Works Published in 2007

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Displaying works 21 - 40 of 76 in total

Sorted by most recent date added to the index first, which may not be the same as publication date order.

2007 journal article

The role of epistasis in the manifestation of heterosis: A systems-oriented approach

GENETICS, 177(3), 1815–1825.

By: A. Melchinger*, H. Utz*, H. Piepho, Z. Zeng n & C. Schoen

MeSH headings : Animals; Breeding; Chromosome Mapping; Epistasis, Genetic; Genes, Dominant; Genetic Markers; Hybrid Vigor; Mathematics; Models, Genetic; Quantitative Trait Loci; Systems Biology
TL;DR: A new type of heterotic effect is defined denoted as augmented dominance effect di* that comprises the dominance effect at each QTL minus half the sum of additive × additive interactions with all other QTL. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Simultaneous clustering of gene expression data with clinical chemistry and pathological evaluations reveals phenotypic prototypes

BMC SYSTEMS BIOLOGY, 1.

By: P. Bushel*, R. Wolfinger* & G. Gibson n

MeSH headings : Acetaminophen / toxicity; Algorithms; Animals; Clinical Chemistry Tests / statistics & numerical data; Cluster Analysis; Data Interpretation, Statistical; Disease Models, Animal; Gene Expression Profiling / statistics & numerical data; Heart Diseases / blood; Heart Diseases / genetics; Heart Diseases / pathology; Humans; Liver / drug effects; Liver / pathology; Necrosis; Phenotype; Rats
TL;DR: Following modk-prototypes clustering of the acetaminophen-exposed samples, informative genes from the cluster prototypes were identified that are descriptive of, and phenotypically anchored to, levels of necrosis of the centrilobular region of the rat liver. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Impact of population structure on genetic diversity of a potential vaccine target in the canine hookworm (Ancylostoma caninum)

JOURNAL OF PARASITOLOGY, 93(4), 796–805.

By: J. Moser n, I. Carbone n, P. Arasu n & G. Gibson n

MeSH headings : Ancylostoma / genetics; Ancylostoma / growth & development; Ancylostoma / immunology; Ancylostomiasis / parasitology; Ancylostomiasis / veterinary; Animals; DNA, Helminth / chemistry; Dog Diseases / parasitology; Dogs; Electron Transport Complex IV / genetics; Electron Transport Complex IV / immunology; Female; Genetic Variation; Haplotypes; Helminth Proteins / genetics; Helminth Proteins / immunology; Male; Maryland; North Carolina; Population Dynamics; Queensland; Vaccines / genetics; Vaccines / immunology
TL;DR: Test whether positive selection, population structure, or both affect genetic variation at the candidate vaccine target Ancylostoma secreted protein 1 (asp-1), using the statistical population analysis tools found in the SNAP Workbench. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Association of polymorphisms in odorant-binding protein genes with variation in olfactory response to benzaldehyde in Drosophila

GENETICS, 177(3), 1655–1665.

MeSH headings : Animals; Benzaldehydes; Drosophila Proteins / genetics; Drosophila melanogaster / genetics; Drosophila melanogaster / physiology; Female; Genes, Insect; Genetics, Population; Male; Models, Molecular; Molecular Sequence Data; Multigene Family; Nucleic Acid Conformation; Odorants; Phenotype; Polymorphism, Genetic; Polymorphism, Single Nucleotide; RNA Precursors / chemistry; RNA Precursors / genetics; Receptors, Odorant / genetics
TL;DR: Model predictions of alternative pre-mRNA secondary structures associated with polymorphic sites suggest that alterations in Obp mRNA structure could contribute to phenotypic variation in olfactory behavior. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

A semiparametric approach for composite functional mapping of dynamic quantitative traits

GENETICS, 177(3), 1859–1870.

