College of Sciences Administration

Works Published in 2013

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Displaying works 1 - 20 of 28 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2013 journal article

Designing endocrine disruption out of the next generation of chemicals

Green Chem., 15(1), 181–198.

By: T. Schug*, R. Abagyan*, B. Blumberg*, T. Collins*, D. Crews*, P. DeFur*, S. Dickerson, T. Edwards* ...

Source: Crossref
Added: September 8, 2020

2013 journal article

Developing predictive approaches to characterize adaptive responses of the reproductive endocrine axis to aromatase inhibition: II. Computational modeling

Toxicological Sciences, 133(2), 234–247.

By: M. Breen, D. Villeneuve, G. Ankley, D. Bencic, M. Breen, K. Watanabe, A. Lloyd, R. Conolly

Source: ORCID
Added: April 8, 2020

2013 journal article

Developmental timing of mutations revealed by whole-genome sequencing of twins with acute lymphoblastic leukemia

Proceedings of the National Academy of Sciences, 110(18), 7429–7433.

By: Y. Ma*, S. Dobbins*, A. Sherborne*, D. Chubb*, M. Galbiati*, G. Cazzaniga*, C. Micalizzi*, R. Tearle* ...

author keywords: fusion gene; copy number variants
MeSH headings : Child; Child, Preschool; DNA Mutational Analysis; Genome, Human / genetics; Humans; Mutation / genetics; Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics; Time Factors
TL;DR: This work sequenced the whole genomes of leukemic cells from two twin pairs with ALL to comprehensively characterize acquired somatic mutations in ALL, elucidating the developmental timing of all genetic lesions. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Crossref, ORCID
Added: February 24, 2020

2013 book

Treetops at risk: Challenges of global canopy ecology and conservation

New York: Springer.

Margaret Lowman

Ed(s): M. Lowman, S. Devy & T. Ganesh

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Decoding the language of epigenetics during neural development is key for understanding development as well as developmental neurotoxicity

EPIGENETICS, 8(11), 1128–1132.

author keywords: neurodevelopmental toxicity; bisphenol A; chloride shift; KCC2; SLC12A5
MeSH headings : Air Pollutants, Occupational / adverse effects; Animals; Benzhydryl Compounds / adverse effects; Cerebral Cortex / metabolism; Chlorides / metabolism; Epigenesis, Genetic / drug effects; Female; Humans; Male; Nerve Tissue Proteins / metabolism; Neurons / metabolism; Phenols / adverse effects; Response Elements; Symporters / biosynthesis
TL;DR: This commentary highlights recent discoveries in the arena of research at the interface of environmental toxicology and developmental neuroscience relating to toxicity mechanisms of bisphenol A, including the discovery that BPA disrupts the chloride shift in a sex-specific manner by recruiting epigenetics mechanisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Effects of environmental endocrine disruptors and phytoestrogens on the Kisspeptin system

Kisspeptin Signaling in Reproductive Biology, 784, 455–479.

By: H. Patisaul

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

Promoting ecoliteracy through research service-learning and citizen science

FRONTIERS IN ECOLOGY AND THE ENVIRONMENT, 11(10), 565–566.

Source: Web Of Science
Added: August 6, 2018

2013 journal article

Modeling the Dynamics of a Non-Limited and a Self-Limited Gene Drive System in Structured Aedes aegypti Populations

PLoS ONE, 8(12), e83354.

Ed(s): Z. Adelman

MeSH headings : Aedes / genetics; Animals; Animals, Genetically Modified / genetics; Dengue / genetics; Dengue / prevention & control; Dengue / transmission; Female; Gene Frequency; Genetic Engineering; Genetics, Population; Homozygote; Insect Vectors / genetics; Male; Models, Genetic; Mosquito Control; Peru; Population Dynamics; Time Factors
TL;DR: This study provides guidelines for operational approaches to population replacement genetic strategies, as well as illustrates the use of detailed spatial models to assist in safe and efficient implementation of such novel genetic strategies. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2013 journal article

Viral Substitution Rate Variation Can Arise from the Interplay between Within-Host and Epidemiological Dynamics

AMERICAN NATURALIST, 182(4), 494–513.

By: S. Scholle*, R. Ypma*, A. Lloyd n & K. Koelle*

author keywords: substitution rate variation; RNA virus evolution; within-host dynamics; epidemiological model; disease dynamics
MeSH headings : Evolution, Molecular; Host-Pathogen Interactions; Models, Genetic; RNA Viruses / genetics; Species Specificity
TL;DR: This work shows that even in neutrally evolving viral populations, epidemiological dynamics can alter substitution rates via the interplay between within-host replication dynamics and population-level disease dynamics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

A Reduce and Replace Strategy for Suppressing Vector-Borne Diseases: Insights from a Stochastic, Spatial Model

PLOS ONE, 8(12).

MeSH headings : Aedes / genetics; Aedes / virology; Animals; Animals, Genetically Modified; Calibration; Computer Simulation; Dengue Virus / physiology; Female; Genotype; Insect Vectors / virology; Male; Models, Theoretical; Ovum / metabolism; Stochastic Processes
TL;DR: It is found this “reduce and replace” strategy can decrease the frequency of competent vectors below 50% two years after releases end, and appears preferable to releasing a strain carrying only a female-killing gene, which is likely to merely result in temporary population suppression. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Sex specific impact of perinatal bisphenol A (BPA) exposure over a range of orally administered doses on rat hypothalamic sexual differentiation

NEUROTOXICOLOGY, 36, 55–62.

