Works Published in 2010
Displaying works 21 - 40 of 46 in total
Sorted by most recent date added to the index first, which may not be the same as publication date order.
2010 journal article
Genomic Hotspots for Adaptation: The Population Genetics of Müllerian Mimicry in Heliconius erato
PLoS Genetics, 6(2), e1000796.
Ed(s): M. Nachman
MeSH headings : Adaptation, Physiological / genetics; Animals; Butterflies / genetics; Chromosomes, Artificial, Bacterial / genetics; Gene Expression Regulation; Genetic Loci / genetics; Genetic Variation; Genetics, Population; Genome / genetics; Genotype; Hybridization, Genetic; Linkage Disequilibrium / genetics; Open Reading Frames / genetics; Peru; Phenotype; Physical Chromosome Mapping; Pigmentation / genetics; Polymorphism, Single Nucleotide / genetics; Sequence Analysis, DNA
TL;DR:
Detailed characterize nucleotide variation, genotype-by-phenotype associations, linkage disequilibrium (LD), and candidate gene expression patterns across two unlinked genomic intervals that control yellow and red wing pattern variation among mimetic forms of Heliconius erato and provides convincing evidence for parallel changes in gene regulation across co-mimetic lineages.
(via Semantic Scholar)
doi.org (publisher)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Sources: Crossref, NC State University Libraries, NC State University Libraries
Added: August 6, 2018
2010 journal article
Current Progress on Statistical Methods for Mapping Quantitative Trait Loci from Inbred Line Crosses
JOURNAL OF BIOPHARMACEUTICAL STATISTICS, 20(2), 454–481.
author keywords: Inbred lines; Quantitative trait loci; Statistical methods
MeSH headings : Algorithms; Animals; Animals, Inbred Strains; Bayes Theorem; Crosses, Genetic; Data Interpretation, Statistical; Genome-Wide Association Study / statistics & numerical data; Genotype; Likelihood Functions; Models, Statistical; Phenotype; Quantitative Trait Loci; Reproducibility of Results
TL;DR:
The progress of research in this area on one trait and multiple traits by maximum likelihood and Bayesian methods is reviewed.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(Web of Science)
13. Climate Action
(Web of Science)
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Plasmid Transduction Using Bacteriophage Phi adh for Expression of CC Chemokines by Lactobacillus gasseri ADH
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(12), 3878–3885.
MeSH headings : Bacteriophages / genetics; Chemokines, CC / biosynthesis; Chemokines, CC / genetics; Chemokines, CC / metabolism; Genetic Engineering; Humans; Lactobacillus / genetics; Lactobacillus / metabolism; Plasmids; Recombinant Proteins / biosynthesis; Recombinant Proteins / genetics; Recombinant Proteins / metabolism; Transduction, Genetic
TL;DR:
The findings of this study lend support to the potential use of transduction in vaginal Lactobacillus species as a novel strategy for the prevention of HIV infection across mucosal membranes.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Dietary fat-dependent transcriptional architecture and copy number alterations associated with modifiers of mammary cancer metastasis
Clinical & Experimental Metastasis, 27(5), 279–293.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Targeted expression of anthrax protective antigen by Lactobacillus gasseri as an anthrax vaccine
FUTURE MICROBIOLOGY, 5(8), 1289–1296.
author keywords: anthrax vaccine; dendritic cell; high copy expression; Lactobacillus gasseri; oral vaccine delivery; probiotic
MeSH headings : Administration, Oral; Animals; Anthrax / prevention & control; Anthrax Vaccines / administration & dosage; Anthrax Vaccines / genetics; Anthrax Vaccines / immunology; Antibodies, Bacterial / blood; Antibodies, Neutralizing / blood; Antigens, Bacterial / genetics; Antigens, Bacterial / immunology; Antitoxins / blood; Bacterial Toxins / genetics; Bacterial Toxins / immunology; Genetic Vectors; Lactobacillus / genetics; Lactobacillus / immunology; Mice; Plasmids; Recombinant Fusion Proteins / genetics; Recombinant Fusion Proteins / immunology; Survival Analysis; T-Lymphocytes / immunology
TL;DR:
Improvement of this improved expression vaccine strategy reduced the number of inoculations and length of the boosting period, leading to animal protection via efficacious bacterial adjuvanticity and safe oral delivery of this vaccine to mucosal immune cells, including dendritic cells.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science; OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
QTL Identification Using Combined Linkage and Linkage Disequilibrium Mapping for Milk Production Traits on BTA6 in Chinese Holstein Population
ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES, 23(10), 1261–1267.
