Works Published in 2014

search works

Displaying works 101 - 120 of 140 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2014 journal article

High-aspect-ratio nanoporous membranes made by reactive ion etching and e-beam and interference lithography

MICROSYSTEM TECHNOLOGIES-MICRO-AND NANOSYSTEMS-INFORMATION STORAGE AND PROCESSING SYSTEMS, 20(10-11), 1797–1802.

Source: Web Of Science
Added: August 6, 2018

2014 journal article

Folding graft copolymer with pendant drug segments for co-delivery of anticancer drugs

BIOMATERIALS, 35(25), 7194–7203.

author keywords: Graft copolymer; Micelle; Combination therapy; Bio-inspired; Ring open polymerization; Nanomedicine
MeSH headings : Animals; Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Camptothecin / chemistry; Camptothecin / pharmacology; Cell Line, Tumor; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Endocytosis / drug effects; Female; Humans; Hydrophobic and Hydrophilic Interactions; Mice; Mice, Nude; Micelles; Nanostructures / chemistry; Polyethylene Glycols / chemistry; Polymers / chemistry; Xenograft Model Antitumor Assays
TL;DR: In vivo study validated that the nanocarriers exhibited strong accumulation in tumor sites and showed a prominent anticancer activity against the lung cancer xenograft mice model compared with free drugs. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Enzyme-responsive nanomaterials for controlled drug delivery

NANOSCALE, 6(21), 12273–12286.

By: Q. Hu n, P. Katti* & Z. Gu n

MeSH headings : Animals; Apoptosis; Biotechnology; Drug Delivery Systems; Enzymes / chemistry; Humans; Inorganic Chemicals / chemistry; Liposomes / chemistry; Metal Nanoparticles / chemistry; Mice; Nanostructures / chemistry; Nanotechnology; Oxidoreductases / chemistry; Peptide Hydrolases / chemistry; Phospholipases / chemistry
TL;DR: This review describes enzymes such as proteases, phospholipases and oxidoreductases that serve as delivery triggers and explores recently developed enzyme-responsive nanomaterials with versatile applications for extracellular and intracellular drug delivery. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Cocoon-Like Self-Degradable DNA Nanoclew for Anticancer Drug Delivery

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 136(42), 14722–14725.

By: W. Sun n, T. Jiang n, Y. Lu n, M. Reiff n, R. Mo n & Z. Gu n

MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; DNA / chemistry; DNA / metabolism; Deoxyribonucleases / metabolism; Doxorubicin / chemistry; Doxorubicin / pharmacology; Drug Carriers / chemistry; Drug Carriers / metabolism; Drug Liberation; Humans; MCF-7 Cells; Models, Molecular; Molecular Conformation; Nanoparticles / chemistry
TL;DR: In an acidic environment, the activity of DNase I was activated through the acid-triggered shedding of the polymeric shell of the NCa, resulting in the cocoon-like self-degradation of the NCl and promoting the release of DOX for enhanced therapeutic efficacy. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 article

Biobotic Insect Swarm based Sensor Networks for Search and Rescue

SIGNAL PROCESSING, SENSOR/INFORMATION FUSION, AND TARGET RECOGNITION XXIII, Vol. 9091.

author keywords: Insect biobots; Seach and rescue; Neural engineering; Swarm robotics; Topological mapping; Sensor networks
TL;DR: This work has benefitted from recent developments in neural engineering and neuromuscular stimulation research to fuse the locomotory advantages of insects with the latest developments in wireless networking technologies to enable biobotic insect agents to function as search-and-rescue agents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

An Immature Retroviral RNA Genome Resembles a Kinetically Trapped Intermediate State

JOURNAL OF VIROLOGY, 88(11), 6061–6068.

By: J. Grohman*, R. Gorelick*, S. Kottegoda*, N. Allbritton n, A. Rein* & K. Weeks*

MeSH headings : Acylation; DNA Primers / genetics; Dimerization; Electrophoresis, Capillary; Genome, Viral / genetics; Models, Molecular; Moloney murine leukemia virus / genetics; RNA, Viral / genetics; Virion / genetics; Virion / growth & development
TL;DR: It is found that the genomic RNA is packaged in a high-energy state, suggesting that interactions within the virion hold or capture the RNA before it reaches its most stable state. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Ultrasound-Triggered Regulation of Blood Glucose Levels Using Injectable Nano-Network

ADVANCED HEALTHCARE MATERIALS, 3(6), 811–816.

