Works Published in 2011
Displaying all 10 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2011 journal article
QTL Mapping for Days to Flowering under Drought Condition in Rice (Oryza sativa L.) Genome
Notulae Botanicae Horti Agrobotanici Cluj-Napoca, 39(1), 58.
TL;DR:
The five common QTL detected by at least two models could be considered as stable QTL for days to flowering under drought and might be of practical use in marker assisted selection.
(via Semantic Scholar)
www.notulaebotanicae.ro (publisher PDF)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: Crossref
Added: July 20, 2019
2011 journal article
Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment
PLOS ONE, 6(10).
MeSH headings : Bile Acids and Salts / metabolism; Cholesterol, LDL / blood; Demography; Female; Gastrointestinal Tract / drug effects; Gastrointestinal Tract / metabolism; Gastrointestinal Tract / microbiology; Humans; Liver-Specific Organic Anion Transporter 1; Male; Metabolomics; Metagenome / drug effects; Middle Aged; Models, Biological; Organic Anion Transporters / genetics; Pharmacogenetics; Polymorphism, Single Nucleotide / genetics; Simvastatin / pharmacology; Treatment Outcome
TL;DR:
Interactions between genome, gut microbiome and environmental influences should be considered in the study and management of cardiovascular disease and metabolic profiles could provide valuable information about treatment outcomes and could contribute to a more personalized approach to therapy.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Synthesizing and databasing fossil calibrations: divergence dating and beyond
Biology Letters, 7(6), 801–803.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
Coordinated Genome-Wide Modifications within Proximal Promoter Cis-regulatory Elements during Vertebrate Evolution
GENOME BIOLOGY AND EVOLUTION, 3, 66–74.
author keywords: gene expression; transcriptional regulation; protein-DNA coevolution; cis-regulatory evolution
MeSH headings : Animals; Evolution, Molecular; Gene Expression; Genome; Humans; Mice; Models, Genetic; Models, Statistical; Phylogeny; Promoter Regions, Genetic; Regulatory Sequences, Nucleic Acid; Transcriptional Activation; Vertebrates / genetics
TL;DR:
It is found that a surprisingly large number of cis-regulatory elements have been subject to coordinated genome-wide modifications during vertebrate evolution, such that the motif frequency changes on a single branch of vertebrate phylogeny.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
History Can Matter: Non-Markovian Behavior of Ancestral Lineages
SYSTEMATIC BIOLOGY, 60(3), 276–290.
author keywords: Ancestral lineage; ancestral process; Hill-Robertson effect; population genetics
MeSH headings : Computer Simulation; Evolution, Molecular; Genetic Fitness; Genetic Variation; Markov Chains; Models, Genetic; Polymorphism, Genetic; Selection, Genetic
TL;DR:
This work used the Wright-Fisher model of population genetics to simulate very many generations of mutation, natural selection, and genetic drift to show that the process by which a nonrecombining sequence changes over time can markedly deviate from the Markov assumption that is ubiquitous in molecular phylogenetics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Specific and modular binding code for cytosine recognition in pumilio/FBF (PUF) RNA-binding domains
Journal of Biological Chemistry, 286(30), 26732–26742.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
The Effect of Retrospective Sampling on Estimates of Prediction Error for Multifactor Dimensionality Reduction
Annals of Human Genetics, 75, 46–61.
Source: NC State University Libraries
Added: August 6, 2018
2011 journal article
High-Confidence Discovery of Genetic Network Regulators in Expression Quantitative Trait Loci Data
GENETICS, 187(3), 955–964.
MeSH headings : Algorithms; Bayes Theorem; Chromosome Mapping; Computational Biology; Computer Simulation; Gene Expression Profiling / statistics & numerical data; Gene Regulatory Networks; Genes, Regulator / genetics; Genetic Markers / genetics; Models, Genetic; Quantitative Trait Loci / genetics; Saccharomyces cerevisiae / genetics
TL;DR:
This work introduces the concept of “shielding” in which a specific gene expression variable (the shielder) renders a set of other gene expression variables (the shielded genes) independent of the eQTL, and proposes a novel test for controlling the shielder false-positive rate at a predetermined level by requiring a threshold number of shielded genes per shielder.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
A Comparison of Multifactor Dimensionality Reduction and L-1-Penalized Regression to Identify Gene-Gene Interactions in Genetic Association Studies
STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY, 10(1).
author keywords: Multifactor Dimensionality Reduction (MDR); Lasso; gene-gene interactions
MeSH headings : Algorithms; Computer Simulation; Data Mining / methods; Epistasis, Genetic; Genetic Association Studies / statistics & numerical data; Humans; Monte Carlo Method; Multifactor Dimensionality Reduction / methods
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
16. Peace, Justice and Strong Institutions
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2011 journal article
Glycine and a Glycine Dehydrogenase (GLDC) SNP as Citalopram/Escitalopram Response Biomarkers in Depression: Pharmacometabolomics-Informed Pharmacogenomics
CLINICAL PHARMACOLOGY & THERAPEUTICS, 89(1), 97–104.
MeSH headings : Biomarkers, Pharmacological / blood; Cell Line; Chromosomes, Human, Pair 9 / genetics; Citalopram / therapeutic use; DNA-Binding Proteins / metabolism; Depressive Disorder, Major / blood; Depressive Disorder, Major / drug therapy; Depressive Disorder, Major / genetics; Drug Monitoring / methods; Female; Genetic Association Studies; Glycine / blood; Glycine / metabolism; Glycine Dehydrogenase (Decarboxylating) / genetics; Humans; Introns / genetics; Linkage Disequilibrium; Male; Metabolome / drug effects; Nuclear Proteins / metabolism; Polymorphism, Single Nucleotide; Selective Serotonin Reuptake Inhibitors / therapeutic use
TL;DR:
A possible role for glycine in SSRI response is highlighted and the use of pharmacometabolomics‐informed pharmacogenomic research strategy to identify citalopram/escitaloprams treatment outcome biomarkers is illustrated to “inform” pharmacogenomics.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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