Works Published in 2014
Displaying works 21 - 35 of 35 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2014 journal article
A single codon insertion in PICALM is associated with development of familial subvalvular aortic stenosis in Newfoundland dogs
HUMAN GENETICS, 133(9), 1139–1148.
MeSH headings : Animals; Aortic Stenosis, Subvalvular / genetics; Aortic Stenosis, Subvalvular / pathology; Aortic Stenosis, Subvalvular / veterinary; Base Sequence; Case-Control Studies; Clathrin / antagonists & inhibitors; Clathrin / genetics; Codon / genetics; Dog Diseases / genetics; Dog Diseases / pathology; Dogs; Female; Genetic Predisposition to Disease; Genome-Wide Association Study; Male; Molecular Sequence Data; Monomeric Clathrin Assembly Proteins / chemistry; Monomeric Clathrin Assembly Proteins / genetics; Monomeric Clathrin Assembly Proteins / metabolism; Mutagenesis, Insertional; Pedigree; Phosphatidylinositols / metabolism; Prospective Studies; Protein Conformation; Sequence Analysis, RNA; Sex Factors; Xenopus laevis / embryology
TL;DR:
A three-nucleotide exonic insertion in phosphatidylinositol-binding clathrin assembly protein (PICALM) that is associated with the development of SAS in Newfoundlands is identified and the role of PICALM in OFT development may aid in future molecular and genetic investigations into other congenital heart defects of various species.
(via Semantic Scholar)
link.springer.com (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
14. Life Below Water
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Hypoxia controls iron metabolism and glutamate secretion in retinal pigmented epithelial cells
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS, 1840(10), 3138–3144.
author keywords: Iron transport; Glutamate; Hypoxia; Blood-ocular barriers
MeSH headings : Animals; Cell Hypoxia; Cells, Cultured; Dogs; Epithelial Cells / metabolism; Epithelial Cells / pathology; Glutamic Acid / metabolism; Humans; Iron / metabolism; Oxidation-Reduction; Retinal Pigment Epithelium / metabolism; Retinal Pigment Epithelium / pathology; Stroke / metabolism; Stroke / pathology
TL;DR:
Iron, a key catalyst of free radical generation, is removed from RPE under hypoxic conditions which may help protect RPE from oxidative stress and indicate the importance of using polarized tight junctional cells as more physiologically relevant models for blood-barrier-like systems.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Equine herpesvirus type 1 pUL56 modulates innate responses of airway epithelial cells
VIROLOGY, 464, 76–86.
author keywords: Equine herpesvirus-1; Respiratory epithelium; pUL56; Innate immunity
MeSH headings : Animals; Chemokines / genetics; Chemokines / immunology; Epithelial Cells / immunology; Epithelial Cells / virology; Herpesvirus 1, Equid / genetics; Herpesvirus 1, Equid / immunology; Horse Diseases / genetics; Horse Diseases / immunology; Horse Diseases / virology; Horses; Host-Pathogen Interactions; Immunity, Innate; Leukocytes, Mononuclear / immunology; Leukocytes, Mononuclear / virology; Respiratory Mucosa / cytology; Respiratory Mucosa / immunology; Respiratory Mucosa / virology; Viral Nonstructural Proteins / genetics; Viral Nonstructural Proteins / immunology
TL;DR:
Results suggest a role for EHV-1 pUL56 in modulation of antigen presentation, cytokine expression and chemotaxis at the respiratory epithelium, but not in PBMC.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Natural History of Arrhythmogenic Right Ventricular Cardiomyopathy in the Boxer Dog: A Prospective Study
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(4), 1214–1220.
author keywords: Boxer; Holter; Striatin; Sudden death; Ventricular premature complex
MeSH headings : Age Factors; Animals; Arrhythmogenic Right Ventricular Dysplasia / genetics; Arrhythmogenic Right Ventricular Dysplasia / physiopathology; Arrhythmogenic Right Ventricular Dysplasia / veterinary; Case-Control Studies; Death, Sudden / veterinary; Dog Diseases / genetics; Dog Diseases / physiopathology; Dogs; Female; Genotype; Male; Prospective Studies; Ventricular Premature Complexes / physiopathology; Ventricular Premature Complexes / veterinary
TL;DR:
Arrhythmogenic right ventricular cardiomyopathy is a disease of middle age and frequently is associated with the striatin deletion, and the prognosis in many affected dogs is good.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2014 journal article
Prevalence and classification of chronic kidney disease in cats randomly selected from four age groups and in cats recruited for degenerative joint disease studies
JOURNAL OF FELINE MEDICINE AND SURGERY, 16(6), 465–472.
