Works Published in 2015
Displaying works 101 - 120 of 164 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2015 journal article
Microfabricated Collector-Generator Electrode Sensor for Measuring Absolute pH and Oxygen Concentrations
ANALYTICAL CHEMISTRY, 87(20), 10556–10564.
MeSH headings : Electrochemical Techniques / instrumentation; Hydrogen-Ion Concentration; Microelectrodes; Oxygen / analysis
TL;DR:
A microfabricated microelectrode array which uses FSCV to detect the absolute levels of oxygen and pH in vitro and a periodic potential step is applied at the generator producing transient local changes in the electrochemical environment.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2015 journal article
Integrin alpha 3 beta 1 binding to fibronectin is dependent on the ninth type III repeat
Journal of Biological Chemistry, 290(42), 25534–25547.
MeSH headings : Amino Acid Sequence; Cell Adhesion; Cell Line; Fibronectins / chemistry; Fibronectins / genetics; Fibronectins / metabolism; Humans; Integrin alpha3beta1 / metabolism; Molecular Sequence Data; Mutation; Protein Binding
TL;DR:
These studies suggest that the presence and spacing of the RGD and synergy sites modulate integrin α3β1 binding to Fn.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
High-Temperature Electromechanical Characterization of AlN Single Crystals
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL, 62(10), 1880–1887.
TL;DR:
High electrical resistivity, temperature independence of electromechanical properties, as well as high thermal resistivity of the elastic, dielectric, and piezoelectric properties, suggest that AlN single crystals are a promising candidate for high-temperature piezOElectric sensing applications.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Electrodeposited Iron as a Biocompatible Material for Microneedle Fabrication
ELECTROANALYSIS, 27(9), 2239–2249.
author keywords: Microneedle; Electroplating; Coating; Iron
TL;DR:
Iron coatings proved to significantly improve the strength of the hollow polymer microneedles and sustained structural integrity up to 7 insertions into porcine skin without bending.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Adult Lung Spheroid Cells Contain Progenitor Cells and Mediate Regeneration in Rodents With Bleomycin-Induced Pulmonary Fibrosis
STEM CELLS TRANSLATIONAL MEDICINE, 4(11), 1265–1274.
author keywords: Adult lung stem cells; Mesenchymal stem cells; Pulmonary fibrosis; Spheroid cell culture
MeSH headings : Adult; Animals; Antibiotics, Antineoplastic / adverse effects; Antibiotics, Antineoplastic / pharmacology; Bleomycin / adverse effects; Bleomycin / pharmacology; Female; Heterografts; Humans; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells / metabolism; Mesenchymal Stem Cells / pathology; Mice; Mice, SCID; Pulmonary Fibrosis / chemically induced; Pulmonary Fibrosis / metabolism; Pulmonary Fibrosis / pathology; Pulmonary Fibrosis / therapy; Regeneration; Spheroids, Cellular / metabolism; Spheroids, Cellular / transplantation
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Separation of peptide fragments of a protein kinase C substrate fused to a beta-hairpin by capillary electrophoresis
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 407(30), 8999–9008.
author keywords: Capillary electrophoresis; beta-Hairpin; Peptide separation; PKC; Protease resistance; Reporter
MeSH headings : Electrophoresis, Capillary / methods; Molecular Structure; Peptide Fragments / chemistry; Peptide Fragments / isolation & purification; Phosphorylation; Protein Kinase C / chemistry
TL;DR:
Capillary-electrophoretic separation conditions for WKpG β-hairpin peptide fused to a protein kinase C (PKC) substrate were developed and could be detected and separated from peptidase-generated fragments produced in a cell lysate.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Pronase E-Based Generation of Fluorescent Peptide Fragments: Tracking Intracellular Peptide Fate in Single Cells
ANALYTICAL CHEMISTRY, 87(15), 7987–7995.
