Center for Human Health and the Environment

Works Published in 2000

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Displaying works 1 - 20 of 47 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2000 journal article

Identification and Characterization of a cDNA Encoding Cytochrome P450 3A from the Fresh Water Teleost Medaka (Oryzias latipes)

Archives of Biochemistry and Biophysics, 380(1), 29–38.

By: S. Kullman*, J. Hamm* & D. Hinton*

author keywords: medaka; cytochrome P450; CYP3A; steroid metabolism
MeSH headings : Amino Acid Sequence; Animals; Aryl Hydrocarbon Hydroxylases; Base Sequence; Blotting, Northern; Blotting, Western; Cell Line; Cloning, Molecular; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System / biosynthesis; Cytochrome P-450 Enzyme System / genetics; DNA, Complementary / metabolism; Female; Fishes / genetics; Gene Library; Humans; Isoenzymes / biosynthesis; Isoenzymes / genetics; Liver / metabolism; Male; Microsomes, Liver / metabolism; Molecular Sequence Data; Oxidoreductases, N-Demethylating / biosynthesis; Oxidoreductases, N-Demethylating / genetics; RNA / metabolism; Recombinant Proteins / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Sex Factors; Testosterone / metabolism
TL;DR: Results suggests that O. latipes contains multiple forms of CYP3A, andComparisons of the deduced amino acid sequence to other known cytochrome P450 sequences indicate that this gene product is most similar to the CYP2A gene family. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: September 13, 2022

2000 conference paper

Complicated Urinary Tract Infections In 100 Dogs: A Retrospective Study

Seguin, A., Vaden, S., Levine, J., & Stone, E. (2000, May). Presented at the American College of Veterinary Internal Medicine, Seattle, Washington.

By: A. Seguin, S. Vaden, J. Levine & E. Stone

Event: American College of Veterinary Internal Medicine at Seattle, Washington

Source: NC State University Libraries
Added: October 16, 2021

2000 speech

Adult and Kitten Survival Time of Feral Cats in Managed Colonies in Randolph County

Nutter, F. B., Levine, J. F., & Stoskopf, M. K. (2000, June). Presented at the North Carolina Wildlife Disease Association.

By: F. Nutter, J. Levine & M. Stoskopf

Event: at North Carolina Wildlife Disease Association

Source: NC State University Libraries
Added: October 16, 2021

2000 conference paper

Prevalence of Bacterial Foodborne Pathogens in Shellfish

Tlamka, B., Pitts, T., Levine, J., French, J., Mare, C., & Joens, L. (2000, December). Presented at the Conference of Research Workers in Animal Diseases (CRWAD), Chicago, IL.

By: B. Tlamka, T. Pitts, J. Levine, J. French, C. Mare & L. Joens

Event: Conference of Research Workers in Animal Diseases (CRWAD) at Chicago, IL

Source: NC State University Libraries
Added: October 16, 2021

2000 journal article

Physical mapping of male fertility and meiotic drive quantitative trait loci in the mouse t complex using chromosome deficiencies

Genetics, 155(2), 803–812. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034084813&partnerID=MN8TOARS

By: A. Planchart, Y. You & J. Schimenti

Contributors: A. Planchart, Y. You & J. Schimenti

Source: ORCID
Added: March 16, 2021

2000 journal article

An experimental and theoretical study of the gas-phase decomposition of monoprotonated peptide nucleic acids

Journal of the American Society for Mass Spectrometry, 11(7), 615–625.

By: J. Flora*, D. Shillady* & D. Muddiman*

MeSH headings : Acetylation; Cyclotrons; Fourier Analysis; Gas Chromatography-Mass Spectrometry; Molecular Weight; Peptide Nucleic Acids / chemistry; Protons; Terminology as Topic
TL;DR: Electrospray ionization coupled with Fourier transform ion cyclotron resonance mass spectrometry shows great potential as a tool for the characterization and structural elucidation of these oligonucleotides. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 27, 2021

2000 journal article

A dual electrospray ionization source combined with hexapole accumulation to achieve high mass accuracy of biopolymers in Fourier transform ion cyclotron resonance mass spectrometry

Journal of the American Society for Mass Spectrometry, 11(10), 876–883.

By: J. Hannis* & D. Muddiman*

MeSH headings : Biopolymers / chemistry; Calibration; Cyclotrons; Fourier Analysis; Mass Spectrometry; Reverse Transcriptase Polymerase Chain Reaction; Spectrophotometry, Ultraviolet
TL;DR: An ESI source employed with hexapole accumulation and gated trapping provides a novel method of using an internal standard to achieve high mass accuracies in Fourier transform ion cyclotron resonance mass spectrometry, illustrating this method’s use for characterizing large biomolecules such as those encountered in genomics and proteomics related research. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021

2000 journal article

Preparation of single-stranded PCR products for electrospray ionization mass spectrometry using the DNA repair enzyme lambda exonuclease

The Analyst, 125(4), 619–626.

