Works Published in 2002
Displaying works 1 - 20 of 64 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2002 journal article
Toxicant induced differential gene expression and production of an aquatic gene array
The MDIBL Bulletin, 41, 58–61.
Source: NC State University Libraries
Added: September 16, 2022
2002 journal article
Molecular cloning of rainbow trout (Oncorhynchus mykiss) eggshell zona radiata protein complementary DNA: mRNA expression in 17β-estradiol- and nonylphenol-treated fish
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology, 132(2), 315–326.
author keywords: eggshell protein; cDNA cloning; liver; gene expression; xenoestrogen; biomarkers; environmental monitoring
MeSH headings : Amino Acid Sequence; Animals; Base Sequence; Cloning, Molecular; DNA Primers / genetics; DNA, Complementary / genetics; Egg Proteins / genetics; Egg Shell / chemistry; Estradiol / pharmacology; Gene Expression Profiling; Gene Expression Regulation / drug effects; Molecular Sequence Data; Oncorhynchus mykiss / genetics; Phenols / pharmacology; Phylogeny; Polymerase Chain Reaction; RNA, Messenger / genetics; RNA, Messenger / metabolism; Receptors, Estrogen / genetics; Vitellogenins / genetics
TL;DR:
The differential time-dependent transcriptional and translational expression and use of Zrp, ER and Vtg as sensitive biomarkers in environmental monitoring of endocrine disrupters in fish is discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: September 15, 2022
2002 conference paper
The Immunomodulatory Effects Of Triamcinolone On Peripheral Blood Phagocytosis And Tgf-b Mrna Expression In Hybrid Striped Bass
Johnson, A. K., Choi, K., Harms, C., Levine, J., & Law, M. (2002, April). Presented at the NCSU College of Veterinary Medicine Research Forum, Raleigh, North Carolina.
Event: NCSU College of Veterinary Medicine Research Forum at Raleigh, North Carolina
Source: NC State University Libraries
Added: October 16, 2021
2002 conference paper
Baseline Landcover Analysis To Evaluate Risk Of Mycobacterium Bovis Transmission In White-Tailed Deer And Cattle In Northeastern Michigan
Porter-Spalding, K. J., Kennedy-Stokopf, S., & Levine, J. (2002, April). Presented at the NCSU CVM Research Forum, Raleigh, North Carolina.
Event: NCSU CVM Research Forum at Raleigh, North Carolina
Source: NC State University Libraries
Added: October 16, 2021
2002 conference paper
Furosemide Continuous Rate Infusion in the Horse
Johansson, A. M., Gardner, S. Y., Levine, J. F., Papich, M. G., LaFevers, D. H., Goldman, R. B., … Atkins, C. E. (2002, April). Presented at the NCSU College of Veterinary Medicine Research Forum, Raleigh, North Carolina.
Event: NCSU College of Veterinary Medicine Research Forum at Raleigh, North Carolina
Source: NC State University Libraries
Added: October 16, 2021
2002 journal article
DNA binding properties of the yeast Msh2-Msh6 and Mlh1-Pms1 heterodimers
Biological Chemistry, 383(6), 969–975.
Source: ORCID
Added: September 23, 2021
2002 journal article
A minimal exonuclease domain of WRN forms a hexamer on DNA and possesses both 3'-5'exonuclease and 5'-protruding strand endonuclease activities
Biochemistry, 41(9), 2901–2912.
Source: ORCID
Added: September 23, 2021
2002 journal article
Natural diets of vertically migrating zooplankton in the Sargasso Sea
Marine Biology, 141(1), 89–99.
TL;DR:
The species-specific differences in the diets of these three migrating zooplankton suggest that an individual species approach is important in determining how feeding habits affect the structure of pelagic food webs and carbon cycling in the sea.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: August 4, 2021
2002 journal article
Active transport of particulate organic carbon and nitrogen by vertically migrating zooplankton in the Sargasso Sea
Marine Ecology Progress Series, 234, 71–84.
author keywords: zooplankton; vertical migration; gut evacuation rate; gut fluorescence; particulate organic carbon; particulate organic nitrogen; export flux; Sargasso sea; Bermuda Atlantic time-series study (BATS)
TL;DR:
It is estimated that 71 to 85% of the migrant diet originated from non-plant material, which was included in estimates of active POC/PON export, and freshly released feces by migrators at depth could be a valuable food source for mesopelagic organisms.
(via Semantic Scholar)
www.int-res.com (publisher PDF)
UN Sustainable Development Goal Categories
14. Life Below Water
(OpenAlex)
Source: ORCID
Added: August 4, 2021
2002 journal article
The Mouse Genome Database (MGD): the model organism database for the laboratory mouse
Nucleic Acids Research, 30(1), 113–115.
