Works Published in 2010

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Displaying works 1 - 20 of 35 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2010 journal article

Modeling Liver-Related Adverse Effects of Drugs UsingkNearest Neighbor Quantitative Structure−Activity Relationship Method

Chemical Research in Toxicology, 23(4), 724–732.

co-author countries: United States of America 🇺🇸
MeSH headings : Algorithms; Chemical and Drug Induced Liver Injury / etiology; Databases, Factual; Drug-Related Side Effects and Adverse Reactions; Humans; Models, Biological; Models, Molecular; Quantitative Structure-Activity Relationship
Source: Crossref
Added: January 24, 2021

2010 journal article

Genomic Hotspots for Adaptation: The Population Genetics of Müllerian Mimicry in Heliconius erato

PLoS Genetics, 6(2), e1000796.

By: B. Counterman n, F. Araujo-Perez*, H. Hines n, S. Baxter*, C. Morrison*, D. Lindstrom n, R. Papa*, L. Ferguson* ...

co-author countries: France 🇫🇷 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Puerto Rico 🇵🇷 United States of America 🇺🇸

Ed(s): M. Nachman

MeSH headings : Adaptation, Physiological / genetics; Animals; Butterflies / genetics; Chromosomes, Artificial, Bacterial / genetics; Gene Expression Regulation; Genetic Loci / genetics; Genetic Variation; Genetics, Population; Genome / genetics; Genotype; Hybridization, Genetic; Linkage Disequilibrium / genetics; Open Reading Frames / genetics; Peru; Phenotype; Physical Chromosome Mapping; Pigmentation / genetics; Polymorphism, Single Nucleotide / genetics; Sequence Analysis, DNA
Sources: Crossref, ORCID
Added: September 5, 2020

2010 journal article

Cheminformatics Analysis of Assertions Mined from Literature That Describe Drug-Induced Liver Injury in Different Species

Chemical Research in Toxicology, 23(1), 171–183.

By: D. Fourches*, J. Barnes*, N. Day*, P. Bradley*, J. Reed* & A. Tropsha*

co-author countries: United States of America 🇺🇸
MeSH headings : Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship
Source: Crossref
Added: August 28, 2020

2010 journal article

Quantitative Nanostructure−Activity Relationship Modeling

ACS Nano, 4(10), 5703–5712.

By: D. Fourches*, D. Pu*, C. Tassa*, R. Weissleder*, S. Shaw*, R. Mumper*, A. Tropsha*

co-author countries: United States of America 🇺🇸
author keywords: nanoparticles; QSAR; cheminformatics; nanotoxicity; modeling
MeSH headings : Animals; Cell Line, Tumor; Humans; Metal Nanoparticles / chemistry; Microscopy, Atomic Force / methods; Models, Statistical; Models, Theoretical; Nanotechnology / methods; Oxides / chemistry; Quantitative Structure-Activity Relationship; Rats; Regression Analysis; Surface Properties; U937 Cells
Source: Crossref
Added: August 28, 2020

2010 journal article

Applicability Domains for Classification Problems: Benchmarking of Distance to Models for Ames Mutagenicity Set

Journal of Chemical Information and Modeling, 50(12), 2094–2111.

By: I. Sushko*, S. Novotarskyi*, R. Körner*, A. Pandey*, A. Cherkasov*, J. Li*, P. Gramatica*, K. Hansen* ...

co-author countries: Canada 🇨🇦 Germany 🇩🇪 Italy 🇮🇹
MeSH headings : Benchmarking / methods; Classification / methods; Mutagenicity Tests / methods; Mutagenicity Tests / standards; Principal Component Analysis; Quantitative Structure-Activity Relationship
Source: Crossref
Added: August 28, 2020

2010 journal article

Trust, But Verify: On the Importance of Chemical Structure Curation in Cheminformatics and QSAR Modeling Research

Journal of Chemical Information and Modeling, 50(7), 1189–1204.

