Center for Human Health and the Environment

Works Published in 2020

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Displaying works 1 - 20 of 260 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 journal article

Efficient sub-15 nm cubic-phase core/shell upconversion nanoparticles as reporters for ensemble and single particle studies

Nanoscale.

TL;DR: The results underline the potential applicability of the described sub-15 nm cubic-phase core/shell UCNPs for ensemble- and single particle-level bioimaging. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: ORCID
Added: February 1, 2024

2020 journal article

Social approach and social vigilance are differentially regulated by oxytocin receptors in the nucleus accumbens

Neuropsychopharmacology, 45(9), 1423–1430.

By: A. Williams*, N. Duque-Wilckens*, S. Ramos-Maciel*, K. Campi*, S. Bhela*, C. Xu*, K. Jackson*, B. Chini*, P. Pesavento*, B. Trainor*

TL;DR: It is suggested that OTR in the NAc differentially modulate social approach and social vigilance, primarily through an OTR-Gq mechanism. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

2020 journal article

Histamine-dependent interactions between mast cells, glia, and neurons are altered following early-life adversity in mice and humans

American Journal of Physiology-Gastrointestinal and Liver Physiology, 319(6), G655–G668.

By: J. McClain*, E. Mazzotta*, N. Maradiaga*, N. Duque-Wilckens*, I. Grants*, A. Robison*, F. Christofi*, A. Moeser*, B. Gulbransen*

TL;DR: Early life stress alters interactions between enteric glia and mast cells that are mediated by histamine, and this mechanism could contribute to enteric neuroplasticity driven by early life adversity. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

2020 journal article

Extrahypothalamic oxytocin neurons drive stress-induced social vigilance and avoidance

Proceedings of the National Academy of Sciences, 117(42), 26406–26413.

By: N. Duque-Wilckens*, L. Torres*, S. Yokoyama*, V. Minie*, A. Tran*, S. Petkova*, R. Hao*, S. Ramos-Maciel* ...

UN Sustainable Development Goal Categories
10. Reduced Inequalities (OpenAlex)
Source: ORCID
Added: January 28, 2024

2020 journal article

Androgen-Dependent Excitability of Mouse Ventral Hippocampal Afferents to Nucleus Accumbens Underlies Sex-Specific Susceptibility to Stress

Biological Psychiatry, 87(6), 492–501.

TL;DR: A circuit-specific sex difference in vHPC-NAc neurons that is dependent on testosterone and causes susceptibility to stress in female mice is demonstrated, providing a substantive mechanism linking gonadal hormones to cellular excitability and anhedonia-a key feature in depressive states. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: January 28, 2024

2020 article

Neural Network Organization for Courtship Song Feature Detection inDrosophila

Baker, C. A., McKellar, C., Nern, A., Dorkenwald, S., Pacheco, D. A., Pang, R., … Murthy, M. (2020, October 9).

By: C. Baker*, C. McKellar*, A. Nern*, S. Dorkenwald*, D. Pacheco, R. Pang, N. Eckstein, J. Funke, B. Dickson*, M. Murthy*

Source: ORCID
Added: November 14, 2023

2020 journal article

Rapid Characterization of Per- and Polyfluoroalkyl Substances (PFAS) by Ion Mobility Spectrometry–Mass Spectrometry (IMS-MS)

Analytical Chemistry, 92(6), 4427–4435.

MeSH headings : Hydrocarbons, Fluorinated / analysis; Ion Mobility Spectrometry; Mass Spectrometry; Molecular Structure; Polymers / analysis
TL;DR: Results from this study show that the IMS separation provides novel information to support traditional LC-MS PFAS analyses and will greatly benefit the evaluation of unknown pollutants in future environmental studies. (via Semantic Scholar)
Source: ORCID
Added: September 9, 2023

2020 report

Complete list of requirements for a nano-specific risk governance framework

[Deliverable]. caLIBRAte European project, Horizon 2020 research and innovation program.

