Works Published in 2014
Displaying works 1 - 20 of 140 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 conference paper
The implementation of acoustic angiography for microvascular and angiogenesis imaging
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society. Presented at the 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).
Event: 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)
TL;DR:
Because microbubbles are strictly an intravascular agent, this approach enables visualization of microvascular morphology with unique clarity, providing insight into angiogenesis associated with tumor development.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: September 3, 2023
2014 article proceedings
Pro-angiogenic factors enhance pericyte function during angiogenesis
Presented at the 2014 40th Annual Northeast Bioengineering Conference (NEBEC).
Event: 2014 40th Annual Northeast Bioengineering Conference (NEBEC)
TL;DR:
The results demonstrate the importance of temporal control over signaling in promoting vascular growth and vessel maturation and could be useful to promote healing after acute wounds and in chronic conditions such as diabetic ulcers and peripheral artery disease.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: July 9, 2023
2014 conference paper
Odor assessment of automobile cabin air by machine olfaction
IEEE SENSORS 2014 Proceedings. Presented at the 2014 IEEE Sensors.
Event: 2014 IEEE Sensors
TL;DR:
A machine olfaction approach to assess odors inside automobiles for the purpose of enhancing or replacing the human panel by evaluating the correlation between the system performance and a trained human panel supports the feasibility of replacing human panel assessments by a machine Olfaction system.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: July 2, 2023
2014 conference paper
Durability of a Device Designed for Cardiac Assist and Support in a Failing Heart
Adkins, A. N., Brown, K., Hord, E., Bolch, C., & Criscione, J. C. (2014, October). Poster presented at the Biomedical Engineering Society (BMES) Annual Conference, San Antonio, Texas.
Event: Biomedical Engineering Society (BMES) Annual Conference at San Antonio, Texas
Source: NC State University Libraries
Added: June 17, 2022
2014 journal article
Reduced tissue-level stiffness and mineralization in osteoporotic cancellous bone
Calcified Tissue International, 95(2), 125–131.
Source: ORCID
Added: April 4, 2022
2014 journal article
Drug Delivery: Ultrasound-Triggered Regulation of Blood Glucose Levels Using Injectable Nano-Network (Adv. Healthcare Mater. 6/2014)
Advanced Healthcare Materials, 3(6), 789–789.
Source: Crossref
Added: April 3, 2022
2014 journal article
Drug Delivery: Gel-Liposome-Mediated Co-Delivery of Anticancer Membrane-Associated Proteins and Small-Molecule Drugs for Enhanced Therapeutic Efficacy (Adv. Funct. Mater. 16/2014)
Advanced Functional Materials, 24(16), 2258–2258.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: April 3, 2022
2014 journal article
Lipid-Like Nanomaterials for Simultaneous Gene Expression and Silencing In Vivo
Advanced Healthcare Materials, 3(9), 1392–1397.
MeSH headings : Animals; Gene Expression; Gene Silencing; HeLa Cells; Humans; Lipids / chemistry; Lipids / pharmacokinetics; Mice; Mice, Inbred C57BL; Nanostructures / chemistry; RNA, Small Interfering / genetics; RNA, Small Interfering / metabolism; Transfection / methods; Triazines / chemistry
TL;DR:
Self-assembled nanoparticles are shown to induce simultaneous gene expression and silencing both in vitro and in vivo, and to simultaneously regulate expression of multiple genes.
(via Semantic Scholar)
europepmc.org (repository)
Source: Crossref
Added: April 3, 2022
2014 journal article
Furin-Mediated Sequential Delivery of Anticancer Cytokine and Small-Molecule Drug Shuttled by Graphene
Advanced Materials, 27(6), 1021–1028.
