Works Published in 2005
Displaying all 20 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2005 chapter
Can Neural Network Constraints in GP Provide Power to Detect Genes Associated with Human Disease?
In F. Rothlauf (Ed.), Applications of Evolutionary Computing. EvoWorkshops 2005 (pp. 44–53).
Ed(s): F. Rothlauf
TL;DR:
It is demonstrated that using NN evolved by GP can be more powerful than GP alone to detect genetic effects in studies of the genetics of common, complex human disease.
(via Semantic Scholar)
Source: Crossref
Added: October 29, 2021
2005 journal article
Measures of human population structure show heterogeneity among genomic regions
Genome Research, 15(11), 1468–1476.
MeSH headings : Chromosomes, Human / genetics; Ethnicity / genetics; Genetic Heterogeneity; Genetics, Population; Genome, Human / genetics; Genomics / methods; Haplotypes / genetics; Humans; Linkage Disequilibrium / genetics; Polymorphism, Single Nucleotide / genetics; United States
TL;DR:
Estimates of genetic population structure (F(ST) were constructed from all autosomes in two large SNP data sets, and it is shown that individual-marker estimates are too variable to be useful.
(via Semantic Scholar)
genome.cshlp.org (publisher PDF)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Crossref
Added: March 5, 2021
2005 journal article
Measures of human population structure show heterogeneity among genomic regions
Genome Res, 15(11), 1468–1476.
Source: ORCID
Added: January 25, 2021
2005 journal article
Association of genetic polymorphisms with risk of renal injury after coronary bypass graft surgery
American Journal of Kidney Diseases, 45(3), 519–530.
author keywords: acute renal failure (ARF); polymorphism; genetic; postoperative; intensive care; cardiopulmonary bypass (CPB); heart surgery; cardiac surgery; human; angiotensin-converting enzyme (ACE); associate study; candidate genes
MeSH headings : Acute Kidney Injury / blood; Acute Kidney Injury / epidemiology; Acute Kidney Injury / ethnology; Acute Kidney Injury / genetics; Black or African American / genetics; Aged; Alleles; Angiotensins / genetics; Apolipoproteins E / genetics; Cardiovascular Diseases / epidemiology; Cardiovascular Diseases / surgery; Coronary Artery Bypass; Creatinine / blood; Cytokines / genetics; DNA Mutational Analysis; Female; Follow-Up Studies; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Nitric Oxide Synthase / genetics; Nitric Oxide Synthase Type III; North Carolina / epidemiology; Polymorphism, Genetic; Postoperative Complications / epidemiology; Prospective Studies; Pulmonary Disease, Chronic Obstructive / epidemiology; Receptor, Angiotensin, Type 1 / genetics; Risk; White People / genetics
TL;DR:
It is identified that genetic polymorphisms that collectively provide 2- to 4-fold improvement over preoperative clinical factors alone in explaining post-cardiac surgery renal dysfunction are associated with increased renal inflammatory and/or vasoconstrictor responses.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: September 5, 2020
2005 journal article
Genetic Polymorphisms and the Risk of Stroke After Cardiac Surgery
Stroke, 36(9), 1854–1858.
author keywords: cardiac surgical procedures; C-reactive protein; interleukin-6; polymorphism; stroke
MeSH headings : Aged; Alleles; C-Reactive Protein / genetics; Cardiopulmonary Bypass; Female; Genetic Predisposition to Disease; Genetic Variation; Humans; Inflammation; Interleukin-6 / genetics; Male; Middle Aged; Models, Genetic; Multivariate Analysis; Mutation; Odds Ratio; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Postoperative Complications; Risk; Sex Factors; Stroke / genetics; Thoracic Surgery
TL;DR:
It is demonstrated that common genetic variants of CRP (3′UTR 1846C/T) and IL-6 (−174G/C) are significantly associated with the risk of stroke after cardiac surgery, suggesting a pivotal role of inflammation in post–cardiac surgery stroke.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Sources: Crossref, ORCID
Added: September 5, 2020
2005 journal article
Substructural fragments: an universal language to encode reactions, molecular and supramolecular structures
Journal of Computer-Aided Molecular Design, 19(9-10), 693–703.
author keywords: chemical reactions; clustering; condensed graphs of reactions; exchange of information; hydrogen bonds; QSPR; similarity; solubility; substructural fragments
MeSH headings : Computer Simulation; Hydrogen Bonding; Macromolecular Substances; Models, Chemical; Molecular Structure; Quantitative Structure-Activity Relationship; Solubility; Thermodynamics; Water
TL;DR:
Substructural fragments are proposed as a simple and safe way to encode molecular structures in a matrix containing the occurrence of fragments of a given type and the knowledge retrieved from QSPR modelling can also be stored in that matrix in addition to the information about fragments.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Genetic Modifiers of Lung Disease in Cystic Fibrosis
New England Journal of Medicine, 353(14), 1443–1453.
