Works Published in 2010
Displaying all 16 works
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 chapter
Primary myocardial disease in the dog
In Textbook of Veterinary Internal Medicine (7th ed., pp. 1320–1328). Philadelphia: WB Saunders.
Source: NC State University Libraries
Added: October 10, 2020
2010 chapter
Genetic screening of familial hypertrophic cardiomyopathy
In Consultations in Feline Internal Medicine (pp. 406–408). Philadelphia: WB Saunders.
Source: NC State University Libraries
Added: October 10, 2020
2010 journal article
W1250 Genome-Wide Association Scan Reveals Polymorphisms in the P67phox Subunit (Ncf2) of the NADPH Oxidase Complex in Boxer Dogs With Adherent and Invasive E.Coli-Associated Granulomatous Colitis: A Potential Model of Chronic Granulomatous Disease
Gastroenterology, 138(5), S-683.
Sources: Crossref, ORCID
Added: March 8, 2020
2010 journal article
Genetics of Cardiac Disease in the Small Animal Patient
Veterinary Clinics of North America: Small Animal Practice, 40(4), 701–715.
author keywords: Familial; Mutation; Cardiomyopathy; Congenital heart disease
MeSH headings : Animals; Breeding; Cat Diseases / genetics; Cat Diseases / prevention & control; Cats; Dog Diseases / genetics; Dog Diseases / prevention & control; Dogs; Female; Genetic Diseases, Inborn / prevention & control; Genetic Diseases, Inborn / veterinary; Genetic Predisposition to Disease; Heart Diseases / genetics; Heart Diseases / prevention & control; Heart Diseases / veterinary; Male; Selection, Genetic
TL;DR:
Common forms of inheritance for veterinary diseases include autosomal recessive, autosomal dominant, X-linked recessives, and polygenic and their possible involvement in cardiac disease in small animals are discussed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: March 8, 2020
2010 journal article
Differential methylation of CpG sites in two isoforms of myosin binding protein C, an important hypertrophic cardiomyopathy gene
Environmental and Molecular Mutagenesis, 52(2), 161–164.
author keywords: CpG; cardiac; deamination; cardiomyopathy
MeSH headings : Cardiomegaly / genetics; Cardiomegaly / metabolism; Carrier Proteins / genetics; CpG Islands; DNA Methylation; Exons; Humans; Muscle Proteins / genetics; Muscle Proteins / metabolism; Muscle, Skeletal / metabolism; Protein Isoforms
TL;DR:
It is determined that although the mean number of CG sites was identical within the coding region of each gene, the mean methylation level of CpGs was significantly higher in MYBPC3 thanMYBPC2 (P < 0.0001).
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: November 16, 2019
2010 journal article
Genome-wide association identifies a deletion in the 3′ untranslated region of Striatin in a canine model of arrhythmogenic right ventricular cardiomyopathy
Human Genetics, 128(3), 315–324.
MeSH headings : 3' Untranslated Regions; Animals; Arrhythmogenic Right Ventricular Dysplasia / genetics; Arrhythmogenic Right Ventricular Dysplasia / metabolism; Calmodulin-Binding Proteins / genetics; Chromosome Mapping; DNA Mutational Analysis; Disease Models, Animal; Dogs; Genome-Wide Association Study; Humans; Membrane Proteins / genetics; Microscopy, Fluorescence; Myocardium / metabolism; Nucleic Acid Conformation; Polymorphism, Single Nucleotide; RNA, Messenger / chemistry; RNA, Messenger / genetics; RNA, Messenger / metabolism; Sequence Deletion
TL;DR:
It is suggested that Striatin may serve as a novel candidate gene for human ARVC, based on the fact that dogs that were homozygous for the deletion had a more severe form of disease based on a significantly higher number of ventricular premature complexes.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: November 16, 2019
2010 journal article
Correlation of heart rate to body weight in apparently normal dogs
Journal of Veterinary Cardiology, 12(2), 107–110.
MeSH headings : Animals; Atrial Premature Complexes / diagnostic imaging; Atrial Premature Complexes / physiopathology; Atrial Premature Complexes / veterinary; Body Weight / physiology; Dogs / anatomy & histology; Dogs / physiology; Electrocardiography, Ambulatory / veterinary; Heart Rate / physiology; Ultrasonography; Ventricular Premature Complexes / diagnostic imaging; Ventricular Premature Complexes / physiopathology; Ventricular Premature Complexes / veterinary
TL;DR:
The present study does not support a correlation between heart rate and body weight in apparently healthy dogs.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: November 16, 2019
2010 journal article
Ambulatory electrocardiographic evaluation of clinically normal adult Boxers
Journal of the American Veterinary Medical Association, 236(4), 430–433.
MeSH headings : Animals; Cross-Sectional Studies; Dog Diseases / diagnosis; Dogs; Electrocardiography, Ambulatory / veterinary; Female; Male; Ventricular Premature Complexes / veterinary
TL;DR:
Clinically normal adult Boxers generally had < 91 VPCs/24 h and an arrhythmia grade < 2 and may have represented dogs with arrhythmogenic right ventricular cardiomyopathy or other disease processes that could have resulted in the development of ventricular arrh rhythmias.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Sources: Crossref, ORCID
Added: November 16, 2019
2010 journal article
Evaluation of a Midhumeral Block of the Radial, Ulnar, Musculocutaneous and Median (RUMM Block) Nerves for Analgesia of the Distal Aspect of the Thoracic Limb in Dogs
Veterinary Surgery, 39(7), 785–796.
