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Works Published in 1999

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1999 journal article

RNase P RNAs from some Archaea are catalytically active

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 96(14), 7803–7808.

By: J. Pannucci n, E. Haas n, T. Hall n, J. Harris n & J. Brown n

MeSH headings : Archaea / enzymology; Archaea / genetics; Bacillus / enzymology; Bacillus / genetics; Base Sequence; Conserved Sequence; Endoribonucleases / chemistry; Endoribonucleases / genetics; Endoribonucleases / metabolism; Kinetics; Methanobacterium / enzymology; Methanobacterium / genetics; Models, Molecular; Molecular Sequence Data; Nucleic Acid Conformation; Phylogeny; RNA, Archaeal / chemistry; RNA, Archaeal / genetics; RNA, Archaeal / metabolism; RNA, Bacterial / metabolism; RNA, Catalytic / chemistry; RNA, Catalytic / genetics; RNA, Catalytic / metabolism; Ribonuclease P
TL;DR: The properties of the archaeal RNase P RNAs (high ionic-strength requirement, low affinity for substrate, and catalytic reconstitution by bacterialRNase P protein) are similar to synthetic RNases that contain all of the catalytic core of the bacterial RNA but lack phylogenetically variable, stabilizing elements. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

1999 journal article

The Ribonuclease P Database

NUCLEIC ACIDS RESEARCH, 27(1), 314–314.

By: J. Brown n

MeSH headings : Databases, Factual; Endoribonucleases / chemistry; Endoribonucleases / genetics; Endoribonucleases / metabolism; Eukaryotic Cells / chemistry; Eukaryotic Cells / metabolism; Information Storage and Retrieval; Internet; Models, Molecular; Nucleic Acid Conformation; Organelles / chemistry; Organelles / genetics; Organelles / metabolism; Phylogeny; Protein Structure, Secondary; RNA, Archaeal / chemistry; RNA, Archaeal / genetics; RNA, Archaeal / metabolism; RNA, Bacterial / chemistry; RNA, Bacterial / genetics; RNA, Bacterial / metabolism; RNA, Catalytic / chemistry; RNA, Catalytic / genetics; RNA, Catalytic / metabolism; Ribonuclease P; Ribonucleoproteins / chemistry; Ribonucleoproteins / genetics; Ribonucleoproteins / metabolism; Sequence Alignment; Software
TL;DR: Ribonuclease P is responsible for the 5'-maturation of tRNA precursors, and in bacteria the RNA subunit alone is catalytically active in vitro, i.e., it is a ribozyme. (via Semantic Scholar)
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Source: Web Of Science
Added: August 6, 2018

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