MeSH headings : Age Factors; Animals; Cat Diseases / classification; Cat Diseases / diagnosis; Cat Diseases / epidemiology; Cats; Osteoarthritis / classification; Osteoarthritis / epidemiology; Osteoarthritis / veterinary; Prevalence; Renal Insufficiency, Chronic / classification; Renal Insufficiency, Chronic / epidemiology; Renal Insufficiency, Chronic / veterinary; Retrospective Studies; Risk Factors
TL;DR:
Significant concurrence between CKD and DJD in cats of all ages is found, indicating the need for increased screening for CKD when selecting DJD treatments and the idea of a relationship and causal commonality between CKd andDJD owing to the striking concurrence across age groups and life stages.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Innate immune responses of airway epithelial cells to infection with Equine herpesvirus-1
VETERINARY MICROBIOLOGY, 170(1-2), 28–38.
author keywords: EHV-1; Epithelium; Innate immunity; Equine
MeSH headings : Animals; Cells, Cultured; Chemokines / genetics; Chemokines / immunology; Cytokines / genetics; Cytokines / immunology; Epithelial Cells / immunology; Epithelial Cells / virology; Gene Expression Regulation / immunology; Herpesviridae Infections / immunology; Herpesviridae Infections / veterinary; Herpesvirus 1, Equid / immunology; Horse Diseases / immunology; Horses; Host-Pathogen Interactions / immunology; Immunity, Innate / immunology; Respiratory Mucosa / immunology; Respiratory Mucosa / virology; Virus Internalization
TL;DR:
An initial characterization of the early immune response to EHV-1 at the epithelial cell barrier is provided and it is shown that, while EHv-1 maintains induction of an inflammatory response, it causes an attenuation of IFN-gamma responses and down-modulates expression of M HC-I and MHC-II, which are important molecules for antigen presentation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
The efficacy of alfaxalone for immersion anesthesia in koi carp (Cyprinus carpio)
VETERINARY ANAESTHESIA AND ANALGESIA, 41(4), 398–405.
author keywords: alfaxalone; Alfaxan; anesthetic; Cyprinus carpio; fish; koi carp
MeSH headings : Anesthetics / administration & dosage; Anesthetics / pharmacology; Animals; Bicarbonates / blood; Carbon Dioxide / blood; Carps; Cross-Over Studies; Drug Administration Routes / veterinary; Hydrogen-Ion Concentration; Lactates / blood; Oxygen / blood; Pregnanediones / administration & dosage; Pregnanediones / pharmacology; Temperature
TL;DR:
Administration of alfaxalone, via water immersion, as an induction and maintenance anesthesia agent provided rapid and reliable anesthesia of koi with no mortality.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Proteomic Characterization of Equine Cerebrospinal Fluid
JOURNAL OF EQUINE VETERINARY SCIENCE, 34(3), 451–458.
author keywords: Equine; Cerebrospinal fluid; Proteomics; Normalized spectral abundance factor; Gene ontology
TL;DR:
Theses results provide an optimized protocol for analysis of equine CSF and lay the groundwork for future studies involving the study of equines CSF in the context of pathogenic disease states.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Biomechanical Evaluation of the Influence of an Intramedullary Pin on the Stability of a Feline Ilial Fracture Model Stabilized With a Bone Plate
VETERINARY SURGERY, 43(2), 114–119.
MeSH headings : Animals; Biomechanical Phenomena; Bone Plates; Cadaver; Cats / surgery; Fracture Fixation, Internal / instrumentation; Fracture Fixation, Internal / methods; Fracture Fixation, Internal / veterinary; Fractures, Bone / surgery; Fractures, Bone / veterinary; Ilium / pathology; Ilium / surgery
TL;DR:
The P + P constructs were not significantly stronger than plates alone in this acutely loaded cadaveric model and no biomechanical advantage was demonstrated.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 article
"Equine research - our only business': The Grayson-Jockey Club Research Foundation
Lunn, D. P., Antczak, D. F., McCue, P., Richardson, D., & Scollaly, M. (2014, July). EQUINE VETERINARY JOURNAL, Vol. 46, pp. 515–516.