author keywords: Fine Mapping; QTL; Bos Taurus autosome 6; Milk Production Traits
TL;DR:
The aim of the present study was to refine the position of previously detected quantitative trait loci (QTL) on bovine chromosome 6 affecting milk production traits in Chinese Holstein dairy cattle.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Genotype-by-diet interactions drive metabolic phenotype variation in Drosophila melanogaster
Genetics, 185(3), 1009–1019.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Dissecting comimetic radiations in Heliconius reveals divergent histories of convergent butterflies
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 107(16), 7365–7370.
author keywords: amplified fragment length polymorphism; Heliconius erato; Heliconius melpomene; Mullerian mimicry; mtDNA
MeSH headings : Amplified Fragment Length Polymorphism Analysis; Animals; Butterflies / genetics; Butterflies / physiology; Cluster Analysis; DNA, Mitochondrial / metabolism; Evolution, Molecular; Geography; Likelihood Functions; Models, Genetic; Molecular Sequence Data; Phenotype; Phylogeny; Polymorphism, Restriction Fragment Length; Species Specificity; Time Factors
TL;DR:
The results suggest that H. erato originated on the western side of South America whereas H. melpomene originated in the east, and that each of the three main wing pattern phenotypes originated and/or was lost multiple times in each species.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
15. Life on Land
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
De novo mutations in the gene encoding the synaptic scaffolding protein SHANK3 in patients ascertained for schizophrenia
Proceedings of the National Academy of Sciences of the United States of America, 107(17), 7863–7868.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Arabidopsis thaliana Chromosome 4 Replicates in Two Phases That Correlate with Chromatin State
PLoS Genetics, 6(6), e1000982.
Ed(s): G. Copenhaver
MeSH headings : Arabidopsis / cytology; Arabidopsis / genetics; Chromatin / genetics; Chromosomes, Plant; DNA Replication; Epigenesis, Genetic; Flow Cytometry; Oligonucleotide Array Sequence Analysis; Replicon; S Phase
TL;DR:
The similarity of the replication profiles for early and mid S phase cells indicates that replication origin activation in euchromatin is stochastic, and distinct patterns of association of H3K56ac with gene expression and early replication provide evidence that H3k56ac may be associated with initiation zones and replication origins.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
15. Life on Land
(OpenAlex)
Sources: Web Of Science, NC State University Libraries, Crossref, ORCID, NC State University Libraries
Added: August 6, 2018
2010 journal article
Direct measure of the de novo mutation rate in autism and schizophrenia cohorts
American Journal of Human Genetics, 87(3), 316–324.
Source: NC State University Libraries
Added: August 6, 2018
2010 article
Toxicogenetics: population-based testing of drug and chemical safety in mouse models (vol 11, pg 1127, 2010)
Rusyn, I., Gatti, D. M., Wiltshire, T., Kleeberger, S. R., & Threadgill, D. W. (2010, September). PHARMACOGENOMICS, Vol. 11, pp. 1344–1344.
MeSH headings : Animals; Disease Models, Animal; Drug Evaluation, Preclinical / methods; Drug-Related Side Effects and Adverse Reactions / genetics; Humans; Mice; Quantitative Trait Loci / genetics; Species Specificity; Toxicogenetics / methods
TL;DR:
It is posited that appropriate genetically defined mouse models may be combined with the limited data from human studies to not only discover the genetic determinants of susceptibility, but to also understand the molecular underpinnings of toxicity.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
11. Sustainable Cities and Communities
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 article
Genomic Evolution of Domesticated Microorganisms
ANNUAL REVIEW OF FOOD SCIENCE AND TECHNOLOGY, VOL 1, Vol. 1, pp. 397–414.
author keywords: lactic acid bacteria; fermentation; food; adaptation; mutation
MeSH headings : Adaptation, Biological; Evolution, Molecular; Fermentation; Food Handling; Food Microbiology / methods; Fungi / genetics; Fungi / metabolism; Genome, Bacterial; Humans; Lactobacillales / genetics; Lactobacillales / metabolism; Microbial Viability; Selection, Genetic
TL;DR:
This review highlights the evolutionary traits influenced by the domestication process as these microbes adapted to nutrient-rich foods developed by humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
2. Zero Hunger
(OpenAlex)
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Maternal Dioxin Exposure Combined with a Diet High in Fat Increases Mammary Cancer Incidence in Mice
ENVIRONMENTAL HEALTH PERSPECTIVES, 118(5), 596–601.