MeSH headings : Amino Acid Sequence; Fluorescence; Intracellular Space / metabolism; Models, Biological; Molecular Sequence Data; Peptide Fragments / biosynthesis; Peptide Fragments / metabolism; Pronase / metabolism; Proteolysis; Single-Cell Analysis / methods; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization
TL;DR:
A rapid and inexpensive methodology to generate fluorescent peptide fragments from a parent sequence with diverse chemical properties, including aliphatic, nonpolar, basic, acidic, and non-native amino acids is described.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Phantom evaluation of stacked-type dual-frequency 1-3 composite transducers: A feasibility study on intracavitary acoustic angiography
ULTRASONICS, 63, 7–15.
author keywords: Dual-frequency transducer; 1-3 composite transducer; Superharmonic imaging; Ultrasound contrast agents; Intracavitary probe
MeSH headings : Acoustics; Angiography / instrumentation; Contrast Media; Equipment Design; Feasibility Studies; Humans; Image Enhancement / methods; Microbubbles; Phantoms, Imaging; Signal-To-Noise Ratio; Transducers; Ultrasonography, Interventional / instrumentation; Ultrasonography, Interventional / methods
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Magnetic Alignment of Microelements Containing Cultured Neuronal Networks for High-Throughput Screening
JOURNAL OF BIOMOLECULAR SCREENING, 20(9), 1091–1100.
author keywords: high-throughput screening; primary neurons; magnetic centering; microfabrication; finite element analysis; microraft arrays
MeSH headings : Animals; Cell Survival; Cells, Cultured; Drug Evaluation, Preclinical; High-Throughput Screening Assays / instrumentation; High-Throughput Screening Assays / methods; Magnetic Phenomena; Nerve Net / cytology; Neurons / drug effects; Neurons / physiology; Rats, Sprague-Dawley
TL;DR:
A magnet array plate is developed, compatible with HTS fluid-handling systems, to center microrafts within wells, finding a centering efficiency of 100%, compared with 4.35% using a flat magnet, and concluding that micRORafts could be centered after settling randomly within the well, overcoming friction.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Extracellular Calcium Modulates Chondrogenic and Osteogenic Differentiation of Human Adipose-Derived Stem Cells: A Novel Approach for Osteochondral Tissue Engineering Using a Single Stem Cell Source
TISSUE ENGINEERING PART A, 21(17-18), 2323–2333.
MeSH headings : Adipose Tissue / cytology; Adult; Calcification, Physiologic / drug effects; Calcium / pharmacology; Calcium Phosphates / pharmacology; Cell Differentiation / drug effects; Cells, Cultured; Chondrogenesis / drug effects; Extracellular Space / chemistry; Gene Expression Regulation / drug effects; Glycosaminoglycans / metabolism; Humans; Immunohistochemistry; Lactic Acid / pharmacology; Osteogenesis / drug effects; Polyesters; Polymers / pharmacology; Stem Cells / cytology; Stem Cells / drug effects; Stem Cells / ultrastructure; Tissue Engineering / methods; Tissue Scaffolds; Young Adult
TL;DR:
This is the first study to report the effects of elevated calcium on chondrogenic differentiation of hASC, and to develop osteochondral nanofibrous scaffolds using a single cell source and controlled calcium release to induce site-specific differentiation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Engineering Synthetic Insulin-Secreting Cells Using Hyaluronic Acid Microgels Integrated with Glucose-Responsive Nanoparticles
CELLULAR AND MOLECULAR BIOENGINEERING, 8(3), 445–454.
author keywords: Insulin delivery; Diabetes; Glucose responsive; Bio-inspired; Hyaluronic acid; Dextran
TL;DR:
In vitro studies demonstrated that the insulin release rate associated with HA microgels was effectively regulated by changes in the glucose concentration, and validated that a single injection of the developed formulation stabilized the blood glucose levels in the normoglycemic state for over 1 week.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 article
Dual-frequency Super Harmonic Imaging Piezoelectric Transducers for Transrectal Ultrasound
HEALTH MONITORING OF STRUCTURAL AND BIOLOGICAL SYSTEMS 2015, Vol. 9438.
author keywords: Dual-frequency transducer; transrectal ultrasound; prostate probe; super-harmonic imaging; contrast imaging; mode coupling
TL;DR:
Two dual-frequency transducers were developed for contrast enhanced super-harmonic ultrasound imaging of prostate cancer with the low frequency ultrasound transducer as a transmitter for contrast agent (microbubble) excitation and the high frequency transducher as a receiver for detection of nonlinear responses from microbubbles.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Power amplification in an isolated muscle-tendon unit is load dependent
JOURNAL OF EXPERIMENTAL BIOLOGY, 218(22), 3700–3709.
author keywords: Muscle-tendon system; Elastic energy; Power amplification; Catch mechanism; Acceleration; Jumping
MeSH headings : Animals; Biomechanical Phenomena; Elasticity; Energy Transfer; Locomotion / physiology; Muscle Contraction; Muscle, Skeletal / physiology; Rana catesbeiana / physiology; Tendons / physiology
TL;DR:
Power amplification in a compliant muscle-tendon unit is maximal for intermediate inertial-gravitational loads and can be enhanced by a trigger and catch mechanism for small loads.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Our Fat Future: Translating Adipose Stem Cell Therapy
STEM CELLS TRANSLATIONAL MEDICINE, 4(9), 974–979.