By: J. Di n, J. Price n, X. Gu*, X. Jiang n, Y. Jing n & Z. Gu n

MeSH headings : Alginates / chemistry; Animals; Blood Glucose / analysis; Chitosan / chemistry; Diabetes Mellitus, Experimental / metabolism; Diabetes Mellitus, Experimental / pathology; Diabetes Mellitus, Experimental / therapy; Drug Carriers / chemistry; Glucuronic Acid / chemistry; Hexuronic Acids / chemistry; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Insulin / administration & dosage; Insulin / chemistry; Lactic Acid / chemistry; Male; Mice; Mice, Inbred C57BL; Nanostructures / chemistry; Polyglycolic Acid / chemistry; Polylactic Acid-Polyglycolic Acid Copolymer; Ultrasonic Therapy
TL;DR: The integration of an injectable insulin-encapsulated nano-network with a focused ultrasound system (FUS) can remotely regulate insulin release both in vitro and in vivo. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Transient Antibody-Mucin Interactions Produce a Dynamic Molecular Shield against Viral Invasion

BIOPHYSICAL JOURNAL, 106(9), 2028–2036.

MeSH headings : Antibodies, Neutralizing / immunology; Antibodies, Neutralizing / metabolism; Antibodies, Viral / metabolism; Antibody Specificity; Cervix Uteri / virology; Female; HIV-1 / physiology; Humans; Immunoglobulin G / immunology; Kinetics; Mucins / metabolism; Mucus / virology; Protein Binding; Vagina / virology
TL;DR: The model developed here is adaptable to other pathogens, mucosal barriers, and geometries, as well as kinetic and diffusional effects, providing a tool for hypothesis testing and producing quantitative insights into the dynamics of immune-mediated protection. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Small Sample Sorting of Primary Adherent Cells by Automated Micropallet Imaging and Release

CYTOMETRY PART A, 85A(7), 642–649.

By: P. Shah n, S. Herrera-Loeza*, C. Sims*, J. Yeh* & N. Allbritton n

author keywords: image cytometry; xenografts; cell sorting; micropallet arrays
MeSH headings : Animals; Antigens, Neoplasm / analysis; Cell Adhesion Molecules / analysis; Colorectal Neoplasms / pathology; Electronic Data Processing; Epithelial Cell Adhesion Molecule; Flow Cytometry / methods; Heterografts / cytology; Humans; Image Processing, Computer-Assisted; Mice; Mice, Nude; Pancreatic Neoplasms / pathology; Staining and Labeling; Tumor Cells, Cultured
TL;DR: A platform for imaging cytometry integrated with micropallet array technology is developed to perform automated cell sorting on very small samples obtained from PDX models of pancreatic and colorectal cancer using antibody staining of EpCAM (CD326) as a selection criteria, demonstrating the ability to automate and efficiently separate samples with very low number of cells. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Novel, silver-ion-releasing nanofibrous scaffolds exhibit excellent antibacterial efficacy without the use of silver nanoparticles

ACTA BIOMATERIALIA, 10(5), 2096–2104.

By: M. Mohiti-Asli n, B. Pourdeyhimi n & E. Loboa n

author keywords: Antimicrobial; Silver; Biocompatibility; Wound dressing; Nanofibers
MeSH headings : Adult; Anti-Bacterial Agents / pharmacology; Biocompatible Materials / pharmacology; Cell Proliferation / drug effects; Cell Shape / drug effects; Cell Survival / drug effects; Dermis / cytology; Epidermal Cells; Escherichia coli / drug effects; Fibroblasts / cytology; Fibroblasts / drug effects; Fibroblasts / ultrastructure; Humans; Ions; Keratinocytes / cytology; Keratinocytes / drug effects; Keratinocytes / ultrastructure; Lactic Acid / chemistry; Mass Spectrometry; Metal Nanoparticles / chemistry; Microbial Sensitivity Tests; Nanofibers / chemistry; Nanofibers / ultrastructure; Photoelectron Spectroscopy; Polyesters; Polymers / chemistry; Silver / pharmacology; Staphylococcus aureus / drug effects; Tissue Scaffolds / chemistry
TL;DR: This is the first study to show that silver ions can be effectively delivered with nanofibrous scaffolds without the use of silver nanoparticles, and a new silver ion release polymeric coating is presented and evaluated. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Nonsurgical treatment for localized hepatocellular carcinoma

Current Oncology Reports, 16(3).

By: A. Kennedy & B. Sangro

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Microneedle-Based Transdermal Sensor for On-Chip Potentiometric Determination of K+

ADVANCED HEALTHCARE MATERIALS, 3(6), 876–881.