By: A. Null*, J. Hannis* & D. Muddiman*

MeSH headings : Base Sequence; DNA, Single-Stranded; Exodeoxyribonucleases; Mass Spectrometry; Molecular Sequence Data; Polymerase Chain Reaction / methods; Tyrosine 3-Monooxygenase / genetics; Viral Proteins
TL;DR: Lambda exonuclease clearly provides mass spectrometrists with a method to generate single-stranded PCR products and shows that one strand is preferentially adenylated over the other, which cannot be determined from the mass spectrum of the double-Stranded PCR product alone. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: February 12, 2021

2000 entry reference

Absolute Quantification of Proteins by Mass Spectrometry

TL;DR: All phases of the PC-IDMS workflow, from the SIL peptide production platforms to data analysis, are described and characterized in detail and an emphasis is placed on the practical quantitative aspects for each step of the workflow and their implication on quantitative accuracy. (via Semantic Scholar)
Sources: Crossref, ORCID
Added: January 18, 2021

2000 journal article

Measurement variability associated with KXRF bone lead measurement in young adults.

Environmental Health Perspectives, 108(3), 239–242.

By: J. Hoppin*, A. Aro*, H. Hu* & P. Ryan*

MeSH headings : Adolescent; Adult; Age Factors; Analysis of Variance; Bias; Body Burden; Bone Density; Boston; Cadaver; Environmental Exposure / analysis; Environmental Monitoring / methods; Female; Humans; Lead / analysis; Male; Radiography; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, X-Ray Emission / instrumentation; Spectrometry, X-Ray Emission / methods; Tibia / chemistry; Tibia / diagnostic imaging
TL;DR: The degree of variability that may be associated with bone lead measurements of young subjects with low bone lead concentrations using a standard spot-source KXRF instrument is described. (via Semantic Scholar)
Source: Crossref
Added: September 3, 2020

2000 journal article

Relationship between tissue-specific hydrocarbon profiles and lipid melting temperatures in the cockroach Blattella germanica

JOURNAL OF CHEMICAL ECOLOGY, 26(5), 1245–1263.

By: H. Young, J. Larabee, A. Gibbs & C. Schal

Contributors: H. Young, J. Larabee, A. Gibbs & C. Schal

Source: ORCID
Added: December 30, 2019

2000 journal article

Consentience on the necessity of Juvenile Hormone for vitellogenesis in the German cockroach - Reply

PHYSIOLOGICAL ENTOMOLOGY, 25(3), 208–210.

By: G. Holbrook, J. Bachmann & C. Schal

Contributors: G. Holbrook, J. Bachmann & C. Schal

Source: ORCID
Added: December 30, 2019

2000 journal article

Pancreatic cancer and serum organochlorine levels

Cancer Epidemiology Biomarkers and Prevention, 9(2), 199–205. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034003536&partnerID=MN8TOARS

By: J. Hoppin, P. Tolbert, E. Holly, J. Brock, S. Korrick, L. Altshul, R. Zhang, P. Bracci, V. Burse, L. Needham

Contributors: J. Hoppin, P. Tolbert, E. Holly, J. Brock, S. Korrick, L. Altshul, R. Zhang, P. Bracci, V. Burse, L. Needham

Source: ORCID
Added: September 13, 2019

2000 journal article

Occupational exposure to chlorophenol and the risk of nasal and nasopharyngeal cancers among U.S. Men aged 30 to 60

American Journal of Industrial Medicine, 37(5), 532–541.

By: M. Mirabelli*, J. Hoppin*, P. Tolbert*, R. Herrick, D. Gnepp* & E. Brann*

Contributors: M. Mirabelli*, J. Hoppin*, P. Tolbert*, R. Herrick, D. Gnepp* & E. Brann*

author keywords: occupational exposure; chlorophenols; nasal cancer; nasopharyngeal cancer
TL;DR: The hypothesis that occupational exposure to chlorophenol is a risk factor for nasal and nasopharyngeal cancer is supported, although the role of machining-related exposures warrants further assessment. (via Semantic Scholar)
Source: ORCID
Added: September 13, 2019

2000 journal article

Measurement variability associated with KXRF bone lead measurement in young adults

Environmental Health Perspectives, 108(3), 239–242. http://www.scopus.com/inward/record.url?eid=2-s2.0-0034128551&partnerID=MN8TOARS

By: J. Hoppin, A. Aro, H. Hu & P. Barry Ryan

Contributors: J. Hoppin, A. Aro, H. Hu & P. Barry Ryan

Source: ORCID
Added: September 13, 2019

2000 journal article

Letters to the Editor: The validity of self-reported prostrate cancer screening history

Preventive Medicine, 30(1), 78.

