Bioinformatics

Works Published in 2011

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Displaying works 41 - 46 of 46 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2011 journal article

Identification and replication of loci involved in camptothecin-induced cytotoxicity using CEPH pedigrees

PLoS One, 6(5).

By: V. Watson, A. Motsinger-Reif, N. Hardison, E. Peters, T. Havener, L. Everitt, J. Auman, D. Comins, H. McLeod

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

The Effect of Retrospective Sampling on Estimates of Prediction Error for Multifactor Dimensionality Reduction

Annals of Human Genetics, 75, 46–61.

By: S. Winham & A. Motsinger-Reif

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

Transcriptional profiling of human placentas from pregnancies complicated by preeclampsia reveals disregulation of sialic acid acetylesterase and immune signalling pathways

PLACENTA, 32(2), 175–182.

By: S. Tsai n, N. Hardison n, A. James *, A. Motsinger-Reif n, S. Bischoff n, B. Thames*, J. Piedrahita n

author keywords: Placenta; Preeclampsia; Maternal hypertension; Sialic acid acetylesterase
MeSH headings : Acetylesterase / biosynthesis; Antigens, CD / biosynthesis; Endoglin; Female; Genome-Wide Association Study; Humans; Infant, Newborn; Inhibins / biosynthesis; Male; Pre-Eclampsia / etiology; Pre-Eclampsia / metabolism; Pregnancy; Protein Array Analysis; Receptors, Cell Surface / biosynthesis; Trophoblasts / physiology; Up-Regulation; Vascular Endothelial Growth Factor Receptor-1 / biosynthesis
TL;DR: Evidence is found of preeclampsia-associated placental upregulation of sialic acid acetylesterase (SIAE), a gene functionally associated with autoimmune diseases, and changes in immune-associated signaling pathways, offering a potential upstream explanation for the shallow trophoblast invasion and inadequate uterine remodeling typically observed in pathogenesis of preeClampsia. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
5. Gender Equality (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2011 article

Computational and phylogenetic validation of nematode horizontal gene transfer

Scholl, E. H., & Bird, D. M. K. (2011, February 22). BMC BIOLOGY, Vol. 9.

By: E. Scholl n & D. Bird n 

Contributors: E. Scholl n & D. Bird n 

MeSH headings : Animals; Cellulase / genetics; Evolution, Molecular; Gene Transfer, Horizontal; Genes, Helminth; Molecular Sequence Data; Nematoda / classification; Nematoda / genetics; Phylogeny
TL;DR: A detailed phylogenetic analysis of cellulase genes in the free-living nematode Pristionchus pacificus at the species, genus and family levels substantiates the hypothesis that such transfer has been a driving force in the evolution of niche specificity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2011 journal article

A population genetic approach to mapping neurological disorder genes using deep resequencing

PLoS Genetics, 7(2).

By: R. Myers, F. Casals, J. Gauthier, F. Hamdan, J. Keebler, A. Boyko, C. Bustamante, A. Piton ...

Source: NC State University Libraries
Added: August 6, 2018

2011 journal article

A Comparison of Multifactor Dimensionality Reduction and L-1-Penalized Regression to Identify Gene-Gene Interactions in Genetic Association Studies

STATISTICAL APPLICATIONS IN GENETICS AND MOLECULAR BIOLOGY, 10(1).

By: S. Winham n, C. Wang  n & A. Motsinger-Reif n

author keywords: Multifactor Dimensionality Reduction (MDR); Lasso; gene-gene interactions
MeSH headings : Algorithms; Computer Simulation; Data Mining / methods; Epistasis, Genetic; Genetic Association Studies / statistics & numerical data; Humans; Monte Carlo Method; Multifactor Dimensionality Reduction / methods
UN Sustainable Development Goal Categories
16. Peace, Justice and Strong Institutions (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

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