Works Published in 2020

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Displaying works 1 - 20 of 41 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

INTEGRATIVE STATISTICAL METHODS FOR EXPOSURE MIXTURES AND HEALTH

ANNALS OF APPLIED STATISTICS, 14(4), 1945โ€“1963.

By: B. Reich*โ€‰, Y. Guan*, D. Fourches*, J. Warren, S. Sarnat & H. Chang

author keywords: Cheminformatics; collinearity; factor analysis; principal components; stochastic search; variable selection
Source: Web Of Science
Added: March 1, 2021

2020 journal article

Rapid Hazard Characterization of Environmental Chemicals Using a Compendium of Human Cell Lines from Different Organs

ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 37(4), 623โ€“638.

By: Z. Chenโ€‰*, Y. Liu, F. Wright, W. Chiu & I. Rusyn

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
Source: Web Of Science
Added: February 15, 2021

2020 journal article

Systematic Comparisons for Composition Profiles, Taxonomic Levels, and Machine Learning Methods for Microbiome-Based Disease Prediction

FRONTIERS IN MOLECULAR BIOSCIENCES, 7.

By: K. Song n, F. Wright n & Y. Zhou nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: phenotype prediction; machine learning method; k-mers; operational taxonomic unit (OTU); amplicon sequence variant (ASV); phylogenetic analysis
Source: Web Of Science
Added: January 19, 2021

2020 journal article

Unveiling molecular signatures of preeclampsia and gestational diabetes mellitus with multi-omics and innovative cheminformatics visualization tools

MOLECULAR OMICS, 16(6).

By: M. Odenkirk n, K. Strattonโ€‰*, M. Gritsenkoโ€‰*, L. Bramerโ€‰*, B. Webb-Robertson*, K. Bloodsworthโ€‰*, K. Weitzโ€‰*, A. Lipton* ...

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Case-Control Studies; Diabetes, Gestational / genetics; Female; Genomics; Humans; Lipidomics; Metabolic Networks and Pathways; Pre-Eclampsia / genetics; Pregnancy
Source: Web Of Science
Added: January 4, 2021

2020 personal communication

Questioning Existing Cancer Hazard Evaluation Standards in the Name of Statistics

Rusyn, I., Chiu, W. A., & Wright, F. A. (2020, October).

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Biological Assay; Glycine / analogs & derivatives; Humans; Neoplasms / epidemiology; Reference Standards
Source: Web Of Science
Added: December 14, 2020

2020 journal article

Leveraging the Comparative Toxicogenomics Database to Fill in Knowledge Gaps for Environmental Health: A Test Case for Air Pollution-induced Cardiovascular Disease

TOXICOLOGICAL SCIENCES, 177(2), 392โ€“404.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: environmental health; chemical-induced pathways; air pollution; cardiovascular disease; database
MeSH headings : Air Pollutants / toxicity; Air Pollution; Cardiovascular Diseases / chemically induced; Environmental Exposure; Environmental Health; Humans; Toxicogenetics
Source: Web Of Science
Added: December 14, 2020

2020 journal article

The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity

REPRODUCTIVE TOXICOLOGY, 96, 359โ€“369.

By: L. Truongโ€‰*, S. Marvel n, D. Reif nโ€‰, D. Thomas*, P. Pande*, S. Dasguptaโ€‰*, M. Simonich*, K. Watersโ€‰*, R. Tanguay*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Developmental toxicity; Flame retardants; Benchmark dose; Lowest effect concentration; Neurotoxicity; Classification model
MeSH headings : Animals; Embryo, Nonmammalian; Embryonic Development / drug effects; Flame Retardants / toxicity; Models, Animal; Neurotoxicity Syndromes; Risk Assessment; Structure-Activity Relationship; Teratogens / chemistry; Teratogens / toxicity; Zebrafish
Sources: Web Of Science, ORCID
Added: November 30, 2020

2020 journal article

Exploring the Limits of Combined Image/'omics Analysis for Non-cancer Histological Phenotypes

FRONTIERS IN GENETICS, 11.

By: P. Gallins n, E. Saghapour n & Y. Zhou nโ€‰

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: imaging; genomics; pathology; prediction; integration; histology; machine learning; embedding
Source: Web Of Science
Added: November 24, 2020

2020 journal article

Structural-based connectivity and omic phenotype evaluations (SCOPE): a cheminformatics toolbox for investigating lipidomic changes in complex systems

ANALYST, 145(22), 7197โ€“7209.

By: M. Odenkirk n, P. Zin nโ€‰, J. Ash n, D. Reif nโ€‰, D. Fourches n & E. Baker nโ€‰

co-author countries: Japan ๐Ÿ‡ฏ๐Ÿ‡ต United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Cheminformatics; Lipidomics; Lipids; Mass Spectrometry; Phenotype
Sources: Web Of Science, ORCID
Added: November 24, 2020

2020 journal article

The GTEx Consortium atlas of genetic regulatory effects across human tissues

SCIENCE, 369(6509), 1318โ€“1330.

By: F. Aguet, A. Barbeira, R. Bonazzola, A. Brown, S. Castel, B. Jo, S. Kasela, S. Kim-Hellmuth ...

MeSH headings : Datasets as Topic; Disease / genetics; Female; Gene Expression Regulation; Genome-Wide Association Study; Humans; Male; Organ Specificity; Quantitative Trait Loci; Sequence Analysis, RNA
Source: Web Of Science
Added: November 16, 2020

2020 journal article

Childrenโ€™s Environmental Health: A Systems Approach for Anticipating Impacts from Chemicals

International Journal of Environmental Research and Public Health, 17(22), 8337.