MeSH headings : Antineoplastic Combined Chemotherapy Protocols / administration & dosage; Antineoplastic Combined Chemotherapy Protocols / chemistry; Apoptosis / drug effects; Cell Line, Tumor; Cytokines / administration & dosage; Cytokines / chemistry; Diffusion; Doxorubicin / administration & dosage; Doxorubicin / chemistry; Furin / metabolism; Graphite / chemistry; Humans; Nanocapsules / administration & dosage; Nanocapsules / chemistry; Nanocapsules / ultrastructure; Neoplasms, Experimental / drug therapy; Neoplasms, Experimental / pathology; Oxides / chemistry; Particle Size; Peptides / pharmacokinetics; Polyethylene Glycols / chemistry; TNF-Related Apoptosis-Inducing Ligand / administration & dosage; TNF-Related Apoptosis-Inducing Ligand / chemistry; Treatment Outcome
TL;DR:
A cellular protease (furin)-mediated graphene-based nanosystem is developed for co-delivery of a membrane-associated cytokine (tumor-necrosis-factor-related apoptosis-inducing ligand, TRAIL) and an intracellular-acting small-molecule drug (Doxorubicin, DOX).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Crossref
Added: April 3, 2022
2014 journal article
Platelet mechanosensing of substrate stiffness during clot formation mediates adhesion, spreading, and activation
Proceedings of the National Academy of Sciences, 111(40), 14430–14435.
author keywords: mechanotransduction; cell mechanics; platelet cytoskeleton; biomaterials
MeSH headings : Acrylic Resins / metabolism; Blood Coagulation / physiology; Blood Platelets / cytology; Blood Platelets / metabolism; Cell Movement / physiology; Cellular Microenvironment / physiology; Fibrin / metabolism; Fibrinogen / metabolism; Humans; Immobilized Proteins / metabolism; Mechanotransduction, Cellular / physiology; Microscopy, Confocal; P-Selectin / metabolism; Phosphatidylserines / metabolism; Platelet Activation / physiology; Platelet Adhesiveness / physiology; Platelet Aggregation / physiology; Platelet Glycoprotein GPIIb-IIIa Complex / metabolism; Stress, Mechanical; Thrombosis / physiopathology; rac1 GTP-Binding Protein / metabolism
TL;DR:
It is shown for the first time that platelets sense the stiffness of the underlying clot substrate, and increasing substrate stiffness increases platelet adhesion and spreading, and provides biophysical insight into the underlying mechanisms of platelet aggregation and platelet activation heterogeneity during thrombus formation.
(via Semantic Scholar)
Source: Crossref
Added: October 23, 2021
2014 journal article
Direct observation of ligand-induced receptor dimerization with a bioresponsive hydrogel
RSC Advances, 4(110), 65173–65175.
TL;DR:
A simple yet versatile method for the identification of physiologically important receptor dimerization events induced by a ligand is demonstrated and it is identified that one thrombin molecule associates with two GPIbα moieties, which may play a role in efficient hemostatic function by increasing local concentration of G PIbα on platelet surfaces.
(via Semantic Scholar)
Source: Crossref
Added: October 23, 2021
2014 journal article
Ultrasoft microgels displaying emergent platelet-like behaviours
Nature Materials, 13(12), 1108–1114.
TL;DR:
In vitro and in silico analyses demonstrate that PLPs actively collapse fibrin networks, an emergent behaviour that mimics in vivo clot contraction and should inform the future design of a broader class of dynamic, biosynthetic composite materials.
(via Semantic Scholar)
Source: Crossref
Added: October 23, 2021
2014 journal article
Fibrin Fibers: Blocking the B:B Knob-Pocket Interaction
Biophysical Journal, 106(2), 614a.
TL;DR:
It is found that the density and lateral aggregation of fibers was hindered by blocking the b-pockets with the synthetic B-knobs with the fibrinogen solution.
(via Semantic Scholar)
Source: Crossref
Added: October 23, 2021
2014 journal article
Learning from nature – Novel synthetic biology approaches for biomaterial design
Acta Biomaterialia, 10(4), 1761–1769.
author keywords: Synthetic biology; Biomaterials; Directed evolution; Tissue engineering; Virus particles
MeSH headings : Biocompatible Materials / chemistry; Polymers / chemistry; Synthetic Biology / methods; Tissue Scaffolds / chemistry; Virion / chemistry
TL;DR:
The purpose of this review is to highlight the most recent advances in the use of molecular evolution in synthetic biology applications for biomaterial engineering, and to discuss some of the areas in which this approach may be successfully applied in the future.