Contributors: J. Blake*, J. Richardson*, C. Bult *, J. Kadin*, J. Eppig*, R. Baldarelli, M. Baya, J. Beal
MeSH headings : Alleles; Animals; Chromosome Mapping; Data Collection; Database Management Systems; Databases, Genetic; Genome; Genotype; Humans; Information Storage and Retrieval; Internet; Mice / genetics; Mutation; Phenotype; Radiation Hybrid Mapping; Rats; Sequence Homology; User-Computer Interface; Vocabulary, Controlled
TL;DR:
Recent integration of large datasets of mouse full-length cDNAs and radiation-hybrid mapped ESTs, the continued development and use of extensive structured vocabularies and the expansion of the representation of phenotypes highlight this year's developments.
(via Semantic Scholar)
Sources: ORCID, Crossref, NC State University Libraries
Added: March 16, 2021
2002 journal article
Time course and manner of Purkinje neuron death following a single ethanol exposure on postnatal day 4 in the developing rat
Neuroscience, 114(2), 327–337.
Contributors: K. Light*, S. Belcher* & D. Pierce*
author keywords: cerebellum; neuronal development; apoptosis; caspase-3; cytochrome c
MeSH headings : Alcohol-Induced Disorders, Nervous System / metabolism; Alcohol-Induced Disorders, Nervous System / pathology; Alcohol-Induced Disorders, Nervous System / physiopathology; Animals; Animals, Newborn; Apoptosis / drug effects; Apoptosis / physiology; Calbindin 1; Calbindins; Caspase 3; Caspases / drug effects; Caspases / metabolism; Cerebellar Cortex / drug effects; Cerebellar Cortex / growth & development; Cerebellar Cortex / pathology; Cytochrome c Group / drug effects; Cytochrome c Group / metabolism; Drug Administration Schedule; Ethanol / toxicity; Female; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / pathology; Fetal Alcohol Spectrum Disorders / physiopathology; Immunohistochemistry; In Situ Nick-End Labeling; Male; Mitochondria / drug effects; Mitochondria / metabolism; Mitochondria / pathology; Nerve Degeneration / chemically induced; Nerve Degeneration / metabolism; Nerve Degeneration / physiopathology; Pregnancy; Prenatal Exposure Delayed Effects; Purkinje Cells / drug effects; Purkinje Cells / metabolism; Purkinje Cells / pathology; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G / metabolism; Time Factors
TL;DR:
The data demonstrate that a single dose of ethanol results in a significant and extensive, lobular dependent loss of Purkinje cells within 24 h after administration, and support the hypothesis that ethanol-induced loss ofPurkinje Cells involves apoptotic mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: March 5, 2021
2002 journal article
Ethanol-induced alterations of neurotrophin receptor expression on Purkinje cells in the neonatal rat cerebellum
Brain Research, 924(1), 71–81.
Contributors: K. Light*, D. Brown*, B. Newton *, S. Belcher* & C. Kane*
author keywords: cerebellum; truncated TrkB; TrkC; ethanol exposure; immunohistochemical
MeSH headings : Alcohol-Induced Disorders, Nervous System / metabolism; Alcohol-Induced Disorders, Nervous System / physiopathology; Animals; Brain-Derived Neurotrophic Factor / metabolism; Cell Differentiation / drug effects; Cell Differentiation / physiology; Cerebellar Cortex / drug effects; Cerebellar Cortex / growth & development; Cerebellar Cortex / pathology; Ethanol / pharmacology; Female; Fetal Alcohol Spectrum Disorders / metabolism; Fetal Alcohol Spectrum Disorders / physiopathology; Immunohistochemistry; Male; Nerve Degeneration / chemically induced; Nerve Degeneration / metabolism; Nerve Degeneration / physiopathology; Nerve Growth Factors / metabolism; Neurotrophin 3 / metabolism; Pregnancy; Purkinje Cells / drug effects; Purkinje Cells / metabolism; Purkinje Cells / pathology; Rats; Rats, Sprague-Dawley; Receptor, trkB / metabolism; Receptor, trkC / metabolism; Receptors, Nerve Growth Factor / drug effects; Receptors, Nerve Growth Factor / metabolism
TL;DR:
Ethanol selectively decreased Purkinje cell expression of TrkB and TrkC receptors following exposures within the vulnerable period (PN4-6), suggesting that ethanol may induce loss ofPurkinje cells by alteration of neurotrophic regulation at this critical stage.
(via Semantic Scholar)
Source: ORCID
Added: March 5, 2021
2002 journal article
Estrogen regulates GFAP-expression in specific subnuclei of the female rat interpeduncular nucleus: A potential role for estrogen receptor β
Brain Research, 958(2), 488–496.
