Works Published in 2015

search works

Displaying works 121 - 140 of 164 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 review

Naturally derived and synthetic scaffolds for skeletal muscle reconstruction

[Review of ]. ADVANCED DRUG DELIVERY REVIEWS, 84, 208–221.

By: M. Wolf*, C. Dearth*, S. Sonnenberg n, E. Loboa n & S. Badylak*

author keywords: Extracellular matrix (ECM); Electrospinning; Hybrid materials; Hydrogel; Mesh; Volumetric muscle loss (VML)
MeSH headings : Biocompatible Materials / administration & dosage; Humans; Muscle, Skeletal / physiology; Polymers / administration & dosage; Regeneration / physiology; Tissue Engineering / methods; Tissue Scaffolds
TL;DR: Advances in scaffolds using muscle tissue engineering are reviewed and next generation naturally derived/synthetic "hybrid materials" would combine the advantageous properties of these materials to create an optimal platform for cell/drug delivery and possess inherent bioactive properties. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Cavitation Enhancing Nanodroplets Mediate Efficient DNA Fragmentation in a Bench Top Ultrasonic Water Bath

PLOS ONE, 10(7).

By: S. Kasoji n, S. Pattenden*, E. Malc*, C. Jayakody*, J. Tsuruta n, P. Mieczkowski*, W. Janzen*, P. Dayton n

MeSH headings : DNA Fragmentation / radiation effects; DNA, Fungal; Microbubbles; Sonication / instrumentation; Sonication / methods
TL;DR: A perfluorocarbon nanodroplet formulation is shown to be an effective cavitation enhancement agent, enabling rapid and consistent fragmentation of genomic DNA in a standard ultrasonic water bath, and enables widespread access to fast bench-top genomic DNA fragmentation. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Analysis of sphingosine kinase activity in single natural killer cells from peripheral blood

INTEGRATIVE BIOLOGY, 7(4), 392–401.

MeSH headings : Cells, Cultured; Enzyme Activation; Humans; Killer Cells, Natural / enzymology; Phosphotransferases (Alcohol Group Acceptor) / blood; Phosphotransferases (Alcohol Group Acceptor) / chemistry
TL;DR: In contrast to the SK activity, S1PP activity was homogeneous across the peripheral blood NK cells, suggesting a bias in the SK pathway towards proliferation and migration, activities supported by S1P. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Tendon mechanobiology: Current knowledge and future research opportunities

Journal of Orthopaedic Research, 33(6), 813–822.

By: M. Lavagnino, M. Wall, D. Little, A. Banes, F. Guilak & S. Arnoczky

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Study on the damage mechanism of articular cartilage based on the fluid-solid coupled particle model

Advances in Mechanical Engineering, 7(4).

By: J. Hong, T. Evans & P. Mente

Source: NC State University Libraries
Added: August 6, 2018

2015 journal article

Polyglycolic acid microneedles modified with inkjet-deposited antifungal coatings

BIOINTERPHASES, 10(1).

By: R. Boehm n, J. Daniels*, S. Stafslien*, A. Nasir*, J. Lefebvre* & R. Narayan n

MeSH headings : Antifungal Agents / pharmacology; Bacteria / drug effects; Candida albicans / drug effects; Drug Carriers; Microbial Sensitivity Tests; Polyglycolic Acid; Surface Properties; Technology, Pharmaceutical / methods
TL;DR: Piezoelectric inkjet printing may be useful for loading transdermal drug delivery devices such as polyglycolic acid microneedles with antifungal pharmacologic agents and other pharmacologicagents with poor solubility in aqueous solutions. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Optimization of multi-pulse sequences for nonlinear contrast agent imaging using a cMUT array

PHYSICS IN MEDICINE AND BIOLOGY, 60(8), 3111–3127.

By: A. Novell n, C. Arena n, S. Kasoji n & P. Dayton n

author keywords: bias voltage; chirp; cMUT; contrast agent; microbubbles; multi-pulse sequence; nonlinearity
MeSH headings : Diagnostic Imaging; Electric Capacitance; Humans; Image Enhancement / instrumentation; Image Enhancement / methods; Image Processing, Computer-Assisted / methods; Micro-Electrical-Mechanical Systems / instrumentation; Microbubbles; Phantoms, Imaging; Transducers; Ultrasonography / instrumentation
TL;DR: This study proposes to optimize contrast agent detection by combining the BVM sequence with PI and/or chirp reversal (CR) and results in a significant increase of the contrast-to-noise ratio. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

ON THE RELATIONSHIP BETWEEN MICROBUBBLE FRAGMENTATION, DEFLATION AND BROADBAND SUPERHARMONIC SIGNAL PRODUCTION

ULTRASOUND IN MEDICINE AND BIOLOGY, 41(6), 1711–1725.