MeSH headings : Algorithms; Chromosome Mapping / methods; Chromosome Mapping / statistics & numerical data; Likelihood Functions; Models, Genetic; Models, Statistical; Monte Carlo Method; Oryza / genetics; Oryza / growth & development; Polymorphism, Restriction Fragment Length; Quantitative Trait Loci; Regression Analysis
TL;DR: A statistical framework for mapping QTL that affect dynamic traits by capitalizing on the strengths of functional mapping and composite interval mapping is presented, leading to the identification of multiple QTL, some of which are linked on the same chromosome, that control the developmental trajectory of leaf age. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 review

The genomics of lactic acid bacteria

[Review of ]. TRENDS IN MICROBIOLOGY, 15(12), 546–553.

MeSH headings : Dairy Products / microbiology; Genome, Bacterial; Gram-Positive Bacteria / classification; Gram-Positive Bacteria / genetics; Gram-Positive Bacteria / metabolism; Humans; Lactic Acid / biosynthesis; Lactic Acid / metabolism; Probiotics
TL;DR: A review of the genome sequencing of 20 lactic acid bacteria provides an expanded view of their genetic and metabolic capacities and enables researchers to perform functional and comparative genomic studies. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

The extent of linkage disequilibrium in rice (Oryza sativa L.)

GENETICS, 177(4), 2223–2232.

By: K. Mather n, A. Caicedo n, N. Polato*, K. Olsen n, S. McCouch* & M. Purugganan n

MeSH headings : Base Sequence; Crops, Agricultural / genetics; Genetic Linkage; Genome, Plant; Linkage Disequilibrium; Molecular Sequence Data; Oryza / genetics; Polymorphism, Single Nucleotide; Recombination, Genetic
TL;DR: The feasibility of genomewide association mapping in cultivated Asian rice using a modest number of SNPs is demonstrated and variation in LD patterns among genomic regions is suggested. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Structural polymorphism and diversifying selection on the pregnancy malaria vaccine candidate VAR2CSA

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 155(2), 103–112.

By: J. Bockhorst*, F. Lu*, J. Janes*, J. Keebler n, B. Gamain*, P. Awadalla n, X. Su*, R. Samudrala*, N. Jojica, J. Smith*

author keywords: antigenic variation; malaria; Plasmodium falciparum; var genes
MeSH headings : Animals; Antigens, Protozoan / chemistry; Antigens, Protozoan / genetics; Antigens, Protozoan / immunology; Computational Biology / methods; DNA, Protozoan / chemistry; DNA, Protozoan / genetics; Female; Geography; Humans; Malaria / immunology; Malaria / parasitology; Malaria Vaccines / immunology; Models, Molecular; Molecular Sequence Data; Phylogeny; Plasmodium falciparum / genetics; Plasmodium falciparum / isolation & purification; Polymorphism, Genetic; Pregnancy; Pregnancy Complications, Parasitic / immunology; Pregnancy Complications, Parasitic / prevention & control; Protein Structure, Tertiary; Selection, Genetic; Sequence Analysis, DNA; Sequence Homology, Amino Acid
TL;DR: A novel phylogenetic approach is developed that incorporates recombination and tracks new mutations in segment types in the VAR2CSA Duffy binding-like (DBL) adhesion domains and validate a new approach to modeling protein evolution in the presence of frequent recombination. (via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being (Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Speed-mapping quantitative trait loci using microarrays

NATURE METHODS, 4(10), 839–841.

MeSH headings : Animals; Drosophila melanogaster / genetics; Drosophila melanogaster / growth & development; Female; Gene Expression Profiling / methods; Longevity / genetics; Male; Oligonucleotide Array Sequence Analysis / methods; Polymorphism, Genetic / genetics; Quantitative Trait Loci
TL;DR: A rapid, economical method for high-resolution quantitative trait locus (QTL) mapping using microarrays for selective genotyping of pooled DNA samples is developed. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Silencing of the aflatoxin gene cluster in a diploid strain of Aspergillus flavus is suppressed by ectopic aflR expression

GENETICS, 176(4), 2077–2086.

