Bioinformatics Research Center

Works Published in 2010

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Displaying all 9 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 report

Power, sample size and confidence interval for quantitative trait loci mapping on multiple traits

By: L. E Silva, S. Chang & Z. Zeng

Source: NC State University Libraries
Added: August 16, 2021

2010 journal article

Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics

Clinical Pharmacology & Therapeutics, 89(1), 97–104.

By: Y. Ji*, S. Hebbring*, H. Zhu n, G. Jenkins*, J. Biernacka*, K. Snyder*, M. Drews*, O. Fiehn* ...

MeSH headings : Biomarkers, Pharmacological / blood; Cell Line; Chromosomes, Human, Pair 9 / genetics; Citalopram / therapeutic use; DNA-Binding Proteins / metabolism; Depressive Disorder, Major / blood; Depressive Disorder, Major / drug therapy; Depressive Disorder, Major / genetics; Drug Monitoring / methods; Female; Genetic Association Studies; Glycine / blood; Glycine / metabolism; Glycine Dehydrogenase (Decarboxylating) / genetics; Humans; Introns / genetics; Linkage Disequilibrium; Male; Metabolome / drug effects; Nuclear Proteins / metabolism; Polymorphism, Single Nucleotide; Selective Serotonin Reuptake Inhibitors / therapeutic use
TL;DR: A possible role for glycine in SSRI response is highlighted and the use of pharmacometabolomics‐informed pharmacogenomic research strategy to identify citalopram/escitaloprams treatment outcome biomarkers is illustrated to “inform” pharmacogenomics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Crossref
Added: July 28, 2019

2010 journal article

Lipidomic analysis of variation in response to simvastatin in the Cholesterol and Pharmacogenetics Study

Metabolomics, 6(2), 191–201.

By: R. Kaddurah-Daouk*, R. Baillie*, H. Zhu n, Z. Zeng n, M. Wiest*, U. Nguyen*, S. Watkins*, R. Krauss

author keywords: Cardiovascular disease; Lipidomics; Metabolomics; Pharmacogenomics; Pharmacometabolomics; Simvastatin
TL;DR: There was no overlap of lipids whose changes correlated with LDL-C or CRP responses to simvastatin suggesting that distinct metabolic pathways govern statin effects on these two biomarkers. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

2010 review

Auriculotherapy for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

[Review of ]. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 16(10), 1097–1108.

By: G. Asher*, D. Jonas*, R. Coeytaux*, A. Reilly*, Y. Loh*, A. Motsinger-Reif n, S. Winham n

MeSH headings : Acupuncture, Ear; Analgesia; Humans; Pain Management; Pain Measurement; Perioperative Period; Randomized Controlled Trials as Topic
TL;DR: Auriculotherapy may be effective for the treatment of a variety of types of pain, especially postoperative pain, however, a more accurate estimate of the effect will require further large, well-designed trials. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Genomic hotspots for adaptation: The population genetics of Mullerian mimicry in Heliconius erato

PLoS Genetics, 6(4).

By: B. Counterman, F. Araujo-Perez, H. Hines, S. Baxter, C. Morrison, D. Lindstrom, R. Papa, L. Ferguson ...

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Current Progress on Statistical Methods for Mapping Quantitative Trait Loci from Inbred Line Crosses

JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 20(2), 454–481.

By: L. Silva n & Z. Zeng n

author keywords: Inbred lines; Quantitative trait loci; Statistical methods
MeSH headings : Algorithms; Animals; Animals, Inbred Strains; Bayes Theorem; Crosses, Genetic; Data Interpretation, Statistical; Genome-Wide Association Study / statistics & numerical data; Genotype; Likelihood Functions; Models, Statistical; Phenotype; Quantitative Trait Loci; Reproducibility of Results
TL;DR: The progress of research in this area on one trait and multiple traits by maximum likelihood and Bayesian methods is reviewed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

QTL Identification Using Combined Linkage and Linkage Disequilibrium Mapping for Milk Production Traits on BTA6 in Chinese Holstein Population

ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 23(10), 1261–1267.

By: F. Hu n, J. Liu*, Z. Zeng n, X. Ding*, C. Yin*, Y. Gong*, Q. Zhang*

author keywords: Fine Mapping; QTL; Bos Taurus autosome 6; Milk Production Traits
TL;DR: The aim of the present study was to refine the position of previously detected quantitative trait loci (QTL) on bovine chromosome 6 affecting milk production traits in Chinese Holstein dairy cattle. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

A comparison of internal validation techniques for multifactor dimensionality reduction

BMC Bioinformatics, 11.

By: S. Winham, A. Slater & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Polymorphisms in IL-1 beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

BMC Medical Genetics, 11.

By: A. Motsinger-Reif, P. Antas, N. Oki, S. Levy, S. Holland & T. Sterling

Source: NC State University Libraries
Added: August 6, 2018

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