By: B. Lindsey, J. Rojas* & P. Dayton*

author keywords: Contrast agent; Microbubble; Harmonic; Superharmonic; Cavitation; Acoustic angiography; Dual frequency
MeSH headings : Acoustics; Angiography / methods; Animals; Contrast Media / chemistry; Kidney / blood supply; Kidney / diagnostic imaging; Microbubbles; Rats; Rats, Inbred F344; Signal Processing, Computer-Assisted; Signal-To-Noise Ratio; Ultrasonography
TL;DR: Although the existence of superharmonic signals when bubbles shrink has the potential to prolong the imaging efficacy of microbubbles, parameters such as frame rate and peak pressure must be balanced with expected re-perfusion rate to maintain adequate contrast during in vivo imaging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Individual limb mechanical analysis of gait following stroke

JOURNAL OF BIOMECHANICS, 48(6), 984–989.

author keywords: Stroke; Hemiplegia; Rehabilitation; Gait; Mechanics
MeSH headings : Aged; Chronic Disease; Exercise Test; Extremities / physiopathology; Female; Gait / physiology; Humans; Male; Middle Aged; Stroke / physiopathology; Walking / physiology
TL;DR: Comparison of individual limb mechanical gait asymmetries during the step-to-step transitions, single-support and over a complete stride between two groups of individuals following stroke stratified by gait speed suggests that limb power output may be dominated by vertical components, which are required for upright support. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Effects of Locomotion Mode Recognition Errors on Volitional Control of Powered Above-Knee Prostheses

IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING, 23(1), 64–72.

By: F. Zhang n, M. Liu n & H. Huang n

Contributors: F. Zhang n, M. Liu n & H. Huang n

author keywords: Gait stability; locomotion mode recognition; powered above-knee prosthesis; volitional control
MeSH headings : Adult; Algorithms; Female; Gait / physiology; Humans; Knee Prosthesis; Locomotion / physiology; Male; Postural Balance / physiology; Prosthesis Design; Reproducibility of Results; Volition
TL;DR: “critical errors” were defined and suggested as a new index to evaluate locomotion mode recognition algorithms for artificial legs to aid the future design of volitionally-controlled powered prosthetic legs that are reliable and safe for practice. (via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2015 journal article

A dual wavelength-activatable gold nanorod complex for synergistic cancer treatment

NANOSCALE, 7(28), 12096–12103.

MeSH headings : Antineoplastic Agents / chemistry; Antineoplastic Agents / pharmacology; Drug Screening Assays, Antitumor; Gold / chemistry; Gold / pharmacology; HeLa Cells; Humans; Infrared Rays; Nanotubes / chemistry; Neoplasms / drug therapy; Photochemotherapy
TL;DR: This multifunctional AuNR-based system represents a novel theranostic strategy for spatiotemporal delivery of anticancer therapeutics and demonstrates enhanced anticancer efficacy through the synergistic combination of promoted drug release upon ultraviolet (UV) light irradiation and photothermal therapy upon infrared (IR) irradiation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Microneedle-array patches loaded with hypoxia-sensitive vesicles provide fast glucose-responsive insulin delivery

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 112(27), 8260–8265.

author keywords: diabetes; drug delivery; glucose-responsive; hypoxia-sensitive; microneedle
MeSH headings : Animals; Blood Glucose / analysis; Diabetes Mellitus, Experimental / blood; Diabetes Mellitus, Experimental / drug therapy; Diabetes Mellitus, Type 1 / blood; Diabetes Mellitus, Type 1 / drug therapy; Drug Delivery Systems / instrumentation; Drug Delivery Systems / methods; Glucose / metabolism; Glucose Oxidase / metabolism; Humans; Hyaluronic Acid / chemistry; Hyaluronic Acid / metabolism; Hypoglycemic Agents / administration & dosage; Hypoglycemic Agents / chemistry; Hypoxia / metabolism; Insulin / administration & dosage; Insulin / chemistry; Insulin / metabolism; Male; Mice, Inbred C57BL; Microscopy, Electron, Transmission; Molecular Structure; Oxidation-Reduction; Reproducibility of Results
TL;DR: The “smart insulin patch” with a new enzyme-based glucose-responsive mechanism can regulate the blood glucose of type 1 diabetic mice to achieve normal levels, with faster responsiveness compared with the commonly used pH-sensitive formulations, and can avoid the risk of hypoglycemia. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

MR-based attenuation correction for PET/MRI neurological studies with continuous-valued attenuation coefficients for bone through a conversion from R2*to CT-Hounsfield units

NEUROIMAGE, 112, 160–168.

MeSH headings : Adipose Tissue / anatomy & histology; Aged; Air; Algorithms; Aniline Compounds; Bone and Bones / anatomy & histology; Bone and Bones / diagnostic imaging; Brain / anatomy & histology; Brain / diagnostic imaging; Ethylene Glycols; Female; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging / methods; Magnetic Resonance Imaging / statistics & numerical data; Male; Middle Aged; Neuroimaging / statistics & numerical data; Positron-Emission Tomography / methods; Positron-Emission Tomography / statistics & numerical data; Radiopharmaceuticals; Skull / anatomy & histology; Skull / diagnostic imaging
TL;DR: The proposed CAR-RiDR method closely approaches (<3% error) the gold standard CT-scaled method in PET reconstruction accuracy and provides a low whole-brain mean absolute percent-error in PET reconstructions across subjects. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 review

Engineering DNA scaffolds for delivery of anticancer therapeutics

[Review of ]. BIOMATERIALS SCIENCE, 3(7), 1018–1024.

