Works Published in 2015

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Displaying works 1 - 20 of 53 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2015 journal article

Comprehensive characterization of the Published Kinase Inhibitor Set

Nature Biotechnology, 34(1), 95–103.

By: J. Elkins*, V. Fedele*, M. Szklarz*, K. Abdul Azeez*, E. Salah*, J. Mikolajczyk*, S. Romanov*, N. Sepetov* ...

co-author countries: Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 United States of America 🇺🇸
MeSH headings : Glycosylation; Phosphotransferases / antagonists & inhibitors; Protein Kinase Inhibitors / pharmacology
Source: Crossref
Added: January 21, 2021

2015 journal article

Synchronized age-related gene expression changes across multiple tissues in human and the link to complex diseases

Scientific Reports, 5(1), 15145.

By: J. Yang, T. Huang, F. Petralia, Q. Long, B. Zhang, C. Argmann, Y. Zhao, C. Mobbs ...

MeSH headings : Adult; Aged; Aging / genetics; Animals; Cluster Analysis; Computational Biology / methods; Female; Gene Expression; Gene Expression Profiling; Gene Expression Regulation; Genetic Association Studies; Humans; Male; Mice; Middle Aged; Molecular Sequence Annotation; Mutation; Organ Specificity / genetics; Young Adult
Source: Crossref
Added: January 4, 2021

2015 journal article

Erratum: Gene expression in major depressive disorder

Molecular Psychiatry, 21(3), 444–444.

By: R. Jansen, B. Penninx*, V. Madar, K. Xia, Y. Milaneschi*, J. Hottenga, A. Hammerschlag*, A. Beekman ...

co-author countries: Netherlands 🇳🇱
Source: Crossref
Added: August 28, 2020

2015 journal article

Gene expression in major depressive disorder

Molecular Psychiatry, 21(3), 339–347.

By: R. Jansen*, B. Penninx*, V. Madar*, K. Xia*, Y. Milaneschi*, J. Hottenga*, A. Hammerschlag*, A. Beekman* ...

co-author countries: Netherlands 🇳🇱 United States of America 🇺🇸
MeSH headings : Adult; Anxiety Disorders / genetics; Cross-Sectional Studies; Depressive Disorder, Major / diagnosis; Depressive Disorder, Major / genetics; Female; Gene Expression / genetics; Gene Expression Regulation / genetics; Genetic Predisposition to Disease / genetics; Genome-Wide Association Study; Humans; Interleukin-6 / genetics; Interleukin-6 / metabolism; Killer Cells, Natural / metabolism; Longitudinal Studies; Male; Middle Aged; Polymorphism, Single Nucleotide / genetics; Signal Transduction / genetics
Source: Crossref
Added: August 28, 2020

2015 journal article

Predicting chemically-induced skin reactions. Part I: QSAR models of skin sensitization and their application to identify potentially hazardous compounds

Toxicology and Applied Pharmacology, 284(2), 262–272.

co-author countries: Brazil 🇧🇷 Ukraine 🇺🇦 United States of America 🇺🇸
author keywords: Skin sensitization; QSAR; Virtual screening; Skin toxicants
MeSH headings : Databases, Factual; Dermatitis, Allergic Contact / etiology; Dermatitis, Allergic Contact / immunology; Hazardous Substances / poisoning; Humans; Models, Chemical; Models, Immunological; Quantitative Structure-Activity Relationship; Skin / drug effects; Skin / immunology; Software
Source: Crossref
Added: February 24, 2020

2015 journal article

Materials Cartography: Representing and Mining Materials Space Using Structural and Electronic Fingerprints

Chemistry of Materials, 27(3), 735–743.

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2015 journal article

Predicting chemically-induced skin reactions. Part II: QSAR models of skin permeability and the relationships between skin permeability and skin sensitization

Toxicology and Applied Pharmacology, 284(2), 273–280.

co-author countries: Brazil 🇧🇷 Ukraine 🇺🇦 United States of America 🇺🇸
author keywords: Skin sensitization; Skin permeability; QSAR; Virtual screening; Skin toxicants
MeSH headings : Computer Simulation; Databases, Factual; Dermatitis, Allergic Contact / etiology; Dermatitis, Allergic Contact / immunology; Dermatitis, Allergic Contact / metabolism; Hazardous Substances / poisoning; Humans; Models, Theoretical; Permeability; Quantitative Structure-Activity Relationship; Skin / drug effects; Skin / immunology; Skin / metabolism; Skin Absorption / physiology; Software
Source: Crossref
Added: February 24, 2020

