Center for Human Health and the Environment

Works Published in 2021

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Displaying works 1 - 20 of 263 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2021 journal article

Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors

Communications Biology, 4(1).

TL;DR: It is shown loss of ASH1L in the developing mouse brain is sufficient to cause multiple developmental defects, core autistic-like behaviors, and impaired cognitive memory, and potential molecular mechanisms linking Ash1L mutations to brain functional abnormalities are established. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

2021 journal article

Enriched laboratory housing increases sensitivity to social stress in female California mice (Peromyscus californicus)

Applied Animal Behaviour Science, 241, 105381.

By: V. Minie*, R. Petric*, S. Ramos-Maciel*, E. Wright*, B. Trainor* & N. Duque-Wilckens*

TL;DR: Assessing how different housing systems can affect California mouse behavior both in the home cage as well as the open field and social interaction tests before and after social defeat stress suggests that increasing social and environmental complexity affects home cage behaviors in male and female California mice without interfering with, but rather increasing the magnitude of, the effects of defeat stress on theopen field andsocial interaction tests. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

2021 journal article

Convergent neuroendocrine mechanisms of social buffering and stress contagion

Hormones and Behavior, 129, 104933.

By: N. Peen*, N. Duque-Wilckens* & B. Trainor*

TL;DR: The extent to which the neuropeptides corticotropin releasing hormone and oxytocin are involved in contagion and stress buffering is considered and the importance that frontal cortical areas such as the anterior cingulate cortex and infralimbic cortex play is assessed. (via Semantic Scholar)
Source: ORCID
Added: January 28, 2024

2021 journal article

Looking for Proof in the Wrong Generation?

Cancer Epidemiology, Biomarkers & Prevention, 30(8), 1459–1461.

By: S. Fenton* & A. Boyles*

TL;DR: The article in this issue “Grandmaternal Perinatal Serum DDT in Relation to Granddaughter Early Menarche and Adult Obesity: Three Generations in the Child Health and Development Studies Cohort,” by Cirillo and colleagues, is the first to report multigenerational health effects in granddaughters stemming from early life exposures to the pesticide o,p'-DDT in grandmothers. (via Semantic Scholar)
Source: ORCID
Added: October 28, 2023

2021 journal article

Latent, sex-specific metabolic health effects in CD-1 mouse offspring exposed to PFOA or HFPO-DA (GenX) during gestation

Emerging Contaminants, 7, 219–235.

TL;DR: Prenatal exposure to 1mg/kg GenX and 1 mg/kg PFOA induces adverse metabolic outcomes in adult mice that are diet- and sex-dependent, suggesting that placental and potentially lactational transfer are important exposure routes for GenX. (via Semantic Scholar)
UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: October 28, 2023

2021 journal article

Response to “Comment on Scientific Basis for Managing PFAS as a Chemical Class”

Response to “Comment on Scientific Basis for Managing PFAS as a Chemical Class.” Environmental Science & Technology Letters, 8(2), 195–197.

Source: ORCID
Added: September 9, 2023

2021 journal article

Longitudinal assessment of point‐of‐use carbon filters for removal of per‐ and polyfluoroalkyl substances from private well water

AWWA Water Science, 3(6).

By: R. Mulhern*, N. Bynum*, C. Liyanapatirana*, N. DeStefano n, D. Knappe n & J. Gibson*

UN Sustainable Development Goal Categories
6. Clean Water and Sanitation (OpenAlex)
Source: ORCID
Added: September 9, 2023

2021 journal article

Pharmacist attitudes and provision of harm reduction services in North Carolina: an exploratory study

Harm Reduction Journal, 18(1).

MeSH headings : Attitude of Health Personnel; Drug Users; Harm Reduction; Humans; North Carolina; Pharmacists; Substance Abuse, Intravenous
TL;DR: Although most pharmacies distributed naloxone and sold non-prescription syringes, pharmacy store policies and personal beliefs inhibited nalOXone and non- Prescription syringe dispensing, particularly for rural NC residents. (via Semantic Scholar)
Source: ORCID
Added: May 24, 2023

2021 article

North Carolina COVID-19 Agent-Based Model Framework for Hospitalization Forecasting Overview, Design Concepts, and Details Protocol

(2021, June 8).

