Bioinformatics Research Center

Works Published in 2019

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Displaying all 6 works

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2019 journal article

Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines


author keywords: synergy; heritability; chemotherapy; lymphoblastoid cell lines; linkage mapping
TL;DR: It is demonstrated that synergy occurs and can be quantified in LCLs across a range of clinically important drug combinations, which supports the premise of expanding the use of the LCL model to perform association mapping for combination therapies. (via Semantic Scholar)
Source: Web Of Science
Added: December 2, 2019

2019 journal article

Video-Based Driver's Hand Tracking using Fast Normalized Cross Coefficient with Improved Computational Efficiency


By: L. Li n, C. Hutmacher n & X. Xu n

TL;DR: A computer vision-based method to track hand movement from the recorded driving behavior using fast normalized cross coefficient (NCC) and a novel searching strategy is proposed, which outperformed a state of the art algorithm in MOTA and MT. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 14, 2019

2019 journal article

Genomic Selection with Allele Dosage in Panicum maximum Jacq.

G3-GENES GENOMES GENETICS, 9(8), 2463–2475.

author keywords: Plant Breeding; Guinea Grass; Quantitative Genotyping; Polyploidy; Genotyping-by-sequencing (GBS); Recurrent Genomic Selection; Genomic Prediction; GenPred; Shared Data Resources
MeSH headings : Algorithms; Alleles; Gene Dosage; Genome, Plant; Genomics / methods; Panicum / genetics; Phenotype; Plant Breeding; Polyploidy; Selection, Genetic
TL;DR: This work provides bioinformatic and modeling guidelines to consider tetraploid dosage and observed that genomic selection may lead to additional gains in recurrent selection program of P. maximum. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Source: Web Of Science
Added: August 26, 2019

2019 article

RiboStreamR: a web application for quality control, analysis, and visualization of Ribo-seq data

Perkins, P., Mazzoni-Putman, S., Stepanova, A., Alonso, J., & Heber, S. (2019, June 6). BMC GENOMICS, Vol. 20.

By: P. Perkins n, S. Mazzoni-Putman n, A. Stepanova n, J. Alonso n & S. Heber n

author keywords: Ribo-seq; Next-generation sequencing; Data analysis; Web application
MeSH headings : Computer Graphics; Genomics / methods; High-Throughput Nucleotide Sequencing / methods; Humans; Protein Biosynthesis; Quality Control; RNA, Messenger / genetics; RNA, Messenger / metabolism; Ribosomes / metabolism; Sequence Analysis, RNA; Software; Transcriptome; Web Browser
TL;DR: RiboStreamR is presented, a comprehensive Ribo-seq quality control (QC) platform in the form of an R Shiny web application that provides visualization and analysis tools for various Ribe-seq QC metrics, including read length distribution, read periodicity, and translational efficiency. (via Semantic Scholar)
Source: Web Of Science
Added: July 1, 2019

2019 article

Applications of CRISPR Technologies Across the Food Supply Chain


By: K. Brandt n & R. Barrangou n

author keywords: CRISPR-Cas; genome editing; crop development; food supply chain; livestock
MeSH headings : Animals; Clustered Regularly Interspaced Short Palindromic Repeats; Crops, Agricultural / genetics; Food Supply; Gene Editing; Livestock
TL;DR: The concept of applying CRISPR-Cas technology as a genome-editing tool for use in the food supply chain is introduced, focusing on its implementation to date in crop, livestock, and microbe production, advancement of products to market, and regulatory and societal hurdles that need to be overcome. (via Semantic Scholar)
Source: Web Of Science
Added: April 22, 2019

2019 journal article

Assessment of the non-lactic acid bacteria microbiota in fresh cucumbers and commercially fermented cucumber pickles brined with 6% NaCl


By: I. Perez-Diaz n, J. Hayes n, E. Medina n, A. Webber n, N. Butz*, A. Dickey n, Z. Lu*, M. Azcarate-Peril*

author keywords: Aerobic bacteria; Gram-negative; Cucumber fermentation; Microbiome
MeSH headings : Bacteria / classification; Bacteria / genetics; Bacteria / isolation & purification; Cucumis sativus / microbiology; DNA, Bacterial; Fermentation; Fermented Foods / microbiology; Food Microbiology; Hydrogen-Ion Concentration; Microbiota; Oxygen / analysis; RNA, Ribosomal, 16S / genetics; Salts; Sodium Chloride / metabolism
TL;DR: Whether the low relative abundance of non-LAB in commercial cucumber fermentations, in particular Pseudomonas and Enterobacteriaceae, impacts the quality of fermented cucumbers is elucidated. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: October 19, 2018

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