By: K. Jensen, A. Porcari, L. Pizzol, S. Kelly, M. Bakker, D. Spurgeon, K. Grieger, S. Chakravarty

Source: NC State University Libraries
Added: July 2, 2023

2020 chapter

Nanomaterials: Regulation and Risk Assessment

In Managing Human and Social Systems (2nd ed.). Boca Raton: CRC Press.

By: S. Hansen, K. Grieger & A. Baun

Source: NC State University Libraries
Added: July 2, 2023

2020 journal article

Pandemics Call for Systems Approaches to Research and Funding

Issues in Science and Technology. https://issues.org/pandemics-call-for-systems-approaches/

By: C. Cummings, J. Kuzma, K. Grieger & Z. Brown

Source: NC State University Libraries
Added: July 2, 2023

2020 journal article

Surveillance system assessment in Guinea: Training needed to strengthen data quality and analysis, 2016

PLOS ONE, 15(6), e0234796.

By: D. Collins*, S. Rhea*, B. Diallo*, M. Bah*, F. Yattara, R. Keleba*, P. MacDonald*

Ed(s): J. Schieffelin

MeSH headings : Community Health Planning / statistics & numerical data; Data Accuracy; Disease Outbreaks / statistics & numerical data; Epidemiological Monitoring; Guinea; Hemorrhagic Fever, Ebola / epidemiology; Humans; Public Health / education; Research Design
TL;DR: Assessment findings suggest low sensitivity of the case-based disease surveillance system in Boffa, and recommend additional training and support to improve surveillance data quality and enhance Guinean public health workforce capacity to use these data. (via Semantic Scholar)
Source: ORCID
Added: May 24, 2023

2020 journal article

Modeling Infectious Diseases in Healthcare Network (MInD-Healthcare) Framework for Describing and Reporting Multidrug-resistant Organism and Healthcare-Associated Infections Agent-based Modeling Methods

Clinical Infectious Diseases, 3.

MeSH headings : Communicable Diseases / epidemiology; Delivery of Health Care; Drug Resistance, Multiple, Bacterial; Humans; Reproducibility of Results; Systems Analysis
TL;DR: The MInD-Healthcare framework provides a standardized way of describing and reporting models thereby instilling confidence in the reproducibility and generalizability of such models and will improve the quality of evidence generated utilizing these models. (via Semantic Scholar)
Source: ORCID
Added: May 24, 2023

2020 journal article

Mitigating the Risk of Infectious Diseases Among Rural Drug Users in Western North Carolina: Results of the Southern Appalachia Test, Link, Care (SA‐TLC) Health Care Provider Survey

The Journal of Rural Health, 36(2), 208–216.

MeSH headings : Drug Users; HIV Infections / epidemiology; HIV Infections / prevention & control; Health Personnel; Hepatitis C / epidemiology; Hepatitis C / prevention & control; Humans; North Carolina / epidemiology; Opioid-Related Disorders / epidemiology; Prevalence; Risk Factors; Surveys and Questionnaires
TL;DR: The authors' findings provide insights to inform health infrastructure improvement and to inform strategies for preventing injection drug use (IDU)-associated outbreaks of bloodborne infectious diseases in southern Appalachia. (via Semantic Scholar)
Sources: ORCID, Crossref
Added: May 24, 2023

2020 journal article

Contextual, Social and Epidemiological Characteristics of the Ebola Virus Disease Outbreak in Likati Health Zone, Democratic Republic of the Congo, 2017

Frontiers in Public Health, 8.

By: K. Grimes*, B. Ngoyi*, K. Stolka*, J. Hemingway-Foday*, L. Lubula*, M. Mossoko*, A. Okitandjate*, P. MacDonald* ...

