College of Veterinary Medicine - General

Works Published in 2020

search works

Displaying works 1 - 20 of 29 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2020 article

Performance Comparison of Massively Parallel Sequencing (MPS) Instruments Using Single-Nucleotide Polymorphism (SNP) Panels for Ancestry

SLAS TECHNOLOGY.

By: A. Cooley*, K. Meiklejohn n, N. Damaso*, J. Robertson* & T. Cruz*

author keywords: massively parallel DNA sequencing; automation; single-nucleotide polymorphisms (SNPs); ancestry; forensic DNA typing
MeSH headings : High-Throughput Nucleotide Sequencing; Polymorphism, Single Nucleotide; Workflow
TL;DR: The results indicated that automating the workflow with the Ion Chef system reduced the labor involved and increased the sequencing quality, and Ancestry predictions were concordant for the mock forensic-type samples sequenced on both massively parallel sequencing systems. (via Semantic Scholar)
UN Sustainable Development Goal Categories
8. Decent Work and Economic Growth (OpenAlex)
Source: ORCID
Added: December 16, 2022

2020 article

Comparison of unilateral rostral, middle and caudal segmental mandibulectomies as an alternative treatment for unilateral temporomandibular joint ankylosis in cats: an ex vivo study

JOURNAL OF FELINE MEDICINE AND SURGERY.

author keywords: Temporomandibular joint; TMJ; ankylosis; mandibulectomy
MeSH headings : Animals; Ankylosis / surgery; Ankylosis / veterinary; Cat Diseases; Cats; Mandible / surgery; Mandibular Osteotomy / veterinary; Temporomandibular Joint / surgery; Temporomandibular Joint Disorders / surgery; Temporomandibular Joint Disorders / veterinary
TL;DR: The caudal segmental mandibulectomy is a viable surgical alternative that may show a similar outcome to other surgical techniques and may eliminate the risk of iatrogenic periarticular neurovascular damage inherent to more invasive surgeries performed at the temporomandibular joint area. (via Semantic Scholar)
UN Sustainable Development Goal Categories
5. Gender Equality (Web of Science)
Source: ORCID
Added: April 20, 2021

2020 article

Emergent functions of cyclin-dependent kinase 4 regulating aurora b and cenpp transcription

Lee, S. H., Rodriguez, L. R., Marval, P. L. M., & Rodriguez-Puebla, M. L. (2020, August). CANCER RESEARCH, Vol. 80.

By: S. Lee n, L. Rodriguez*, P. Marval & M. Rodriguez-Puebla n

Source: Web Of Science
Added: March 8, 2021

2020 journal article

Evaluation of repeated dosing of a dexmedetomidine oromucosal gel for treatment of noise aversion in dogs over a series of noise events

VETERINARY RECORD, 187(12).

MeSH headings : Animals; Anti-Anxiety Agents / administration & dosage; Anti-Anxiety Agents / therapeutic use; Anxiety / drug therapy; Behavior, Animal / drug effects; Cost of Illness; Dexmedetomidine / administration & dosage; Dexmedetomidine / therapeutic use; Dogs / psychology; Fear / drug effects; Female; Gels; Humans; Male; Noise / adverse effects; Surveys and Questionnaires
TL;DR: Repeated use of dexmedetomidine gel for noise events resulted in decreased need for administration and overall burden of care was manageable, yet many owners agreed with statements regarding frustration, stress, guilt, guilt and sadness about their dog’s condition. (via Semantic Scholar)
Sources: Web Of Science, ORCID
Added: March 1, 2021

2020 article

Early radiation-induced oral pain signaling responses are reduced with pentoxifylline treatment

VETERINARY RADIOLOGY & ULTRASOUND.

By: M. Price n, Y. Lai n, K. Marcus n, J. Robertson n, B. Lascelles n & M. Nolan n

author keywords: glossitis; mucositis; TNF‐ α TRPV1; TRPV4
MeSH headings : Animals; Capsaicin / pharmacology; Histamine / pharmacology; Mice; Pain / prevention & control; Pain / veterinary; Pentoxifylline / therapeutic use; Pilot Projects; Prospective Studies; Radiation-Protective Agents / therapeutic use; Radiotherapy / adverse effects; Sensory System Agents / pharmacology; Signal Transduction / drug effects; Stomatitis / complications; Stomatitis / drug therapy; Stomatitis / etiology; Tumor Necrosis Factor-alpha / analysis; Tumor Necrosis Factor-alpha / metabolism
TL;DR: Although PTX treatment did not reduce glossitis severity or mitigate weight loss in mice with RIM/RAP, it did inhibit the upregulation of TNF-α's receptor that normally accompanies RIM, and it also reduced neuronal responsiveness to each of the aforementioned chemical stimuli. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: February 3, 2021

2020 journal article

Clostridioides difficile carriage in animals and the associated changes in the host fecal microbiota

ANAEROBE, 66.