By: D. Fourches*, E. Muratov & A. Tropsha

MeSH headings : Animals; Models, Chemical; Molecular Structure; Organometallic Compounds / chemistry; Quantitative Structure-Activity Relationship
Source: Crossref
Added: August 28, 2020

2010 journal article

Interactome analysis of longitudinal pharyngeal infection of cynomolgus macaques by group A Streptococcus

Proceedings of the National Academy of Sciences, 107(10), 4693–4698.

By: P. Shea*, K. Virtaneva*, J. Kupko*, S. Porcella*, W. Barry*, F. Wright*, S. Kobayashi, A. Carmody* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
author keywords: epithelial growth factor receptor; host pathogen; microarray; Streptococcus pyogenes; transcriptome
MeSH headings : Animals; Bacterial Proteins / genetics; Bacterial Proteins / metabolism; Clathrin-Coated Vesicles / metabolism; Cytokines / metabolism; GTP Phosphohydrolases / genetics; GTP Phosphohydrolases / metabolism; Gene Expression Profiling; Host-Pathogen Interactions; Hyaluronic Acid / metabolism; Macaca fascicularis / genetics; Macaca fascicularis / metabolism; Macaca fascicularis / microbiology; Neutrophils / metabolism; Neutrophils / microbiology; Neutrophils / pathology; Oligonucleotide Array Sequence Analysis; Pharyngitis / genetics; Pharyngitis / microbiology; Pharynx / metabolism; Pharynx / microbiology; Pharynx / pathology; Reverse Transcriptase Polymerase Chain Reaction; Streptococcus pyogenes / genetics; Streptococcus pyogenes / metabolism; Streptococcus pyogenes / physiology
Source: Crossref
Added: August 28, 2020

2010 journal article

Use of Pharmaco-Metabonomics for Early Prediction of Acetaminophen-Induced Hepatotoxicity in Humans

Clinical Pharmacology & Therapeutics, 88(1), 45–51.

By: J. Winnike*, Z. Li*, F. Wright*, J. Macdonald*, T. O'Connell* & P. Watkins*

co-author countries: United States of America 🇺🇸
MeSH headings : Acetaminophen / adverse effects; Acetaminophen / metabolism; Acetaminophen / pharmacology; Adolescent; Adult; Alanine Transaminase / blood; Analgesics, Non-Narcotic / adverse effects; Analgesics, Non-Narcotic / metabolism; Analgesics, Non-Narcotic / pharmacology; Biotransformation; Chemical and Drug Induced Liver Injury / diagnosis; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / urine; Cohort Studies; Data Interpretation, Statistical; Female; Humans; Least-Squares Analysis; Liver Function Tests; Magnetic Resonance Spectroscopy; Male; Middle Aged; Multivariate Analysis; Predictive Value of Tests; Young Adult
Source: Crossref
Added: August 28, 2020

2010 journal article

An approximate Bayesian approach for quantitative trait loci estimation

Computational Statistics & Data Analysis, 54(2), 565–574.

By: Y. Chang*, F. Zou* & F. Wright*

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: August 28, 2020

2010 chapter

Grammatical Evolution Decision Trees for Detecting Gene-Gene Interactions

In Evolutionary Computation, Machine Learning and Data Mining in Bioinformatics (pp. 98–109).

By: S. Deodhar n & A. Motsinger-Reif n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2010 journal article

In vitro screening of environmental chemicals for targeted testing prioritization: The toxcast project

Environmental Health Perspectives, 118(4), 485–492.

By: R. Judson*, K. Houck*, R. Kavlock*, T. Knudsen*, M. Martin*, H. Mortensen*, D. Reif*, D. Rotroff* ...

co-author countries: United States of America 🇺🇸

Contributors: R. Judson*, K. Houck*, R. Kavlock*, T. Knudsen*, M. Martin*, H. Mortensen*, D. Reif*, D. Rotroff* ...

author keywords: in vitro screening; liver proliferative lesions; liver tumors; pathways; ToxCast
MeSH headings : Animals; Cell Line; Cells, Cultured; Computer Simulation; Environmental Pollutants / toxicity; Humans; Rats; Toxicity Tests / methods; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2010 journal article

Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals.