(via Semantic Scholar)
Source: Crossref
Added: October 23, 2021
2014 journal article
Fibrin-based biomaterials: Modulation of macroscopic properties through rational design at the molecular level
Acta Biomaterialia, 10(4), 1502–1514.
author keywords: Fibrin; Biomaterial design; Fibrin glue; Wound repair; Tissue engineering
MeSH headings : Animals; Biocompatible Materials / chemistry; Biocompatible Materials / pharmacology; Fibrin / chemistry; Fibrin / pharmacology; Humans; Polymerization / drug effects; Proteolysis / drug effects; Tissue Engineering / methods
TL;DR:
Modifying the macroscopic properties of fibrin, such as elasticity and porosity, has been somewhat elusive until recently, yet with a molecular-level rational design approach it can be somewhat easily modified through alterations of molecular interactions key to the protein's polymerization process.
(via Semantic Scholar)
Source: Crossref
Added: August 16, 2021
2014 conference paper
Nonlinear estimation of gait kinematics during functional electrical stimulation and orthosis-based walking
2014 American Control Conference, 4778–4783.
Event: 2014 American Control Conference - ACC 2014 at Portland, OR on June 4-6, 2014
TL;DR:
A state-dependent coefficient (SDC)-based nonlinear estimator is developed to estimate the lower limb angles which can be used to decide when the FES signal should be applied to the leg during the different phases of walking.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions
(OpenAlex)
Sources: ORCID, Crossref
Added: August 12, 2021
2014 journal article
Dynamic optimization of FES and orthosis-based walking using simple models
IEEE Transactions on Neural Systems and Rehabilitation Engineering, 22(1), 114–126.
Contributors: N. Sharma* , V. Mushahwar * & R. Stein*
author keywords: Dynamic optimization; functional electrical stimulation; hybrid orthosis; optimal control; walking model
MeSH headings : Computer Simulation; Electric Stimulation Therapy / methods; Gait; Gait Disorders, Neurologic / physiopathology; Gait Disorders, Neurologic / rehabilitation; Humans; Leg / physiopathology; Models, Biological; Muscle Contraction; Muscle, Skeletal / physiopathology; Orthotic Devices; Range of Motion, Articular; Therapy, Computer-Assisted / methods
TL;DR:
Dynamic optimization can be utilized to compute gait parameters such as step length, steady state velocity, and joint angle trajectories in future clinical implementation of FES and orthosis-based walking.
(via Semantic Scholar)
Source: ORCID
Added: August 12, 2021
2014 conference paper
A semi-active hybrid neuroprosthesis for restoring lower limb function in paraplegics
2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, 2557–2560.
Contributors: N. Kirsch*, N. Alibeji*, L. Fisher *, C. Gregory* & N. Sharma*
MeSH headings : Electric Stimulation Therapy / instrumentation; Gait / physiology; Hip / physiopathology; Humans; Knee / physiopathology; Lower Extremity / physiopathology; Neural Prostheses; Orthotic Devices; Paraplegia / rehabilitation; Walking / physiology
TL;DR:
The initial testing of a semi-active hybrid walking neuroprosthesis using a finite state machine that uses a recently developed nonlinear controller for position tracking control of the hip motors and cues from the hip angle to actuate FES and other components is demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: August 12, 2021
2014 conference paper
Model predictive control-based dynamic control allocation in a hybrid neuroprosthesis
ASME 2014 Dynamic Systems and Control Conference, DSCC 2014, 3.
Contributors: N. Kirsch*, N. Alibeji* & N. Sharma*
TL;DR:
It is proposed that a model predictive control (MPC)-based control design can be used to optimally distribute joint torque, and can adapt as the muscle fatigue sets in.
(via Semantic Scholar)
Source: ORCID
Added: August 12, 2021
2014 conference paper
A state synchronization controller for functional electrical stimulation-based telerehabilitation
ASME 2014 Dynamic Systems and Control Conference, DSCC 2014, 3.
Contributors: N. Alibeji*, N. Kirsch*, A. Sethi * & N. Sharma*
TL;DR:
A position-synchronization controller for functional electrical stimulation (FES)-based telerehabilitation synchronizes an FES-driven human limb with a remote physical therapist’s manipulator despite constant bilateral communication delays.
(via Semantic Scholar)
Source: ORCID
Added: August 12, 2021
Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.
Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.