2015 journal article

Drug Side Effect Profiles as Molecular Descriptors for Predictive Modeling of Target Bioactivity

Molecular Informatics, 34(2-3), 160–170.

co-author countries: United States of America 🇺🇸
author keywords: Side effects; Machine learning; QSAR; Drug repurposing
MeSH headings : Animals; Data Mining / methods; Dopamine Antagonists / adverse effects; Humans; MEDLINE; Models, Biological; Serotonin Antagonists / adverse effects
Source: Crossref
Added: February 24, 2020

2015 journal article

Genome-wide association meta-analysis identifies five modifier loci of lung disease severity in cystic fibrosis

Nature Communications, 6(1).

By: H. Corvol*, S. Blackman*, P. Boëlle*, P. Gallins*, R. Pace*, J. Stonebraker*, F. Accurso*, A. Clement* ...

co-author countries: Canada 🇨🇦 France 🇫🇷 United States of America 🇺🇸
MeSH headings : Adolescent; Adult; Amino Acid Transport Systems; Amino Acid Transport Systems, Neutral / genetics; Child; Cystic Fibrosis / genetics; Cystic Fibrosis / metabolism; Cystic Fibrosis / pathology; Female; Genome-Wide Association Study; Humans; Lung / metabolism; Lung / pathology; Male; Middle Aged; Mucin-4 / genetics; Mucins / genetics; Severity of Illness Index; Transcription Factors / genetics; Young Adult
Source: Crossref
Added: February 24, 2020

2015 journal article

Prediction of human population responses to toxic compounds by a collaborative competition

Nature Biotechnology, 33(9), 933–940.

By: F. Eduati, L. Mangravite, T. Wang, H. Tang, J. Bare, R. Huang, T. Norman, M. Kellen ...

co-author countries: Spain 🇪🇸
MeSH headings : Computer Simulation; Dose-Response Relationship, Drug; Genetic Predisposition to Disease / genetics; Genetics, Population; Hazardous Substances / toxicity; High-Throughput Screening Assays / methods; Humans; Incidence; Lymphocytes / cytology; Lymphocytes / drug effects; Lymphocytes / physiology; Models, Genetic; Risk Assessment / methods; Toxicity Tests / methods
Source: Crossref
Added: February 24, 2020

2015 journal article

Erratum: Prediction of human population responses to toxic compounds by a collaborative competition

Nature Biotechnology, 33(10), 1109–1109.

By: F. Eduati, L. Mangravite, T. Wang*, H. Tang, J. Bare, R. Huang, T. Norman, M. Kellen ...

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2015 journal article

Identification of Novel Gene Targets and Putative Regulators of Arsenic-Associated DNA Methylation in Human Urothelial Cells and Bladder Cancer

Chemical Research in Toxicology, 28(6), 1144–1155.

By: J. Rager*, S. Tilley*, S. Tulenko*, L. Smeester*, P. Ray*, A. Yosim*, J. Currier*, M. Ishida* ...

co-author countries: Mexico 🇲🇽 United States of America 🇺🇸
MeSH headings : Adult; Aged; Arsenic / metabolism; Arsenic / toxicity; Cell Transformation, Neoplastic / chemically induced; DNA Methylation / drug effects; DNA Methylation / genetics; Female; Humans; Middle Aged; Urinary Bladder Neoplasms / chemically induced; Urinary Bladder Neoplasms / genetics; Urinary Bladder Neoplasms / pathology; Urothelium / cytology; Urothelium / drug effects; Young Adult
Source: Crossref
Added: February 24, 2020

2015 journal article

Pharmacometabolomic Assessments of Atenolol and Hydrochlorothiazide Treatment Reveal Novel Drug Response Phenotypes

CPT: Pharmacometrics & Systems Pharmacology, 4(11), 669–679.

By: D. Rotroff n, M. Shahin*, S. Gurley*, H. Zhu*, A. Motsinger-Reif n, M. Meisner n, A. Beitelshees*, O. Fiehn* ...

co-author countries: Saudi Arabia 🇸🇦 United States of America 🇺🇸
Source: Crossref
Added: February 24, 2020

2015 journal article

Erratum: Corrigendum: Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance

Nature Genetics, 47(6), 690–690.