Journal of Toxicology and Environmental Health - Part B: Critical Reviews, 13(2-4), 329–346.

By: D. Rotroff*, A. Beam, D. Dix*, A. Farmer, K. Freeman, K. Houck*, R. Judson*, E. LeCluyse ...

co-author countries: United States of America 🇺🇸

Contributors: D. Rotroff*, A. Beam, D. Dix*, A. Farmer, K. Freeman, K. Houck*, R. Judson*, E. Lecluyse ...

MeSH headings : Adult; Animals; Cell Shape / drug effects; Cells, Cultured; Cholesterol / biosynthesis; Environmental Pollutants / chemistry; Environmental Pollutants / metabolism; Environmental Pollutants / toxicity; Gene Expression Regulation / drug effects; Hepatocytes / cytology; Hepatocytes / drug effects; Hepatocytes / enzymology; Hepatocytes / metabolism; Humans; Male; Middle Aged; Models, Biological; Rats; Signal Transduction / drug effects; Xenobiotics / chemistry; Xenobiotics / metabolism; Xenobiotics / toxicity
Source: ORCID
Added: May 14, 2019

2010 journal article

Research needs for community-based risk assessment: findings from a multi-disciplinary workshop

J Expos Sci Environ Epidemiol, 20(2), 186–195.

By: Y. Sanchez*, K. Deener*, E. Hubal*, C. Knowlton*, D. Reif* & D. Segal*

co-author countries: United States of America 🇺🇸

Contributors: Y. Sanchez*, K. Deener*, E. Hubal*, C. Knowlton*, D. Reif* & D. Segal*

author keywords: population-based studies; epidemiology; exposure modeling; analytical methods; empirical/statistical modeling; PBPK modeling
MeSH headings : Humans; Needs Assessment; Research; Risk Assessment; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2010 journal article

Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening.

Toxicological Sciences, 117(2), 348–358.

By: D. Rotroff*, B. Wetmore*, D. Dix*, S. Ferguson, H. Clewell*, K. Houck*, E. Lecluyse, M. Andersen* ...

co-author countries: United States of America 🇺🇸

Contributors: D. Rotroff*, B. Wetmore*, D. Dix*, S. Ferguson, H. Clewell*, K. Houck*, E. LeCluyse, M. Andersen* ...

author keywords: reverse dosimetry; human exposure; ToxCast; high-throughput screening
MeSH headings : Cells, Cultured; Dose-Response Relationship, Drug; Female; Gas Chromatography-Mass Spectrometry; Hepatocytes / drug effects; Hepatocytes / metabolism; High-Throughput Screening Assays / methods; Humans; Male; Metabolic Clearance Rate; Protein Binding / drug effects; Risk Assessment; Toxicity Tests; Xenobiotics / classification; Xenobiotics / metabolism; Xenobiotics / toxicity
Source: ORCID
Added: May 14, 2019

2010 journal article

Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program.

Chemical Research in Toxicology, 23(3), 578–590.

By: M. Martin*, D. Dix*, R. Judson*, R. Kavlock*, D. Reif*, A. Richard*, D. Rotroff*, S. Romanov* ...

co-author countries: United States of America 🇺🇸

Contributors: M. Martin*, D. Dix*, R. Judson*, R. Kavlock*, D. Reif*, A. Richard*, D. Rotroff*, S. Romanov* ...

MeSH headings : Animals; Biosensing Techniques / economics; Biosensing Techniques / instrumentation; Biosensing Techniques / methods; Environmental Pollutants / adverse effects; Hep G2 Cells; Rabbits; Rats; Receptors, Cytoplasmic and Nuclear / genetics; Response Elements / drug effects; Transcription Factors / genetics; Transcription, Genetic / drug effects
Source: ORCID
Added: May 14, 2019

2010 journal article

Endocrine Profiling and Prioritization of Environmental Chemicals Using ToxCast Data

Environ Health Perspect, 118(12), 1714–1720.