By: J. Hoppin*, E. Flagg*, J. Eley*, P. Tolbert*, T. Jordan & J. Price

Contributors: J. Hoppin*, E. Flagg*, J. Eley*, P. Tolbert*, T. Jordan & J. Price

MeSH headings : Adult; Aged; Aged, 80 and over; Focus Groups; Humans; Male; Mass Screening / methods; Middle Aged; Prostatic Neoplasms / diagnosis; Prostatic Neoplasms / prevention & control; Reproducibility of Results; Surveys and Questionnaires
UN Sustainable Development Goal Categories
4. Quality Education (OpenAlex)
Sources: ORCID, Crossref, NC State University Libraries
Added: September 13, 2019

2000 journal article

K-ras and p53 in pancreatic cancer: Association with medical history, histopathology, and environmental exposures in a population-based study

Cancer Epidemiology Biomarkers and Prevention, 9(11), 1223–1232. http://www.scopus.com/inward/record.url?eid=2-s2.0-0033729483&partnerID=MN8TOARS

By: R. Slebos, J. Hoppin, P. Tolbert, E. Holly, J. Brock, R. Zhang, P. Bracci, J. Foley ...

Contributors: R. Slebos, J. Hoppin, P. Tolbert, E. Holly, J. Brock, R. Zhang, P. Bracci, J. Foley ...

Source: ORCID
Added: September 13, 2019

2000 journal article

Evolutionary relationships between the amphibian, avian, and mammalian stomachs

Evolution and Development, 2(6), 348–359.

By: D. Smith*, R. Grasty*, N. Theodosiou*, C. Tabin* & N. Nascone-Yoder*

MeSH headings : Animals; Biological Evolution; Birds / anatomy & histology; Chick Embryo; Female; In Situ Hybridization; Mammals / anatomy & histology; Mice; Pregnancy; Stomach / anatomy & histology; Xenopus laevis / anatomy & histology
TL;DR: The global patterning of the gut is remarkably similar among the different vertebrate lineages, and the distinct compartments of gene expression that are found in the gut be necessary for the unique morphological specializations that distinguish the stomachs from terrestrial vertebrates. (via Semantic Scholar)
Source: Crossref
Added: July 20, 2019

2000 journal article

The zebrafish fth1, slc3a2, men1, pc, fgf3 and cycd1 genes define two regions of conserved synteny between linkage group 7 and human chromosome 11q13

GENE, 261(2), 235–242.

By: J. Yoder* & G. Litman*

author keywords: T51 radiation hybrid panel; LN54 radiation hybrid panel; hlx1; DBX; prkri; cd81
MeSH headings : Amino Acid Sequence; Animals; Antigens, CD / genetics; Carrier Proteins / genetics; Chromosome Mapping; Chromosomes, Human, Pair 11 / genetics; Conserved Sequence; Expressed Sequence Tags; Ferritins / genetics; Fusion Regulatory Protein-1; Genes / genetics; HSP40 Heat-Shock Proteins; Homeodomain Proteins / genetics; Humans; Membrane Proteins; Molecular Sequence Data; Protein Serine-Threonine Kinases / antagonists & inhibitors; Pyruvate Carboxylase / genetics; Radiation Hybrid Mapping; Repressor Proteins / genetics; Sequence Alignment; Sequence Homology, Amino Acid; Tetraspanin 28; Zebrafish / genetics
TL;DR: Six full-length zebrafish cDNAs, fth1, slc3a2, prkri, cd81, and pc, as well as one putative human gene, DBX were identified and their map positions ascertained, defining two regions of conserved synteny between linkage group 7 and 11q13. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2000 chapter

Immune-Type Diversity in the Absence of Somatic Rearrangement

In Current Topics in Microbiology and Immunology (Vol. 248, pp. 271–282).

By: J. Yoder* & G. Litman*

MeSH headings : Animals; Antibody Diversity; Biological Evolution; Fishes / genetics; Fishes / immunology; Gene Rearrangement; Genes, Immunoglobulin
TL;DR: The possibility that immune-type diversity is achieved in the absence of somatic rearrangement and that remnants of such systems could be operative in immune recognition in contemporary vertebrates is of extraordinary significance in terms of the authors' overall understanding of the relationships between adaptive and innate immune recognition. (via Semantic Scholar)
Sources: NC State University Libraries, ORCID
Added: August 6, 2018

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