author keywords: COMT; CYP1B1; dioxin; high-fat diet; mammary cancer; puberty
MeSH headings : Animals; Aryl Hydrocarbon Hydroxylases / genetics; Catechol O-Methyltransferase / genetics; Cocarcinogenesis; Cytochrome P-450 CYP1B1; Dietary Fats / administration & dosage; Dietary Fats / adverse effects; Environmental Pollutants / administration & dosage; Environmental Pollutants / toxicity; Estrogens, Non-Steroidal / administration & dosage; Estrogens, Non-Steroidal / toxicity; Female; Gene Expression / drug effects; Humans; Mammary Neoplasms, Experimental / etiology; Mammary Neoplasms, Experimental / genetics; Mammary Neoplasms, Experimental / pathology; Mice; Polychlorinated Dibenzodioxins / administration & dosage; Polychlorinated Dibenzodioxins / toxicity; Pregnancy; Prenatal Exposure Delayed Effects / etiology; Risk Factors
TL;DR:
The data suggest that the HFD increases sensitivity to maternal TCDD exposure, resulting in increased breast cancer incidence, by changing metabolism capability, which provides a mechanism to explain epidemiological data linking early-life T CDD exposure and diets high in fat to increased risk for breast cancer in humans.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(OpenAlex)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Functional Roles of Aggregation-Promoting-Like Factor in Stress Tolerance and Adherence of Lactobacillus acidophilus NCFM
APPLIED AND ENVIRONMENTAL MICROBIOLOGY, 76(15), 5005–5012.
MeSH headings : Adhesins, Bacterial / chemistry; Adhesins, Bacterial / genetics; Adhesins, Bacterial / metabolism; Anti-Bacterial Agents / toxicity; Bacterial Adhesion; Bile; Detergents / toxicity; Epithelial Cells / microbiology; Fibronectins / metabolism; Gastric Juice; Gene Deletion; Gene Expression Profiling; Lactobacillus acidophilus / drug effects; Lactobacillus acidophilus / genetics; Lactobacillus acidophilus / physiology; Microbial Viability / drug effects; Molecular Weight; Mucins / metabolism; Phylogeny; Protein Binding; Reverse Transcriptase Polymerase Chain Reaction; Sequence Homology, Amino Acid; Sodium Dodecyl Sulfate / toxicity
TL;DR:
R reverse transcriptase-quantitative PCR analysis revealed that the apf gene was highly induced during the stationary phase compared to that during the logarithmic phase, suggesting that the Apf-like proteins may contribute to the survival of L. acidophilus during transit through the digestive tract and, potentially, participate in the interactions with the host intestinal mucosa.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
A conserved role for syndecan family members in the regulation of whole-body energy metabolism
PLoS One, 5(6).
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
hunchback and Ikaros-like zinc finger genes control reproductive system development in Caenorhabditis elegans
Developmental Biology, 339(1), 51–64.
Source: NC State University Libraries
Added: August 6, 2018
2010 journal article
Plasmodium falciparum genome-wide scans for positive selection, recombination hot spots and resistance to antimalarial drugs
Nature Genetics, 42(3), 268–113.
Source: NC State University Libraries
Added: August 6, 2018
2010 article
The role and potential of probiotic bacteria in the gut, and the communication between gut microflora and gut/host
O'Flaherty, S., & Klaenhammer, T. R. (2010, April). INTERNATIONAL DAIRY JOURNAL, Vol. 20, pp. 262–268.
TL;DR:
This review outlines the recent important advances in this exciting area of research, which has led to a greater understanding of the critical interface between gut microbiota, probiotic bacteria and the host.
(via Semantic Scholar)
UN Sustainable Development Goal Categories
3. Good Health and Well-being
(Web of Science)
Source: Web Of Science
Added: August 6, 2018
2010 journal article
Individual variation in pheromone response correlates with reproductive traits and brain gene expression in worker honey bees
PLoS One, 5(2).
Source: NC State University Libraries
Added: August 6, 2018
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