Works Published in 2007
Displaying all 12 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2007 journal article
The Hill–Robertson effect is a consequence of interplay between linkage, selection and drift: a commentary on ‘The effect of linkage on limits to artificial selection’ by W. G. Hill and A. Robertson
Genetics Research, 89(5-6), 309–310.
MeSH headings : Alleles; Genetic Drift; Genetic Linkage; Population Density; Selection, Genetic
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: July 20, 2019
2007 journal article
The role of epistasis in the manifestation of heterosis: A systems-oriented approach
GENETICS, 177(3), 1815–1825.
MeSH headings : Animals; Breeding; Chromosome Mapping; Epistasis, Genetic; Genes, Dominant; Genetic Markers; Hybrid Vigor; Mathematics; Models, Genetic; Quantitative Trait Loci; Systems Biology
TL;DR:
A new type of heterotic effect is defined denoted as augmented dominance effect di* that comprises the dominance effect at each QTL minus half the sum of additive × additive interactions with all other QTL.
(via Semantic Scholar)
www.genetics.org (publisher PDF)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
A semiparametric approach for composite functional mapping of dynamic quantitative traits
GENETICS, 177(3), 1859–1870.
MeSH headings : Algorithms; Chromosome Mapping / methods; Chromosome Mapping / statistics & numerical data; Likelihood Functions; Models, Genetic; Models, Statistical; Monte Carlo Method; Oryza / genetics; Oryza / growth & development; Polymorphism, Restriction Fragment Length; Quantitative Trait Loci; Regression Analysis
TL;DR:
A statistical framework for mapping QTL that affect dynamic traits by capitalizing on the strengths of functional mapping and composite interval mapping is presented, leading to the identification of multiple QTL, some of which are linked on the same chromosome, that control the developmental trajectory of leaf age.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Speed-mapping quantitative trait loci using microarrays
NATURE METHODS, 4(10), 839–841.
MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / growth & development; Female; Gene Expression Profiling / methods; Longevity / genetics; Male; Oligonucleotide Array Sequence Analysis / methods; Polymorphism, Genetic / genetics; Quantitative Trait Loci
TL;DR:
A rapid, economical method for high-resolution quantitative trait locus (QTL) mapping using microarrays for selective genotyping of pooled DNA samples is developed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Protein evolution constraints and model-based techniques to study them
CURRENT OPINION IN STRUCTURAL BIOLOGY, 17(3), 337–341.
MeSH headings : Evolution, Molecular; Models, Molecular; Protein Folding; Proteins / chemistry; Proteins / genetics
TL;DR:
Although statistical tools for characterizing protein evolution are improving, the list of candidate phenomena that can affect rates of protein evolution is long and the relative contributions of these phenomena are only beginning to be disentangled.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Non-monotonic dose-response relationship in steroid hormone receptor-mediated gene expression
JOURNAL OF MOLECULAR ENDOCRINOLOGY, 38(5-6), 569–585.
MeSH headings : Animals; Dimerization; Dose-Response Relationship, Drug; Gene Expression Regulation / drug effects; Hormones / pharmacology; Humans; Ligands; Models, Biological; Models, Theoretical; Receptors, Steroid / agonists; Receptors, Steroid / antagonists & inhibitors; Receptors, Steroid / genetics; Receptors, Steroid / metabolism; Repressor Proteins / metabolism; Repressor Proteins / pharmacology; Trans-Activators / metabolism; Trans-Activators / pharmacology
TL;DR:
This work provides a novel mechanism for non-monotonic, particularly U-shaped, dose-response behaviors observed with certain steroid mimics, and may help not only understand how selective steroid receptor modulators work but also improve risk assessment for EACs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Comprehensive transcriptome profiling in tomato reveals a role for glycosyltransferase in Mi-mediated nematode resistance
PLANT PHYSIOLOGY, 144(2), 1079–1092.
MeSH headings : Animals; Feeding Behavior / physiology; Gene Expression; Gene Expression Profiling; Gene Expression Regulation, Plant; Gene Silencing; Genomics; Glycosyltransferases / metabolism; Host-Parasite Interactions / physiology; Solanum lycopersicum / enzymology; Solanum lycopersicum / genetics; Solanum lycopersicum / parasitology; Oligonucleotide Array Sequence Analysis; Plant Roots / enzymology; Plant Roots / metabolism; Plant Roots / parasitology; Reproduction / physiology; Tylenchoidea / physiology
TL;DR:
The root transcriptome of the resistant and susceptible cultivars ‘Motelle’ and ‘Moneymaker’ is interrogated, providing a picture of global gene expression changes in roots during compatible and incompatible associations with RKN, and point to candidates for further investigation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Quantifying the impact of protein tertiary structure on molecular evolution
MOLECULAR BIOLOGY AND EVOLUTION, 24(8), 1769–1782.
author keywords: molecular evolution; protein structure impact; Gene Ontology; MCMC; Bayes factor
MeSH headings : Bayes Theorem; Computational Biology; Computer Simulation; Data Interpretation, Statistical; Evolution, Molecular; Protein Structure, Tertiary; Proteins / chemistry; Proteins / genetics; Sequence Alignment
TL;DR:
Although their influences on rates of evolution vary among protein families, it is found that the mean impacts of solvent accessibility and pairwise interactions are about the same.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Population genetics without intraspecific data
MOLECULAR BIOLOGY AND EVOLUTION, 24(8), 1667–1677.
author keywords: dependence among sites; fixation probability; protein structure; RNA structure
MeSH headings : Animals; Annexin A5 / genetics; Computational Biology; Computer Simulation; Evolution, Molecular; Genetic Variation; Genetics, Population; Likelihood Functions; Mice; Models, Biological; Models, Genetic; Nucleic Acid Conformation; Phenotype; Phylogeny; RNA / chemistry; RNA / genetics; Rats; Selection, Genetic
TL;DR:
It is argued that statistical fit to data should not be the sole criterion for assessing models of sequence change, and a good interspecific model should also yield a clear and biologically plausible population genetic interpretation.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
A tabu search algorithm for maximum parsimony phylogeny inference
EUROPEAN JOURNAL OF OPERATIONAL RESEARCH, 176(3), 1908–1917.
author keywords: tabu search; OR in biology; bioinformatics; phylogeny inference; maximum parsimony
TL;DR:
The parsimony principle is adopted and a tabu search algorithm is designed for finding a most parsimonious phylogeny tree and it generates much more accurate results than the default options of the program “dnapars” (heuristic search based).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
Genomic relationships and speciation times of human, chimpanzee, and gorilla inferred from a coalescent hidden Markov model
PLOS GENETICS, 3(2), 294–304.
MeSH headings : Animals; Base Sequence; Computer Simulation; Genetic Speciation; Genetics, Population; Genome, Human; Gorilla gorilla / genetics; Hominidae / genetics; Humans; Markov Chains; Models, Theoretical; Molecular Sequence Data; Pan troglodytes / genetics; Phylogeny; Sequence Homology, Nucleic Acid
TL;DR:
A hidden Markov model that incorporates genealogical variation and relates the model parameters to population genetics quantities such as speciation times and ancestral population sizes finds that the rate of transitions between different genealogies correlates well with the region-wide present-day human recombination rate, but does not correlate with the fine-scale recombination rates and recombination hot spots.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2007 journal article
eQTL Viewer: visualizing how sequence variation affects genome-wide transcription
BMC Bioinformatics, 8(7).
Source: NC State University Libraries
Added: August 6, 2018
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