By: E. Hubalโ€‰*, D. Reif nโ€‰, R. Slover*, A. Mullikin* & J. Littleโ€‰*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: systems approach; children’ s environmental health
Source: ORCID
Added: November 13, 2020

2020 journal article

Structure-based virtual screening of perfluoroalkyl and polyfluoroalkyl substances (PFASs) as endocrine disruptors of androgen receptor activity using molecular docking and machine learning

ENVIRONMENTAL RESEARCH, 190.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Steroid hormones; Modeling; Tox21
MeSH headings : Endocrine Disruptors / analysis; Endocrine Disruptors / toxicity; Fluorocarbons / toxicity; Machine Learning; Mass Screening; Molecular Docking Simulation; Receptors, Androgen
Source: Web Of Science
Added: November 2, 2020

2020 journal article

Age and Genetic Background Modify Hybrid Male Sterility in House Mice

GENETICS, 216(2), 585โ€“597.

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: hybrid male sterility; aging; genetic background; spermatogenesis; mouse
MeSH headings : Aging / genetics; Aging / physiology; Animals; Female; Genetic Background; Genetic Loci; Hybridization, Genetic; Infertility, Male / genetics; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Multifactorial Inheritance
Source: Web Of Science
Added: November 2, 2020

2020 journal article

Classification of estrogenic compounds by coupling high content analysis and machine learning algorithms

PLOS COMPUTATIONAL BIOLOGY, 16(9).

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Algorithms; Cell Line; Estrogens / classification; Estrogens / metabolism; Humans; Machine Learning; Receptors, Estrogen / metabolism
Source: Web Of Science
Added: October 26, 2020

2020 journal article

Derivation of stable embryonic stem cell-like, but transcriptionally heterogenous, induced pluripotent stem cells from non-permissive mouse strains

MAMMALIAN GENOME, 31(9-12), 263โ€“286.

By: T. Garbutt n, K. Konganti*, T. Konneker n, A. Hillhouseโ€‰*, D. Phelps nโ€‰, A. Jones n, D. Aylor n, D. Threadgill*

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Animals; Biomarkers; Cell Differentiation; Cells, Cultured; Cellular Reprogramming / genetics; Embryonic Stem Cells / cytology; Embryonic Stem Cells / metabolism; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genetic Heterogeneity; Immunophenotyping; Induced Pluripotent Stem Cells / cytology; Induced Pluripotent Stem Cells / metabolism; Mice; Platelet Endothelial Cell Adhesion Molecule-1; Species Specificity; Transcriptome
Source: Web Of Science
Added: October 19, 2020

2020 journal article

Bacterial Community Structure Dynamics in Meloidogyne incognita-Infected Roots and Its Role in Worm-Microbiome Interactions

MSPHERE, 5(4).

By: T. Yergaliyevโ€‰*, R. Alexander-Shani*, H. Dimerets*, S. Pivonia*, D. Bird nโ€‰, S. Rachmilevitchโ€‰*, A. Szitenbergโ€‰*

co-author countries: Israel ๐Ÿ‡ฎ๐Ÿ‡ฑ United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Meloidogyne incognita; bacterial succession; microbiome; plant-microbe interactions; root knot nematode
MeSH headings : Animals; Bacteria / classification; Bacteria / metabolism; DNA Barcoding, Taxonomic; Genetic Variation; Host Microbial Interactions; Microbiota; Phylogeny; Plant Roots / microbiology; Plant Roots / parasitology; RNA, Ribosomal, 16S / genetics; Rhizosphere; Soil; Soil Microbiology; Tylenchoidea / microbiology; Tylenchoidea / physiology
Sources: Web Of Science, ORCID
Added: September 28, 2020

2020 article

Bayesian Matrix Completion for Hypothesis Testing

(2020, September 17).

David Reif

Source: ORCID
Added: September 24, 2020

2020 journal article

Photoinduced reconfiguration to control the protein-binding affinity of azobenzene-cyclized peptides

JOURNAL OF MATERIALS CHEMISTRY B, 8(33), 7413โ€“7427.

By: K. Day n, J. Schneible n, A. Young n, V. Pozdin*, G. Driesscheโ€‰ n, L. Gaffney n, R. Prodromou n, D. Freytes n ...

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Amino Acid Sequence; Azo Compounds / chemistry; Hydrogen-Ion Concentration; Isomerism; Osmolar Concentration; Peptides, Cyclic / chemistry; Photochemical Processes
Source: Web Of Science
Added: September 14, 2020

2020 journal article

In vitroandin vivoEvaluation ofin silicoPredicted Pneumococcal UDPG:PP Inhibitors

FRONTIERS IN MICROBIOLOGY, 11.

co-author countries: Belgium ๐Ÿ‡ง๐Ÿ‡ช United States of America ๐Ÿ‡บ๐Ÿ‡ธ
author keywords: Streptococcus pneumoniae; GalU; in silicomodeling; virulence; Galleria mellonella; novel drug target
Source: Web Of Science
Added: August 24, 2020

2020 journal article

Benchmarking 2D/3D/MD-QSAR Models for Imatinib Derivatives: How Far Can We Predict?

JOURNAL OF CHEMICAL INFORMATION AND MODELING, 60(7), 3342โ€“3360.

By: P. Zin nโ€‰, A. Borrel n & D. Fourches n

co-author countries: United States of America ๐Ÿ‡บ๐Ÿ‡ธ
MeSH headings : Benchmarking; Imatinib Mesylate / pharmacology; Molecular Docking Simulation; Quantitative Structure-Activity Relationship; Reproducibility of Results
Source: Web Of Science
Added: August 24, 2020

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