MeSH headings : Adolescent; Adult; Child; Cystic Fibrosis / classification; Cystic Fibrosis / genetics; Cystic Fibrosis Transmembrane Conductance Regulator / genetics; DNA Replication; Female; Forced Expiratory Volume; Genotype; Humans; Linkage Disequilibrium; Logistic Models; Lung Diseases / classification; Lung Diseases / genetics; Lung Diseases / physiopathology; Male; Middle Aged; Phenotype; Polymorphism, Genetic; Severity of Illness Index; Transforming Growth Factor beta / genetics
TL;DR:
Genetic variation in the 5' end of TGFbeta1 or a nearby upstream region modifies disease severity in cystic fibrosis.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Crossref
Added: August 28, 2020
2005 journal article
Group A Streptococcus Transcriptome Dynamics during Growth in Human Blood Reveals Bacterial Adaptive and Survival Strategies
The American Journal of Pathology, 166(2), 455–465.
MeSH headings : DNA, Complementary / metabolism; Female; Flow Cytometry; Gene Expression Regulation, Bacterial; Humans; Male; Models, Biological; Mutation; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; RNA / metabolism; RNA, Messenger / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Streptococcal Infections / blood; Streptococcal Infections / metabolism; Streptococcus / metabolism; Time Factors
TL;DR:
Investigation of the transcriptome of a wild-type serotype M1 GAS strain in human blood reinforced the hypothesis that CovR-CovS has an important role linking key biosynthetic, catabolic, and virulence functions during transcriptome restructuring.
(via Semantic Scholar)
Source: Crossref
Added: August 28, 2020
2005 journal article
Nematode gene sequences: Update for December 2005
Journal of Nematology, 37(4), 417–421. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744980477&partnerID=MN8TOARS
Contributors: J. McCarter, D. Bird & M. Mitreva
Source: ORCID
Added: January 30, 2020
2005 journal article
A white paper on nematode comparative genomics
Journal of Nematology, 37(4), 408–416. http://www.scopus.com/inward/record.url?eid=2-s2.0-33744994353&partnerID=MN8TOARS
Contributors: D. Bird, M. Blaxter, J. McCarter, M. Mitreva, P. Sternberg & W. Thomas
Source: ORCID
Added: January 30, 2020
2005 journal article
The effect of bioactive glass ceramics on the expression of bone-related genes and proteins in vitro.
Clinical Oral Implants Research, 16(1), 119–127.
author keywords: bone-substitutes; cell-biomaterial interactions; glass ceramics; human bone-derived cells; in situ hybridization
MeSH headings : Absorbable Implants; Adolescent; Alkaline Phosphatase / biosynthesis; Bone Substitutes / pharmacology; Bone and Bones / cytology; Bone and Bones / drug effects; Bone and Bones / metabolism; Calcium Phosphates / pharmacology; Cell Differentiation / drug effects; Cell Proliferation / drug effects; Cells, Cultured; Ceramics / pharmacology; Collagen Type I / biosynthesis; Female; Gene Expression; Humans; In Situ Hybridization; Integrin-Binding Sialoprotein; Osteoblasts / drug effects; Osteoblasts / metabolism; Osteocalcin / biosynthesis; Osteonectin / biosynthesis; Osteopontin; RNA, Messenger / analysis; Sialoglycoproteins / biosynthesis
TL;DR:
GB9N had the most effect on osteoblastic differentiation, thus suggesting that this material may possess a higher potency to enhance osteogenesis than TCP.
