Works Published in 2017

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Displaying works 1 - 20 of 50 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2017 journal article

Genome-wide common and rare variant analysis provides novel insights into clozapine-associated neutropenia

Molecular Psychiatry, 22(10), 1502–1508.

By: S. Legge*, M. Hamshere*, S. Ripke*, A. Pardinas*, J. Goldstein*, E. Rees*, A. Richards*, G. Leonenko* ...

co-author countries: Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Iceland 🇮🇸 Sweden 🇸🇪 United States of America 🇺🇸
MeSH headings : Carrier Proteins / genetics; Case-Control Studies; Clozapine / adverse effects; Clozapine / therapeutic use; Exome; Female; Genome-Wide Association Study; HLA-DQ beta-Chains / genetics; Humans; Male; Neutropenia / chemically induced; Neutropenia / genetics; Neutropenia / metabolism; Odds Ratio; Schizophrenia / drug therapy; Schizophrenia / genetics; Solute Carrier Organic Anion Transporter Family Member 1B3 / genetics
Source: Crossref
Added: January 28, 2021

2017 journal article

Reaction: Molecular Modeling for Novel Antibacterials

Chem, 3(1), 13–14.

By: D. Fourches n

co-author countries: United States of America 🇺🇸
Source: Crossref
Added: December 21, 2020

2017 journal article

Cheminformatics Modeling of Amine Solutions for Assessing their CO2Absorption Properties

Molecular Informatics, 36(7), 1600143.

By: M. Kuenemann n & D. Fourches n

co-author countries: United States of America 🇺🇸
author keywords: amine scrubbing; molecular modeling; QSPR; CO2 recycling
MeSH headings : Algorithms; Amines / chemistry; Carbon Dioxide / analysis; Carbon Dioxide / chemistry; Cluster Analysis; Databases, Factual; Machine Learning; Models, Chemical; Models, Molecular; Quantitative Structure-Activity Relationship; Reproducibility of Results; Solutions
Source: Crossref
Added: December 21, 2020

2017 journal article

Genetic effects on gene expression across human tissues

Nature, 550(7675), 204–213.

Fred Wright

MeSH headings : Alleles; Chromosomes, Human / genetics; Disease / genetics; Female; Gene Expression Profiling; Gene Expression Regulation / genetics; Genetic Variation; Genome, Human / genetics; Genotype; Humans; Male; Organ Specificity / genetics; Quantitative Trait Loci / genetics
Source: Crossref
Added: December 19, 2020

2017 journal article

The impact of rare variation on gene expression across tissues

Nature, 550(7675), 239–243.

By: X. Li*, Y. Kim*, E. Tsang*, J. Davis*, F. Damani*, C. Chiang*, G. Hess*, Z. Zappala* ...

co-author countries: United States of America 🇺🇸
MeSH headings : Bayes Theorem; Female; Gene Expression Profiling; Genetic Variation / genetics; Genome, Human / genetics; Genomics; Genotype; Humans; Male; Models, Genetic; Organ Specificity / genetics; Sequence Analysis, RNA
Source: Crossref
Added: December 19, 2020

2017 journal article

Landscape of X chromosome inactivation across human tissues

Nature, 550(7675), 244–248.

co-author countries: United States of America 🇺🇸
MeSH headings : Chromosomes, Human, X / genetics; Female; Genes, X-Linked / genetics; Genome, Human / genetics; Genomics; Humans; Male; Organ Specificity / genetics; Phenotype; Sequence Analysis, RNA; Single-Cell Analysis; Transcriptome / genetics; X Chromosome Inactivation / genetics
Source: Crossref
Added: December 19, 2020

2017 journal article

Dynamic landscape and regulation of RNA editing in mammals

Nature, 550(7675), 249–254.

By: M. Tan*, Q. Li*, R. Shanmugam*, R. Piskol*, J. Kohler*, A. Young*, K. Liu*, R. Zhang* ...

co-author countries: Australia 🇦🇺 Czechia 🇨🇿 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Italy 🇮🇹 Singapore 🇸🇬 United States of America 🇺🇸
MeSH headings : Adenosine Deaminase / genetics; Adenosine Deaminase / metabolism; Animals; Female; Genotype; HEK293 Cells; Humans; Male; Mice; Muscles / metabolism; Nuclear Proteins / metabolism; Organ Specificity / genetics; Primates / genetics; Proteolysis; RNA Editing / genetics; RNA-Binding Proteins / genetics; RNA-Binding Proteins / metabolism; Spatio-Temporal Analysis; Species Specificity; Transcriptome / genetics
Source: Crossref
Added: December 19, 2020

2017 journal article

Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

Scientific Data, 4(1).