By: C. Smith*, C. Woloshuk*, D. Robertson & G. Payne n

MeSH headings : Aflatoxins / genetics; Aspergillus flavus / genetics; Base Sequence; DNA Primers / genetics; DNA, Fungal / genetics; DNA-Binding Proteins / genetics; Diploidy; Fungal Proteins / genetics; Gene Dosage; Gene Expression; Gene Silencing; Genes, Fungal; Multigene Family; Mutation; Sequence Deletion; Transcription Factors / genetics; Transformation, Genetic
TL;DR: Gene expression analysis revealed a form of reversible silencing based on the position of aflR is likely preventing the aflatoxin genes from being expressed in 649 × wild-type diploids, specific to the a flatoxin gene cluster. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 patent

Putrescine-n-methyltransferase promoter

Washington, DC: U.S. Patent and Trademark Office.

By: M. Conkling & Y. Li

Source: NC State University Libraries
Added: August 6, 2018

2007 patent

Plant promoter sequence

Washington, DC: U.S. Patent and Trademark Office.

By: M. Conkling & Y. Li

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

Expression profiling on soybean leaves reveals integration of ER- and osmotic-stress pathways

BMC GENOMICS, 8.

By: A. Irsigler*, M. Costa*, P. Zhang n, P. Reis*, R. Dewey n, R. Boston n, E. Fontes*

MeSH headings : DNA, Complementary / genetics; Endoplasmic Reticulum / metabolism; Gene Expression Profiling / methods; Oligonucleotide Array Sequence Analysis; Osmosis; Plant Leaves / genetics; Plant Leaves / metabolism; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction / genetics; Signal Transduction / physiology; Soybeans / genetics; Soybeans / metabolism
TL;DR: This scenario indicates that polyethylene glycol (PEG)-induced cellular dehydration and ER stress elicited very different up-regulated responses within a 10-h stress treatment regime, and provides a list of candidate regulatory components, which may integrate the osmotic-stress and ER-stress signaling pathways in plants. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 patent

AbiZ phage resistance gene

Washington, DC: U.S. Patent and Trademark Office.

Source: NC State University Libraries
Added: August 6, 2018

2007 journal article

A WD40 domain cyclophilin interacts with histone H3 and functions in gene repression and organogenesis in Arabidopsis

PLANT CELL, 19(8), 2403–2416.

MeSH headings : Arabidopsis / embryology; Arabidopsis / genetics; Arabidopsis Proteins / chemistry; Arabidopsis Proteins / genetics; Arabidopsis Proteins / metabolism; Body Patterning; Cell Nucleus / metabolism; Cyclophilins / chemistry; Cyclophilins / genetics; Cyclophilins / metabolism; Flowers / anatomy & histology; Gene Expression Regulation, Plant; Genes, Homeobox; Histones / metabolism; Meristem / metabolism; Methylation; Mutant Proteins / isolation & purification; Mutation / genetics; Organogenesis; Plant Leaves / embryology; Plant Leaves / genetics; Plant Roots / growth & development; Protein Binding; Protein Structure, Tertiary; Protein Transport; Repressor Proteins / metabolism
TL;DR: A WD40 domain cyclophilin, CYCLOPHILIN71 (CYP71), is identified, which functions in gene repression and organogenesis in Arabidopsis thaliana and it is proposed that it serves as a highly conserved histone remodeling factor involved in chromatin-based gene silencing in eukaryotic organisms. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
Sources: Web Of Science, ORCID
Added: August 6, 2018

2007 journal article

The negative influence of N-mediated TMV resistance on yield in tobacco: linkage drag versus pleiotropy

THEORETICAL AND APPLIED GENETICS, 115(2), 169–178.

