Works Published in 2019
Displaying all 13 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2019 journal article
Rodent gene drives for conservation: opportunities and data needs
Proceedings of the Royal Society B: Biological Sciences.
author keywords: rodent; mice; rat; biodiversity; gene drive; island
MeSH headings : Animals; Biodiversity; Conservation of Natural Resources / methods; Gene Drive Technology; Introduced Species; Islands; Reproduction; Rodentia
TL;DR:
What is currently known about natural and developing synthetic gene drive systems in mice, some key areas where key knowledge gaps exist, findings in a variety of disciplines relevant to those gaps and a brief consideration of how engagement at the regulatory, stakeholder and community levels can accompany and contribute to this effort.
(via Semantic Scholar)
royalsocietypublishing.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: ORCID
Added: May 14, 2020
2019 article
Optimizing the deployment of ultra-low volume and indoor residual spraying for dengue outbreak response
Cavany, S. M., España, G., Lloyd, A. L., Waller, L. A., Kitron, U., Astete, H., … Perkins, T. A. (2019, October 2).
TL;DR:
Although spraying twice each year is likely to avert the most infections, the results indicate that a threshold-based strategy can become an alternative to better balance the translation of spraying effort into impact, particularly if used with a residual insecticide.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: April 8, 2020
2019 article
After the honeymoon, the divorce: unexpected outcomes of disease control measures against endemic infections
Hollingsworth, B., Okamoto, K. W., & Lloyd, A. L. (2019, April 19). (Vol. 4). Vol. 4.
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: April 8, 2020
2019 journal article
PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation
ENDOCRINOLOGY, 160(11), 2748–2758.
MeSH headings : Animals; Female; Halogenated Diphenyl Ethers / pharmacokinetics; Humans; Male; Membrane Transport Proteins / metabolism; Placenta / metabolism; Pregnancy; Rats, Wistar; Thyroid Hormones / metabolism
TL;DR:
The placenta is a significant modifier of fetal exposures, and that polybrominated diphenyl ethers are impacting TH regulation in a sex-specific manner during this critical window of development.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Web Of Science, ORCID
Added: January 27, 2020
2019 journal article
Consistent slow exhumation in a late Cenozoic glaciated landscape: The Presidential and Carter ranges of the White Mountains in New Hampshire, USA
GEOMORPHOLOGY, 345.
author keywords: Passive margins; Glacial Erosion; Low Temperature Thermochronology; In situ Terrestrial Cosmogenic Nuclide Be-10
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: January 6, 2020
2019 journal article
Sex-specific behavioral effects following developmental exposure to tetrabromobisphenol A (TBBPA) in Wistar rats
NEUROTOXICOLOGY, 75, 136–147.
author keywords: brain; anxiety; endocrine disruptions; sex differences; hyperactivity; neural; sexually dimorphic; neurotoxic; flame retardants; elevated plus maze; neurodevelopment
MeSH headings : Animals; Behavior, Animal / drug effects; Dose-Response Relationship, Drug; Endocrine Disruptors / toxicity; Flame Retardants / toxicity; Maze Learning / drug effects; Motor Activity / drug effects; Polybrominated Biphenyls / toxicity; Rats; Rats, Wistar / growth & development; Sex Factors
TL;DR:
It is demonstrated that exposure to environmental contaminants, like TBBPA, can have sex-specific effects on behavior highlighting the vulnerability of the developing brain.
(via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: December 16, 2019
2019 journal article
Rates of rockwall slope erosion in the upper Bhagirathi catchment, Garhwal Himalaya
EARTH SURFACE PROCESSES AND LANDFORMS, 44(15), 3108–3127.
author keywords: supraglacial processes; sediment flux; glacier; climate; cosmogenic isotopes
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: December 9, 2019
2019 article
Cosmogenic Be-10 and equilibrium-line altitude dataset of Holocene glacier advances in the Himalayan-Tibetan orogen
Saha, S., Owen, L. A., Orr, E. N., & Caffee, M. W. (2019, October). DATA IN BRIEF, Vol. 26.
author keywords: Cosmogenic nuclides; Equilibrium-line altitudes; Holocene; Central asia; Glaciation
TL;DR:
High-frequency Holocene glacier chronostratigraphies are reconstructed in 79 glaciated valleys across the orogen using 519 published and 16 new terrestrial cosmogenic 10Be exposure age dataset to serve as an essential archive for future studies focusing on the cryospheric and environmental changes in the Himalayan-Tibetan orogen.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science; OpenAlex)
Source: Web Of Science
Added: November 25, 2019
2019 journal article
Locally Fixed Alleles: A method to localize gene drive to island populations
SCIENTIFIC REPORTS, 9.
MeSH headings : Alleles; Animals; Biodiversity; Islands
TL;DR:
This paper proposes the “Locally Fixed Alleles” approach as a novel means for localizing elimination by a drive to an island population that exhibits significant genetic isolation from neighboring populations and explores the feasibility and degree of localization that can be achieved.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID
Added: November 18, 2019
2019 journal article
High-frequency Holocene glacier fluctuations in the Himalayan-Tibetan orogen
QUATERNARY SCIENCE REVIEWS, 220, 372–400.
author keywords: Holocene; Glaciation Central Asia; Cosmogenic isotopes; Paleoclimate modeling; Equilibrium-line altitudes
UN Sustainable Development Goal Categories
13. Climate Action
(Web of Science)
Source: Web Of Science
Added: October 21, 2019
2019 journal article
Perinatal bisphenol A (BPA) exposure alters brain oxytocin receptor (OTR) expression in a sex- and region- specific manner: A CLARITY-BPA consortium follow-up study
NEUROTOXICOLOGY, 74, 139–148.
author keywords: Behavior; Estrogen; Endocrine disruption; Sexual differentiation; Neuroendocrine; Oxytocin
MeSH headings : Animals; Animals, Newborn; Benzhydryl Compounds / toxicity; Brain Chemistry / drug effects; Endocrine Disruptors / toxicity; Ethinyl Estradiol / toxicity; Female; Hypothalamus / drug effects; Hypothalamus / metabolism; Male; Oxytocin / biosynthesis; Phenols / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / metabolism; Rats; Rats, Sprague-Dawley; Receptors, Oxytocin / biosynthesis; Septal Nuclei / drug effects; Septal Nuclei / metabolism; Sex Characteristics
TL;DR:
Prenatal exposure to BPA can eliminate sex differences in OTR expression in three hypothalamic regions, and that male O TR expression may be more susceptible, and a sexually dimorphic sub-region of the BNST not previously reported in juvenile rats is identified that is also susceptible to B PA.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 21, 2019
2019 journal article
Tethered homing gene drives: A new design for spatially restricted population replacement and suppression
EVOLUTIONARY APPLICATIONS, 12(8), 1688–1702.
author keywords: Cas; CRISPR; gene drive; genetic engineering; population alteration; underdominance
TL;DR:
A new gene drive system, Tethered Homing (TH), is presented, with improved capacity for localized population alteration, especially for population suppression, and the ability to gradually adjust the genetic load in a population after the initial alteration, with minimal additional release effort.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: October 21, 2019
2019 article
Pest management by genetic addiction
Gould, F., Dhole, S., & Lloyd, A. L. (2019, March 26). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, Vol. 116, pp. 5849–5851.
MeSH headings : Gene Drive Technology; Pest Control
TL;DR:
The work of Oberhofer et al. (1) adds substantially to a growing field within genetic engineering, often termed gene drive research, in which selfish genetic elements overcome the rules of Mendelian inheritance and push transgenes into a population.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: April 15, 2019
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