By: L. St John-Williams*, C. Blach*, J. Toledo*, D. Rotroff n, S. Kim*, K. Klavins*, R. Baillie*, X. Han* ...

co-author countries: Austria 🇦🇹 Germany 🇩🇪 United States of America 🇺🇸
MeSH headings : Alzheimer Disease / drug therapy; Alzheimer Disease / genetics; Alzheimer Disease / metabolism; Cognitive Dysfunction; Cohort Studies; Humans; Metabolomics; Neuroimaging
Source: Crossref
Added: February 21, 2020

2017 journal article

GUT DERIVED BILE ACID METABOLITES CORRELATE WITH STRUCTURAL AND FUNCTIONAL NEUROIMAGING MEASURES IN ALZHEIMER’S DISEASE

Alzheimer's & Dementia, 13(7), P543–P544.

By: K. Nho n, S. Dehkordi, A. Motsinger-Reif*, R. Baillie, S. Bhattacharyya, J. Tenenbaum, J. Thompson, L. St. John Williams ...

co-author countries: Austria 🇦🇹 United States of America 🇺🇸
Source: Crossref
Added: February 21, 2020

2017 journal article

Metabolic network failures in Alzheimer's disease: A biochemical road map

Alzheimer's & Dementia, 13(9), 965–984.

By: J. Toledo*, M. Arnold*, G. Kastenmüller*, R. Chang*, R. Baillie*, X. Han*, M. Thambisetty*, J. Tenenbaum* ...

co-author countries: Austria 🇦🇹 Germany 🇩🇪 United Kingdom of Great Britain and Northern Ireland 🇬🇧 Netherlands 🇳🇱 Qatar 🇶🇦 United States of America 🇺🇸
author keywords: Metabolomics; Metabonomics; Pharmacometabolomics; Pharmacometabonomics; Biomarkers; Serum; Metabolism; Systems biology; Biochemical networks; Precision medicine; Alzheimer's disease; Dementia; Branched-chain amino acids; Sphingomyelins; Phospholipids; Acylcarnitines
MeSH headings : Aged; Aged, 80 and over; Aging / blood; Alzheimer Disease / blood; Alzheimer Disease / cerebrospinal fluid; Alzheimer Disease / complications; Alzheimer Disease / diagnostic imaging; Amino Acids / blood; Amyloid beta-Peptides / metabolism; Aniline Compounds / metabolism; Cognitive Dysfunction / blood; Cognitive Dysfunction / diagnostic imaging; Cognitive Dysfunction / etiology; Cohort Studies; Cross-Sectional Studies; Fasting; Female; Humans; Male; Metabolic Diseases / blood; Metabolic Diseases / cerebrospinal fluid; Metabolic Diseases / diagnostic imaging; Metabolic Diseases / etiology; Metabolic Networks and Pathways / physiology; Metabolomics / methods; Peptide Fragments / metabolism; Phosphatidylcholines / blood; Phosphatidylcholines / metabolism; Sphingomyelins / blood; Thiazoles / metabolism; tau Proteins / cerebrospinal fluid
Source: Crossref
Added: February 21, 2020

2017 journal article

Genetic Variants in HSD17B3 , SMAD3 , and IPO11 Impact Circulating Lipids in Response to Fenofibrate in Individuals With Type 2 Diabetes

Clinical Pharmacology & Therapeutics, 103(4), 712–721.

co-author countries: Spain 🇪🇸 United States of America 🇺🇸
MeSH headings : Aldehyde Reductase / genetics; Animals; Diabetes Mellitus, Type 2 / complications; Diabetes Mellitus, Type 2 / genetics; Diabetes Mellitus, Type 2 / metabolism; Dyslipidemias / blood; Dyslipidemias / complications; Dyslipidemias / drug therapy; Dyslipidemias / genetics; Female; Fenofibrate / administration & dosage; Fenofibrate / pharmacokinetics; Gene Expression Profiling / methods; Genome-Wide Association Study; Humans; Hypolipidemic Agents / administration & dosage; Hypolipidemic Agents / pharmacokinetics; Lipid Metabolism / drug effects; Lipid Metabolism / genetics; Male; Mice; Middle Aged; Pharmacogenomic Testing / methods; Signal Transduction / drug effects; Smad3 Protein / genetics; beta Karyopherins / genetics
Source: Crossref
Added: February 21, 2020

2017 journal article

Genetics of Hereditary Ataxia in Scottish Terriers

Journal of Veterinary Internal Medicine, 31(4), 1132–1139.

