Bioinformatics

Works Published in 2010

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Displaying works 21 - 35 of 35 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Canopy and litter ant assemblages share similar climate-species density relationships

BIOLOGY LETTERS, 6(6), 769–772.

By: M. Weiser n, N. Sanders *, D. Agosti, A. Andersen *, A. Ellison *, B. Fisher *, H. Gibb *, N. Gotelli * ...

author keywords: Formicidae; species richness; global diversity gradients
MeSH headings : Animals; Ants / physiology; Ecosystem; Linear Models; Models, Biological; Population Density; Species Specificity; Trees; Tropical Climate; Weather
TL;DR: It appears that canopy and litter ant assemblages share a common abundance–diversity relationship influenced by similar but not identical climatic drivers. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (OpenAlex)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Genome-wide sssociation dtudy of Lp-PLA(2) sctivity and mass in the Framingham Heart Study

PLoS Genetics, 6(4).

By: S. Suchindran, D. Rivedal, J. Guyton, T. Milledge, X. Gao, A. Benjamin, J. Rowell, G. Ginsburg, J. McCarthy

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Warfarin pharmacogenetics: a single VKORC1 polymorphism is predictive of dose across 3 racial groups

BLOOD, 115(18), 3827–3834.

By: N. Limdi *, M. Wadelius *, L. Cavallari *, N. Eriksson, D. Crawford *, M. Lee *, C. Chen*, A. Motsinger-Reif n ...

MeSH headings : Adult; Aged; Aged, 80 and over; Algorithms; Anticoagulants / administration & dosage; Asian People / genetics; Black People / genetics; Dose-Response Relationship, Drug; Female; Genotype; Haplotypes; Humans; Linkage Disequilibrium; Male; Middle Aged; Mixed Function Oxygenases / genetics; Pharmacogenetics; Polymorphism, Single Nucleotide / genetics; Racial Groups / genetics; Risk Factors; Vitamin K Epoxide Reductases; Warfarin / administration & dosage; White People / genetics
TL;DR: Clinicians should recognize that, although at a population level, the contribution of VKORC1 toward dose requirements is higher in whites than in nonwhites; genotype predicts similar dose requirements across racial groups. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 conference paper

Grammatical evolution decision trees for detecting gene-gene interactions

Evolutionary computation, machine learning and data mining in bioinformatics, proceedings, 6023, 98–109.

By: S. Deodhar & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Plant geography upon the basis of functional traits: An example from eastern North American trees

Ecology (Brooklyn, New York, N.Y.), 91(8), 2234–2241.

By: N. Swenson & M. Weiser

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

A quality control algorithm for filtering SNPs in genome-wide association studies

BIOINFORMATICS, 26(14), 1731–1737.

By: M. Pongpanich n, P. Sullivan  n & J. Tzeng n

MeSH headings : Algorithms; Genome; Genome-Wide Association Study / methods; Genome-Wide Association Study / standards; Polymorphism, Single Nucleotide; Quality Control
TL;DR: An algorithm that is based on principal component analysis and clustering analysis to identify low-quality SNPs and suggests that with the same or fewer SNPs excluded, the proposed algorithm tends to give a similar or lower value of lambda, a reduced number of false associations, and retains all true associations. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Proteomic and Bioinformatic Analysis of the Root-Knot Nematode Meloidogyne hapla: The Basis for Plant Parasitism

JOURNAL OF PROTEOME RESEARCH, 9(10), 5370–5381.

By: F. Mbeunkui n, E. Scholl n, C. Opperman  n, M. Goshe n & D. Bird n 

Contributors: F. Mbeunkui n, E. Scholl n, C. Opperman  n, M. Goshe n & D. Bird n 

author keywords: LC/MSE; plant-parasite; nematode; data-independent acquisition; computational proteome
MeSH headings : Animals; Chromatography, Liquid; Computational Biology / methods; Databases, Protein; Genome, Helminth / genetics; Helminth Proteins / genetics; Helminth Proteins / metabolism; Humans; Internet; Plant Roots / parasitology; Proteomics / methods; Tandem Mass Spectrometry; Tylenchoidea / genetics; Tylenchoidea / metabolism
TL;DR: To experimentally confirm the HapPep3 assignments using proteomics, a data-independent LC/MS(E) analysis to M. hapla protein extracts fractionated by SDS-PAGE was applied, and it was concluded that the identified proteins reflect a true and unbiased sampling of Happep3. (via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land (OpenAlex)
Sources: Web Of Science, ORCID, NC State University Libraries
Added: August 6, 2018

2010 journal article

Direct measure of the de novo mutation rate in autism and schizophrenia cohorts

American Journal of Human Genetics, 87(3), 316–324.