By: R. Thanissery n, M. McLaren n, A. Rivera n, A. Reed n, N. Betrapally n, T. Burdette n, J. Winston n, M. Jacob n, B. Callahan n, C. Theriot n

author keywords: C. difficile; C. hiranonis; Microbiome; Ribotype; Antibiotic resistance; Animal; Canine; Equine; Feline
MeSH headings : Animals; Anti-Bacterial Agents / pharmacology; Bacterial Toxins / genetics; Bacterial Toxins / metabolism; Bacterial Typing Techniques; Cats; Chlorocebus aethiops; Clostridioides difficile / classification; Clostridioides difficile / drug effects; Clostridioides difficile / physiology; Clostridium Infections / epidemiology; Clostridium Infections / microbiology; Clostridium Infections / veterinary; Coculture Techniques; Dogs; Feces / microbiology; Female; Gastrointestinal Microbiome; Horses; Hospitals, Animal; Host-Pathogen Interactions; Male; Microbial Interactions; Microbial Sensitivity Tests; North Carolina; Polymerase Chain Reaction; Prevalence; RNA, Ribosomal, 16S; Ribotyping; Risk Factors; Tertiary Healthcare; Vero Cells
TL;DR: Experimental results showed a clear antagonistic relationship between the two strains in vitro, suggesting that commensal Clostridia might play a role in colonization resistance against C. difficile in different hosts. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: January 11, 2021

2020 journal article

Cardiac Stromal Cell Patch Integrated with Engineered Microvessels Improves Recovery from Myocardial Infarction in Rats and Pigs

ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(11), 6309–6320.

By: T. Su n, K. Huang n, K. Mathews n, V. Scharf n, S. Hu n, Z. Li n, B. Frame*, J. Cores n ...

author keywords: microfluidics; cardiac patch; cardiac stromal cells; myocardial infarction; porcine model
MeSH headings : Animals; Microvessels; Myocardial Infarction / therapy; Myocytes, Cardiac; Neovascularization, Physiologic; Rats; Stromal Cells; Swine
TL;DR: It is shown that BMV-CSC patch transplantation significantly promoted cardiac function, reduced scar size, increased viable myocardial tissue, promoted neovascularization, and suppressed inflammation in rat and porcine MI models, demonstrating enhanced therapeutic efficacy compared to conventional cardiac stromal cell patches. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: December 11, 2020

2020 journal article

Ligation of the Maxillary Artery Prior to Caudal Maxillectomy in the Dog-A Description of the Technique, Retrospective Evaluation of Blood Loss, and Cadaveric Evaluation of Maxillary Artery Anatomy

FRONTIERS IN VETERINARY SCIENCE, 7.

By: K. Carroll n & K. Mathews n

author keywords: caudal maxillectomy; preligation; hemorrhage; blood loss; maxillary artery ligation
TL;DR: Results demonstrate the effectiveness of preligation of the maxillary artery in preventing hemorrhage in caudal maxillectomies in dogs and this represents an improvement in outcome over previously reported studies. (via Semantic Scholar)
Source: Web Of Science
Added: December 11, 2020

2020 journal article

Development of Biomimetic Antimicrobial Platelet-Like Particles Comprised of Microgel Nanogold Composites

REGENERATIVE ENGINEERING AND TRANSLATIONAL MEDICINE, 6(3), 299–309.

By: E. Sproul n, S. Nandi n, E. Chee n, S. Sivadanam n, B. Igo n, L. Schreck*, A. Brown n

author keywords: Synthetic platelet; Fibrin; Hemostatic material; Trauma; Antimicrobial material; Microgels
TL;DR: These results demonstrate NGCs fabricated through noncovalent and covalent methods retain deformability necessary for clot collapse and exhibit some antimicrobial potential, and are promising materials for preventing blood loss and infection following traumatic injury. (via Semantic Scholar)
Source: Web Of Science
Added: October 12, 2020

2020 article

Gonioscopic iridocorneal angle morphology and incidence of postoperative ocular hypertension and glaucoma in dogs following cataract surgery

VETERINARY OPHTHALMOLOGY.

author keywords: canine; glaucoma; gonioscopy; iridocorneal angle; phacoemulsification; postoperative hypertension
MeSH headings : Age Factors; Animals; Cataract / complications; Cataract / pathology; Cataract / veterinary; Cornea / pathology; Dog Diseases / epidemiology; Dog Diseases / pathology; Dog Diseases / surgery; Dogs; Female; Glaucoma / epidemiology; Glaucoma / etiology; Glaucoma / pathology; Glaucoma / veterinary; Gonioscopy / veterinary; Incidence; Iris / pathology; Male; Ocular Hypertension / epidemiology; Ocular Hypertension / etiology; Ocular Hypertension / pathology; Ocular Hypertension / veterinary; Phacoemulsification / adverse effects; Phacoemulsification / veterinary; Postoperative Complications / epidemiology; Postoperative Complications / veterinary; Retrospective Studies; Risk Factors; Sex Factors
TL;DR: The ZibWest angle index may predict increased risk for developing medically unresponsive glaucoma with cataract surgery, and female sex, and increased patient age, surgical time, and surgeon experience were associated with increased postoperative morbidity. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: September 23, 2020