By: G. Urkasemsin n, D. Nielsen n, A. Singleton*, S. Arepalli*, D. Hernandez*, C. Agler n, N. Olby n

co-author countries: United States of America 🇺🇸
author keywords: Canine; Cerebellar abiotrophy; Cerebellar ataxia; Neurodegeneration
MeSH headings : Animals; Brain / diagnostic imaging; Dog Diseases / diagnostic imaging; Dog Diseases / genetics; Dogs; Female; Genetic Linkage / genetics; Genome-Wide Association Study / veterinary; Homozygote; Magnetic Resonance Imaging / veterinary; Male; Neuroimaging / veterinary; Pedigree; Spinocerebellar Degenerations / diagnostic imaging; Spinocerebellar Degenerations / genetics; Spinocerebellar Degenerations / veterinary
Sources: Crossref, ORCID
Added: January 7, 2020

2017 article

Integrating Morphological and Behavioral Phenotypes in Developing Zebrafish

The Rights and Wrongs of Zebrafish: Behavioral Phenotyping of Zebrafish, pp. 259–272.

co-author countries: United States of America 🇺🇸
Source: ORCID
Added: May 14, 2019

2017 journal article

Embryonic exposure to TCDD impacts osteogenesis of the axial skeleton in Japanese medaka, Oryzias latipes

Toxicological Sciences, 155(2), 485–496.

By: A. Watson, A. Planchart n, C. Mattingly n, C. Winkler*, D. Reif n & S. Kullman n

co-author countries: Singapore 🇸🇬 United States of America 🇺🇸

Contributors: A. Watson, A. Planchart n, C. Mattingly n, C. Winkler*, D. Reif n & S. Kullman n

author keywords: receptor, aryl hydrocarbon; gene expression/regulation, bone; transgenic models; methods, developmental/teratology; reproductive and developmental toxicology
MeSH headings : Animals; Calcification, Physiologic / drug effects; Down-Regulation / drug effects; Microscopy, Confocal; Musculoskeletal Diseases / metabolism; Oryzias / embryology; Osteogenesis / drug effects; Polychlorinated Dibenzodioxins / toxicity; Real-Time Polymerase Chain Reaction; Skeleton / drug effects; Skeleton / metabolism; Trans-Activators / drug effects
Source: ORCID
Added: May 14, 2019

2017 journal article

An introduction to terminology and methodology of chemical synergy-perspectives from across disciplines

Frontiers in Pharmacology, 8(APR).

co-author countries: United States of America 🇺🇸
author keywords: synergy; mixtures; non-additive; interactions; drug combinations
Source: ORCID
Added: May 14, 2019

2017 journal article

A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades

Toxicology and Applied Pharmacology, 314, 109–117.

co-author countries: United States of America 🇺🇸
author keywords: Zebrafish; High-dimensional; Bayesian; Developmental cascade; ToxRefDB; Risk assessment; Multiple endpoints; Multivariate; Scoring
MeSH headings : Animals; Models, Theoretical; Multivariate Analysis; Phenotype; Zebrafish / embryology
Source: ORCID
Added: May 14, 2019

2017 journal article

A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish

PLOS ONE, 12(1).

co-author countries: United States of America 🇺🇸

Ed(s): S. Neuhauss

MeSH headings : Animals; Biometry / methods; High-Throughput Screening Assays / methods; Models, Statistical; Zebrafish
Source: ORCID
Added: May 14, 2019

2017 journal article

RealityConvert: a tool for preparing 3D models of biochemical structures for augmented and virtual reality

BIOINFORMATICS, 33(23), 3816–3818.

co-author countries: United States of America 🇺🇸
MeSH headings : Computational Biology / methods; Models, Molecular; Molecular Conformation; Software; Virtual Reality
Source: Web Of Science
Added: August 6, 2018

2017 journal article

The Effect of Heart Disease on Anesthetic Complications During Routine Dental Procedures in Dogs

JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION, 53(4), 206–213.

By: J. Carter n, A. Motsinger-Reif n, W. Krug n & B. Keene n

co-author countries: Australia 🇦🇺 United States of America 🇺🇸
MeSH headings : Anesthesia / adverse effects; Anesthesia / veterinary; Animals; Case-Control Studies; Dental Prophylaxis / veterinary; Dog Diseases / etiology; Dogs; Heart Diseases / complications; Heart Diseases / veterinary; Intraoperative Complications / etiology; Intraoperative Complications / veterinary; Retrospective Studies; Risk Factors
Source: Web Of Science
Added: August 6, 2018

2017 journal article

Data descriptor: Targeted metabolomics and medication classification data from participants in the ADNI1 cohort

Scientific Data, 4.

By: L. St John-Williams, C. Blach, J. Toledo, D. Rotroff, S. Kim, K. Klavins, R. Baillie, X. Han ...

Source: NC State University Libraries
Added: August 6, 2018

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