Works Published in 2009
Displaying works 21 - 40 of 78 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2009 article
Animal models of autism spectrum disorders: Information for neurotoxicologists
Halladay, A. K., Amaral, D., Aschner, M., Bolivar, V. J., Bowman, A., DiCicco-Bloom, E., … Threadgill, D. W. (2009, September). NEUROTOXICOLOGY, Vol. 30, pp. 811–821.
author keywords: Animal models; Autism; Neurotoxicology; Symposium
MeSH headings : Animals; Child; Child Development Disorders, Pervasive / chemically induced; Child Development Disorders, Pervasive / genetics; Child Development Disorders, Pervasive / physiopathology; Child, Preschool; Disease Models, Animal; Drosophila melanogaster; Environment; Genetic Predisposition to Disease; Humans; Mice; Neurotoxicity Syndromes / complications; Toxicology
TL;DR:
The aim of the symposium was to provide researchers with up-to-date information on both the genetics of autism and how they are used in differing in vivo and in vitro animal models as well as to provide a background on the environmental exposures being tested on several animal models.
(via Semantic Scholar)
europepmc.org (repository)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 patent
Regulation of quinolate phosphoribosyl transferase expression
Source: NC State University Libraries
Added: August 6, 2018
2009 patent
Nucleic acid sequences encoding two-component sensing and regulatory proteins, antimicrobial proteins and uses therefor
Source: NC State University Libraries
Added: August 6, 2018
2009 patent
Lactobacillus acidophilus nucleic acid sequences encoding stress-related proteins and uses therefor
Source: NC State University Libraries
Added: August 6, 2018
2009 patent
Lactobacillus acidophillus nucleic acid sequences encoding cell surface protein homologues and uses therefore
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Elucidation of the transcription network governing mammalian sex determination by exploiting strain-specific susceptibility to sex reversal
GENES & DEVELOPMENT, 23(21), 2521–2536.
author keywords: Sex determination; genetical genomics; systems genetics; eQTL; transcription networks; organogenesis
MeSH headings : Animals; Breeding; Cluster Analysis; Disorders of Sex Development; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Genetic Variation; Gonads / metabolism; Male; Mice; Mice, Inbred C57BL; Quantitative Trait Loci / genetics; SOX9 Transcription Factor / metabolism; Sex Determination Processes; X Chromosome / genetics; Y Chromosome / genetics
TL;DR:
The results reveal the complex transcription architecture underlying sex determination, and provide a mechanism by which individuals may be sensitized for sex reversal, and estimated the F2 coexpression network and predicted roles for genes of unknown function based on their connectivity and position within the network.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 patent
Compositions comprising promoter sequences and methods of use
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Alcohol Sensitivity in Drosophila: Translational Potential of Systems Genetics
GENETICS, 183(2), 733–745.
MeSH headings : Alcohol Drinking / genetics; Animals; Cluster Analysis; Drosophila Proteins / genetics; Drosophila Proteins / metabolism; Drosophila melanogaster / genetics; Ethanol / pharmacology; Female; Gene Expression Regulation / drug effects; Gene Regulatory Networks; Genes, Insect / genetics; Genetic Variation; Genome, Insect / genetics; Genome-Wide Association Study / methods; Genotype; Humans; Inbreeding; Malate Dehydrogenase / genetics; Malate Dehydrogenase / metabolism; Male; Phenotype; Polymorphism, Single Nucleotide; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction
TL;DR:
Seven intronic single nucleotide polymorphisms of the Malic Enzyme 1 (ME1) gene that are associated with cocktail drinking in 1687 individuals of the Framingham Offspring cohort are identified, implicating that variation in levels of cytoplasmic malic enzyme may contribute to variation in alcohol consumption.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2009 review
A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB
[Review of ]. Human Molecular Genetics, 18(23), 4650–4661.
Source: NC State University Libraries
Added: August 6, 2018
2009 article
The Genomes of Root-Knot Nematodes
ANNUAL REVIEW OF PHYTOPATHOLOGY, Vol. 47, pp. 333–351.
author keywords: asexual reproduction; genetics; horizontal gene transfer; Meloidogyne; plant parasite
MeSH headings : Animals; Biological Evolution; Gene Transfer, Horizontal; Genome, Helminth; Nematoda / genetics; Plant Diseases / genetics; Plant Roots / genetics
TL;DR:
Sequencing revealed that Meloidogyne hapla, a diploid that reproduces by facultative, meiotic parthenogenesis, encodes approximately 14,200 genes in a compact, 54 Mpb genome, which is the smallest metazoan genome completed to date and suggests new routes to their control.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Role of autoinducer-2 on the adhesion ability of Lactobacillus acidophilus
JOURNAL OF APPLIED MICROBIOLOGY, 107(1), 269–279.
author keywords: autoinducer-2; Caco-2; microarray; probiotic
MeSH headings : Bacterial Adhesion / genetics; Bacterial Proteins / genetics; Caco-2 Cells / microbiology; Carbon-Sulfur Lyases / genetics; DNA, Bacterial / genetics; Gene Expression Regulation, Bacterial; Homoserine / analogs & derivatives; Homoserine / genetics; Homoserine / metabolism; Humans; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / metabolism; Lactones / metabolism; Microarray Analysis; Mutation; Phylogeny; Quorum Sensing / genetics; RNA, Bacterial / genetics
TL;DR:
Investigating whether or not the quorum‐sensing signalling molecule, autoinducer (AI)‐2, was produced by Lactobacillus acidophilus and affected adherence to intestinal epithelial cells found it likely promotes retention in the gastrointestinal tract and communication with the immune system.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Probiotics to minimize the disruption of faecal microbiota in healthy subjects undergoing antibiotic therapy
JOURNAL OF MEDICAL MICROBIOLOGY, 58(5), 663–670.