MeSH headings : Adipocytes / cytology; Adipocytes / physiology; Adipose Tissue / cytology; Adipose Tissue / physiology; Automation, Laboratory / instrumentation; Biomimetic Materials / chemistry; Biosensing Techniques / instrumentation; Cell Differentiation; Cell- and Tissue-Based Therapy / methods; Clinical Trials as Topic; Humans; Stem Cell Transplantation / methods; Stem Cells / cytology; Stem Cells / physiology; Translational Research, Biomedical / legislation & jurisprudence; Translational Research, Biomedical / trends; United States; United States Food and Drug Administration / legislation & jurisprudence; Workforce
TL;DR:
The progress and challenges of bringing adipose stem cell therapy into mainstream clinical use are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Optimizing Wnt-3a and R-spondin1 concentrations for stem cell renewal and differentiation in intestinal organoids using a gradient-forming microdevice
RSC ADVANCES, 5(91), 74881–74891.
TL;DR:
The gradient culture system enabled efficient determination of the minimal growth factor concentrations needed to produce a physiologically-relevant colonoid phenotype, and lower factor concentrations yielded the added benefit of a more morphologically appropriate colonoid possessing columnar cells surrounding a central lumen with active crypt-like bud formation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
In vitro biomechanical evaluation of internal fixation techniques on the canine lumbosacral junction
PeerJ, 3.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Electrophoretic transport of single DNA nucleotides through nanoslits: A molecular dynamics simulation study
Journal of Physical Chemistry. B, Condensed Matter, Materials, Surfaces, Interfaces & Biophysical, 119(35), 11443–11458.
Source: NC State University Libraries
Added: August 6, 2018
2015 journal article
Translating textiles to tissue engineering: Creation and evaluation of microporous, biocompatible, degradable scaffolds using industry relevant manufacturing approaches and human adipose derived stem cells
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 103(5), 1050–1058.
author keywords: porous scaffolds; bone tissue engineering; Islands-In-The-Sea; human adipose-derived stem cells
MeSH headings : Absorbable Implants; Adipose Tissue / cytology; Adipose Tissue / metabolism; Cell Differentiation; Cells, Cultured; Humans; Materials Testing; Osteogenesis; Porosity; Stem Cells / cytology; Stem Cells / metabolism; Textiles; Tissue Engineering; Tissue Scaffolds / chemistry
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Polypyrrole-Based Implantable Electroactive Pump for Controlled Drug Microinjection
ACS APPLIED MATERIALS & INTERFACES, 7(27), 14563–14568.
author keywords: polypyrrole; electroactuator; implantable; controlled drug delivery; diabetes
MeSH headings : Electric Conductivity; Electrodes; Equipment Design; Equipment Failure Analysis; Infusion Pumps, Implantable; Micro-Electrical-Mechanical Systems / instrumentation; Microfluidics / instrumentation; Microinjections / instrumentation; Polymers / chemistry; Pyrroles / chemistry
TL;DR:
This work develops a flexible electroactive pump based on a biocompatible polypyrrole composite film that comprises a poly pyrrole matrix and a macromolecular dopant of polycaprolactone-block-polytetrahydrofuran- block-polycaprolACTone to improve the quality of life of diabetics.
(via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018
2015 journal article
Novel genipin-collagen immobilization of polylactic acid (PLA) fibers for use as tissue engineering scaffolds
JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, 103(6), 1188–1197.
author keywords: collagen immobilization; genipin; scaffold; functionalization; surface modification; polylactic acid (PLA) fibers
MeSH headings : Cells, Cultured; Fibroblasts / cytology; Fibroblasts / metabolism; Humans; Iridoids / chemistry; Lactic Acid / chemistry; Materials Testing; Polyesters; Polymers / chemistry; Tissue Engineering; Tissue Scaffolds / chemistry
TL;DR:
The collagen was immobilized on the surface of functionalized PLA via a novel natural cross-linking moleculegenipin which resulted in improved cell proliferation of human dermal fibroblasts as compared to the PLA surface coated with collagen without genipin.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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