2020 journal article

Computed tomography in two recumbencies aides in the identification of pulmonary bullae in dogs with spontaneous pneumothorax

VETERINARY RADIOLOGY & ULTRASOUND, 61(6), 641–648.

author keywords: bleb; bullous emphysema; diagnosis
MeSH headings : Animals; Dogs; Female; Male; Dog Diseases / diagnostic imaging; Dog Diseases / physiopathology; Lung Diseases / complications; Lung Diseases / diagnostic imaging; Lung Diseases / veterinary; Observer Variation; Pneumothorax / complications; Pneumothorax / diagnostic imaging; Pneumothorax / veterinary; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Supine Position; Tomography, X-Ray Computed / veterinary
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: September 21, 2020

2020 journal article

The effect of spontaneous osteoarthritis on conditioned pain modulation in the canine model

SCIENTIFIC REPORTS, 10(1).

By: K. Chiu n, J. Hash n, R. Meyers n & B. Lascelles n

MeSH headings : Animals; Chronic Pain; Conditioning, Classical / physiology; Disease Models, Animal; Dogs; Humans; Osteoarthritis / physiopathology; Pain / physiopathology; Pain Management; Somatoform Disorders / physiopathology
TL;DR: These are the first data showing that EPM impairment is associated with canine OA pain, and the spontaneous OA dog model may be used to test drugs that normalize EPM function. (via Semantic Scholar)
Source: Web Of Science
Added: September 14, 2020

2020 journal article

Anthropogenic Contaminants and Histopathological Findings in Stranded Cetaceans in the Southeastern United States, 2012-2018

FRONTIERS IN MARINE SCIENCE, 7.

By: A. Page-Karjian*, C. Lo*, B. Ritchie*, C. Harms n, D. Rotstein*, S. Han*, S. Hassan*, A. Lehner* ...

author keywords: dolphins; endocrine disrupting contaminants; EDCs; heavy metals; mercury; odontocete; pathology; toxicity
TL;DR: Sublethal cellular changes related to toxicant exposure in free-ranging odontocetes may lead to health declines and, in combination with other factors, may contribute to stranding. (via Semantic Scholar)
UN Sustainable Development Goal Categories
14. Life Below Water (OpenAlex)
Source: Web Of Science
Added: August 24, 2020

2020 journal article

Platelet-like particles improve fibrin network properties in a hemophilic model of provisional matrix structural defects

JOURNAL OF COLLOID AND INTERFACE SCIENCE, 577, 406–418.

author keywords: Fibrin; Biomimetic; Platelet; Hemophilia; Biomaterials
MeSH headings : Blood Coagulation; Blood Platelets; Fibrin; Plasma; Wound Healing
TL;DR: PLPs improved clot network density, force generation, and stiffness, and promoted fibroblast migration within an in vitro model of early wound healing under hemophilic conditions, indicating that PLPs could provide a biomimetic platform for improving wound healing events in disease conditions that cause deficient fibrin network formation. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 24, 2020

2020 journal article

Mucosal Vaccination with UV-Inactivated Chlamydia suis in Pre-Exposed Outbred Pigs Decreases Pathogen Load and Induces CD4 T-Cell Maturation into IFN-γ+ Effector Memory Cells

Vaccines, 8(3), 353.

By: A. Amaral n, K. Rahman*, A. Kick n, L. Cortes n, J. Robertson n, B. Kaltenboeck*, V. Gerdts*, C. O’Connell* ...

author keywords: chlamydia trachomatis; chlamydia suis; large animal model; swine; translational research; vaccine development; TriAdj; vaccination; immunology; T cells; effector memory
TL;DR: Results indicate that Cs vaccination of pre-exposed pigs effectively boosts a non-protective immune response induced by natural infection; moreover, they suggest that a similar approach could be applied to human vaccine trials. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: ORCID
Added: July 23, 2020

2020 journal article

A mutation in MTM1 causes X-Linked myotubular myopathy in Boykin spaniels

NEUROMUSCULAR DISORDERS, 30(5), 353–359.