By: P. Miller n, X. Xiao*, I. Brener*, D. Burckel*, R. Narayan n & R. Polsky*

MeSH headings : Biosensing Techniques; Carbon / chemistry; Electrochemical Techniques / instrumentation; Graphite / chemistry; Ion-Selective Electrodes; Ions / chemistry; Microfluidic Analytical Techniques; Porosity; Potassium / analysis
TL;DR: 3D porous carbon and 3D porous graphene electrodes, made via interference lithography, are compared as solid‐state transducers for ISE's and evaluated for electrochemical performance, stability, and selectivity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Measurement of Protein Kinase B Activity in Single Primary Human Pancreatic Cancer Cells

ANALYTICAL CHEMISTRY, 86(9), 4573–4580.

By: A. Proctor*, S. Herrera-Loeza*, Q. Wang*, D. Lawrence*, J. Yeh* & N. Allbritton n

MeSH headings : Adenocarcinoma / enzymology; Adenocarcinoma / pathology; Blotting, Western; Cell Line, Tumor; Humans; Pancreatic Neoplasms / enzymology; Pancreatic Neoplasms / pathology; Proto-Oncogene Proteins c-akt / metabolism
TL;DR: The ability of chemical cytometry to identify important differences in enzymatic behavior between primary cells and tissue-cultured cell lines is demonstrated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Immobilization of lambda exonuclease onto polymer micropillar arrays for the solid-phase digestion of dsDNAs

Analytical Chemistry, 86(9), 4447–4454.

By: N. Oliver-Calixte, F. Uba, K. Battle, K. Weerakoon-Ratnayake & S. Soper

Source: NC State University Libraries
Added: August 6, 2018

2014 journal article

Growth of Zircone on Nanoporous Alumina Using Molecular Layer Deposition

JOM, 66(4), 649–653.

By: R. Hall*, S. George*, Y. Kim*, W. Hwang*, M. Samberg n, N. Monteiro-Riviere n, R. Narayan n

Source: Web Of Science
Added: August 6, 2018

2014 review

Emerging micro-and nanotechnology based synthetic approaches for insulin delivery

[Review of ]. CHEMICAL SOCIETY REVIEWS, 43(10), 3595–3629.

By: R. Mo n, T. Jiang n, J. Di n, W. Tai n & Z. Gu n

MeSH headings : Diabetes Mellitus / drug therapy; Drug Delivery Systems; Equipment Design; Humans; Insulin / administration & dosage; Insulin / therapeutic use; Insulin Infusion Systems; Nanotechnology / instrumentation
TL;DR: This review outlines recent developments in the controlled delivery of insulin, including oral, nasal, pulmonary, transdermal, subcutaneous and closed-loop insulin delivery. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 article

Biological, Electronic, and Functional Thin Films

Narayan, R. (2014, April). JOM, Vol. 66, pp. 588–589.

By: R. Narayan n

Source: Web Of Science
Added: August 6, 2018

2014 journal article

ATP-triggered anticancer drug delivery

NATURE COMMUNICATIONS, 5.

MeSH headings : Adenosine Triphosphate / chemistry; Animals; Antineoplastic Agents / administration & dosage; Antineoplastic Agents / pharmacokinetics; Apoptosis; Cell Line; Cell Line, Tumor; Doxorubicin / administration & dosage; Doxorubicin / pharmacokinetics; Drug Carriers / chemistry; Female; Humans; MCF-7 Cells; Mice; Mice, Nude; Nanoparticles / chemistry; Polymers / chemistry; Xenograft Model Antitumor Assays
TL;DR: Nanocarriers are developed that take advantage of high ATP levels in tumour cells and show that these nanoparticles encapsulating the chemotherapeutic doxorubicin can inhibit tumour growth in mice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Stereolithography in tissue engineering

JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 25(3), 845–856.

MeSH headings : Guided Tissue Regeneration / instrumentation; Imaging, Three-Dimensional / methods; Photography / methods; Prosthesis Design / instrumentation; Prosthesis Design / methods; Tissue Engineering / instrumentation; Tissue Engineering / methods; Tissue Scaffolds
TL;DR: Use of stereolithography for processing trimethylene carbonate, polycaprolactone, and poly(d,l-lactide) poly(propylene fumarate)-based materials is considered, and incorporation of bioceramic fillers for fabrication of biOCeramic scaffolds is reviewed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2014 journal article

Molecule Drugs for Enhanced Therapeutic Efficacy

ADVANCED FUNCTIONAL MATERIALS, 24(16), 2295–2304.

author keywords: drug delivery; combination cancer therapy; site-specific delivery; nanomedicine; apoptosis
TL;DR: With the programmed choreography, Gelipo significantly improves the inhibition of the tumor growth in the MDA‐MB‐231 xenograft tumor animal model. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.