Sarah Rhea

Source: ORCID
Added: May 24, 2023

2021 chapter

5 Risk screening tools for engineered nanomaterials

In Ethics in Nanotechnology (pp. 89–108).

By: K. Grieger*, P. Isigonis, R. Franken, H. Wigger, N. Bossa, G. Janer, T. Rycroft, A. Kennedy, S. Hansen

Sources: Crossref, ORCID
Added: May 22, 2023

2021 article

Isolating and growing fibroblast cells from threespine stickleback (Gasterosteus aculeatus) v2

Le, G. Q., Steinel, N., Fuess, L., Rodgers, M., & Bolnick, D. (2021, December 13). (Vol. 12). Vol. 12.

TL;DR: This protocol goes through the process of isolating and growing fibroblast cells from threespine stickleback and shows the importance of knowing the carrier and removal status of canine coronavirus. (via Semantic Scholar)
Source: ORCID
Added: April 6, 2023

2021 journal article

The impact of salinity and dissolved oxygen regimes on transcriptomic immune responses to oil in early life stage Fundulus grandis

Comparative Biochemistry and Physiology - Part D: Genomics and Proteomics, 37.

By: M. Rodgers*, J. Serafin*, M. Sepúlveda* & R. Griffitt*

Contributors: M. Rodgers*, J. Serafin*, M. Sepúlveda* & R. Griffitt*

MeSH headings : Animals; Fundulidae / genetics; Fundulidae / growth & development; Fundulidae / immunology; Gene Expression Regulation, Developmental / drug effects; Immunity / drug effects; Larva / drug effects; Larva / genetics; Larva / growth & development; Larva / immunology; Oxygen / immunology; Oxygen / metabolism; Petroleum Pollution / adverse effects; Salinity; Transcriptome / drug effects; Water Pollutants, Chemical / adverse effects
TL;DR: Examination of transcriptional patterns of immune genes and pathways in Fundulus grandis larvae to various oil, salinity, and DO regimes suggests that oil under certain environmental conditions has the potential to further modulate immune-related genes, pathways, and responses in fish. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: April 6, 2023

2021 journal article

Isolating and growing fibroblast cells from threespine stickleback (Gasterosteus aculeatus)

Protocols.io.

By: M. Rodgers*, L. Fuess & D. Bolnick

Source: ORCID
Added: April 6, 2023

2021 journal article

Characterizing transcriptomic responses of southern flounder (Paralichthys lethostigma) chronically exposed to Deepwater Horizon oiled sediments

Aquatic Toxicology, 230.

By: M. Rodgers*, T. Sherwood*, A. Tarnecki*, R. Griffitt* & D. Wetzel*

Contributors: M. Rodgers*, T. Sherwood*, A. Tarnecki*, R. Griffitt* & D. Wetzel*

MeSH headings : Animals; Computational Biology; Flounder / genetics; Geologic Sediments / chemistry; Gills / chemistry; Gills / drug effects; Gulf of Mexico; Liver / chemistry; Liver / drug effects; Petroleum / toxicity; Petroleum Pollution / adverse effects; Transcriptome / drug effects; Water Pollutants, Chemical / toxicity
TL;DR: It is demonstrated that liver and gill tissues from southern flounder were differentially altered by Deepwater Horizon oiled sediment exposure and that a 30-day recovery period after exposure substantially shifted gene expression and canonical pathway profiles. (via Semantic Scholar)
Source: ORCID
Added: April 6, 2023

2021 journal article

Galaxolide and tonalide modulate neuroendocrine activity in marine species from two taxonomic groups

Environmental Research.

By: F. Ehiguese*, M. Rodgers*, C. Araújo*, R. Griffitt* & M. Martin-Diaz*

MeSH headings : Adult; Benzopyrans; Ecosystem; Humans; Tetrahydronaphthalenes / analysis; Tetrahydronaphthalenes / toxicity; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
TL;DR: The results of this study demonstrate that HHCB and AHTN might pose neurotoxic and endocrine disrupting effects in coastal ecosystems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: April 6, 2023

2021 journal article

Effects of polycyclic aromatic hydrocarbons and abiotic stressors on Fundulus grandis cardiac transcriptomics

Science of the Total Environment, 752.