By: P. Awadalla, J. Gauthier, R. Myers, F. Casals, F. Hamdan, A. Griffing, M. Cote, E. Henrion ...

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

More individuals but fewer species: testing the 'more individuals hypothesis' in a diverse tropical fauna

BIOLOGY LETTERS, 6(4), 490–493.

By: T. McGlynn*, M. Weiser n & R. Dunn n 

author keywords: ants; competition; diversity; leaf litter
MeSH headings : Animals; Ants / physiology; Biodiversity; Costa Rica; Ecosystem; Models, Theoretical; Population Density; Population Dynamics; Species Specificity; Tropical Climate
TL;DR: While large-scale correlations between ant diversity and net primary productivity or temperature are reconcilable with the MIH, key elements of the hypothesis are not supported. (via Semantic Scholar)
UN Sustainable Development Goal Categories
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Effect of CYP2B6, ABCB1, and CYP3A5 Polymorphisms on Efavirenz Pharmacokinetics and Treatment Response: An AIDS Clinical Trials Group Study

JOURNAL OF INFECTIOUS DISEASES, 202(5), 717–722.

By: H. Ribaudo *, H. Liu *, M. Schwab *, E. Schaeffeler*, M. Eichelbaum*, A. Motsinger-Reif n, M. Ritchie *, U. Zanger* ...

MeSH headings : ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1 / genetics; Alkynes; Anti-HIV Agents / pharmacokinetics; Anti-HIV Agents / therapeutic use; Aryl Hydrocarbon Hydroxylases / genetics; Benzoxazines / pharmacokinetics; Benzoxazines / therapeutic use; Black People; Cyclopropanes; Cytochrome P-450 CYP2B6; Cytochrome P-450 CYP3A / genetics; Female; HIV Infections / drug therapy; HIV Infections / ethnology; HIV Infections / genetics; Hispanic or Latino; Humans; Male; Oxidoreductases, N-Demethylating / genetics; Pharmacogenetics; Polymorphism, Single Nucleotide; Reverse Transcriptase Inhibitors / pharmacokinetics; Reverse Transcriptase Inhibitors / therapeutic use; Treatment Outcome; White People
TL;DR: Slow-metabolizer genotypes were associated with increased central nervous system events among white participants and decreased virologic failure among black participants and models that included CYP2B6 516/983 genotype best predicted pharmacokinetics. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2010 journal article

A comparison of internal validation techniques for multifactor dimensionality reduction

BMC Bioinformatics, 11.

By: S. Winham, A. Slater & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Rare Variants Create Synthetic Genome-Wide Associations

PLoS Biology, 8(1).

By: S. Dickson, K. Wang, I. Krantz, H. Hakonarson & D. Goldstein

Source: NC State University Libraries
Added: August 6, 2018

2010 journal article

Detection of alternative splice variants at the proteome level in Aspergillus flavus

Journal of Proteome Research, 9(3), 1209–1217.

By: K. Chang, D. Georgianna, S. Heber, G. Payne & D. Muddiman

Source: NC State University Libraries
Added: August 6, 2018

2010 article

Discussion of a Genome-Wide Association Approach to Determine HIV-1 Set Point in African Americans

Motsinger-Reif, A. A. (2010, April 15). JOURNAL OF INFECTIOUS DISEASES, Vol. 201, pp. 1118–1120.

By: A. Motsinger-Reif n

MeSH headings : Black or African American / genetics; Disease Susceptibility; Epitopes / genetics; Genome-Wide Association Study; HIV Infections / genetics; HIV-1; Humans; Polymorphism, Single Nucleotide / genetics
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2010 journal article

Polymorphisms in IL-1 beta, vitamin D receptor Fok1, and Toll-like receptor 2 are associated with extrapulmonary tuberculosis

BMC Medical Genetics, 11.

By: A. Motsinger-Reif, P. Antas, N. Oki, S. Levy, S. Holland & T. Sterling

Source: NC State University Libraries
Added: August 6, 2018

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