By: J. Crowley, V. Zhabotynsky, W. Sun, S. Huang, I. Pakatci, Y. Kim, J. Wang, A. Morgan ...

Source: Crossref
Added: February 24, 2020

2015 journal article

Analyses of allele-specific gene expression in highly divergent mouse crosses identifies pervasive allelic imbalance

Nature Genetics, 47(4), 353–360.

By: J. Crowley*, V. Zhabotynsky*, W. Sun*, S. Huang*, I. Pakatci*, Y. Kim*, J. Wang*, A. Morgan* ...

co-author countries: Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Alleles; Allelic Imbalance / genetics; Animals; Crosses, Genetic; Dosage Compensation, Genetic; Female; Gene Expression; Genetic Speciation; Humans; Male; Mice / genetics; Mice, Knockout; Phylogeny; Polymorphism, Single Nucleotide
Source: Crossref
Added: February 24, 2020

2015 book

Exploiting solved genomes of plant-parasitic nematodes to understand parasitism

In Advances in Botanical Research (Vol. 73, pp. 241–258).

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: January 30, 2020

2015 journal article

Molecular cloning, functional characterization, and evolutionary analysis of vitamin D receptors isolated from basal vertebrates

PLoS ONE, 10(4).

By: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, D. Reif n & S. Kullman n

co-author countries: United States of America 🇺🇸

Contributors: E. Kollitz n, G. Zhang n, M. Hawkins n, G. Whitfield*, D. Reif n & S. Kullman n

MeSH headings : Animals; Base Sequence; Cloning, Molecular; Computational Biology; Electrophoretic Mobility Shift Assay; Evolution, Molecular; Fishes / genetics; Likelihood Functions; Models, Genetic; Molecular Sequence Data; Petromyzon / genetics; Phylogeny; Protein Binding; Protein Interaction Mapping; Receptors, Calcitriol / genetics; Sequence Analysis, DNA; Skates, Fish / genetics; Species Specificity; Two-Hybrid System Techniques
Source: ORCID
Added: May 14, 2019

2015 journal article

Food for Thought...: Toxicity testing in the 21st century beyond environmental chemicals

Altex, 32(3), 171–181.

By: C. Rovida*, S. Asakura*, M. Daneshian*, H. Hofman-Huether*, M. Leist*, L. Meunier*, D. Reif n, A. Rossi* ...

co-author countries: Belgium 🇧🇪 Germany 🇩🇪 Italy 🇮🇹 Japan 🇯🇵 Netherlands 🇳🇱 United States of America 🇺🇸

Contributors: C. Rovida*, S. Asakura*, M. Daneshian*, H. Hofman-Huether*, M. Leist*, L. Meunier*, D. Reif n, A. Rossi* ...

author keywords: food ingredients; drugs; Tox21c; safety assessment
MeSH headings : Animal Testing Alternatives / methods; Animals; Drug Approval; Drug Evaluation / methods; Drug Industry; Humans; In Vitro Techniques; Risk Assessment; Safety / standards; Toxicity Tests / methods; United States; United States Environmental Protection Agency
Source: ORCID
Added: May 14, 2019

2015 book

Embracing complexity: Searching for gene-gene and gene environment interactions in genetic epidemiology

In Genomics and Proteomics: Principles, Technologies, and Applications (pp. 19–58).

By: A. Motsinger & D. Reif

Contributors: A. Motsinger & D. Reif

Source: ORCID
Added: May 14, 2019

2015 journal article

Data-driven asthma endotypes defined from blood biomarker and gene expression data

PLoS ONE, 10(2).

By: B. George*, D. Reif*, J. Gallagher*, C. Williams-DeVane*, B. Heidenfelder*, E. Hudgens*, W. Jones*, L. Neas*, E. Cohen Hubal*, S. Edwards*

co-author countries: United States of America 🇺🇸

Contributors: B. George*, D. Reif*, J. Gallagher*, C. Williams-DeVane*, B. Heidenfelder*, E. Hudgens*, W. Jones*, L. Neas*, E. Cohen Hubal*, S. Edwards*

MeSH headings : Adaptive Immunity; Anti-Asthmatic Agents / therapeutic use; Asthma / blood; Asthma / classification; Asthma / genetics; Asthma / immunology; Biomarkers / blood; Decision Trees; Eosinophilia / complications; Humans; Immunity, Innate; Medical Informatics / methods; Metabolic Syndrome / complications; Transcriptome
Source: ORCID
Added: May 14, 2019

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