By: E. Allmon*, J. Serafin*, S. Chen*, M. Rodgers*, R. Griffitt*, T. Bosker*, S. Guise*, M. Sepúlveda*

Contributors: E. Allmon*, J. Serafin*, S. Chen*, M. Rodgers*, R. Griffitt*, T. Bosker*, S. Guise*, M. Sepúlveda*

MeSH headings : Animals; Fundulidae / genetics; Petroleum; Petroleum Pollution / adverse effects; Polycyclic Aromatic Hydrocarbons / analysis; Polycyclic Aromatic Hydrocarbons / toxicity; Transcriptome; Water Pollutants, Chemical / analysis; Water Pollutants, Chemical / toxicity
TL;DR: Exposure to oil and abiotic stressors appear to reduce development of the systemic vasculature as well as strongly impact the cardiac musculature through cardiomyocyte proliferation resulting in inhibited cardiac function and modulated blood pressure maintenance in developing Fundulus grandis larvae. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: April 6, 2023

2021 journal article

Characterization of the differential expressed genes and transcriptomic pathway analysis in the liver of sub-adult red drum (Sciaenops ocellatus) exposed to Deepwater Horizon chemically dispersed oil

Ecotoxicology and Environmental Safety, 214.

By: T. Sherwood*, M. Rodgers*, A. Tarnecki* & D. Wetzel*

Contributors: T. Sherwood*, M. Rodgers*, A. Tarnecki* & D. Wetzel*

MeSH headings : Animals; Fishes; Gene Expression Profiling; Gulf of Mexico; Lipids; Liver / chemistry; Perciformes / physiology; Petroleum / toxicity; Petroleum Pollution / analysis; Transcriptome / physiology; Water / analysis; Water Pollutants, Chemical / toxicity
TL;DR: It is indicated that CEWAF exposure significantly affects gene expression and alters signaling of biological pathways important in detoxification, immunity, and normal cellular physiology, which can have potential consequences on organismal fitness. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: ORCID
Added: April 6, 2023

2021 journal article

Household finished flooring and soil-transmitted helminth and Giardia infections among children in rural Bangladesh and Kenya: a prospective cohort study

The Lancet Global Health, 9(3), e301–e308.

Contributors: A. Ercumen n

MeSH headings : Adolescent; Bangladesh / epidemiology; Child; Child, Preschool; Developing Countries; Enzyme-Linked Immunosorbent Assay; Feces / parasitology; Female; Floors and Floorcoverings / methods; Giardiasis / epidemiology; Giardiasis / transmission; Helminthiasis / epidemiology; Helminthiasis / transmission; Housing; Humans; Kenya / epidemiology; Male; Prevalence; Prospective Studies; Real-Time Polymerase Chain Reaction; Rural Population; Soil / parasitology
Source: ORCID
Added: September 16, 2022

2021 journal article

Altered glucuronidation deregulates androgen dependent response profiles and signifies castration resistance in prostate cancer

Oncotarget, 12(19), 1886–1902.

By: B. Zimmer n, M. Howell*, L. Ma n, J. Enders n, D. Lehman n, E. Corey*, J. Barycki n, M. Simpson n

TL;DR: A role for UGDH in androgen responsiveness and a target for therapeutic strategies in advanced prostate cancer is supported by a comparison of protein and metabolite levels relevant to the glucuronidation pathway in patient-derived xenograft models paired with isogenic counterparts selected in vivo for castration resistant prostate cancer recurrence. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Source: ORCID
Added: July 16, 2022

2021 journal article

Gestational Phthalate Exposure and Preschool Attention Deficit Hyperactivity Disorder in Norway

ENVIRONMENTAL EPIDEMIOLOGY, 5(4).

By: E. Kamai*, G. Villanger*, R. Nethery*, C. Thomsen*, A. Sakhi*, S. Drover*, J. Hoppin n, G. Knudsen* ...

author keywords: phthalates; ADHD; Attention Deficit Hyperactivity Disorder; biomarkers; prenatal; gestational; MoBa; The Norwegian Mother; Father and Child Cohort Study
TL;DR: Results suggest gestational phthalate exposure may impact the behavior of children as young as 3 years, and boys, but not girls, mono-n-butyl phthalates exposure was associated with increased odds of ADHD. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (OpenAlex)
Sources: Web Of Science, ORCID
Added: May 16, 2022

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