MeSH headings : Amoxicillin / therapeutic use; Anti-Bacterial Agents / pharmacology; Bacteroides / drug effects; Bacteroides / genetics; Bifidobacterium / drug effects; Bifidobacterium / genetics; Clavulanic Acid / therapeutic use; Clostridium / drug effects; Clostridium / genetics; Conserved Sequence; DNA Primers; DNA, Bacterial / genetics; Enterobacteriaceae / drug effects; Enterobacteriaceae / genetics; Eubacterium / drug effects; Eubacterium / genetics; Feces / microbiology; Humans; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Probiotics / therapeutic use
TL;DR:
This study indicates this mixture of probiotics promotes a more rapid return to pre-antibiotic baseline faecal bacterial microbiota.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
On the Fiedler vectors of graphs that arise from trees by Schur complementation of the Laplacian
LINEAR ALGEBRA AND ITS APPLICATIONS, 431(10), 1869–1880.
author keywords: Trees; Graph Laplacians; Fiedler vectors; Perron components
TL;DR:
This paper considers a point of articulation r in the graph G and derives a related graph G whose Laplacian matrix is L and shows how Fiedler vectors of G relate to the structure of G and provides bounds for the algebraic connectivity of G{r} in terms of the connected components at r in G.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 article
NCSU's Virtual Computing Lab: A Cloud Computing Solution
Schaffer, H. E., Averitt, S. F., Hoit, M. I., Peeler, A., Sills, E. D., & Vouk, M. A. (2009, July). COMPUTER, Vol. 42, pp. 94–97.
TL;DR:
The delivery of many diverse computing services over the Internet, with flexible provisioning, has led to much greater efficiency, substantial cost savings, and many ways to enable and empower end users.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
9. Industry, Innovation and Infrastructure
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Functional and geographical differentiation of candidate balanced polymorphisms in Arabidopsis thaliana
MOLECULAR ECOLOGY, 18(13), 2844–2855.
author keywords: adaptation; balancing selection; population genetics
MeSH headings : Alleles; Arabidopsis / genetics; Arabidopsis Proteins / genetics; DNA, Plant / genetics; Gene Expression Regulation, Plant; Genes, Plant; Genetics, Population; Genome, Plant; Polymorphism, Genetic; Selection, Genetic
TL;DR:
The data support a hypothesis of balancing selection at all three candidate loci and provide a basis for more detailed functional work by identifying possible functional differences that might be selectively maintained.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Web Of Science, NC State University Libraries
Added: August 6, 2018
2009 journal article
Estimates of natural selection due to protein tertiary structure inform the ancestry of biallelic loci
Gene, 441(1-2), 45–52.
MeSH headings : Evolution, Molecular; Gene Frequency; Humans; Polymorphism, Single Nucleotide; Protein Structure, Tertiary; Proteins / genetics; Selection, Genetic
TL;DR:
This work focuses on 140 nonsynonymous single nucleotide polymorphisms of humans that are in proteins with known tertiary structures and finds that the technique for employing protein tertiary structure information yields some biologically plausible results but that it does not substantially improve the inference of ancestral human allele types.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: NC State University Libraries
Added: August 6, 2018
2009 journal article
Energy stores are not altered by long-term partial sleep deprivation in Drosophila melanogaster
PLoS One, 4(7).
Source: NC State University Libraries
Added: August 6, 2018
2009 article
The Third International Conference of Quantitative Genetics
Weir, B. S., Hill, W. G., Zhu, J., & Zeng, Z.-B. (2009, June). GENETICA, Vol. 136, pp. 211–212.
MeSH headings : Animals; China; Genetics; Humans; Internationality
TL;DR:
The wide range of topics and methods discussed in these papers show the diversity of applications of quantitative genetics and of the technologies employed, and were run as a single session in order to foster interactions and exchange of ideas and problems among those working on these different systems, species and technologies.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Reconstructing ancestral ranges in historical biogeography: properties and prospects
JOURNAL OF SYSTEMATICS AND EVOLUTION, 47(5), 369–382.
author keywords: allopatry; ancestral range; ancestral state reconstruction; biogeography; dispersal; historical biogeography; review; speciation; statistics; vicariance
TL;DR:
It is explored how the form of allowed ancestral ranges and allowed transitions can both affect the outcome of ancestral range estimation and some promising avenues for future work in the development of model‐based approaches to biogeographic analysis are mentioned.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2009 journal article
Population-Based Discovery of Toxicogenomics Biomarkers for Hepatotoxicity Using a Laboratory Strain Diversity Panel
TOXICOLOGICAL SCIENCES, 110(1), 235–243.
author keywords: biomarkers; toxicogenomics; acetaminophen; microarray; liver; phenotypic anchoring
MeSH headings : Acetaminophen / toxicity; Analgesics, Non-Narcotic / toxicity; Animals; Biomarkers / analysis; Cell Death / genetics; Cell Proliferation / drug effects; Chemical and Drug Induced Liver Injury / genetics; Chemical and Drug Induced Liver Injury / pathology; Gene Expression / drug effects; Humans; Liver / pathology; Male; Mice; Oligonucleotide Array Sequence Analysis; Polymorphism, Single Nucleotide / drug effects; Population; Principal Component Analysis; RNA / biosynthesis; RNA / isolation & purification; Species Specificity; Toxicogenetics / standards; Transcription, Genetic / drug effects
TL;DR:
The data demonstrate that a multistrain approach may provide utility for understanding genotype-independent toxicity responses and facilitate identification of novel targets of therapeutic intervention.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
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