MeSH headings : Animals; Foundations / organization & administration; Horse Diseases; Horses; Research / economics
TL;DR:
An analysis of the past 15 years of GJCRF research-funding patterns demonstrates some striking trends, including laminitis, colic, musculoskeletal diseases and racing injury, and infectious disease, followed by noninfectious respiratory disease and diseases of the foal.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Evaluation of a point-of-care anticoagulant rodenticide test for dogs
JOURNAL OF VETERINARY EMERGENCY AND CRITICAL CARE, 24(2), 168–173.
author keywords: bedside; canine; poisoning; rodenticide; toxicology
MeSH headings : Animals; Anticoagulants / blood; Anticoagulants / chemistry; Dogs / blood; Molecular Structure; Point-of-Care Systems; Rodenticides / blood; Rodenticides / chemistry
TL;DR:
The point-of-care test kit was able to detect a single anticoagulant rodenticide (warfarin) at concentrations below the manufacturer's recommended limit of detection, but was unable to detect any other antICOagulants rodenticide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 journal article
Prevalence of onychectomy in cats presented for veterinary care near Raleigh, NC and educational attitudes toward the procedure
Veterinary Anaesthesia and Analgesia, 41(1), 48–53.
author keywords: cat; declaw; education; onychectomy; pain; sterilization
MeSH headings : Animals; Cats / surgery; Education, Veterinary; Female; Hoof and Claw / surgery; Male; North Carolina; Surgical Procedures, Operative / education; Surgical Procedures, Operative / veterinary
TL;DR:
Almost 21% of cats seen in veterinary hospitals near Raleigh, NC were declawed and there appears to be a discrepancy between the popularity of the onychectomy procedure and the emphasis placed on relevant instruction in veterinary schools in the USA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
4. Quality Education
(OpenAlex)
Sources: Web Of Science, Crossref
Added: August 6, 2018
2014 journal article
Identification of PDE5A:E90K: A Polymorphism in the Canine Phosphodiesterase 5A Gene Affecting Basal cGMP Concentrations of Healthy Dogs
JOURNAL OF VETERINARY INTERNAL MEDICINE, 28(1), 78–83.
author keywords: Individualized medicine; Pharmacogenomics; Pulmonary hypertension; Sildenafil citrate; Single nucleotide polymorphisms
MeSH headings : Amino Acid Sequence; Animals; Cyclic GMP / metabolism; Cyclic Nucleotide Phosphodiesterases, Type 5 / genetics; Cyclic Nucleotide Phosphodiesterases, Type 5 / metabolism; DNA / chemistry; DNA / genetics; Dogs / genetics; Dogs / metabolism; Molecular Sequence Data; Polymerase Chain Reaction / veterinary; Polymorphism, Single Nucleotide / genetics; Sequence Alignment; Sequence Analysis, DNA
TL;DR:
A polymorphism exists in the canine PDE5A gene that is associated with variable circulating cGMP concentrations in healthy dogs and warrants investigation in diseases such as pulmonary hypertension.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2014 journal article
Perianesthetic morbidity and mortality in dogs undergoing cervical and thoracolumbar spinal surgery
VETERINARY ANAESTHESIA AND ANALGESIA, 41(2), 137–144.
author keywords: surgery; spinal; morbidity; cervical; mortality; dog
MeSH headings : Anesthesia / adverse effects; Anesthesia / veterinary; Animals; Dogs; Female; Intervertebral Disc Displacement / surgery; Intervertebral Disc Displacement / veterinary; Male; Perioperative Period / adverse effects; Perioperative Period / veterinary; Postoperative Complications / veterinary
TL;DR:
Overall, dogs undergoing cervical spinal surgery were less likely to survive until discharge compared with dogs undergoing thoracolumbar spinal surgery, anddogs undergoing cervical intervertebral disc decompression surgery should be considered at risk for aspiration pneumonia.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2014 article
Pathology in Practice Diagnosis and case summary: LGL lymphoma in a cat
Meichner, K., Palerme, J.-S., & Neel, J. A. (2014, January 15). JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, Vol. 244, pp. 167–169.
Contributors: K. Meichner n, J. Palerme* & J. Neel*
MeSH headings : Animals; Cat Diseases / diagnosis; Cat Diseases / pathology; Cats; Female; Lymphoma / classification; Lymphoma / pathology; Lymphoma / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, NC State University Libraries, ORCID
Added: August 6, 2018
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