By: R. Lewis n, L. Linger*, M. Wolff* & E. Wernsman n

MeSH headings : Cloning, Molecular; Genetic Linkage; Immunity, Innate / genetics; Inbreeding; Mutagenesis, Insertional; Plant Diseases / genetics; Plant Diseases / virology; Plant Proteins / genetics; Plant Proteins / physiology; Plants, Genetically Modified / physiology; Plants, Genetically Modified / virology; Tobacco / genetics; Tobacco / physiology; Tobacco / virology; Tobacco Mosaic Virus / physiology; Transformation, Genetic; Transgenes
TL;DR: Comparisons of the 14 corresponding transgenic NN backcross-derived lines with K326 indicated that linkage drag is the main factor contributing to reduced yields in TMV-resistant flue-cured tobacco germplasm. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
3. Good Health and Well-being (OpenAlex)
13. Climate Action (Web of Science)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

The appendage role of insect disco genes and possible implications on the evolution of the maggot larval form

DEVELOPMENTAL BIOLOGY, 309(1), 56–69.

author keywords: drosophila; segment identity; zinc finger; appendage; limb; pattern formation
MeSH headings : Animals; Biological Evolution; Body Patterning; DNA-Binding Proteins / metabolism; Drosophila / embryology; Drosophila / growth & development; Drosophila / metabolism; Drosophila Proteins / metabolism; Head / embryology; Head / growth & development; Larva / growth & development; Larva / metabolism; Transcription Factors / metabolism; Tribolium / embryology; Tribolium / growth & development; Tribolium / metabolism
TL;DR: It is proposed that the disco genes always function as appendage factors, but their appendage nature is masked during Drosophila embryogenesis due to the reduction of limb fields in the maggot style Drosophile larva. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Synchronization and superovulation of mature cycling gilts for the collection of pronuclear stage embryos

ANIMAL REPRODUCTION SCIENCE, 100(3-4), 402–410.

By: J. Sommer n, E. Collins n, J. Estrada n & R. Petters n

author keywords: gilt; superovulation; estrous synchronization; pronuclear stage embryo; PG600 (R); prostaglandin F-2 alpha; transgenic
MeSH headings : Animals; Chorionic Gonadotropin / pharmacology; Dinoprost / analogs & derivatives; Dinoprost / pharmacology; Embryo, Mammalian; Estrous Cycle; Estrus Synchronization / methods; Female; Superovulation / drug effects; Superovulation / physiology; Swine / physiology
TL;DR: An efficient protocol to synchronize and superovulate mature pigs for the collection of pronuclear stage embryos suitable for DNA microinjection and Pigs 10-16 days after the beginning of standing estrus have been successfully synchronized into estrus using this protocol. (via Semantic Scholar)
Source: Web Of Science
Added: August 6, 2018

2007 journal article

Swine generated by somatic cell nuclear transfer have increased incidence of intrauterine growth restriction (IUGR)

CLONING AND STEM CELLS, 9(2), 229–236.

By: J. Estrada n, J. Sommer n, B. Collins n, B. Mir n, A. Martin n, A. York n, R. Petters n, J. Piedrahita n

MeSH headings : Animals; Birth Weight / physiology; Fetal Growth Retardation; Insemination, Artificial; Litter Size / physiology; Nuclear Transfer Techniques; Swine
TL;DR: SCNT-derived pigs are excellent models to study epigenetic factors and genes involved in IUGRs, and to develop effective means to improve fetal growth in humans and animals, and there are some differences between SCNT- derived and AI litters. (via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018

2007 journal article

QTL mapping with near-isogenic lines in maize

THEORETICAL AND APPLIED GENETICS, 114(7), 1211–1228.

By: S. Szalma n, B. Hostert*, J. LeDeaux*, C. Stuber n & J. Holland n

MeSH headings : Alleles; Chromosome Mapping; Chromosomes, Plant; Crosses, Genetic; Genes, Plant; Genetic Markers; Genotype; Models, Genetic; Phenotype; Polymorphism, Restriction Fragment Length; Quantitative Trait Loci; Time Factors; Zea mays / genetics
TL;DR: QTLs affecting days to anthesis, days to silking, and anthesis-silk interval were detected in both inbreds and hybrids in both environments, and different sets of QTLs were detected across environments, demonstrating the genetic complexity of flowering time. (via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger (Web of Science)
13. Climate Action (Web of Science)
15. Life on Land (Web of Science)
Source: Web Of Science
Added: August 6, 2018

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