MeSH headings : Democratic Republic of the Congo / epidemiology; Disease Outbreaks; Ebolavirus; Epidemics; Hemorrhagic Fever, Ebola / diagnosis; Humans
TL;DR: The role that several factors played in the trajectory of the epidemic, including traditional healers, insufficient knowledge of epidemiological case definitions, a lack of community-based surveillance systems and tools, and remote geography are discussed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: ORCID, Crossref
Added: May 24, 2023

2020 journal article

Modeling inpatient and outpatient antibiotic stewardship interventions to reduce the burden of Clostridioides difficile infection in a regional healthcare network

PLOS ONE, 15(6), e0234031.

By: S. Rhea*, K. Jones*, S. Endres-Dighe*, B. Munoz*, D. Weber*, R. Hilscher*, J. MacFarquhar*, E. Sickbert-Bennett* ...

Ed(s): M. Tizzoni

MeSH headings : Antimicrobial Stewardship / statistics & numerical data; Clostridioides difficile / physiology; Clostridium Infections / prevention & control; Cross Infection / prevention & control; Drug Prescriptions / statistics & numerical data; Humans; Inpatients / statistics & numerical data; Models, Statistical; Outpatients / statistics & numerical data; Risk
TL;DR: The results support the potential importance of LTCF and outpatient antibiotic stewardship efforts on network CDI burden and add to the evidence that a coordinated approach to antibiotics stewardship across multiple facilities, including inpatient and outpatient settings, within a regional healthcare network could be an effective strategy to reduce networkCDI burden. (via Semantic Scholar)
Source: ORCID
Added: May 24, 2023

2020 conference paper

Assessing Strain On Hospital Capacity During A Localized Epidemic Using A Calibrated Hospitalization Microsimulation

2020 Winter Simulation Conference (WSC).

TL;DR: An existing hospitalization microsimulation of North Carolina is adapted to assess the impact of a localized epidemic of a fictitious pathogen on inpatient hospital bed availability in the same locale to explore how variability in the duration and severity of an epidemic affects hospital capacity in different North Carolina counties. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: May 24, 2023

2020 journal article

Publisher Correction: Exposure to Oil and Hypoxia Results in Alterations of Immune Transcriptional Patterns in Developing Sheepshead Minnows (Cyprinodon variegatus) (Scientific Reports, (2020), 10, 1, (1684), 10.1038/s41598-020-58171-8)

Scientific Reports, 10(1).

By: M. Rodgers*, D. Simning*, M. Sepúlveda*, S. De Guise*, T. Bosker* & R. Griffitt*

Contributors: M. Rodgers*, D. Simning*, M. Sepúlveda*, S. De Guise*, T. Bosker* & R. Griffitt*

TL;DR: An amendment to this paper has been published and can be accessed via a link at the top of the paper. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: ORCID
Added: April 6, 2023

2020 journal article

Exposure to Oil and Hypoxia Results in Alterations of Immune Transcriptional Patterns in Developing Sheepshead Minnows (Cyprinodon variegatus)

Scientific Reports, 10(1).

By: M. Rodgers*, D. Simning*, M. Sepúlveda*, S. De Guise*, T. Bosker* & R. Griffitt*

Contributors: M. Rodgers*, D. Simning*, M. Sepúlveda*, S. De Guise*, T. Bosker* & R. Griffitt*

TL;DR: It is suggested that timing of exposure to oil and/or hypoxia matters, and the need to further investigate the impacts of multiple stressors on immune system development in early life stage fishes is underscored. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: April 6, 2023

2020 journal article

Faecal contamination of the environment and child health: a systematic review and individual participant data meta-analysis

The Lancet Planetary Health, 4(9), e405–e415.

Contributors: A. Ercumen n

MeSH headings : Child; Child Health; Diarrhea / epidemiology; Diarrhea / microbiology; Environmental Microbiology; Family Characteristics; Feces / microbiology; Hand / microbiology; Humans; Odds Ratio
TL;DR: Although summary measures from individual studies often report little or no effect of measured faecal contamination on child health, this multi-study IPD analysis indicates that household faecic bacteria concentrations are associated with important adverse health outcomes in young children. (via Semantic Scholar)
Source: ORCID
Added: September 16, 2022

2020 journal article

Source: ORCID
Added: June 14, 2022

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