Contributors: A. Zsarnovszky*, T. Smith*, F. Hajos* & S. Belcher*
author keywords: astrocyte; estrogen; estrogen receptor betas; glia, glial fibrillary acidic protein immunohistochemistry; interpeduncular nucleus
MeSH headings : Animals; Estradiol / pharmacology; Estrogen Receptor beta; Estrogens / pharmacology; Female; Glial Fibrillary Acidic Protein / analysis; Glial Fibrillary Acidic Protein / biosynthesis; Mesencephalon / chemistry; Mesencephalon / drug effects; Mesencephalon / metabolism; Ovariectomy; Rats; Rats, Sprague-Dawley; Receptors, Estrogen / analysis; Receptors, Estrogen / physiology
TL;DR:
Results indicate that E(2), in the absence of other ovarian hormones, modulates GFAP-expression within select IPN subnuclei and that these affects are dependent on position along the AP axis and suggest that in the IPN, E( 2) may directly modulateGFAP- expression through ERbeta-mediated mechanisms.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: ORCID
Added: March 5, 2021
2002 journal article
Tailoring the gas-phase dissociation and determining the relative energy of activation for dissociation of 7-deaza purine modified oligonucleotides containing a repeating motif
International Journal of Mass Spectrometry, 219(1), 139–150.
TL;DR:
7-Deaza purine modified oligonucleotides with a repeating motif have been sequenced by slow heating methods illustrating the ability to alter the preferred unimolecular decomposition pathway and limited the number of product ions per repeat unit resulting in an increased signal-to-noise ratio for the tandem mass spectrometry data.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
7. Affordable and Clean Energy
(OpenAlex)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021
2002 journal article
Evaluation of sample preparation techniques for mass measurements of PCR products using ESI-FT-ICR mass spectrometry
Journal of the American Society for Mass Spectrometry, 13(4), 338–344.
MeSH headings : 2-Propanol / chemistry; 2-Propanol / isolation & purification; DNA / chemistry; Ethanol / chemistry; Ethanol / isolation & purification; Indicators and Reagents; Microdialysis; Polymerase Chain Reaction / methods; Solvents; Spectrometry, Mass, Electrospray Ionization / methods
TL;DR:
Alternative cleanup techniques that are compatible with automation are explored here with the intent of expanding the bottleneck that exists between the production of PCR products and analysis by electrospray ionization mass spectrometry (ESI-MS).
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 27, 2021
2002 journal article
In celebration of the 70th birthday of Dr David M. Hercules
Analytical and Bioanalytical Chemistry, 373(7), 517–518.
MeSH headings : Chemistry, Analytic / history; History, 20th Century; History, 21st Century; Spectrum Analysis; United States
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2002 journal article
Memoirs, Hercules lineage, students, visiting scientists and staff
Analytical and Bioanalytical Chemistry, 373(7), 669–675.
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2002 journal article
Dual-micro-ESI source for precise mass determination on a quadrupole time-of-flight mass spectrometer for genomic and proteomic applications
Analytical and Bioanalytical Chemistry, 373(7), 538–546.
author keywords: electrospray; time-of-flight; mass spectrometry; internal calibration; accurate mass
MeSH headings : Amino Acid Sequence; Calibration; Caseins / chemistry; Caseins / metabolism; Genomics / methods; Ions; Molecular Sequence Data; Phosphoproteins / chemistry; Phosphoproteins / metabolism; Polymerase Chain Reaction; Proteome; Sensitivity and Specificity; Sequence Analysis, Protein; Spectrometry, Mass, Electrospray Ionization / instrumentation; Spectrometry, Mass, Electrospray Ionization / methods; Trypsin / metabolism
TL;DR:
In this report, the dual-sprayer is demonstrated in the negative-ion mode for internal calibration of polymerase chain reaction (PCR) amplicons generated from synthetic and genomic templates as well as a proteolytic digest of a naturally phosphorylated protein.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2002 journal article
Gas-Phase Ion Unimolecular Dissociation for Rapid Phosphopeptide Mapping by IRMPD in a Penning Ion Trap: An Energetically Favored Process
Journal of the American Chemical Society, 124(23), 6546–6547.
MeSH headings : Amino Acid Sequence; Lasers; Peptide Mapping / methods; Phosphopeptides / chemistry; Receptor, Insulin / chemistry; Spectrometry, Mass, Electrospray Ionization / methods; Spectroscopy, Fourier Transform Infrared / methods; Thermodynamics
TL;DR:
This research demonstrates that the energy of activation for dissociation of the phosphopeptides is lower than that of the unmodified analogues providing the basis for the success of this technique, and IRMPD of ions in a Penning ion trap is an ideal platform for rapid phosphopeptic mapping.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
2002 journal article
Solution composition and thermal denaturation for the production of single-stranded PCR amplicons: Piperidine-induced destabilization of the DNA duplex?
Journal of the American Society for Mass Spectrometry, 13(3), 232–240.
MeSH headings : Cyclotrons; DNA / chemistry; DNA / drug effects; DNA, Single-Stranded / chemistry; Fourier Analysis; Hot Temperature; Humans; Nucleic Acid Denaturation / drug effects; Oligonucleotides / chemistry; Piperidines / pharmacology; Reverse Transcriptase Polymerase Chain Reaction; Spectrometry, Mass, Electrospray Ionization
TL;DR:
The volatile base piperidine, present at 20 mM concentrations in the electrospray solution, was found to play a critical role in the formation of single-stranded species at the higher aqueous percentages and a duplex destabilization mechanism has been proposed.
(via Semantic Scholar)
Sources: Crossref, NC State University Libraries
Added: February 12, 2021
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