By: W. Sun n & Z. Gu n

MeSH headings : DNA / chemistry; Drug Carriers / chemistry; Drug Delivery Systems / methods; Engineering; Humans; Nanoparticles / administration & dosage; Nanoparticles / chemistry; Nanoparticles / therapeutic use; Nanostructures / chemistry; Nanostructures / therapeutic use; Nanotechnology / methods; Neoplasms / chemistry; Neoplasms / drug therapy; Nucleic Acids / chemistry
TL;DR: In this mini-review, current advances in utilizing DNA scaffolds as drug carriers for cancer treatment were summarized and future challenges were also discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Accelerating the Translation of Nanomaterials in Biomedicine

ACS NANO, 9(7), 6644–6654.

MeSH headings : Nanomedicine / methods; Nanomedicine / trends; Translational Research, Biomedical
TL;DR: The current status and future potential of promising nanomaterials and their translation from the laboratory to the clinic are discussed, by highlighting a handful of successful examples. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Towards characterizing the pressure profiles of medical compression hosiery: an investigation of current measurement devices and techniques

JOURNAL OF THE TEXTILE INSTITUTE, 106(7), 757–767.

author keywords: body measurement; compression garments; medical textiles; interface pressure; measurement and verification
TL;DR: The construction of these compression-measuring devices and the sensing involved are explored in order to highlight the potential causes of discrepancies between point pressure measurements and those predicted from the Tension–Elongation profiles. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2015 review

Therapeutic gas delivery via microbubbles and liposomes

[Review of ]. JOURNAL OF CONTROLLED RELEASE, 209, 139–149.

author keywords: Microbubble; Liposome; Oxygen; Nitric oxide; Xenon; Ultrasound
MeSH headings : Animals; Humans; Liposomes; Microbubbles; Nitric Oxide / administration & dosage; Nitric Oxide / therapeutic use; Oxygen / administration & dosage; Oxygen / therapeutic use; Xenon / administration & dosage; Xenon / therapeutic use
TL;DR: A review provides a summary of recent advances in therapeutic gas delivery using microbubbles and liposomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

Reducing the energy cost of human walking using an unpowered exoskeleton

NATURE, 522(7555), 212-+.

By: S. Collins*, M. Wiggin n & G. Sawicki n

MeSH headings : Ankle / physiology; Artificial Limbs; Bionics / instrumentation; Bionics / methods; Energy Metabolism; Female; Foot / physiology; Humans; Leg / physiology; Male; Muscle, Skeletal / physiology; Walking / physiology; Young Adult
TL;DR: This work built a lightweight elastic device that acts in parallel with the user's calf muscles, off-loading muscle force and thereby reducing the metabolic energy consumed in contractions, and shows that the metabolic rate of human walking can be reduced by an unpowered ankle exoskeleton. (via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2015 review

Recent advances in nanotechnology for diabetes treatment

[Review of ]. WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 7(4), 548–564.

MeSH headings : Diabetes Mellitus / therapy; Electrochemical Techniques; Glucose / analysis; Humans; Insulin / administration & dosage; Insulin Infusion Systems; Nanotechnology / trends
TL;DR: Recent progress in the field of diabetes research at its interface with nanotechnology is examined, including glucose sensors with nanoscale components including metal nanoparticles and carbon nanostructures and 'Closing the loop' between BGL measurements and insulin administration by removing the requirement of patient action is discussed. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2015 journal article

QUANTIFICATION OF MICROVASCULAR TORTUOSITY DURING TUMOR EVOLUTION USING ACOUSTIC ANGIOGRAPHY

ULTRASOUND IN MEDICINE AND BIOLOGY, 41(7), 1896–1904.

author keywords: Tortuosity; Contrast agent; Microbubble; Ultrasound; Acoustic angiography; Microvasculature; Angiogenesis; Superharmonic imaging
MeSH headings : Algorithms; Angiography / methods; Animals; Breast Neoplasms / blood supply; Breast Neoplasms / complications; Breast Neoplasms / pathology; Elasticity Imaging Techniques / methods; Female; Humans; Image Enhancement / methods; Image Interpretation, Computer-Assisted / methods; Male; Mice; Microvessels / diagnostic imaging; Neovascularization, Pathologic / complications; Neovascularization, Pathologic / pathology; Reproducibility of Results; Sensitivity and Specificity
TL;DR: Quantitative morphologic analysis of tumor vessels revealed significantly increased vascular tortuosity abnormalities associated with tumor growth, with the distance metric elevated approximately 14% and the sum of angles metric increased 60% in tumor vessels versus controls. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.