and manipulation of the colonies at very early times and at small cell numbers to reduce reagent, time, and manpower requirements. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2011 journal article

Three-dimensional laser micro- and nano-structuring of acrylated poly(ethylene glycol) materials and evaluation of their cytoxicity for tissue engineering applications

ACTA BIOMATERIALIA, 7(3), 967–974.

By: A. Ovsianikov *, M. Malinauskas *, S. Schlie*, B. Chichkov *, S. Gittard n, R. Narayan n, M. Loebler, K. Sternberg*, K. Schmitz*, A. Haverich *

author keywords: Scaffolds; Polymer; PEG; Tissue engineering; Cytotoxicity
MeSH headings : Acrylates / chemistry; Cell Survival; Lasers; Microscopy, Confocal; Nanotechnology; Polyethylene Glycols / chemistry; Polyethylene Glycols / pharmacology; Spectroscopy, Near-Infrared; Tissue Engineering
TL;DR: The results of this work suggest that 2PP may be used to polymerize poly(ethylene glycol)-based materials into three-dimensional structures with well-defined geometries that mimic the physical and biological properties of native cell environments. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

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