MeSH headings : Anesthetics, Local / administration & dosage; Anesthetics, Local / therapeutic use; Animals; Brachial Plexus / drug effects; Bupivacaine / administration & dosage; Bupivacaine / therapeutic use; Dogs; Forelimb / innervation; Forelimb / surgery; Humerus; Median Nerve / drug effects; Musculocutaneous Nerve / drug effects; Nerve Block / methods; Nerve Block / veterinary; Radial Nerve / drug effects; Ulnar Nerve / drug effects
TL;DR:
Sensory thresholds were significantly increased over baseline measurements when compared with control limbs for all nerves, and RUMM block may be an effective technique to provide adjunctive analgesia for dogs undergoing surgery of the distal aspect of the thoracic limb.
(via Semantic Scholar)
Sources: Crossref, Web Of Science
Added: August 6, 2018
2010 journal article
Outcome assessment of a computer-animated model for learning about the regulation of glomerular filtration rate
ADVANCES IN PHYSIOLOGY EDUCATION, 34(2), 97–105.
author keywords: medical education; veterinary; interactive; renal physiology
MeSH headings : Computer Simulation; Education, Veterinary / methods; Glomerular Filtration Rate / physiology; Humans; Physiology / education; Problem-Based Learning / methods
TL;DR:
It is suggested that the animated model is a useful, effective, and well-received tool for learning and creating a visual memory of the regulatory mechanisms of GFR.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Temporal Changes in Expression of FoxA1 and Wnt7A in Isolated Adult Human Alveolar Epithelial Cells Enhanced by Heparin
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 293(6), 938–946.
author keywords: beta-catenin; differentiation; heparin; sulfated extracellular matrices
MeSH headings : Adult; Anticoagulants / physiology; Biomarkers / metabolism; Cell Differentiation / drug effects; Cell Differentiation / physiology; Cell Line; Cell Separation; Cells, Cultured; Heparin / physiology; Hepatocyte Nuclear Factor 3-alpha / biosynthesis; Hepatocyte Nuclear Factor 3-alpha / genetics; Humans; Pulmonary Alveoli / cytology; Pulmonary Alveoli / drug effects; Pulmonary Alveoli / metabolism; Respiratory Mucosa / cytology; Respiratory Mucosa / drug effects; Respiratory Mucosa / metabolism; Time Factors; Wnt Proteins / biosynthesis; Wnt Proteins / genetics; beta Catenin / biosynthesis; beta Catenin / genetics
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Developmental Profile of Claudin-3,-5, and-16 Proteins in the Epithelium of Chick Intestine
ANATOMICAL RECORD-ADVANCES IN INTEGRATIVE ANATOMY AND EVOLUTIONARY BIOLOGY, 293(7), 1175–1183.
author keywords: claudin proteins; tight junctions; intestine; goblet cells; chick embryo
MeSH headings : Animals; Chick Embryo; Chickens / genetics; Chickens / growth & development; Chickens / metabolism; Claudin-3; Claudins / analysis; Claudins / genetics; Claudins / metabolism; Immunohistochemistry; Intestinal Mucosa / embryology; Intestinal Mucosa / growth & development; Intestinal Mucosa / metabolism; Membrane Proteins / analysis; Membrane Proteins / genetics; Membrane Proteins / metabolism; RNA, Messenger / metabolism; Tight Junctions / chemistry; Tight Junctions / metabolism
TL;DR:
Results of this work indicate that the claudin proteins assume their final locations within the epithelium around the time of hatching, suggesting that in addition to their known barrier and fence functions within tight junctions, these claudins may have additional roles in the differentiation and/or physiological function of chick intestine.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Pharmacokinetics of radiolabeled tungsten (W-188) in male Sprague-Dawley rats following acute sodium tungstate inhalation
INHALATION TOXICOLOGY, 22(1), 69–76.
author keywords: Inhalation; kinetics; tungsten
MeSH headings : Administration, Inhalation; Aerosols; Animals; Inhalation Exposure; Male; Metabolic Clearance Rate; Models, Biological; Radioisotopes; Rats; Rats, Sprague-Dawley; Tissue Distribution; Tungsten Compounds / pharmacokinetics
TL;DR:
Evaluated the pharmacokinetics of inhaled tungstate (WO4) in rats found the kidney, adrenal, spleen, femur, lymph nodes, and brain continued to accumulate small amounts of tungsten as reflected by tissue:blood activity ratios that increased throughout the 21-day period.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 article
Multi-Dose-Route, Multi-Species Pharmacokinetic Models for Manganese and Their Use in Risk Assessment
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, Vol. 73, pp. 217–234.
MeSH headings : Animals; Dose-Response Relationship, Drug; Drug Administration Routes; Haplorhini; Humans; Manganese / adverse effects; Manganese / pharmacokinetics; Models, Biological; Nutritional Requirements; Rats; Risk Assessment; Tissue Distribution
TL;DR:
This study reviews the development of the Mn PBPK models, reassesses the previously identified data needs, and details potential uses of these models in risk assessment of Mn.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Clinical findings and outcomes of ulcerative keratomycosis in 30 horses in the mid-Atlantic United States (2006-2007)
Equine Veterinary Education, 22(1), 31–39.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Preparation of Canine and Feline Cadavers for Surgical Laboratories
VETERINARY SURGERY, 39(2), 224–225.
MeSH headings : Animals; Cadaver; Cats / surgery; Dogs / surgery; Embalming / methods; Surgery, Veterinary / education; Surgery, Veterinary / methods
TL;DR:
A technique of cadaveric evisceration and freezing shortly after death is used to eliminate concerns about exposure of laboratory instructors and participants to formaldehyde.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
4. Quality Education
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
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