(via Semantic Scholar)
Source: ORCID
Added: May 14, 2019
2005 journal article
Exploratory visual analysis of pharmacogenomic results.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing. http://europepmc.org/abstract/med/15759635
Source: ORCID
Added: May 14, 2019
2005 conference paper
Exploratory visual analysis of pharmacogenomic results
Proceedings of the Pacific Symposium on Biocomputing 2005, PSB 2005, 296–307. http://www.scopus.com/inward/record.url?eid=2-s2.0-15944408038&partnerID=MN8TOARS
Contributors: D. Reif , S. Dudek, C. Shaffer, J. Wang & J. Moore
Source: ORCID
Added: May 14, 2019
2005 conference paper
A statistical comparison of grammatical evolution strategies in the domain of human genetics
2005 IEEE Congress on Evolutionary Computation, IEEE CEC 2005. Proceedings, 1, 676–682. http://www.scopus.com/inward/record.url?eid=2-s2.0-27144535907&partnerID=MN8TOARS
Contributors: B. White, J. Gilbert, D. Reif & J. Moore
Source: ORCID
Added: May 14, 2019
2005 journal article
Combinatorial Pharmacogenetics
Nat Rev Drug Discov, 4(11), 911â918.
Contributors: R. Wilke*, D. Reif* & J. Moore
MeSH headings : Animals; Cytochrome P-450 Enzyme System / genetics; Drug-Related Side Effects and Adverse Reactions / enzymology; Drug-Related Side Effects and Adverse Reactions / genetics; Humans; Inactivation, Metabolic; Pharmaceutical Preparations / metabolism; Pharmacogenetics; Polymorphism, Genetic; Risk
TL;DR:
The relatively high concordance between polymorphisms in drug-metabolizing enzymes and clinical phenotypes indicates that research into this class of polymorphisms could benefit patients in the near future.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: May 14, 2019
2005 journal article
Resolving tylenchid evolutionary relationships through multiple gene analysis derived from EST data
MOLECULAR PHYLOGENETICS AND EVOLUTION, 36(3), 536–545.
author keywords: Bayesian; Caenorhabditis elegans; COG; cyst nematode; orthologues; root-knot nematode
MeSH headings : Animals; Evolution, Molecular; Expressed Sequence Tags; Phylogeny; Selection, Genetic; Tylenchida / genetics
TL;DR:
This EST-based multi-gene analysis is a first step towards accomplishing genome-wide coverage for tylenchid evolutionary analyses and reveals significant differences in selective pressure for some genes under some hypotheses, though all but one gene are exclusively under purifying selection.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: August 6, 2018
2005 journal article
Model systems in agriculture: Lessons from worms
Annals of Applied Biology, 146(2), 147–154.
Contributors: D. Bird n
TL;DR:
Genomic tools are expanding the utility of organisms originally developed as models for biomedical research as a means to address complex agricultural problems, and agricultural pests are serving as models to help unravel questions of basic biology.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018
2005 journal article
Root-knot nematodes and bacterial Nod factors elicit common signal transduction events in Lotus japonicus
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 102(8), 3147–3152.
Contributors: R. Weerasinghe n, D. Bird n & N. Allen n
author keywords: cytoskeleton; NemF; rhizobia; actin; microtubule
MeSH headings : Animals; Cytoskeleton / physiology; Lipopolysaccharides / pharmacology; Lotus / physiology; Signal Transduction / physiology; Symbiosis; Tylenchoidea / physiology
TL;DR:
It is proposed that plant-parasitic root-knot nematodes have adapted at least part of the symbiont-response pathway to enhance their parasitic ability.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2005 journal article
Phylogenetic analysis of Pasteuria penetrans by use of multiple genetic loci
JOURNAL OF BACTERIOLOGY, 187(16), 5700–5708.
Contributors: L. Charles n, I. Carbone n , K. Davies *, D. Bird n , M. Burke n, B. Kerry*, C. Opperman n
MeSH headings : Animals; Bacillus / genetics; Bacterial Proteins / genetics; Bayes Theorem; Models, Genetic; Phylogeny; Tylenchoidea / microbiology
TL;DR:
It is suggested that P. penetrans may have evolved from an ancient symbiotic bacterial associate of nematodes, possibly as the root knot nematode evolved to be a highly specialized parasite of plants.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
2005 review
Comparative genomics of nematodes
[Review of ]. TRENDS IN GENETICS, 21(10), 573–581.
Contributors: M. Mitreva *, M. Blaxter *, D. Bird n & J. McCarter*
MeSH headings : Animals; Chromosome Aberrations; Databases, Genetic; Evolution, Molecular; Gene Transfer, Horizontal / genetics; Genetic Variation; Genome / genetics; Genomics / methods; Genomics / trends; Nematoda / genetics; Phylogeny; Species Specificity
TL;DR:
Analysis of draft nematode genome sequences have revealed multiple unexpected results, which will underpin both molecular understanding of these most abundant metazoan organisms and aid in the examination of the dynamics of genome evolution in animals.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018
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