Bioinformatics Research Center

Works Published in 2002

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Displaying all 7 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2002 journal article

Discussion on the meeting on 'Statistical modelling and analysis of genetic data'

Journal of the Royal Statistical Society: Series B (Statistical Methodology), 64(4), 737–775.

By: D. Balding, A. Carothers, J. Marchini, L. Cardon, A. Vetta, B. Griffiths, B. Weir, W. Hill ...

TL;DR: An unavoidable commitment arising unexpectedly in the 18 hours before the meeting robbed me of the final preparation, so that comments at the meeting were poorly presented, and to leave enough space I shall omit my introductory comments about the role of statisticians in bioinformatics. (via Semantic Scholar)
Source: Crossref
Added: April 4, 2021

2002 journal article

Divergence time and evolutionary rate estimation with multilocus data

SYSTEMATIC BIOLOGY, 51(5), 689–702.

author keywords: Markov chain Monte Carlo; Metropolis-Hastings algorithm; molecular clock; phylogeny
MeSH headings : Algorithms; Bayes Theorem; Biological Evolution; Evolution, Molecular; Markov Chains; Models, Genetic; Monte Carlo Method; Phylogeny; Plants / genetics; Time Factors
TL;DR: Bayesian methods for estimating evolutionary divergence times are extended to multigene data sets, and a technique is described for detecting correlated changes in evolutionary rates among genes. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Simultaneous maximum likelihood estimation of linkage and linkage phases in outcrossing species

THEORETICAL POPULATION BIOLOGY, 61(3), 349–363.

By: R. Wu*, C. Ma, I. Painter n & Z. Zeng n

author keywords: EM algorithm; linkage phase; outcrossing species; partially informative marker; posterior probability; recombination fraction
MeSH headings : Algorithms; Alleles; Crosses, Genetic; Gene Frequency; Genetic Linkage; Genetic Markers; Likelihood Functions; Markov Chains; Models, Genetic; Plants / genetics; Species Specificity
TL;DR: A general maximum-likelihood-based algorithm for simultaneously estimating linkage and linkage phases for a mixed set of different marker types containing fully informative markers and partially informative markers in a full-sib family derived from two outbred parent plants is presented. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Estimation of effective population size of HIV-1 within a host: A pseudomaximum-likelihood approach

Genetics, 160(4), 1283–1293.

By: T. Seo, J. Thorne, M. Hasegawa & H. Kishino

Source: NC State University Libraries
Added: August 6, 2018

2002 journal article

A viral sampling design for testing the molecular clock and for estimating evolutionary rates and divergence times

BIOINFORMATICS, 18(1), 115–123.

By: T. Seo, J. Thorne*, M. Hasegawa & H. Kishino

MeSH headings : Computational Biology; Evolution, Molecular; HIV-1 / genetics; HIV-1 / isolation & purification; Humans; Models, Genetic; Models, Statistical; Time Factors; Viruses / genetics; Viruses / isolation & purification
TL;DR: Variation in sequence isolation times can be intentionally adjusted to increase the power of hypothesis tests and to reduce the uncertainty of evolutionary parameter estimates, but this fact has received little previous attention. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Linkage mapping of sex-specific differences

GENETICAL RESEARCH, 79(1), 85–96.

By: R. Wu*, C. Ma, S. Wu* & Z. Zeng n

MeSH headings : Algorithms; Animals; Chromosome Mapping / methods; Female; Genetic Markers; Humans; Likelihood Functions; Male; Recombination, Genetic / genetics; Sex Characteristics
TL;DR: In this paper, a general EM-based algorithm is presented to estimate sex-specific recombination fractions for a mixed set of molecular markers segregating differently in a full-sib family derived from two heterozygous parents. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2002 journal article

Modeling epistasis of quantitative trait loci using Cockerham's model

Genetics, 160(3), 1243–1261.

By: C. Kao & Z. Zeng

Source: NC State University Libraries
Added: August 6, 2018

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