author keywords: Canine; Centronuclear myopathy; Myotubularin myopathy
MeSH headings : Animals; Dogs; Male; Myopathies, Structural, Congenital / genetics; Myopathies, Structural, Congenital / pathology; Myopathies, Structural, Congenital / physiopathology; Pedigree; Phenotype; Protein Tyrosine Phosphatases, Non-Receptor / genetics
TL;DR: The purpose of this study was to report the findings of clinical and genetic evaluation of a 3-month old male Boykin spaniel that presented with progressive weakness that causes a severe form of X-linked myotubular myopathy, comparable to the human counterpart. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Sources: Web Of Science, ORCID
Added: June 29, 2020

2020 journal article

Ursodeoxycholic Acid (UDCA) Mitigates the Host Inflammatory Response during Clostridioides difficile Infection by Altering Gut Bile Acids

INFECTION AND IMMUNITY, 88(6).

author keywords: C. difficile; FXR; UDCA; bile acids; inflammation; microbiome; ursodiol
MeSH headings : Animals; Bile Acids and Salts / metabolism; Biomarkers; Clostridioides difficile / drug effects; Clostridium Infections / drug therapy; Clostridium Infections / genetics; Clostridium Infections / metabolism; Clostridium Infections / microbiology; Computational Biology / methods; Dose-Response Relationship, Drug; Fibroblast Growth Factors / metabolism; Fragile X Mental Retardation Protein / metabolism; Gastrointestinal Microbiome / drug effects; Gene Expression Profiling; Host-Pathogen Interactions / drug effects; Host-Pathogen Interactions / genetics; Humans; Life Cycle Stages; Mice; Signal Transduction; Transcriptome; Ursodeoxycholic Acid / pharmacology; Ursodeoxycholic Acid / physiology
TL;DR: Although ursodiol pretreatment did not result in a consistent decrease in the C. difficile life cycle in vivo, it was able to attenuate an overly robust inflammatory response that is detrimental to the host during CDI. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: June 15, 2020

2020 article

Neonatal Fibrin Scaffolds Promote Enhanced Cell Adhesion, Migration, and Wound Healing In Vivo Compared to Adult Fibrin Scaffolds

CELLULAR AND MOLECULAR BIOENGINEERING.

By: K. Nellenbach n, S. Nandi n, C. Peeler n, A. Kyu n & A. Brown n

TL;DR: In vivo significantly smaller wound areas and greater epidermal thickness were observed when wounds were treated with neonatal fibrin compared to adultfibrin or a saline control, indicating that fibr in scaffolds sourced from neonatal plasma could improve healing outcomes compared to scaffoldsourced from adult plasma. (via Semantic Scholar)
Source: Web Of Science
Added: June 15, 2020

2020 journal article

Association of fecal sample collection technique and treatment history with Tritrichomonas foetus polymerase chain reaction test results in 1717 cats

Journal of Veterinary Internal Medicine.

James Robertson

author keywords: diarrhea; retrospective; risk factors; ronidazole
MeSH headings : Animals; Antiprotozoal Agents / therapeutic use; Cat Diseases / diagnosis; Cat Diseases / drug therapy; Cat Diseases / parasitology; Cats; Feces / parasitology; Female; Male; Polymerase Chain Reaction / veterinary; Protozoan Infections, Animal / diagnosis; Protozoan Infections, Animal / drug therapy; Protozoan Infections, Animal / parasitology; Retrospective Studies; Ronidazole / therapeutic use; Specimen Handling / veterinary; Tritrichomonas foetus / isolation & purification; United States
TL;DR: Results of this study support that fecal samples collected by loop might be better for PCR diagnosis of T. foetus infection and Lack of association of ronidazole with PCR test results and a 21% all‐potential‐causes failure rate of rONidazoles in cats with preconfirmed infection are important limitations to use of this drug. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
5. Gender Equality (Web of Science)
Source: ORCID
Added: June 12, 2020

2020 journal article

Ultrasound Enhanced Synthetic Platelet Therapy for Augmented Wound Repair

ACS BIOMATERIALS SCIENCE & ENGINEERING, 6(5), 3026–3036.

author keywords: biomimetic; fibrin; wound healing clot retraction; artificial platelet
MeSH headings : Blood Coagulation; Blood Platelets; Clot Retraction; Fibrin; Wound Healing
TL;DR: Application of ultrasound in combination with a subtherapeutic dosage of PLPs resulted in increased clot density and stiffness, improved fibroblast migration in vitro and increased epidermal thickness and angiogenesis in vivo, indicating that this combination therapy has potential to facilitate multiphase pro-healing outcomes. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: June 8, 2020

Citation Index includes data from a number of different sources. If you have questions about the sources of data in the Citation Index or need a set of data which is free to re-distribute, please contact us.

Certain data included herein are derived from the Web of Science© and InCites© (2024) of Clarivate Analytics. All rights reserved. You may not copy or re-distribute this material in whole or in part without the prior written consent of Clarivate Analytics.