By: K. McCaffrey n, B. Jones*, N. Mabrey n, B. Weiss*, S. Swan* & H. Patisaul n

author keywords: Endocrine disruption; Estrogen; Hypothalamus; Sexually dimorphic; Dopamine
MeSH headings : Administration, Oral; Air Pollutants, Occupational / toxicity; Analysis of Variance; Animals; Benzhydryl Compounds / administration & dosage; Benzhydryl Compounds / toxicity; Calbindins / metabolism; Cell Count; Dose-Response Relationship, Drug; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Phenols / administration & dosage; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / chemically induced; Rats; Rats, Long-Evans; Sex Differentiation / physiology; Tyrosine 3-Monooxygenase / metabolism
TL;DR: It is demonstrated that early life oral exposure to BPA at levels well below the current No Observed Adverse Effect Level (NOAEL) of 50mg/kg/day can alter sex specific hypothalamic morphology in the rat. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Hydrogen peroxide and extracellular signal-related kinase 1/2 pathway regulate ferritin levels in retinal pigmented and lens epithelial cells

Molecular Vision, 19, 2106–2112.

By: M. Lall, J. Harned & M. McGahan

Source: NC State University Libraries
Added: August 6, 2018

2013 journal article

A Reduce and Replace Strategy for Suppressing Vector-Borne Diseases: Insights from a Deterministic Model

PLOS ONE, 8(9).

MeSH headings : Aedes / genetics; Aedes / physiology; Animals; Communicable Disease Control / methods; Dengue / prevention & control; Dengue / transmission; Female; Genetic Engineering; Insect Vectors / genetics; Insect Vectors / physiology; Male; Models, Theoretical; Time Factors
TL;DR: It is shown that repeated R&R releases may lead to a temporary decrease in mosquito population density and, in the absence of fitness costs associated with the anti-pathogen gene, a long-term decrease in competent vector population density. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Regulation of Aedes aegypti Population Dynamics in Field Systems: Quantifying Direct and Delayed Density Dependence

The American Journal of Tropical Medicine and Hygiene, 89(1), 68–77.

By: R. Walsh n, F. Gould n, A. Lloyd n, T. Scott n, J. Ramsey n, L. Valerio n, L. Facchinelli n, C. Aguilar n

MeSH headings : Aedes / growth & development; Aedes / physiology; Animals; Body Size; Female; Larva; Male; Mexico; Mosquito Control; Population Density; Population Dynamics; Seasons; Wings, Animal / anatomy & histology
TL;DR: Results indicate that control methods attempting to reduce mosquito populations may be counteracted by density-dependent population regulation, and specifically on larval survival, larval development, and adult body size. (via Semantic Scholar)
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2013 article

Turbulence and magnetic field amplification from spiral SASI modes in core-collapse supernovae

Endeve, E., Cardall, C. Y., Budiardja, R. D., Mezzacappa, A., & Blondin, J. M. (2013, July). PHYSICA SCRIPTA, Vol. T155.

Sources: Web Of Science, ORCID
Added: August 6, 2018

2013 journal article

Home Life: Factors Structuring the Bacterial Diversity Found within and between Homes

PLOS ONE, 8(5).

MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Biodiversity; Genes, Bacterial; High-Throughput Nucleotide Sequencing; North Carolina; Polymerase Chain Reaction; RNA, Transfer / genetics; Residence Characteristics
TL;DR: The presence of dogs had a significant effect on bacterial community composition in multiple locations within homes as the homes occupied by dogs harbored more diverse communities and higher relative abundances of dog-associated bacterial taxa. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2013 journal article

AZIMUTHAL DENSITY VARIATIONS AROUND THE RIM OF TYCHO's SUPERNOVA REMNANT

ASTROPHYSICAL JOURNAL, 770(2).

author keywords: dust, extinction; ISM: supernova remnants
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018

2013 journal article

X-RAY EMISSION FROM STRONGLY ASYMMETRIC CIRCUMSTELLAR MATERIAL IN THE REMNANT OF KEPLER'S SUPERNOVA

The Astrophysical Journal, 764(1), 63.

author keywords: ISM: individual objects (G4.5+6.8); ISM: supernova remnants; supernovae: general; X-rays: ISM
Sources: Web Of Science, Crossref, NC State University Libraries
Added: August 6, 2018

2013 journal article

Three-dimensional numerical investigations of the morphology of Type Ia SNRs

Monthly Notices of the Royal Astronomical Society, 429(4), 3099–3113.

By: D. Warren n & J. Blondin n

author keywords: hydrodynamics; instabilities; ISM: supernova remnants
Sources: Web Of Science, Crossref, ORCID
Added: August 6, 2018

2013 journal article

Accumulation and Endocrine Disrupting Effects of the Flame Retardant Mixture Firemaster (R) 550 in Rats: An Exploratory Assessment

JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY, 27(2), 124–136.

By: H. Patisaul n, S. Roberts*, N. Mabrey n, K. McCaffrey n, R. Gear*, J. Braun*, S. Belcher*, H. Stapleton*

author keywords: Anxiety; Cardiac Hypertrophy; Endocrine Disruptor; Flame Retardants; Metabolic Syndrome; Metabolism; Obesity; Obesogen; Polybrominated Diphenyl Ethers; Rodents
MeSH headings : Animals; Cardiomegaly / blood; Cardiomegaly / chemically induced; Cardiomegaly / pathology; Endocrine System / metabolism; Endocrine System / pathology; Endocrine System / physiology; Female; Flame Retardants / adverse effects; Male; Maternal Exposure / adverse effects; Obesity / blood; Obesity / chemically induced; Obesity / pathology; Pregnancy; Prenatal Exposure Delayed Effects / blood; Prenatal Exposure Delayed Effects / pathology; Rats; Rats, Wistar; Thyroxine / blood
TL;DR: Results are the first to implicate FM 550 as an endocrine disruptor and an obesogen at environmentally relevant levels and induced phenotypic hallmarks associated with metabolic syndrome in the offspring. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

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