By: D. Reif*, M. Martin*, S. Tan*, K. Houck*, R. Judson*, A. Richard*, T. Knudsen*, D. Dix*, R. Kavlock*

co-author countries: United States of America 🇺🇸

Contributors: D. Reif*, M. Martin*, S. Tan*, K. Houck*, R. Judson*, A. Richard*, T. Knudsen*, D. Dix*, R. Kavlock*

author keywords: androgen; chemical prioritization; data integration; endocrine disruption; estrogen; screening; ToxCast; toxicity profile; ToxPi
MeSH headings : Decision Support Techniques; Endocrine Disruptors / classification; Endocrine Disruptors / toxicity; Endocrine System / drug effects; Environmental Pollutants / classification; Environmental Pollutants / toxicity; Signal Transduction / drug effects; Toxicity Tests / methods
Source: ORCID
Added: May 14, 2019

2010 journal article

Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity.

Environmental Science and Technology, 44(15), 5979–5985.

By: R. Judson*, M. Martin*, D. Reif*, K. Houck*, T. Knudsen*, D. Rotroff*, M. Xia*, S. Sakamuru* ...

co-author countries: United States of America 🇺🇸

Contributors: R. Judson*, M. Martin*, D. Reif*, K. Houck*, T. Knudsen*, D. Rotroff*, M. Xia*, S. Sakamuru* ...

MeSH headings : Chemical Hazard Release; Endocrine Disruptors / analysis; Environmental Restoration and Remediation; Lipids / toxicity; Receptors, Estrogen / metabolism; Surface-Active Agents / toxicity; Water Pollutants, Chemical / toxicity
Source: ORCID
Added: May 14, 2019

2010 review

Auriculotherapy for Pain Management: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

[Review of ]. JOURNAL OF ALTERNATIVE AND COMPLEMENTARY MEDICINE, 16(10), 1097–1108.

By: G. Asher*, D. Jonas*, R. Coeytaux*, A. Reilly*, Y. Loh*, A. Motsinger-Reif n, S. Winham n

co-author countries: United States of America 🇺🇸
MeSH headings : Acupuncture, Ear; Analgesia; Humans; Pain Management; Pain Measurement; Perioperative Period; Randomized Controlled Trials as Topic
Source: Web Of Science
Added: August 6, 2018

2010 review

Unifying Themes in Microbial Associations with Animal and Plant Hosts Described Using the Gene Ontology

[Review of ]. MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS, 74(4), 479–503.

By: T. Torto-Alalibo*, C. Collmer*, M. Gwinn-Giglio*, M. Lindeberg*, S. Meng n, M. Chibucos*, T. Tseng*, J. Lomax* ...

co-author countries: United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸

Contributors: T. Torto-Alalibo*, C. Collmer*, M. Gwinn-Giglio*, M. Lindeberg*, S. Meng n, M. Chibucos*, T. Tseng*, J. Lomax* ...

MeSH headings : Animals; Bacteria / genetics; Bacteria / metabolism; Bacterial Physiological Phenomena; Cell Adhesion; Computational Biology / methods; Fungi / genetics; Fungi / metabolism; Fungi / physiology; Host-Pathogen Interactions / genetics; Host-Pathogen Interactions / immunology; Plants / immunology; Plants / microbiology; Protein Transport; Symbiosis / genetics; Symbiosis / immunology; Virulence Factors
Sources: Web Of Science, ORCID
Added: August 6, 2018

2010 journal article

Global generic richness and distribution: new maps of the world of ants with examples of their use in the context of Asia

Asian Myrmecology, 3, 21–28.

Source: NC State University Libraries
Added: August 6, 2018

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